TCONS_00004075-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004075-protein
Unique NameTCONS_00004075-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length950

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004075-protein ID=TCONS_00004075-protein|Name=TCONS_00004075-protein|organism=Clytia hemisphaerica|type=polypeptide|length=950bp
VTKLYNGDDGFLRSNITRLMFGSVRASIVIVLKLNNDILVDKMLASAVRG
KLGNLNVKPNTFESTKLGFCVDDCSTNGICVTNSSGGEHCKCQEGFEGDG
IVCIDTNECFVTNGGCQQKCINLIGTFSCACHQGFVLMDDQRSCKVESNQ
LTWSKYCAEEYTQGIEWDETVVGLTLRKTCPNNENKGIAKRFCNKTSKWH
APDLTECIKEGIIQIQNRYALINTSNAIDWTSIEDILSQLVYQTDPTLFV
LYAGDVLTVKDLFTDILSLFTKHQKERDFQQVKIFFNTLNTLLNHVFDRG
NHKAWFGIPQGPAEMFKYLDSIQAMATLLSDFMIDQMETFSTTNPENINN
YQLVDVGSEIDMKIKLLEMRRFNGIQLMQESDHNSSKFSVIYSNQIFKEQ
VMDLLKQKGSYKPIGCWADYNRHAADVSLETKHSTLQDNYLIRTDAIEKC
GAVAYDKKFNVFALHDGGACAAGPLLHQTYKQDGKASNCAFGKGGAFAND
VYEITKFYTGILTISFYQVGHLMKQLLPDSTFPPSASTNTHYGELITTSI
LKYPSSKHSGDNKGQVRIKPTQKNAYIHGITCFKVSYTNGSIEVQDETCE
TRKVDGIVECVCQTMAHYLIVYNYTNVKPVAQAVKEDVYNVLIYISYGIN
CFCIIWSLLIHFYHKTNQASILLHSNLSFVILCTETIYVFGISTDINFDK
VHCKWIIVVFQFFLASLFTWFLTLSWQSYHRLNDVIKQTYRRRRGTYILF
GYGYAVLLTLISMAIFYKDFGNLSHGMCWMSRTILISVFIPPIALLIMFC
VVMLGMVIGIYFSPRSSQSLPDSKTMELEKEEIYSVRDNVRATAIMLPIC
MLTWLFAILRVTENDDFTKYMFFFFNTIQGIAFLTVYCFLNKELAQYYLE
SAETTHITSPPLATINMFKATAYNGNNFKSKRTAIPAEVMYELKQQTARQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002277XLOC_002277Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004075TCONS_00004075Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000742EGF-like_dom
IPR001881EGF-like_Ca-bd_dom
IPR001879GPCR_2_extracellular_dom
IPR000832GPCR_2_secretin-like
IPR013032EGF-like_CS
IPR018097EGF_Ca-bd_CS
IPR017981GPCR_2-like
Vocabulary: Molecular Function
TermDefinition
GO:0005509calcium ion binding
GO:0004930G-protein coupled receptor activity
GO:0004888transmembrane signaling receptor activity
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007166cell surface receptor signaling pathway
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007166 cell surface receptor signaling pathway
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0016020 membrane
molecular_function GO:0005509 calcium ion binding
molecular_function GO:0004930 G-protein coupled receptor activity
molecular_function GO:0004888 transmembrane signaling receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000742EGF-like domainSMARTSM00181egf_5coord: 108..145
e-value: 0.0016
score: 27.7
coord: 69..104
e-value: 0.15
score: 21.2
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 66..104
score: 10.185
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 105..145
e-value: 6.5E-9
score: 45.6
NoneNo IPR availableGENE3D2.10.25.10coord: 113..147
e-value: 4.2E-13
score: 48.9
NoneNo IPR availableGENE3D2.40.155.10coord: 74..112
e-value: 2.5E-9
score: 36.5
NoneNo IPR availableGENE3D1.20.1070.10coord: 625..904
e-value: 1.2E-15
score: 56.7
NoneNo IPR availablePFAMPF14670FXa_inhibitioncoord: 109..144
e-value: 8.1E-10
score: 38.7
NoneNo IPR availableSUPERFAMILY57196EGF/Laminincoord: 102..157
IPR001879GPCR, family 2, extracellular hormone receptor domainPFAMPF02793HRMcoord: 155..209
e-value: 1.1E-5
score: 25.6
IPR001879GPCR, family 2, extracellular hormone receptor domainPROSITEPS50227G_PROTEIN_RECEP_F2_3coord: 130..211
score: 10.461
IPR000832GPCR, family 2, secretin-likePFAMPF000027tm_2coord: 639..881
e-value: 3.3E-17
score: 62.5
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 129..144
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 90..103
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 105..129
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 637..891
score: 21.353

Blast
BLAST of TCONS_00004075-protein vs. Swiss-Prot (Human)
Match: AGRL3 (Adhesion G protein-coupled receptor L3 OS=Homo sapiens GN=ADGRL3 PE=1 SV=2)

HSP 1 Score: 103.605 bits (257), Expect = 2.742e-22
Identity = 72/292 (24.66%), Postives = 138/292 (47.26%), Query Frame = 0
Query:  610 CVCQTMAHYLIVYNYTNVKPVAQAVKEDVYNVLIYISYGINCFCIIWSLLIH-FYHKTNQASILLHSNLSFVILCTETIYVFGIS-TDINFDKVHCKWIIVVFQFFLASLFTWFLTLSWQSYHRLNDVIKQTYRRRRGTYILFGYGYAVLLTLISMAIFYKDFGNLSHGMCWMS-RTILISVFIPPIALLIMFCVVMLGMVIGIYFSPRSSQSLPDSKTMELEKEEIYSVRDNVRATAIMLPICMLTWLFAILRVTENDDFTKYMFFFFNTIQGIAFLTVYCFLNKELAQYY 898
            C C  + ++ ++  +  VK  + AV + + +V+ ++   ++  C++  +    F+         +H NL   +   E +++ GI+ TD     + C     +  FF  + FTW      Q Y  L +V +  + RR+  Y L GYG   L+  +S A+ Y+ +G  +  +CW+   T  I  FI P  L+IM  V+ LG+ +   F   ++   P+S  ++       +++  V     +L +  LTW F ++ + E+     Y+F  FN++QG+     +C L K++ + Y
Sbjct:  836 CSCNHLTNFAVLMAHVEVK-HSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTD---QPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFY-LVGYGMPALIVAVSAAVDYRSYG--TDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFH-HTAILKPESGCLD-------NIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEY 1112          
The following BLAST results are available for this feature:
BLAST of TCONS_00004075-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
AGRL32.742e-2224.66Adhesion G protein-coupled receptor L3 OS=Homo sap... [more]
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