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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00046703-protein ID=TCONS_00046703-protein|Name=TCONS_00046703-protein|organism=Clytia hemisphaerica|type=polypeptide|length=723bp MLKGSSGVRMLIQRVRNILQRKLPSKQLTFCMLRTLSSLATNEKQYPIEM NPLPAYIEERLKIFDEIKAEHDASMEAKEKTSIKITLPDGKQVDGFSWKT TPYEVAQGISQGLADNSVVAKVNGVLWDLDRPVEEDCTIELVKFDQPEGQ QVFWHSSAHILGEAMERHYGGCLCYGPPIEEGFYYDMSIDDRQVSSNDFS ALESVVKKIIKEKQQFVRLEMKKEDLLKMFAYNPFKLRILNERVTTPTTT VYRCGPLIDLCRGPHVRHTGKTKAIAVTKNSATYWEGKAEAESLQRIYGI SFPNDKMLKEWKHFQEEAAKRDHRKIGREQELFFFHELSPGSCFFLPNGA HIYNTLVKFIRDEYKKRGFQEVISPNIYSTKLWETSGHWQHYSTNMFSFE VEKERYALKPMNCPGHCVMFDHRPRSWRELPLRMADFGVLHRNELSGTLT GLTRVRRFQQDDAHIFCRPDQIEEEIKSCLAFLRHVYDIFGFSFKLNLST RPEKYMGDINMWNTAEKQLENSLNEFGEAWELNPGDGAFYGPKIDIQIKD ALRRYHQCATIQLDFQLPERFNLNYVTGEGDERKRPVIIHRAILGSVERM MAILTENYGGKWPFWLSPRQAIVVPVSPKYDEYAKKVADDLKASDFKAEA NLDAGETLNKKIRNAQLAHYNFILVVGDKEQSSNTVNVRTRDNKVHGEKT VEALFARFNDLMKTKKDDSEAEF Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0006435 | threonyl-tRNA aminoacylation |
GO:0043039 | tRNA aminoacylation |
GO:0006418 | tRNA aminoacylation for protein translation |
Vocabulary: Molecular Function
Term | Definition |
GO:0004829 | threonine-tRNA ligase activity |
GO:0005524 | ATP binding |
GO:0016876 | ligase activity, forming aminoacyl-tRNA and related compounds |
GO:0004812 | aminoacyl-tRNA ligase activity |
GO:0000166 | nucleotide binding |
Vocabulary: Cellular Component
Term | Definition |
GO:0005737 | cytoplasm |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0006435 |
threonyl-tRNA aminoacylation |
biological_process |
GO:0043039 |
tRNA aminoacylation |
biological_process |
GO:0006418 |
tRNA aminoacylation for protein translation |
cellular_component |
GO:0005737 |
cytoplasm |
molecular_function |
GO:0004812 |
aminoacyl-tRNA ligase activity |
molecular_function |
GO:0005524 |
ATP binding |
molecular_function |
GO:0016876 |
ligase activity, forming aminoacyl-tRNA and related compounds |
molecular_function |
GO:0000166 |
nucleotide binding |
molecular_function |
GO:0004829 |
threonine-tRNA ligase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
IPR002320 | Threonine-tRNA ligase, class IIa | PRINTS | PR01047 | TRNASYNTHTHR | coord: 613..625 score: 56.87 coord: 586..599 score: 71.43 coord: 441..464 score: 67.86 coord: 542..570 score: 60.59 coord: 408..436 score: 55.54 |
IPR002320 | Threonine-tRNA ligase, class IIa | TIGRFAM | TIGR00418 | TIGR00418 | coord: 154..705 e-value: 4.5E-205 score: 680.8 |
IPR002320 | Threonine-tRNA ligase, class IIa | HAMAP | MF_00184 | Thr_tRNA_synth | coord: 148..710 score: 29.333 |
IPR012947 | Threonyl/alanyl tRNA synthetase, SAD | SMART | SM00863 | tRNA_SAD_4 | coord: 249..298 e-value: 5.4E-16 score: 69.1 |
IPR012947 | Threonyl/alanyl tRNA synthetase, SAD | PFAM | PF07973 | tRNA_SAD | coord: 250..298 e-value: 4.5E-11 score: 42.6 |
IPR002314 | Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) | PFAM | PF00587 | tRNA-synt_2b | coord: 400..608 e-value: 1.6E-37 score: 129.1 |
IPR004095 | TGS | PFAM | PF02824 | TGS | coord: 83..143 e-value: 1.9E-16 score: 59.8 |
IPR004154 | Anticodon-binding | GENE3D | 3.40.50.800 | | coord: 611..723 e-value: 4.5E-32 score: 110.0 |
IPR004154 | Anticodon-binding | PFAM | PF03129 | HGTP_anticodon | coord: 620..708 e-value: 4.7E-19 score: 68.3 |
