TCONS_00003203-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00003203-protein
Unique Name	TCONS_00003203-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1673

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00003203-protein ID=TCONS_00003203-protein|Name=TCONS_00003203-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1673bp
FCRLCVGVLKQSGIIFKIPTIHSMLRKKMADKKDERMRDKSKVHSGRSGK
KLNEQEICVGEELKIAVSVAVDRFINDEAQTELEFPSSLTANERAYVHRY
CKDLGLITKSRGKGNKRYLTIYKVAEKSVTVNGRLTLSRSSSGIINSLLQ
DLPVTSRDKHELSGQKLHKGIVNEQNKILARENRLVLGNAPHIPPDAKET
DLKKKAKDLPIYQFKDAIVDAVAKNQVVMIAGDTGSGKTTQVAQFLLEKH
HKSRVPCRIICTQPRRLSAISIAERVSAERGERVGQTVGYQIRLESKLSS
KTLLHFCTTGVLLRLLMVGHKCLSNLTHIIVDEIHERDCLSDYLLISLRD
ILKSYKKLKVILMSAALNVDLFTSYFGKCPFIHVNGSTHDVKTFFLEDIL
KQTGYLNKGMRKMLQDDDRSLFKIEEKSTAAEEVMKLLKDDKKEETKEDA
AEEEKAATPKEDVLSDGDHHNASDVEVESDTESENEDSQKVDGEGAGDGA
VCEEEDDDVEIEKDEDDLGEDEGIAEDIDKLDIGGSDVDENDDEEDNEPI
GVDEEDEDDAGDGDEQNEESKNTSSKEMDTALAQAWLNGDDEAFDQIIHL
IMNENVNIDYQHSDTKMTSLIVAAARGNQTLTEQLIELGAKLDIRDPNNN
RDALEWANHFSQNHVVEYLKGVSQSVSNDSSATLDETSTEEDLTENDKRR
LELYHKSFDDQRVDISLILCLLGQICQKQQLKGSILIFLPGYDEIVSLRD
KLKQDKEFSKRSKYQVLMLHSMLPPGNQRKVFGRPPSGVQKIILSTNIAE
TGITIDDVVCVIDSGKVKEKSHDAISCVSTLRTVWISKASAIQRRGRAGR
CLPGICYHLFSQDRFHHFQTYQDAEMLRVPIHALCLQTKMLAPVNVSITD
YLGKAPEPPSNLITRSSIKMLKAISALDENEEMTDLGKLLIELPIDPQFG
KMILIGMSLKCLEPSIIIACCSSYKEPFLLPNVASQKSSAANAKLKLSSD
SYSDQIAMLRAFQGWQRAKREGKEKVYCARNFISLGTMEMVSGMRRQIIG
LLRSLGLVRMKGPGNMRDLNTNSRNWSIIKAVVGSGLYPNFIKVDKENKV
LVSEKEKKVTIHNSSVLVARSEDKVQSTVSRANKLNSTISSLPLNWLVYE
ELSRLYYSVQIRSVSVLSSVAVALIGGPCLSYDHSSLRLKSSRNKKGRGR
HGNDRGHHKDNFFQESDSEEESGQDSNTASFKIDDWMSFTGDDSTLYALA
MLRIKFLALFSKHIQIPSKPWTQADSDIVQAIADVLIKEEQVVGLVNPAT
KDIEKRRGYERKYERYDRPRGRGRGGGPSRPYARREYNSRYERRYHGRDA
PPDADAPENDGKLSDHESTGGNDEKRRERSYFILKCNNEKNMGISFDRSI
WATTKSNEKRLHRAFKDSEEVYLVFSVQGSGRFQGVAKMISGISDKQCED
FGSANLGGVFDIEWIHQEELPFQATQHLANPWNDNKKVQISRDAQELEPS
VGKALVNLWDKDGGGAPANADAGSTPRDERAEVSSPDEQLLPTSDEVSPQ
QQQEFYPPQEIYAGGSAPEGENQPYVEEYPMYSPPPFSPQFIPDFQQVPA
HYAPAPHMGYQQSPYPAAGAPAMYAQHAPPQGNMPAYRQQEYYSFQYSPP
RRGVDVYQRQESSEQKMRGGYRS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_001768	XLOC_001768	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00003203	TCONS_00003203	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001650	Helicase_C
IPR001374	R3H_dom
IPR014001	Helicase_ATP-bd
IPR007502	Helicase-assoc_dom
IPR011545	DEAD/DEAH_box_helicase_dom
IPR007275	YTH_domain
IPR020683	Ankyrin_rpt-contain_dom
IPR002110	Ankyrin_rpt
IPR027417	P-loop_NTPase

