TCONS_00001934-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00001934-protein
Unique NameTCONS_00001934-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length744

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00001934-protein ID=TCONS_00001934-protein|Name=TCONS_00001934-protein|organism=Clytia hemisphaerica|type=polypeptide|length=744bp
MYGFIHCCLHDLILKQFGEETWNAIIKEAGVNLAGGEYIIHRVYSDQETM
KLVTVAQKLSGIPLNDILETFGNHFYKYCKQSGYDRVLKILGRTLREFLC
NLDALHDHLASIYPGMNAPSFRASERPDGGLDLHYYSNRDGLGYIVIGIM
KTVARECLNTEIEIYIDKEKENKDDHVVFAVFEKTATQCPSIPSITFPPA
SKFEHRSSSITSFKALFRRKKHFMSIKSFTEAFPFHVVFDRNLNIKQCGS
SISKYIEQSYFEVNGQTNRKKKGKIKYPFTDAFRLIRPKMNFTFQNILHH
INTVFVVASKHRLELIREDSDGNISTPRPEDLKKGLNRGRHTGSAYSAIL
SAASVCTPSLVTSTTRASELRLKGQMIYLPKTDCLLFLCSPRVGSLEELR
RRGLYLSDFPLHDSTREVILTKKEHQQDRQLVKRIEDSNNGLKILKTKLV
HNKNITDELLHELLPPIVAQQLRLNLPVLAESYDMVTILFSDLVGFTALC
SNEQVVPMDIIKLLNKLYTMFDVISHMHNVFKVETIGDAYMGVCGIPQPI
EHHAKHVVEMAMDMLECVQNVISPVDAHPVKIRVGLHSGSCMAGVVGKKT
PRYCLFGKHVTLANKMESGSSPGKVNVSIETKKFLSNEEWSFEENANPNP
MECYFIKPKKIQPEKLAEKKQFLKQLANMETHLKEGSPAMQRKVIRPLSK
VLETKEISATVIDNNNSLPALNEGVTTKLTMNGGGCPFSHGMVK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001000XLOC_001000Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00001934TCONS_00001934Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001054A/G_cyclase
IPR011644Heme_NO-bd
IPR011645HNOB_dom_associated
IPR029787Nucleotide_cyclase
IPR024096NO_sig/Golgi_transp_ligand-bd
Vocabulary: Biological Process
TermDefinition
GO:0009190cyclic nucleotide biosynthetic process
GO:0035556intracellular signal transduction
GO:0006182cGMP biosynthetic process
Vocabulary: Molecular Function
TermDefinition
GO:0016849phosphorus-oxygen lyase activity
GO:0020037heme binding
GO:0004383guanylate cyclase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006182 cGMP biosynthetic process
biological_process GO:0009190 cyclic nucleotide biosynthetic process
biological_process GO:0035556 intracellular signal transduction
molecular_function GO:0004383 guanylate cyclase activity
molecular_function GO:0020037 heme binding
molecular_function GO:0016849 phosphorus-oxygen lyase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseSMARTSM00044cyc_6coord: 451..646
e-value: 1.4E-69
score: 247.1
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePFAMPF00211Guanylate_cyccoord: 480..646
e-value: 5.7E-54
score: 182.4
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclaseGENE3D3.30.70.1230coord: 474..670
e-value: 3.2E-52
score: 176.4
IPR001054Adenylyl cyclase class-3/4/guanylyl cyclasePROSITEPS50125GUANYLATE_CYCLASE_2coord: 487..617
score: 43.225
IPR011644Heme-NO bindingPFAMPF07700HNOBcoord: 2..164
e-value: 4.0E-52
score: 176.4
IPR011645Haem NO binding associatedPFAMPF07701HNOBAcoord: 224..472
e-value: 1.1E-52
score: 178.5
NoneNo IPR availableGENE3D3.90.1520.10coord: 1..191
e-value: 9.5E-66
score: 220.5
NoneNo IPR availableCDDcd07302CHDcoord: 486..644
e-value: 1.31296E-50
score: 173.534
IPR029787Nucleotide cyclaseSUPERFAMILY55073Nucleotide cyclasecoord: 477..639
IPR024096NO signalling/Golgi transport ligand-binding domainSUPERFAMILY111126Ligand-binding domain in the NO signalling and Golgi transportcoord: 1..181