IPR004154 | Anticodon-binding | SUPERFAMILY | 52954 | Class II aaRS ABD-related | coord: 606..713 |
None | No IPR available | GENE3D | 3.30.930.10 | | coord: 302..610 e-value: 1.3E-142 score: 474.1 |
None | No IPR available | GENE3D | 3.30.54.20 | | coord: 225..253 e-value: 1.5E-15 score: 56.8 |
None | No IPR available | GENE3D | 3.30.980.10 | | coord: 150..224 e-value: 1.6E-13 score: 50.5 |
None | No IPR available | GENE3D | 3.30.980.10 | | coord: 254..301 e-value: 1.3E-8 score: 34.8 |
None | No IPR available | CDD | cd00860 | ThrRS_anticodon | coord: 618..708 e-value: 2.07503E-31 score: 117.22 |
None | No IPR available | CDD | cd01667 | TGS_ThrRS_N | coord: 83..144 e-value: 1.91259E-26 score: 102.58 |
None | No IPR available | SUPERFAMILY | 55681 | Class II aaRS and biotin synthetases | coord: 322..604 |
IPR012675 | Beta-grasp domain | GENE3D | 3.10.20.30 | | coord: 82..146 e-value: 9.8E-27 score: 92.6 |
IPR006195 | Aminoacyl-tRNA synthetase, class II | PROSITE | PS50862 | AA_TRNA_LIGASE_II | coord: 347..613 score: 25.253 |
IPR033728 | Threonine-tRNA ligase catalytic core domain | CDD | cd00771 | ThrRS_core | coord: 321..618 e-value: 0.0 score: 534.437 |
IPR012676 | TGS-like | SUPERFAMILY | 81271 | TGS-like | coord: 83..143 |
IPR018163 | Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain | SUPERFAMILY | 55186 | ThrRS/AlaRS common domain | coord: 146..320 |
Blast
BLAST of TCONS_00046703-protein vs. Swiss-Prot (Human)
Match: SYTC (Threonine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=TARS PE=1 SV=3) HSP 1 Score: 1090.49 bits (2819), Expect = 0.000e+0 Identity = 506/678 (74.63%), Postives = 583/678 (85.99%), Query Frame = 0
Query: 49 EMNPLPAYIEERLKIFDEIKAEHDASM-EAKEKTS--IKITLPDGKQVDGFSWKTTPYEVAQGISQGLADNSVVAKVNGVLWDLDRPVEEDCTIELVKFDQPEGQQVFWHSSAHILGEAMERHYGGCLCYGPPIEEGFYYDMSIDDRQVSSNDFSALESVVKKIIKEKQQFVRLEMKKEDLLKMFAYNPFKLRILNERVTTPTTTVYRCGPLIDLCRGPHVRHTGKTKAIAVTKNSATYWEGKAEAESLQRIYGISFPNDKMLKEWKHFQEEAAKRDHRKIGREQELFFFHELSPGSCFFLPNGAHIYNTLVKFIRDEYKKRGFQEVISPNIYSTKLWETSGHWQHYSTNMFSFEVEKERYALKPMNCPGHCVMFDHRPRSWRELPLRMADFGVLHRNELSGTLTGLTRVRRFQQDDAHIFCRPDQIEEEIKSCLAFLRHVYDIFGFSFKLNLSTRPEKYMGDINMWNTAEKQLENSLNEFGEAWELNPGDGAFYGPKIDIQIKDALRRYHQCATIQLDFQLPERFNLNYVTGEGDERKRPVIIHRAILGSVERMMAILTENYGGKWPFWLSPRQAIVVPVSPKYDEYAKKVADDLKASDFKAEANLDAGETLNKKIRNAQLAHYNFILVVGDKEQSSNTVNVRTRDNKVHGEKTVEALFARFNDLMKTKKDDSEAEF 723
E+NP P YI RL++++ +KAEHD+ + E EK S IK+TLPDGKQVD SWKTTPY++A GISQGLADN+V+AKVN V+WDLDRP+EEDCT+EL+KF+ E Q V+WHSSAHI+GEAMER YGGCLCYGPPIE GFYYDM +++ VSSNDFS+LE++ KKIIKEKQ F RLE+KKE LL MF YN FK RILNE+V TPTTTVYRCGPLIDLCRGPHVRHTGK KA+ + KNS+TYWEGKA+ E+LQRIYGISFP+ KMLKEW+ FQEEA RDHRKIGR+QEL+FFHELSPGSCFFLP GA+IYN L++FIR EY+KRGFQEV++PNI++++LW TSGHWQHYS NMFSFEVEKE +ALKPMNCPGHC+MFDHRPRSWRELPLR+ADFGVLHRNELSG LTGLTRVRRFQQDDAHIFC +QIE+EIK CL FLR VY +FGFSFKLNLSTRPEK++GDI +W+ AEKQLENSLNEFGE WELN GDGAFYGPKIDIQIKDA+ RYHQCATIQLDFQLP RFNL YV+ +GD++KRPVI+HRAILGSVERM+AILTENYGGKWPFWLSPRQ +VVPV P DEYA+KV + F A+ +LD G TLNKKIRNAQLA YNFILVVG+KE+ S TVN+RTRDNKVHGE+T+ R L + + +E EF
Sbjct: 46 ELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEEGGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 723
The following BLAST results are available for this feature:
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