Vocabulary: **Molecular Function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0003723	RNA binding
GO:0005515	protein binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004386	helicase activity
molecular_function	GO:0003676	nucleic acid binding
molecular_function	GO:0005515	protein binding
molecular_function	GO:0003723	RNA binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001650	Helicase, C-terminal	SMART	SM00490	helicmild6	coord: 746..852 e-value: 3.5E-18 score: 76.4
IPR001650	Helicase, C-terminal	PFAM	PF00271	Helicase_C	coord: 721..850 e-value: 1.3E-16 score: 60.8
IPR001650	Helicase, C-terminal	PROSITE	PS51194	HELICASE_CTER	coord: 721..892 score: 15.344
IPR001374	R3H domain	SMART	SM00393	R3H_4	coord: 46..124 e-value: 1.2E-9 score: 48.0
IPR001374	R3H domain	PFAM	PF01424	R3H	coord: 71..123 e-value: 4.1E-10 score: 39.4
IPR001374	R3H domain	GENE3D	3.30.1370.50		coord: 61..166 e-value: 1.4E-12 score: 46.8
IPR001374	R3H domain	PROSITE	PS51061	R3H	coord: 61..125 score: 13.67
IPR001374	R3H domain	SUPERFAMILY	82708	R3H domain	coord: 69..124
IPR014001	Helicase superfamily 1/2, ATP-binding domain	SMART	SM00487	ultradead3	coord: 207..394 e-value: 5.5E-27 score: 105.7
IPR014001	Helicase superfamily 1/2, ATP-binding domain	PROSITE	PS51192	HELICASE_ATP_BIND_1	coord: 219..385 score: 19.896
IPR007502	Helicase-associated domain	SMART	SM00847	ha2_5	coord: 916..1009 e-value: 1.0E-19 score: 81.5
IPR007502	Helicase-associated domain	PFAM	PF04408	HA2	coord: 918..1000 e-value: 3.7E-17 score: 62.4
IPR011545	DEAD/DEAH box helicase domain	PFAM	PF00270	DEAD	coord: 217..368 e-value: 5.9E-9 score: 35.8
None	No IPR available	GENE3D	3.40.50.300		coord: 606..873 e-value: 3.5E-46 score: 156.4
None	No IPR available	GENE3D	3.40.50.300		coord: 208..369 e-value: 8.4E-30 score: 103.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1648..1673
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1314..1376
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1507..1582
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 439..577
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1191..1227
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 29..49
None	No IPR available	CDD	cd00204	ANK	coord: 572..669 e-value: 8.88312E-7 score: 48.1486
None	No IPR available	CDD	cd00046	DEXDc	coord: 226..365 e-value: 2.36916E-26 score: 106.653
None	No IPR available	CDD	cd00079	HELICc	coord: 713..859 e-value: 1.58101E-10 score: 59.5589
IPR007275	YTH domain	PFAM	PF04146	YTH	coord: 1380..1510 e-value: 2.5E-43 score: 147.1
IPR007275	YTH domain	PROSITE	PS50882	YTH	coord: 1379..1509 score: 40.311
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 577..669 score: 14.557
IPR020683	Ankyrin repeat-containing domain	SUPERFAMILY	48403	Ankyrin repeat	coord: 572..673
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 615..647 score: 9.511
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 700..863 coord: 222..370

Blast

[Close]

BLAST of TCONS_00003203-protein vs. Swiss-Prot (Human)
Match: YTDC2 (Probable ATP-dependent RNA helicase YTHDC2 OS=Homo sapiens GN=YTHDC2 PE=1 SV=2)

HSP 1 Score: 672.544 bits (1734), Expect = 0.000e+0
Identity = 345/754 (45.76%), Postives = 489/754 (64.85%), Query Frame = 0

