seven transmembrane protocadherin flamingo (polypeptide) - C. hemisphaerica

BLAST of seven transmembrane protocadherin flamingo vs. Swiss-Prot (Human)
Match: CELR2 (Cadherin EGF LAG seven-pass G-type receptor 2 OS=Homo sapiens GN=CELSR2 PE=1 SV=1)

HSP 1 Score: 1144.8 bits (2960), Expect = 0.000e+0
Identity = 779/2536 (30.72%), Postives = 1221/2536 (48.15%), Query Frame = 0

Query:  223 RRRRNI--PIYFEKSLYSVDIFEDTKRDSVIRKLKV------NGGSGKYSFSKTEDPKTDILFKVKSDTGDVILLQELNREDGAERFSIDIRAIDLNDPSNSATTTIRVKVLDVNDNAPTFAESSYSITVDEGQVANKYILTVRATDADEGSNQEIRYSIVNKANVQVP--FQIDPISGAIKSTDVLDRETHPYYNFTVRAEDQGK--VKLHTDVSVSITLRDKNDNSPKFSKDVYKLSIPENTTVGSVVFKLDAVDDDIGQNGVIEFRPLDSNLR--FRINTSTGEIILKEAVDFDKYQRFSRFTVVAFDKGSPPKYANTEVEITIE--DVNDNAPRFAKRIFERTSDIMEDIKVGSFVYKLSARDRDSGPNGDITFKLEDGLPQDFPFELDPKSGEITVSKGLDYETTKSYKFGVIAVDNGHPPKKDTTQVVFNIGNVNDNNPKFKQSSYYKEILEDTRRGEAIEKVEAFDPDQLSNEDFEYAIEEGNSDDCFGI--DPFQGVLFLKCDLDYKRKNMYNLKLRVTDADKKPGYAYFKIEVTDANNNSPRFGQDVYQWNVLENADIGTVIKSVLATDADTGENARITYSLQPGSPIDTFGIVNDTGAITTKKKLDRETTKSYTLVVKASDHGKPFKKFGFATVVITVTDVNDNKPVFTKNLYTFTIEEDAKIGAVVGHLQATDNDEGRNKEVRYQFKERKHEY--FSINAESGSIRTIKLLDRETIERFTFEVLAIDQGTPALQTSTSVIIDIEDVQDSNPVFTEKVYNFTIPENSLV--EVGRIRATLADDAFRHSMVYSFTK--YQTTFRIASLQGIIRANSPLDYEKQHHYQLHVRVVSDSGREDTAVVNVHVEDVNDHPPILEDFYIFLNALNGKYDPMF------RVPAEDPDVSSVLRYGIITGNEHDFISLNDETGELFLKKSIINT-AAEIRILFEVSDGKYADRAYGHILVSEVTDVMVKNSMFIVLNNATRNDFLKATVLRKFKDSLAQIFDVDGSKIVDASKIFILSIEAFRDPRKGNKNAEMLEIAIAVKSKMADTYMTADFLKDKFYLNATAFTR-SGFDLVSFDFWGEYFCGSESCKNLERCSIQWSNTNQISSTIKSKYVIFRGIYFKPALKCECPHRFHGMKCDKPFNMCFMERCNSNGKCISTDDGFSCKCDHGYTGDFCAFDRQTSSCPIQLNLAKNPCGLRGVCSAKSGGGFDCTCPAKGTDTEYCKLSTRYFPKGSYIAMPGLKKQQRNFDISFQFRTFQANAVLLYNGRYSNQNDFIAVEIVDGQVLFSVNFGKSKDNKEQVTTVQSFNAGGVNDGKWHTVKVQLKNKV---------------ISIAVGESCDIETASVLNSQGTHRYCAASTRVQGEMKTLDLTAPALIGGLPDMQRTFLSPVKDFIGCMRNIVFDHNSLDLSNYLHNFGSAANCPAPAPSCNDAYCTKYVNGDCHETLDGPKCSCRSRFVGQRC-EKAAEPIRLNANSVLVVDDSQASGSGFSAWRYSMVVKTTQKDAVILEETINGVDG-RLMLKNGYLQYHHKSKLI----LVLDSFFMANGKWNQIQIKWTAN----RLYLSSLYDQHSVSTPLP--LTTLSLKMTSFGGTGN------NKLLACIKAF----TYNG-NDINLLHTSNKHVQKGCLESSLCDTLDCGTGT-CQITSGVAQCHCNGAGYKGPQCLDICKDSPC-NTGTCKHSSSSLSGYVCDCPIGFTGEHCEIAKQKKCPPKTFGKDYCGPCDCKLHENFNETCDPDGQMEPYSYPGKCFCNDDYYLKGG--VCVKCNCLLEGSESSVCDKKTGQCKCKANVIGMKCDKCPGAWQEI-TNGCGEIN-NSCPRTYVDGIWWRRAARGVTQRERCPFNAVGNATRHCDPRKGWQAPDFFDCTSQLFSNIQTLLKPVLTSGKRMTKDLVTSISYKLDFAVSAPKLTFTPHAFYGKDIMIGYDALRLMISYEGNQTAAHLVSADEEQFVGNLLKSAGKLFQTSLSPFWDSIQKKYSGTAGLMKEMERFVNILSKNLAYIKRNRNRRSVTLNTYSQATSNIYFEIKPMVRGN----------------SVDEEKFITLPDSLSSRHIDYYMWKDPSVSVRISDAIFLD--HDELFRINEVNIGLIIYKTLGHLLPTNFDQDNREEGRKYALNVYSDVVTLTIPSIKSLHPLT-EIQITYKNVSQLNSTSTSLVCAFWNYSLSGTVSGGWSPNGCVTKMEVNSSDVTCVCNRMASFALV----GFQYTEIIPRVYQPAFLVYIALAVAMLLFLIVFLVFLCLSQLKSNANSIHKNLAFVLLLGWIVFTFAINRPDVGKANCRIIAILIHYCLTCAFSWLMVEALHMYRMILEPRDINYGQMMFYYFIGWGAPVIVVGVTAGLKPDGYGTPEFCWISAKVNDS-VWTYVAPI-FAIIAGTFIIIILALASSCEKANIKGKKAKLARIRYRLAISFFFLFIMMVTVFGGLLEVSFDMTLLTYIFAGTCALEGVYMFLFYVCFNRKVRREAYNAYKR 2657
            RR+RN+     F+   Y   + E+    + +  L+         G  +Y+     D +++  F +   TG V   +EL+RE  +      + A D   P  SA  T+ + V D ND+ P F +  Y  ++ E       +LTVRATD D   N  I Y ++  +       F+IDP SG I++   +DRE    Y  TV A DQG+      T  +V +++ D NDN+P+FS+  Y + + E+ T G+ V ++ A D D G N V+ +  +  N R  F ++  TG + +   +D++  + ++   V A D G PP  +N    +T++  D+NDNAP F    F+ T  ++E + +G  V  + A D D+G N  + ++L  G+  DFPF ++  +G I+V+  LD E    Y FGV A D+G P    +  V   + +VNDNNP F Q  Y   + ED   G ++  V A D D  ++    Y I  GN+ + F I      G++ L   LDYK +  Y L +  +D  ++   A   + VTDAN + P F    Y  NV E+   GT +  + ATD DTGENARITY ++    I  F I  DTGA+TT+ +LD E   SYTL + A D+G P +K     + I V DVNDN P F ++ Y  ++ ED      V  + ATD D G N  V Y F+        F + + SG +RT++ LDRE + ++     A+D+G P  +T   V + + DV D+ PVF +  ++  + ENS +   V R+ AT  D+     ++Y   +      F++    G + A   LDYE +  Y L ++  S +     A V+V + D ND+PP+L +F I  N         F      RVPA DPD+S  L Y    GNE   + LN  TGEL L +++ N    E  +   VSDG ++  A   + V+ +TD M+ +S+ + L + +   FL + +L  F  ++A         +V      + +++   D   G+     L +           ++ ++ L+++ YLN +  T  S   ++ FD   +  C  E C+N  RC +     +  +  I S  V+FR I+    L+C CP  F G  C+   ++C+   C  +G+C S + G++C C  GYTG+ C    ++  C          C   G C     GGF C CP+   +  YC+++TR FP  S+I   GL+ Q+ +F ++  F T + + +LLYNGR++ ++DF+A+E++  QV  + + G+S       TTV  F  GGV+DG+WHTV+++  NK                +++   + CD   A    S   +  CAA     G  K+LDLT P L+GG+PD+  +F   ++ F+GCMRN+  D   +D+++++ N G+   CPA    C+   C  +  G C    D   C C   F G+ C ++ A P     +S++         S    W  S++ +T Q D V+L+    G     L L+ G++    +   +    L L+     +G W+  Q+   A+       LS  Y Q      L   L  L L   + GG              C++      T  G N ++  H  + +V++GC     CD+  C   + C        C C+  GY G  C ++C  +PC +   C    S+  GY C+CP  + G +CE    + CP   +G   CGPC+C + + F+  C+           G+C C +++Y   G   C+ C+C   GS S VCD + GQC CK  VIG +CD+C   + E+ TNGC E+N +SCPR    GIWW R   G+     CP  + G A RHCD  +GW  P+ F+CTS  FS ++   + +    +R    L +  S +L   +     T     ++G D+ + Y     ++++E  Q    L +  +  F  NLL+    L  T+    W+ IQ+   GTA L++  E + + L++N+         R   L+ ++  T NI   +  + +GN                  D E  + LP+S+            P  +    +       H EL +  E    +IIY+TL  LLP N+D D R         + + VV++++   + L P   +  +T +         T  +C FWN+S+  + +GGWS  GC      N S V+C CN M SFA++      +  EI+P       L Y+AL V +   L+ F     L  L+SN + I +NL   L L  +VF   IN+ D+  A C +IAIL+H+   C FSW ++EALH+YR + E RD+N G M FYY +GWG P  + G+  GL P+GYG P+FCW+S  + D+ +W++  P+ FA+    F+ I+ A AS   +     KK  ++     L  SF  L ++  T    LL V+ D  L  Y+FA    ++G ++FL YV  +++VR+    A  R
Sbjct:  170 RRKRNVNTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDRETKSTHV-FRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYT-LRVRAQDGGRPP-LSNVSGLVTVQVLDINDNAPIFVSTPFQAT--VLESVPLGYLVLHVQAIDADAGDNARLEYRLA-GVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD--AHSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQ-DTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME--DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIP-QKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATS-APLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSPERFL-SPLLGLFIQAVAATLATPPDHVV------VFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYLNRSLLTAISAQRVLPFD---DNICLREPCENYMRC-VSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRC------TPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQVTTRSFPAHSFITFRGLR-QRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGES------TTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTC--HNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPIS--QPWYLSLMFRTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGIPGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSCD-PGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCN--------KTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVTTNGC-EVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHCDEHRGWLPPNLFNCTSITFSELKGFAERL----QRNESGLDSGRSQQLALLLR--NATQHTAGYFGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSALLDTANKRHWELIQQTEGGTAWLLQHYEAYASALAQNM---------RHTYLSPFTIVTPNIVISVVRLDKGNFAGAKLPRYEALRGEQPPDLETTVILPESVFRETPPVVRPAGPGEAQEPEELARRQRRHPELSQ-GEAVASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFR-NESHVSCQCNHMTSFAVLMDVSRRENGEILPL----KTLTYVALGVTLAALLLTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGINQADLPFA-CTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLS--IYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQRQGFEKKGPVS----GLQPSFAVLLLLSATWLLALLSVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKALKLACSR 2626