TCONS_00005840-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00005840-protein
Unique NameTCONS_00005840-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1154

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00005840-protein ID=TCONS_00005840-protein|Name=TCONS_00005840-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1154bp
MASKGSPITSSNYQQKLESIKENGIINEVANDPEDREDVFQTDAESETKS
TSSSESSASNIVETSTMNRKKSVLKRGGGEQRTKPLLQKRVSFSSVPSER
RRRVSSAADCFTYMQSGTEFLKLRPGGRQYQRFYQLDQDMLLLHWRPSSK
KPEKAILPVDLLYEIRTGKNTTVFKEQGMSYNEDCCFSLIVGPNYDSIDL
VATSSDEANIWITGLRLLNQKSGMLYVRSGSVGSQDSVDGNTPEEDDQQK
DVDMRERWLRQQFRLADKEHIGYINDKALFTLLKKLRTNAPQQMVKQKFK
EYATHSSLEGGTYISEDDFYQLFIDLTTRQEIYFLLVKYSSNGLFMTTDD
LLLFLETEQGITWAGKEYSLEIINRCEPSEECRKKQVLGLDGLTKYFSEK
DCHIFEPNHFNVCEDMKKPLSHYFIASSHNTYLLDDQLRGRSSIQGYINC
LQQGCRCVELDCWDGPNNEPIIYHGHTLTTKILFLDVILTIREYAFLTSD
YPLILSIENHCSVKQQEVMAQHLKKVFAETLYKTPANESLSYLPSPESLK
GKVIVKNKKLPRSSSGSTSELGDVSEEEEEGRRTVTSHFADMTSSQQNGS
PSTNQSEGNVNDTGAFENVDNCCAEEDDEVYIKTKSPQKFGRSMSTDANL
SQSGKLMKLAPDLSDLVNLCKSVRFQSFQHSFERQKYWEICSIGETTGRK
LCQTCPEEFVSYTKKFLSRIYPAAKRVDSSNYNPVEFWNCGCQLVSLNYQ
YSGLAMDLNRGRFLKNGQCGYALKPGVMRDEVAYFSPTMKHEIPGVSPLT
LQIKIISGTQLPKPRGSTSKGDALDPYVMVELYGLAADCHYERSRTIPHN
GYNPVFDETFEFRVILPELALLRFVVLDDDHIGDCFIGQCTIPLECIRQG
YRTVYLLSATGEDLAPASLFVHVSFLREDEITVKNKGFSIAKSLRKKEFT
SLRSLGMKVIDDTFKLSINPLREATTLRENYQNSLNNFKDCCGLTPRNNI
KQCMRILLNRIQTAIEATPTLKCSIDISKEFPSVYSEGEIPPIVNKALNA
FEQLVSESQTISNLTGDVYERLTHARRSAFEWHGDLRKKCQQENFKDRRT
NKVIENFSWNIKILCGQADLLKTTKQRCDESLKQIKDVIRVSQTTSNENK
EAGT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003332XLOC_003332Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00005840TCONS_00005840Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001192PI-PLC_fam
IPR001711PLipase_C_Pinositol-sp_Y
IPR000008C2_dom
IPR000909PLipase_C_PInositol-sp_X_dom
IPR001849PH_domain
IPR011993PH_dom-like
IPR017946PLC-like_Pdiesterase_TIM-brl
IPR015359PLC_EF-hand-like
IPR011992EF-hand-dom_pair
Vocabulary: Biological Process
TermDefinition
GO:0035556intracellular signal transduction
GO:0007165signal transduction
GO:0006629lipid metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0004435phosphatidylinositol phospholipase C activity
GO:0008081phosphoric diester hydrolase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0006629 lipid metabolic process
biological_process GO:0007165 signal transduction
molecular_function GO:0004435 phosphatidylinositol phospholipase C activity
molecular_function GO:0008081 phosphoric diester hydrolase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001192Phosphoinositide phospholipase C familyPRINTSPR00390PHPHLIPASECcoord: 738..756
score: 49.85
coord: 445..465
score: 56.06
coord: 542..559
score: 53.25
coord: 717..738
score: 60.12
coord: 892..902
score: 43.91