Query:  558 DDAGDGDEQNEESKNTSS------KEMDTALAQAWLNGDDEAFDQIIHLIMNENVNIDYQHSDTKMTSLIVAAARGNQTLTEQLIELGAKLDIRDPNNNRDALEWANHFSQNHVVEYLKGVSQSVSNDSSATLDETSTEE----DLTENDKRRLELYHKSFDDQRVDISLILCLLGQICQKQQLKGSILIFLPGYDEIVSLRDK-LKQDKEFSKRS-KYQVLMLHSMLPPGNQRKVFGRPPSGVQKIILSTNIAETGITIDDVVCVIDSGKVKEKSHDAISCVSTLRTVWISKASAIQRRGRAGRCLPGICYHLFSQDRFHHFQTYQDAEMLRVPIHALCLQTKMLAPVNVSITDYLGKAPEPPSNLITRSSIKMLKAISALDENEEMTDLGKLLIELPIDPQFGKMILIGMSLKCLEPSIIIACCSSYKEPFLLPNVASQKSSAANAKLKLSSDSYSDQIAMLRAFQGWQRAKREGKEKVYCARNFISLGTMEMVSGMRRQIIGLLRSLGLVRMKGPGNMRDLNTNSRNWSIIKAVVGSGLYPNFIKVDKENKVLVSEKEKKVTIHNSSVLVARSEDKVQSTVSRANKLNSTISSLPLNWLVYEELSRLYYSVQIRSVSVLSSVAVALIGGPCLSYDHSSLRLKSSRNKKGRGRHGNDRGHHKDNFFQESDSEEESGQDSNTASFKIDDWMSFTGDDSTLYALAMLRIKFLALFSKHIQIPSKPWTQADSDIVQAIADVLIKEEQVVGLVNPA 1299
            DD GD        K+ +       KEMD  L+  WL+ D +AF Q+ HLI+ ENV++DY+HS+T  T+L+VAA RG  +  EQLI +GA +  +  +N   AL+WA HF Q  +V+ L+  S ++       LDE+S  +    DL+  D+  L+ YH SFDD++VD+ LI+ LL  IC      G++LIFLPGYDEIV LRD+ L  DK F+  + +YQV MLHS +   +Q+KV   PP+GV+KIILSTNIAET IT++DVV VIDSGKVKEKS DA++ V+ L+ VWISKASAIQR+GRAGRC PGIC+ LFS+ RF +   +Q  E+LR+P+  LCL TK+LAPVN  I D+L KAPEPP  LI R++++MLK I A+D  E++T+LG  L +LP++P  GKM+L  + LKCL+P + IAC  +Y++PF+LP  ASQK +A   + + ++ ++SD +A+LRAFQ WQ+A+ +G E+ +C +NF+S  TME++ GMR Q++G LR+ G VR +G G++RD+NTNS NW+++KA + +G+YPN + VD+EN VL   KEKKV  H +SVL      K+      AN   + I +LP +WL+Y+E++R +    IR  S ++ V + +  GP      ++L+  SS    G     ND           SDSE E    +N A+ K+D+W+ FT +      L  LR K+ +LF + ++ PSKPW+Q D   ++AI  VL  EEQ  GL  P+
Sbjct:  443 DDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSK-ASNGWMALDWAKHFGQTEIVDLLESYSATLE---FGNLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCD-AGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPP----ANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPA-RLASNALQEPSSFRVDG---IPND----------SSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPS 1173

HSP 2 Score: 358.607 bits (919), Expect = 1.127e-101
Identity = 179/362 (49.45%), Postives = 257/362 (70.99%), Query Frame = 0

Query:   55 QEICVGEELKIAVSVAVDRFINDEAQTELEFPSSLTANERAYVHRYCKDLGLITKSRGKGNKRYLTIYKVAEKSVTVNGRLT--LSRSSSGIINSLLQDLPVTSRDKHELSGQKLHKGI--VNEQNKILARENRLVLGNAPHIPPDAKETDLKKKAKDLPIYQFKDAIVDAVAKNQVVMIAGDTGSGKTTQVAQFLLEKHHKSRVPCRIICTQPRRLSAISIAERVSAERGERVGQTVGYQIRLESKLSSKTLLHFCTTGVLLRLLMVGHKCLSNLTHIIVDEIHERDCLSDYLLISLRDILKSYKKLKVILMSAALNVDLFTSYFGKCPFIHVNGSTHDVKTFFLEDILKQTGYLNKGMRK 412
            ++I + EE+KIAV++A++RF   + Q E+EFPSSLT+ ERA++HR  + LGL++KS+GKG  RYLT+ K  + S T +  +T  L+ ++   + SL+Q  PVT++++ EL  +     +  V  +N+ +++ +  +    P IP    E++     + LP+++ ++ IV  + +N+VV+I G+TGSGKTTQ+ QFLL+   K+ +PCRI CTQPRRL+AI++AERV+AER ER+GQT+GYQIRLES++S KTLL FCT GVLLR LM G   LS +TH+IVDE+HERD  SD+LL  LRD+L+ +  LK+IL SAAL+V+LF  YFG CP I++ G   +VK  FLEDIL+ TGY NK M K
Sbjct:   37 KDIRIDEEVKIAVNIALERFRYGD-QREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKK-KDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLK 396

HSP 3 Score: 178.333 bits (451), Expect = 8.982e-45
Identity = 80/131 (61.07%), Postives = 102/131 (77.86%), Query Frame = 0

Query: 1381 YFILKCNNEKNMGISFDRSIWATTKSNEKRLHRAFKDSEEVYLVFSVQGSGRFQGVAKMISGISDKQCEDFGSANLGGVFDIEWIHQEELPFQATQHLANPWNDNKKVQISRDAQELEPSVGKALVNLWDK 1511
            YFI+K +N +N+ IS  + IW+TT SNE++L+RAF +S  VYLVFSVQGSG FQG ++M S I  ++ +D+GSA LGGVF +EWI +E LPFQ   HL NPWNDNKKVQISRD QELEP VG+ L+ LW++
Sbjct: 1290 YFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLWER 1420

The following BLAST results are available for this feature:

BLAST of TCONS_00003203-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00003203-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
YTDC2	1.127e-101	45.76	Probable ATP-dependent RNA helicase YTHDC2 OS=Homo...	[more]

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TCONS_00003203-protein (polypeptide) - C. hemisphaerica