TCONS_00004305-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004305-protein
Unique NameTCONS_00004305-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length764

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004305-protein ID=TCONS_00004305-protein|Name=TCONS_00004305-protein|organism=Clytia hemisphaerica|type=polypeptide|length=764bp
MPRKTTIACCSLSQWALDFEGNLRRILESIRLAKEIGARYRVGPELEISG
YGCNDHFLESDTFLHSWESLACILENSVCENILVDVGMPVLRNQVTYNCR
VIIYNKKILLVRPKMRLARDGNYREHRWFTAWTKKMELEDIRLPPLINKI
TGQSKAPFGDALLVTVDSVIGYETCQELFEIHTSHSDLALSGAEIVFNSS
GSHHELRKLSQRIKLISDGLNKTGGVYVYSNLKGCDGERVYYDGASMIFI
NSELVGQSNQFSLDEVEMISAVVDLDDIYAARNGVSFGSEVESQKKRYPK
VATDIILCHHDGLTMPTSRVIPATIHRPEEEIALGPACWLWDYLRRSGCN
GFFLPLSGGVDSSATACIVASMCRLVCQSVKRGNAQTLSDTRKMVNDQTY
VPKDPNELCGRIFVTCYMGTENSSVDTQARARNLASDIGSYHLGIFIDTA
IKALIGIFTTVTGKTPKFRFYGGTNTENLALQNIQARTRMVLSYLFAQLT
LWSRGSPGSLLVLGSANVDESLLGYMTKYDCSSADLNPIGGISKNDLKKF
IFYCVEKYNFTSLIGILGAPPTAELEPLKDGQLQQTDEQDMGLTYDELSL
FGRLRKVDRCGPYSMFTKLLNLWHSVCPNDIADKVKTFFKKYAINRHKMT
TVTPSYHAEAYSPDDNRFDMRPFLYRTSWPWQFRSIDRAVATANKSIITQ
SSRKTPDLTCNERDDASSVGSDTTSASMVYRLSSFSSSSLQRDHPDTGFD
SDLPKKRIKVEVDE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002388XLOC_002388Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004305TCONS_00004305Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003010C-N_Hydrolase
IPR014729Rossmann-like_a/b/a_fold
IPR014445Gln-dep_NAD_synthase
IPR022310NAD/GMP_synthase
IPR003694NAD_synthase
Vocabulary: Molecular Function
TermDefinition
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0003952NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006807nitrogen compound metabolic process
GO:0009435NAD biosynthetic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0009435 NAD biosynthetic process
biological_process GO:0006807 nitrogen compound metabolic process
molecular_function GO:0005524 ATP binding
molecular_function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
molecular_function GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003010Carbon-nitrogen hydrolaseGENE3D3.60.110.10coord: 1..289
e-value: 7.3E-45
score: 152.5
IPR003010Carbon-nitrogen hydrolasePFAMPF00795CN_hydrolasecoord: 6..282
e-value: 1.7E-30
score: 106.1
IPR003010Carbon-nitrogen hydrolasePROSITEPS50263CN_HYDROLASEcoord: 5..300
score: 16.905
IPR003010Carbon-nitrogen hydrolaseSUPERFAMILY56317Carbon-nitrogen hydrolasecoord: 3..286
IPR014729Rossmann-like alpha/beta/alpha sandwich foldGENE3D3.40.50.620coord: 330..676
e-value: 9.1E-69
score: 231.4
IPR014445Glutamine-dependent NAD(+) synthetasePIRSFPIRSF006630NADS_GATcoord: 2..683
e-value: 2.0E-147
score: 489.9
IPR022310NAD/GMP synthasePFAMPF02540NAD_synthasecoord: 339..598
e-value: 1.9E-23
score: 82.7
IPR003694NAD(+) synthetaseTIGRFAMTIGR00552TIGR00552coord: 474..649
e-value: 4.0E-19
score: 66.8
IPR003694NAD(+) synthetaseCDDcd00553NAD_synthasecoord: 328..649
e-value: 3.57398E-78
score: 252.468
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 701..724
NoneNo IPR availableCDDcd07570GAT_Gln-NAD-synthcoord: 6..294
e-value: 4.19737E-80
score: 258.168
NoneNo IPR availableSUPERFAMILY52402Adenine nucleotide alpha hydrolases-likecoord: 319..378
coord: 405..661

