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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00004921-protein ID=TCONS_00004921-protein|Name=TCONS_00004921-protein|organism=Clytia hemisphaerica|type=polypeptide|length=957bp
MEIQSLSLNGQVAPPSKHKTHTFKKKTFNKPTYCQHCTDLLWGLTNQGVQ
CLDCKYISHDRCRQKVVTPCQRSGANDNNNEDNCIEDQSECRSEITGHLF
KRKTFHKPTYCHYCSDLLWGLKNQGLQCNDCGYATHERCQLQITTLCNFK
ALRQVQHPKFHSFVKSEMDKKRFCNVCRKAVNDNDLSCQACYYYTHEGCR
NRIIHNCKRTSTYSHAVAQLKVKQQHHWSEGHLPNNSKCSACNNACSSND
CLYGLRCTWCATTVHSYCVGRMTEACNFGILRSVLLPPYAVKENNPKCFL
PPPSLEQPENSPLTSPERKSSRTDQFQLRVHEGPVDRPVLWREITINKKS
TTKDVLSDICNTFNCKEQKTLFYLTIVHKNGVETKLSNGDILTRKVDVAN
AETKQVFLRHTNLGDKELKITLYAKNIDTSLPSVQMNVNIMVEAKEIVTQ
AVKLFQLSDTAEANGAHYCITQMKIAPNSVTESPINDTDSLFQVLIGKPA
QQGRKEAVGEFHSTRFYLCPREPNTFEALLFVGKLPNDLSPLHYKNLLTD
IIGKWDSQSMTMEHTFPVHGAVIIRFKSMASFQRTFTCLQSAKVEEKSVF
LKVLPEIKEDMLASNSNPLLLFVNSKSGGGQGAKLMSKFSRMLNPHQIID
LLAEGPLPALYTFRNLRRFRILICGGDGTFGWVLNVLDDIRHQVLKCEEP
PSACLPLGTGNDLARVLNWGGGYTGSETCLNVLMNVMTATETMLDRWNLV
FDSSSFSENNSSDNINMLPMNNYFSVGIDAAICLEFHLSREENPEKFNNR
FHNKGVYVKASLKNMSKSNMANLDERMELCVDGVDVPLPNIEGLCVLNIG
SWGAGADCWGKDQDGRFKAQSFGDGLLEVVGFTGVYHMGKIQGGVSTAVR
IAQGSQINLLLREDVPVQVDGEPWMQPASLVIIRPNPFSQARMLMKAQQV
RSITNAS Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0016301 | kinase activity |
| GO:0004143 | diacylglycerol kinase activity |
| GO:0003951 | NAD+ kinase activity |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
| GO:0035556 | intracellular signal transduction |
| GO:0008152 | metabolic process |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0008152 |
metabolic process |
| biological_process |
GO:0007205 |
protein kinase C-activating G-protein coupled receptor signaling pathway |
| molecular_function |
GO:0004143 |
diacylglycerol kinase activity |
| molecular_function |
GO:0016301 |
kinase activity |
| molecular_function |
GO:0003951 |
NAD+ kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR020454 | Diacylglycerol/phorbol-ester binding | PRINTS | PR00008 | DAGPEDOMAIN | coord: 34..43
score: 53.37
coord: 18..32
score: 36.77
coord: 124..135
score: 43.48
coord: 136..148
score: 32.14 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | SMART | SM00046 | dagk_c4a_7 | coord: 618..747
e-value: 3.0E-47
score: 173.0 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | PFAM | PF00781 | DAGK_cat | coord: 618..732
e-value: 4.2E-23
score: 81.2 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | PROSITE | PS50146 | DAGK | coord: 614..753
score: 36.991 |
| IPR000756 | Diacylglycerol kinase, accessory domain | SMART | SM00045 | dagk_c4b_2 | coord: 769..923
e-value: 2.8E-67
score: 239.5 |
| IPR000756 | Diacylglycerol kinase, accessory domain | PFAM | PF00609 | DAGK_acc | coord: 770..923
e-value: 1.9E-52
score: 177.7 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 161..207
e-value: 0.025
score: 20.9
coord: 226..276
e-value: 1.6E-5
score: 34.4
coord: 98..147
e-value: 1.5E-13
score: 61.0
coord: 21..70
e-value: 1.4E-13
score: 61.2 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 226..277
e-value: 1.3E-7
score: 31.2
coord: 98..148
e-value: 5.3E-12
score: 45.3
coord: 21..71
e-value: 1.5E-13
score: 50.3 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 226..276 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 98..147 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 21..70 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 225..276
score: 10.794 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 20..70
score: 15.246 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 97..147
score: 15.266 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 160..207
score: 10.493 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 226..276
e-value: 9.04096E-7
score: 46.3312 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 98..147
e-value: 1.40146E-13
score: 65.9763 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 29..70
e-value: 8.22366E-10
score: 55.1908 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 19..86
e-value: 3.0E-19
score: 68.1 |