coord: 419..437
score: 70.71
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainSMARTSM00149plcy_3coord: 663..779
e-value: 9.1E-58
score: 207.9
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainPFAMPF00387PI-PLC-Ycoord: 663..775
e-value: 3.9E-38
score: 130.2
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domainPROSITEPS50008PIPLC_Y_DOMAINcoord: 663..779
score: 46.697
IPR000008C2 domainSMARTSM00239C2_3ccoord: 800..906
e-value: 1.4E-21
score: 87.7
IPR000008C2 domainGENE3D2.60.40.150coord: 791..927
e-value: 3.6E-24
score: 84.6
IPR000008C2 domainPFAMPF00168C2coord: 800..901
e-value: 6.2E-16
score: 58.5
IPR000008C2 domainPROSITEPS50004C2coord: 786..891
score: 18.804
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 800..925
IPR000909Phosphatidylinositol-specific phospholipase C, X domainSMARTSM00148plcx_3coord: 414..558
e-value: 8.1E-84
score: 294.4
IPR000909Phosphatidylinositol-specific phospholipase C, X domainPFAMPF00388PI-PLC-Xcoord: 416..559
e-value: 1.5E-63
score: 212.6
IPR000909Phosphatidylinositol-specific phospholipase C, X domainPROSITEPS50007PIPLC_X_DOMAINcoord: 414..558
score: 58.213
IPR001849Pleckstrin homology domainPFAMPF16457PH_12coord: 109..218
e-value: 5.8E-10
score: 39.7
IPR011993PH domain-likeGENE3D2.30.29.30coord: 117..221
e-value: 2.6E-20
score: 72.2
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 108..218
NoneNo IPR availableGENE3D1.10.238.10coord: 231..323
e-value: 1.8E-5
score: 24.2
NoneNo IPR availableGENE3D1.10.238.10coord: 324..410
e-value: 1.3E-13
score: 50.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 560..611
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 24..81
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 232..251
NoneNo IPR availableCDDcd00275C2_PLC_likecoord: 798..925
e-value: 2.99598E-53
score: 182.356
IPR017946PLC-like phosphodiesterase, TIM beta/alpha-barrel domainGENE3D3.20.20.190coord: 411..790
e-value: 1.4E-136
score: 454.4
IPR017946PLC-like phosphodiesterase, TIM beta/alpha-barrel domainSUPERFAMILY51695PLC-like phosphodiesterasescoord: 607..780
coord: 414..580
IPR015359Phosphoinositide-specific phospholipase C, EF-hand-like domainPFAMPF09279EF-hand_likecoord: 325..407
e-value: 1.0E-14
score: 54.7
IPR011992EF-hand domain pairSUPERFAMILY47473EF-handcoord: 254..413

Blast
BLAST of TCONS_00005840-protein vs. Swiss-Prot (Human)
Match: PLCL2 (Inactive phospholipase C-like protein 2 OS=Homo sapiens GN=PLCL2 PE=1 SV=2)

HSP 1 Score: 926.006 bits (2392), Expect = 0.000e+0
Identity = 477/1072 (44.50%), Postives = 682/1072 (63.62%), Query Frame = 0
Query:   67 MNRKKSVLKRGGGEQRTKPLLQKRVSFSSVPSERRRRVSSAADCFTYMQSGTEFLKLRPGGRQYQRFYQLDQDMLLLHWRPSSKKPEKAILPVDLLYEIRTGKNTTVFKEQGMS--YNEDCCFSLIVGPNYDSIDLVATSSDEANIWITGLRLLNQKSGMLYVRSGSVGSQDSVDGNTPEEDDQQKDVDMRERWLRQQFRLADKEHIGYINDKALFTLLKKLRTNAPQQMVKQKFKEYATHSSLEGGTYISEDDFYQLFIDLTTRQEIYFLLVKYSSNGLFMTTDDLLLFLETEQGITWAGKEYSLEIINRCEPSEECRKKQVLGLDGLTKYFSEKDCHIFEPNHFNVCEDMKKPLSHYFIASSHNTYLLDDQLRGRSSIQGYINCLQQGCRCVELDCWDGPNNEPIIYHGHTLTTKILFLDVILTIREYAFLTSDYPLILSIENHCSVKQQEVMAQHLKKVFAETLYKTPANESLSYLPSPESLKGKVIVKNKKLPRSSSGSTSELGDVSEEEEEGRRTVTSHFADMTSSQQNGSPSTNQSEGNVNDTGAFENVDNCCAEEDDEVYIKTKSPQKFGRSMSTDANLSQSGKLMKLAPDLSDLVNLCKSVRFQSFQHSFERQKYWEICSIGETTGRKLCQTCPEEFVSYTKKFLSRIYPAAKRVDSSNYNPVEFWNCGCQLVSLNYQYSGLAMDLNRGRFLKNGQCGYALKPGVMRDEVAYFSPTMKHEIPGVSPLTLQIKIISGTQLPKPRGSTSKGDALDPYVMVELYGLAADCHYERSRTIPHNGYNPVFDETFEFRVILPELALLRFVVLDDDHIGDCFIGQCTIPLECIRQGYRTVYLLSATGEDLAPASLFVHVSFL-REDEITVKNKGFSIAKSLRKKEFTSLRSLGMKVIDDTFKLSINPLREATTLRENYQNSLNNFKDCCGLTPRNNIKQCMRILLNRIQTAIEATPTLKCSIDISKEFPSVYSEGEIPPIVNKALNAFEQLVSESQTISNLTGDVYERLTHARRSAFEWHGDLRKKCQQENFKDRRTNKVIENFSWNIKILCGQADLLKTTKQRCDESLKQI 1135
            + R+ S++K G  ++R +   +K VSFSS+P+E++  +SSA+DC   M  G+E  K+R   R Y R++ LD DM  L W PS K  EKA + +  + E+RTGKNT +F+  G+S   +EDC FS+I G NY+S+DLVA S+D ANIW+TGLR L        +  G    + ++D     +D+      MR  W+ Q F   D +++G+I        ++ L        ++ KFKE    S  + GT +++++F ++F +L TR EIYFLLV++SSN  F+ T DL++FLE EQG+    +E SLEII++ EPS+E ++K  L +DG T Y    DC+IF+P H  VC+DMK+PLSHYFI SSHNTYL++DQ RG S I GYI  L+ GCR VELD WDGP+NEP+IY GHT+T++I+F  VI  I +YAF  S+YPLIL +ENHCS+KQQ+VM QH+KK+  + LY T  N   SYLPSP+ LKGK+++K KKL  + SG     GDV++E+E          A+M  SQ+ G                 EN+     E+ + V +K                        +L  +LS+LV++CKSV+F+ FQ SF+ QKYWE+CS  E    K     P +FV+Y K+FL+R++P+  R+DSSN NP +FW CGCQ+V++N+Q  GL MDLN G F +NG CGY L+P +MR+EV++FS   K  +PGVSP  L IKIISG   PKP+GS +KGD +DPYV VE++G+ ADC  +R++T+  NG  P+FDE+FEF++ LPELA++RFVVLDDD+IGD FIGQ TIP EC++ GYR V L S TGE LA ASLFVHV+   R        +G S+ K  + +E+ SLR+L +K +D+ FK +  P+R+AT LREN QN++ +FK+ CGL+   N+ QCM  +  R     + TP +   +++S+++P++  +G +P ++ K +  ++ ++   + +      VYE++ H +++A E+H  L     +E  K+R+  K +E+F+WNI IL GQADLLK  K    E+LKQI
Sbjct:  101 LPRRSSIIKDGTKQKRER---KKTVSFSSMPTEKK--ISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISDQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYL--------ISYG----KHTLDMLESSQDN------MRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHK-SKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVE---GDVTDEDEG---------AEM--SQRMGK----------------ENM-----EQPNNVPVKR----------------------FQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRF-LGPDNTPLV--VLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQI 1088          
The following BLAST results are available for this feature:
BLAST of TCONS_00005840-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PLCL20.000e+044.50Inactive phospholipase C-like protein 2 OS=Homo sa... [more]
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