Blast
BLAST of TCONS_00004305-protein vs. Swiss-Prot (Human)
Match: NADE (Glutamine-dependent NAD(+) synthetase OS=Homo sapiens GN=NADSYN1 PE=1 SV=3)

HSP 1 Score: 891.338 bits (2302), Expect = 0.000e+0
Identity = 409/691 (59.19%), Postives = 527/691 (76.27%), Query Frame = 0
Query:    1 MPRKTTIACCSLSQWALDFEGNLRRILESIRLAKEIGARYRVGPELEISGYGCNDHFLESDTFLHSWESLACILENSVCENILVDVGMPVLRNQVTYNCRVIIYNKKILLVRPKMRLARDGNYREHRWFTAWTKKMELEDIRLPPLINKITGQSKAPFGDALLVTVDSVIGYETCQELFEIHTSHSDLALSGAEIVFNSSGSHHELRKLSQRIKLISDGLNKTGGVYVYSNLKGCDGERVYYDGASMIFINSELVGQSNQFSLDEVEMISAVVDLDDIYAARNGVSFGSEVESQKKRYPKVATDIILCHHDGLTMPTSRVIPATIHRPEEEIALGPACWLWDYLRRSGCNGFFLPLSGGVDSSATACIVASMCRLVCQSVKRGNAQTLSDTRKMVNDQTYVPKDPNELCGRIFVTCYMGTENSSVDTQARARNLASDIGSYHLGIFIDTAIKALIGIFTTVTGKTPKFRFYGGTNTENLALQNIQARTRMVLSYLFAQLTLWSRGSPGSLLVLGSANVDESLLGYMTKYDCSSADLNPIGGISKNDLKKFIFYCVEKYNFTSLIGILGAPPTAELEPLKDGQLQQTDEQDMGLTYDELSLFGRLRKVDRCGPYSMFTKLLNLWHSVC-PNDIADKVKTFFKKYAINRHKMTTVTPSYHAEAYSPDDNRFDMRPFLYRTSWPWQFRSIDRAV 690
            M RK T+A C+L+QWALDFEGNL+RIL+SI +AK  GARYR+GPELEI GYGC DH+ ESDT LHS++ LA ++E+ V ++I+ DVGMPV+   V YNCRVI  N+KILL+RPKM LA +GNYRE RWFT W++    E+  LP +I  +T Q   PFGDA+LVT D+ IG E C+EL+  H+ H D+ L G EI+ N+SGSH  LRK + R+ L++   +K GG+Y+ +N KGCDG+R+YYDG +MI +N  +  Q +QFSLD+VE+++A +DL+D+ + R  +S  +   S+   YP+V  D  L  H+ L  P S  I    H PEEEI+LGPACWLWD+LRRS   GF LPLSGGVDS+ATAC++ SMC  VC++V+ GN + L+D R +VN  +Y P+DP +LCGRI  TCYM ++NSS +T  RAR LA  IGS+H+ + ID A+KA++GIF+ VTGK+P F  +GG++ ENLALQN+QAR RMVL+YLFAQL+LWSRG  G LLVLGSANVDESLLGY+TKYDCSSAD+NPIGGISK DL+ F+ +C++++   +L  IL AP TAELEPL DGQ+ QTDE+DMG+TY ELS++G+LRKV + GPYSMF KLL +W  +C P  +ADKVK FF KY++NRHKMTT+TP+YHAE YSP+DNRFD+RPFLY TSWPWQFR I+  V
Sbjct:    1 MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALVESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGVDSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQV 691          
The following BLAST results are available for this feature:
BLAST of TCONS_00004305-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NADE0.000e+059.19Glutamine-dependent NAD(+) synthetase OS=Homo sapi... [more]
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