TCONS_00003553-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00003553-protein
Unique NameTCONS_00003553-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length607

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00003553-protein ID=TCONS_00003553-protein|Name=TCONS_00003553-protein|organism=Clytia hemisphaerica|type=polypeptide|length=607bp
MAKNTNNRKQMAVHVVTKPEEELEFYVDKNIKGQELFDLVCKVIGLRENY
YFGLHYECPNQQPLWLRMDKKVRSELGEQNMSNIKLYLQVQFYPIDVDTG
IIMEQTTHLFFLHVKSEILSESIYCPTEESILLASYAVQAKYGDFDSDIH
KKHFLANDQLLPQRVLAQYKLSADEWEERIVKWYSQHCQGLSRYQAEMEY
LKTAQNLEMYGIGYFRIQNELGTELWLGIHATGINIYESDNQLIPKVSFL
WTEIKNISFKNKQIWIQPMDKEVQDFHFVSLDVAINRKILLLSSGNHDLY
MRSKKEDTMEIQIMKSQAQDAREQRHREQNRLYKEIRRRIEETQARIDME
KRLKDYSGLIDEYRKHLQKAEETTDLLAEKALVAEEEAKLLLKKAADFET
EIKSLRHVCNQKDEEKTYLESHIQSAQINIQQILHESNRRAQETVLLKQE
LDKSRHSEKMATEKLIQISNNYQRAPPIQYSSYAQHQQPPQLQKVQQQPT
QHVQGPQQVSQSHLHYGGAPNYVGGDGEDFTMSVQLERVEYLEKSRHLER
QLTELKTEIEGLKVAGNPDILDRIHLESVGKGETKFSTMQKLQAASTNSR
VQVYQRL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001984XLOC_001984Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00003553TCONS_00003553Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000798Ez/rad/moesin-like
IPR019749Band_41_domain
IPR018980FERM_PH-like_C
IPR011174ERM
IPR019748FERM_central
IPR018979FERM_N
IPR011993PH_dom-like
IPR011259ERM_C_dom
IPR014352FERM/acyl-CoA-bd_prot_3-hlx
IPR000299FERM_domain
IPR029071Ubiquitin-rel_dom
IPR008954Moesin_tail
Vocabulary: Molecular Function
TermDefinition
GO:0008092cytoskeletal protein binding
GO:0003779actin binding
Vocabulary: Cellular Component
TermDefinition
GO:0005856cytoskeleton
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0005856 cytoskeleton
molecular_function GO:0003779 actin binding
molecular_function GO:0008092 cytoskeletal protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 304..387
NoneNo IPR availableCOILSCoilCoilcoord: 538..565
NoneNo IPR availableGENE3D3.10.20.90coord: 11..90
e-value: 1.0E-18
score: 66.5
NoneNo IPR availableGENE3D1.20.5.450coord: 304..352
e-value: 5.4E-5
score: 23.1
IPR000798Ezrin/radixin/moesin-likePRINTSPR00661ERMFAMILYcoord: 584..605
score: 19.7
coord: 121..142
score: 67.68
coord: 77..96
score: 21.67
coord: 218..238
score: 58.99
coord: 167..184
score: 48.15
coord: 24..43
score: 44.44
coord: 293..312
score: 58.61
IPR019749Band 4.1 domainPRINTSPR00935BAND41coord: 125..145
score: 60.02
coord: 112..125
score: 44.35
coord: 44..56
score: 58.17
coord: 195..211
score: 57.23
IPR019749Band 4.1 domainSMARTSM00295B41_5coord: 7..215
e-value: 3.8E-52
score: 189.2
IPR018980FERM, C-terminal PH-like domainSMARTSM01196FERM_C_3coord: 219..308
e-value: 3.8E-22
score: 89.6
IPR018980FERM, C-terminal PH-like domainPFAMPF09380FERM_Ccoord: 219..307
e-value: 3.1E-18
score: 65.8
IPR011174Ezrin/radixin/moesinPIRSFPIRSF002305ERMcoord: 2..607
e-value: 1.2E-160
score: 533.1
IPR019748FERM central domainPFAMPF00373FERM_Mcoord: 104..215
e-value: 1.0E-24
score: 87.1
IPR019748FERM central domainCDDcd14473FERM_B-lobecoord: 106..207
e-value: 1.30417E-25
score: 100.784
IPR019748FERM central domainSUPERFAMILY47031Second domain of FERMcoord: 102..207
IPR018979FERM, N-terminalPFAMPF09379FERM_Ncoord: 21..74
e-value: 7.4E-11
score: 41.7
IPR011993PH domain-likeGENE3D2.30.29.30coord: 210..303
e-value: 8.4E-19
score: 67.3
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 208..345
IPR011259Ezrin/radixin/moesin, C-terminalPFAMPF00769ERMcoord: 344..606
e-value: 1.3E-44
score: 152.8
IPR014352FERM/acyl-CoA-binding protein, 3-helical bundleGENE3D1.20.80.10coord: 91..208
e-value: 1.7E-25
score: 89.0
IPR000299FERM domainPROSITEPS50057FERM_3coord: 11..304
score: 71.575
IPR029071Ubiquitin-related domainSUPERFAMILY54236Ubiquitin-likecoord: 9..94
IPR008954Moesin tail domainSUPERFAMILY48678Moesin tail domaincoord: 527..606