| None | No IPR available | GENE3D | 3.10.20.90 | | coord: 418..522
e-value: 0.001
score: 19.2 |
| None | No IPR available | GENE3D | 3.10.20.90 | | coord: 306..417
e-value: 6.3E-6
score: 25.9 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 95..152
e-value: 8.5E-17
score: 60.3 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 224..277
e-value: 4.7E-11
score: 42.1 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 153..209
e-value: 5.6E-7
score: 28.9 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1..21 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 300..325 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 94..151 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 155..209 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 18..71 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 219..281 |
| IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, domain 1 | GENE3D | 3.40.50.10330 | | coord: 601..747
e-value: 4.9E-30
score: 103.2 |
| IPR029071 | Ubiquitin-related domain | SUPERFAMILY | 54236 | Ubiquitin-like | coord: 325..388 |
| IPR016064 | NAD kinase/diacylglycerol kinase-like domain | SUPERFAMILY | 111331 | NAD kinase/diacylglycerol kinase-like | coord: 616..936 |
Blast
BLAST of TCONS_00004921-protein vs. Swiss-Prot (Human)
Match: DGKQ (Diacylglycerol kinase theta OS=Homo sapiens GN=DGKQ PE=1 SV=2) HSP 1 Score: 520.39 bits (1339), Expect = 5.167e-170 Identity = 308/881 (34.96%), Postives = 462/881 (52.44%), Query Frame = 0
Query: 97 GHLFKRKTFHKPTYCHYCSDLLWGLKNQGLQCNDCGYATHERCQLQITTLCNFKALRQVQHPKFHSFVKSEMDKKRFCNVCRKAVNDNDLSCQACYYYTHEGCRNRIIHNCKRTSTYSHAVAQLKVKQQHHWSEGHLPNNSKCSACNNACSSNDCLYGLRCTWCATTVHSYCVGRMTEACNFGILRSVLLPPYAVKE-----NNPKCFL------PPPSLEQPENSPLTSPERKSSRTDQF---QLRVHEGP-VDRPVLWREITINKKSTTKDVLSDICNTFNCKEQKTLFYLTIVHKNGVETKLSNGD-----ILT---RKVDVANAETKQVFLRHTNLGDKELKITLYAKNIDTSLPSVQMNVNIMVEAKEIVTQAVKLFQLSDTAEANGAHYCITQMKIAPNSVTESPINDTDSLFQVLIGKPAQQGRKEAVGEFHSTRFYLCPREPNTFEALLFVGKLPNDLSPLHYKNLLTDIIGKWDSQSMTMEHTFPVHGAVIIRFKSMASFQRTFTCLQSAKVEEKSVFLKVLPEIKEDMLASNSNPLLLFVNSKSGGGQGAKLMSKFSRMLNPHQIIDLLAEGPLPALYTFRNLRRFRILICGGDGTFGWVLNVLDDIRHQVLKCEEPPSACLPLGTGNDLARVLNWGGGYTGSETCLNVLMNVMTATETMLDRWNLVFDS--SSFSENNSSDN--INMLPMNNYFSVGIDAAICLEFHLSREENPEKFNNRFHNKGVYVKASLKNMSKSNMANLDERMELCVDGVDVPLPNIEGLCVLNIGSWGAGADCWGKDQDGRFKAQSFGDGLLEVVGFTGVYHMGKIQGGVSTAVRIAQGSQINLLLREDVPVQVDGEPWMQ-PASLVIIRPNPFSQARMLMKAQQ 949
GH F++ T KPT+CH CSD +WGL G C+ C + +HE+C + C A V+ P H F + K++FC VCRK + L C+ C + H C +C++ Q HHW EG+LP+ ++C C C S+D L G+RC WC HS C + C FG LRS++LPP V+ + + F P + + S P R++ T + L++ +G R +R +T+++ + ++VL + E L + + G +++ R A + +R + LKI Y + + V + V A+ +V + + L L AE+ + + + ++ + V + + D L L Q R+ +V + TRFY+ LFVG LP LSP Y +LL + G + +++ H + GAV++ A +R + L+ V + + VLP++ L +S PLL+FVN KSGG +G L+ F ++LNPHQ+ DL GPLP L+ F + FR+L+CGGDGT GWVL L++ R++ L C EP A LPLGTGNDL RVL WG GY+G E +VL++V A ++DRW ++ D+ + +EN+++D ++ M+NY +GIDA + L+FH +REE P KF +R HNKGVYV+ L+ +S S +L +++ L V+ +V LP+IEGL +NI SWG+GAD WG D D RF+ DGLLEVVG TGV HMG++QGG+ + +RIAQGS + L + PVQVDGEPW+Q P ++I P + ML KA+Q
Sbjct: 60 GHSFRKVTLTKPTFCHLCSDFIWGLA--GFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPVAHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCH---QDGHQDHDTHHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLRSLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTLKIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAWAGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKI--YPGWLKVGVAYVSVRVTPKSTARSVVLEVLPL--LGRQAESPES-FQLVEVAMGCRHVQRTMLMDEQPLLDRL-----QDIRQMSVRQVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEA-GATKATVVSVSHIYSSQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEETRYR-LACPEPSVAILPLGTGNDLGRVLRWGAGYSG-EDPFSVLLSVDEADAVLMDRWTILLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRVGLQKISHSR--SLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKPRMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGHMIISAAGP--KVHMLRKAKQ 918
The following BLAST results are available for this feature:
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