Blast
[Close]
BLAST of TCONS_00001934-protein vs. Swiss-Prot (Human)
Match: GCYB1 (Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens GN=GUCY1B3 PE=1 SV=1)

HSP 1 Score: 458.373 bits (1178), Expect = 8.077e-153
Identity = 261/682 (38.27%), Postives = 387/682 (56.74%), Query Frame = 0 
Query:    1 MYGFIHCCLHDLILKQFGEETWNAIIKEAGVNLAGGEYIIHRVYSDQETMKLVTVAQKLSGIPLNDILETFGNHFYKYCKQSGYDRVLKILGRTLREFLCNLDALHDHLASIYPGMNAPSFRASERPDG-GLDLHYYSNRDGLGYIVIGIMKTVARECLNTEIEIYIDKEKENKDDHVVFAVFEKTATQCPSIPSITFPPASKFEHRSSSITSFKALFRRKKHFMSIKSFTEAFPFHVVFDRNLNIKQCGSSISKYIEQSYFEVNGQTNRKKKGKIKYPFTDAFRLIRPKMNFTFQNILHHINTVFVVASKHRLELIREDSDGNISTPRPEDLKKGLNRGRHTGSAYSAILSAASVCTPSLVTSTTRASELRLKGQMIYLPKTDCLLFLCSPRVGSLEELRRRGLYLSDFPLHDSTREVILTKKEHQQDRQLVKRIEDSNNGLKILKTKLVHNKNITDELLHELLPPIVAQQLRLNLPVLAESYDMVTILFSDLVGFTALCSNEQV--VPMDIIKLLNKLYTMFDVISHMHN---VFKVETIGDAYMGVCGIPQPIEHHAKHVVEMAMDMLECVQNVISPVDAHPVKIRVGLHSGSCMAGVVGKKTPRYCLFGKHVTLANKMESGSSPGKVNVSIETKKFL-----SNEEWSFEE------NANPNPMECYFIKPKKIQPEK 665
            MYGF++  L  L+++ +G E W  I KEA ++   G++++  +Y D +T  LV  A K+  +   +IL+ FG  F+ +C++SGYD +L++LG  +REFL NLDALHDHLA+IYPGM APSFR ++   G GL LHYYS R+GL  IVIGI+KTVA++   TEI++ + +++  + DH  F + EK + +        +    +FE   +           ++  +S  +F +AFPFH++FDR+L + QCG++I + + Q            + G         F L+RP ++ +F  IL HINTVFV+ SK          +G +   + E                         C   L  + T  S LRLKGQMIYLP+ D +LFLCSP V +L++L RRGLYLSD PLHD+TR+++L  ++ +++ +L + +E   + L++    L   K  TD LL+ +LPP VA +LR   PV A+ YD VTILFS +VGF A CS        M I+ LLN LYT FD ++       V+KVET+GD YM V G+P+P  HHA+ +  +A+DM+E    V   VD   V+I +G+H+G  + GV+G++ PRYCLFG  V L ++ E+    GK+NVS  T + L     S+ ++  E            PM+ +F+  K    E+
Sbjct:    1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLD-EEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKE-----EDFYEDLDRFEENGT-----------QESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQL-----------QPGNCS--LLSVFSLVRPHIDISFHGILSHINTVFVLRSK----------EGLLDVEKLE-------------------------CEDEL--TGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQV--QVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEE 613
The following BLAST results are available for this feature:
BLAST of TCONS_00001934-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GCYB18.077e-15338.27Guanylate cyclase soluble subunit beta-1 OS=Homo s... [more]
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