TCONS_00004372-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004372-protein
Unique NameTCONS_00004372-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length476

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004372-protein ID=TCONS_00004372-protein|Name=TCONS_00004372-protein|organism=Clytia hemisphaerica|type=polypeptide|length=476bp
MIFLICSIKLVVILMFLRFSTASKVNSEMKLVDYILANYSKQARPVINPR
HSINVTFGIEIVHLIKVDDRNQMLTTKIWVRQQWLNELLKWDSSKWSGTT
EVQIDGQLVWVPDIVLYNNADSEFSGGVEKYKTRIIQYSDGTSFWLAPAT
FTSTCSIDIKYFPFDKQECHLKFGSWTFDIAGINLLKDNRPLITDQYSAS
SEWDLIKAEKLRHVVKYQCCPEPYVDITFNLVLLRKPLYFVFNVIAPCLV
LVMTVFFGFFLPPESGERISLTITILLAVAVFLQLISDALPRNSNSVPML
AVFYMAIMAESAFSLITTCIVLVIHYRSSERGAAPMPKWVRSFFLGTCAK
FFGIHGYYDELETMQTETRLGEDANKNHSSAYDNGFYMSDEYNDLQKSNP
NSTLQTNNFSGTLDVILKEIQIITKGMLSSHQKSELQEDWRLLARVLDRL
FFWLFLVTVVSSALGILVPVYLIHHG
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002446XLOC_002446Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004372TCONS_00004372Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR002394Nicotinic_acetylcholine_rcpt
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO:0045211postsynaptic membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0022848acetylcholine-gated cation-selective channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0045211 postsynaptic membrane
molecular_function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 108..119
score: 50.68
coord: 155..169
score: 51.31
coord: 231..243
score: 34.67
coord: 75..91
score: 34.31
IPR006201Neurotransmitter-gated ion-channelTIGRFAMTIGR00860TIGR00860coord: 14..467
e-value: 2.1E-89
score: 298.3
IPR002394Nicotinic acetylcholine receptorPRINTSPR00254NICOTINICRcoord: 62..78
score: 37.84
coord: 114..126
score: 58.21
coord: 96..110
score: 19.11
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 29..237
e-value: 1.8E-57
score: 194.1
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 18..241
e-value: 7.8E-67
score: 224.5
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 26..237
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 244..466
e-value: 2.2E-37
score: 129.3
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 237..469
NoneNo IPR availableGENE3D1.20.58.390coord: 242..475
e-value: 1.8E-40
score: 137.6
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 155..169

Blast
[Close]
BLAST of TCONS_00004372-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 277.33 bits (708), Expect = 8.490e-88
Identity = 152/479 (31.73%), Postives = 259/479 (54.07%), Query Frame = 0 
Query:   22 ASKVNSEMKLVDYILANYSKQARPVINPRHSINVTFGIEIVHLIKVDDRNQMLTTKIWVRQQWLNELLKWDSSKWSGTTEVQIDGQLVWVPDIVLYNNADSEFSGGVEKYKTRIIQYSDGTSFWLAPATFTSTCSIDIKYFPFDKQECHLKFGSWTFDIAGINLLKDNRPLITDQYSASSEWDLIKAEKLRHVVKYQCCPEPYVDITFNLVLLRKPLYFVFNVIAPCLVLVMTVFFGFFLPPESGERISLTITILLAVAVFLQLISDALPRNSNSVPMLAVFYMAIMAESAFSLITTCIVLVIHYRSSERGAAPMPKWVRSFFL----------------GTCAKFFGIHGYYDELETMQTETRLGEDANKNHSSAYDNGFYMSDEYNDLQKSNPNSTLQTNNFSGTLDVIL-------------KEIQIITKGMLSSHQKSELQEDWRLLARVLDRLFFWLF-LVTVVSSALGILVPV 470
            A    +E +L + +  +Y++  RPV N    + + F + +  L+KVD+ NQ++ T +W++Q W +  LKW+ S + G   +++  Q +W PDIVLYNNA  +F   V+     +++Y+ G   W+ PA F S+C ID+ YFPFD Q C +KFGSW++D A I+L+     +    Y  S EW +IKA   +H +KY CC E Y DIT++L + R PL++  N+I PCL++       F+LP + GE+++L I++LL++ VFL +I++ +P  S  +P++  + +  M     S++ T  VL +HYR+       MP WV++ FL                G   K   ++G   EL  +   +R      K      D G      +  ++ SN ++ L  ++ S ++D +L             + ++ I + M + ++  E+Q+DW+ +A V+DR+F W+F LV ++ +A   L P+
Sbjct:   29 ARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ--VDDKTKALLKYT-GEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHT--MPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYG--AELSNLNCFSRAESKGCKEGYPCQD-GMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQPL 499
The following BLAST results are available for this feature:
BLAST of TCONS_00004372-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA38.490e-8831.73Neuronal acetylcholine receptor subunit alpha-3 OS... [more]
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