Blast
[Close]
BLAST of TCONS_00003553-protein vs. Swiss-Prot (Human)
Match: MERL (Merlin OS=Homo sapiens GN=NF2 PE=1 SV=1)

HSP 1 Score: 461.84 bits (1187), Expect = 1.678e-156
Identity = 254/608 (41.78%), Postives = 390/608 (64.14%), Query Frame = 0 
Query:    9 KQMAVHVVTKPEEELEFYVDKNIKGQELFDLVCKVIGLRENYYFGLHYECPNQQPLWLRMDKKVRSELGEQNMSN---IKLYLQVQFYPIDVDTGIIMEQTTHLFFLHVKSEILSESIYCPTEESILLASYAVQAKYGDFDSDIHKKHFLANDQLLPQRVLAQYKLSADEWEERIVKWYSQHCQGLSRYQAEMEYLKTAQNLEMYGIGYFRIQNELGTELWLGIHATGINIYESDNQLIPKVSFLWTEIKNISFKNKQIWIQPMDKEVQDFHFVSLDVAINRKILLLSSGNHDLYMRSKKEDTMEIQIMKSQAQDAREQRHREQNRLYKEIRRRIEETQARIDMEKRL---KDYSGLIDEYRKHLQKAEETTDLLAEKALVAEEEAKLLLKKAADFETEIKSLRHVCNQKDEEKTYLESHIQSAQINIQQILHESNRRAQETVLLKQELDKSRHSEKMATEKLIQISNNYQRAP--PIQYSSYAQHQQPPQLQKVQQQPTQHVQGPQQVSQSHLHYGGAPNYVGGDGEDFTMSVQLERVEYLEKSRHLERQLTELKTEIEGLKVAGNPDILDRIHLESVGK-GETKFSTMQKLQAASTNSRVQVYQRL 607
            K   V +VT  + E+EF  +   KG++LFDLVC+ +GLRE ++FGL Y   +    WL+MDKKV     + ++S    +  +   +FYP + +  ++ E T HLFFL VK +IL E IYCP E S+LLASYAVQAKYGD+D  +HK+ FLA ++LLP+RV+  Y+++ + WEERI  WY++H +G +R +AEMEYLK AQ+LEMYG+ YF I+N+ GTEL LG+ A G++IY+ +N+L PK+SF W EI+NIS+ +K+  I+P+DK++  F F S  + +N+ IL L  GNHDL+MR +K D++E+Q MK+QA++ + ++  E+ RL +E + R E  + R ++E+RL   K+ + + +E    L ++EET DLLAEKA + EEEAKLL +KAA+ E E++ ++    + +EEK  +E  +  A++   ++  ES RRA+E   LKQ+L ++R +E+ A +KL++I+      P  PI          PP +      P+ ++ G        L +    ++   D +  +M ++ E+VEY+EKS+HL+ QL ELKTEIE LK+      LD +H E+  + G +K +T++KL   S  SRV  ++ L
Sbjct:   20 KTFTVRIVTM-DAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVA-WLKMDKKVL----DHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH-RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANE---ALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPL------PPDI------PSFNLIG------DSLSF----DFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAKSRVAFFEEL 595
The following BLAST results are available for this feature:
BLAST of TCONS_00003553-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MERL1.678e-15641.78Merlin OS=Homo sapiens GN=NF2 PE=1 SV=1[more]
back to top