TCONS_00005439-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00005439-protein
Unique NameTCONS_00005439-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length444

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00005439-protein ID=TCONS_00005439-protein|Name=TCONS_00005439-protein|organism=Clytia hemisphaerica|type=polypeptide|length=444bp
KKYDLIMDIRGETQKYKKNKKLKVKNSKFHVENTPYNYPLFTKNSLNFEK
QHNMDASLKRRSPSLDEVQPKRSRSNVDERELTQSCVAGSRKSPLAVTQT
NTIVAALKKIHPDYDFPIETMQTLGDRILHLALPKIGQKGLFTKDLENAL
NEKRVDFLVHSLKDLPTKMPEGMALGCVFKRDNPFDCVIFHSKHVGKKLE
DLAPNSVIGTSSLRRVAQLKRKYPTLIFQSVRGNLNTRLRKLEEDGVYDA
IILAKAGIDRMNWTEKIGQILEEEIAYAVGQGAMAVEIRDDDQFMMKVLS
KITDMKTMLTVIAERAFMRKLDGGCSTPVGCNVTYEDGMLHLRGVCLSVD
GKDCVEDRMSAPINFDLPRPEGEKEKTFFVSDVGVVVDTLYKNEYEKATK
LGDDVATKLIELGADEILKTVKLAIPNVANIQLPVANSGTMKFV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003098XLOC_003098Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00005439TCONS_00005439Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000860HemC
IPR022418Porphobilinogen_deaminase_C
IPR022417Porphobilin_deaminase_N
IPR022419Porphobilin_deaminase_cofac_BS
Vocabulary: Molecular Function
TermDefinition
GO:0004418hydroxymethylbilane synthase activity
Vocabulary: Biological Process
TermDefinition
GO:0033014tetrapyrrole biosynthetic process
GO:0018160peptidyl-pyrromethane cofactor linkage
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0018160 peptidyl-pyrromethane cofactor linkage
biological_process GO:0033014 tetrapyrrole biosynthetic process
molecular_function GO:0004418 hydroxymethylbilane synthase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000860Porphobilinogen deaminasePRINTSPR00151PORPHBDMNASEcoord: 207..224
score: 64.02
coord: 156..175
score: 52.62
coord: 313..330
score: 56.88
coord: 125..145
score: 56.24
coord: 226..243
score: 58.47
IPR000860Porphobilinogen deaminaseTIGRFAMTIGR00212TIGR00212coord: 88..361
e-value: 7.5E-92
score: 305.4
NoneNo IPR availableGENE3D3.40.190.10coord: 188..282
e-value: 5.9E-29
score: 99.6
NoneNo IPR availableGENE3D3.40.190.10coord: 76..187
e-value: 2.7E-38
score: 129.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 56..81
NoneNo IPR availableCDDcd13645PBP2_HuPBGD_likecoord: 89..363
e-value: 5.35122E-136
score: 394.296
NoneNo IPR availableSUPERFAMILY53850Periplasmic binding protein-like IIcoord: 87..301
IPR022418Porphobilinogen deaminase, C-terminalPFAMPF03900Porphobil_deamCcoord: 309..363
e-value: 1.8E-14
score: 53.7
IPR022418Porphobilinogen deaminase, C-terminalGENE3D3.30.160.40coord: 304..421
e-value: 5.9E-23
score: 80.6
IPR022418Porphobilinogen deaminase, C-terminalSUPERFAMILY54782Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domaincoord: 304..363
IPR022417Porphobilinogen deaminase, N-terminalPFAMPF01379Porphobil_deamcoord: 89..295
e-value: 1.2E-68
score: 230.6
IPR022419Porphobilinogen deaminase, dipyrromethane cofactor binding sitePROSITEPS00533PORPHOBILINOGEN_DEAMcoord: 314..330

Blast
[Close]
BLAST of TCONS_00005439-protein vs. Swiss-Prot (Human)
Match: HEM3 (Porphobilinogen deaminase OS=Homo sapiens GN=HMBS PE=1 SV=2)

HSP 1 Score: 317.005 bits (811), Expect = 1.579e-105
Identity = 163/335 (48.66%), Postives = 217/335 (64.78%), Query Frame = 0 
Query:   89 GSRKSPLAVTQTNTIVAALKKIHPDYDFPIETMQTLGDRILHLALPKIGQKGLFTKDLENALNEKRVDFLVHSLKDLPTKMPEGMALGCVFKRDNPFDCVIFHSKHVGKKLEDLAPNSVIGTSSLRRVAQLKRKYPTLIFQSVRGNLNTRLRKLEEDGVYDAIILAKAGIDRMNWTEKIGQILE-EEIAYAVGQGAMAVEIRDDDQFMMKVLSKITDMKTMLTVIAERAFMRKLDGGCSTPVGCNVTYEDGMLHLRGVCLSVDGKDCVEDRMSAPINFDLPRPEGEKEKTFFVSDVGVVVDTLYKNEYEKATKLGDDVATKLIELGADEILKTVK 422
            G+RKS LA  QT+++VA LK  +P   F I  M T GD+IL  AL KIG+K LFTK+LE+AL +  VD +VHSLKDLPT +P G  +G + KR+NP D V+FH K VGK LE L   SV+GTSSLRR AQL+RK+P L F+S+RGNLNTRLRKL+E   + AIILA AG+ RM W  ++GQIL  EE  YAVGQGA+ VE+R  DQ ++ ++  + D +T+L  IAERAF+R L+GGCS PV  +   +DG L+L G   S+DG D +++ M A I+      +G ++       VG+    + +     A  LG  +A  L+  GA  IL   +
Sbjct:   24 GTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQL---VGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVAR 355
The following BLAST results are available for this feature:
BLAST of TCONS_00005439-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HEM31.579e-10548.66Porphobilinogen deaminase OS=Homo sapiens GN=HMBS ... [more]
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