TCONS_00046910-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00046910-protein
Unique Name	TCONS_00046910-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1262

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00046910-protein ID=TCONS_00046910-protein|Name=TCONS_00046910-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1262bp
MSLLKYFKPTPKKTTPKSEDSVKLAIGEIVWTKLSDFPWWPCFVCKEPGS
EKLFDENSVHVQFFGDPPTRDWVLKRNVKQFSSMKPHENEEDVKAAFKEA
CEAEKLSKEKRIEQYYADDLSESDDQETNNNDVKEDEEDDDKENTTKGGQ
KRSLSSKPKSRKRIKLCIESESDEEFDDETKDETFKPEEKASSEEEEMQS
DDSVSSTEKKPKSVSTPKVNGSIKRKISTPNNNSFKDQTPNKKLNASISR
AQSTLSKFSSPVQAPPSPSVMDSECTQYTHNRLEFLKDGKRKDKQGRLHT
DSEYDSRTLLVPDWFLNDSKEVTPGLKQWWILKSKMYDTVIFFKVGKFYE
FYHMDADVGVKELGLLYMKGKFAHCGFPEVAFERYSDILIQRGYKVARIE
QTETPQALAARGGGKVVKREVCAIITKGTRTYGIMEAKGDESSAAYLLAF
VEKPCPDGQIGESEFGVCFVDTSIGKFYLGQFVDDRQCSRFLTMISQFPP
VQVLYEKKGLSPKISSILNNELLASIKEPLNPGSEFWDSAKTLKTFHKEN
YFADRKDDQVHWPPLLKEVLEEGDKVGLEAPISFQLAISALGACTWYLKK
CCIEQELLSMCQFQKYIPPDDVTQKKKVQDNTLGQHMILDGITLTNLDII
QNADGGTEGTLLELLSFCATIFGKRYFTQWLCMPLCQKKLIDARLDAVED
LMNNNSVFNDCRSIMKQLPDLDRVLRRIHAMGSLRRSQDHPEGRAVYFNI
DVFNKKKIADLLSAIEGFQKVLNIIELARKHDFKSKLINNLVQLEDEGLG
FPDLKPMLHFFKMAFDHRKARETGTIHPKPGVDNDYDAAQCDIELINDKL
NNYLKTQRKRLGYTNIHYWGNGKNRFQLEVPEDALRKSTPEDYHLKSQKK
GYKRFYTDFIVKMIEQLTKAEERRDNALNDTLRSIFNKFDQHYLVWQKAV
HLLATLDCLMSLAIYSRNISGVSCRPEIIDIVDGEGNERKPFIELRNSRH
PCSALSWKGEDFIPNDILLGIDEEGKTDDSTFVLITGPNMGGKSTLMRQA
GTILIMAQLGCYVPADVCRFTPVDRVFTRLGARDRIMHGESTFFVELSET
SIIFQHATKHSLVLLDELGRGTATFDGTAIASSVVNELSTKYNCRTFFST
HYHSLVDDFTENPKVKLGHMACMVEKEDESITDPTEETITFLYKFTGGAC
PKSYGFNAAALAGIPKTIIKRAHEKAVQFEESTKNLKHLRSLLNAAKENK
LRTDILKELCIR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_029930	XLOC_029930	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00046910	TCONS_00046910	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR007696	DNA_mismatch_repair_MutS_core
IPR000432	DNA_mismatch_repair_MutS_C
IPR000313	PWWP_dom
IPR007861	DNA_mismatch_repair_MutS_clamp
IPR016151	DNA_mismatch_repair_MutS_N
IPR007860	DNA_mmatch_repair_MutS_con_dom
IPR007695	DNA_mismatch_repair_MutS-lik_N
IPR027417	P-loop_NTPase

Vocabulary: **Molecular Function**
Term	Definition
GO:0030983	mismatched DNA binding
GO:0005524	ATP binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006298	mismatch repair

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006298	mismatch repair
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0030983	mismatched DNA binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 910..930
None	No IPR available	COILS	Coil	Coil	coord: 1229..1249
None	No IPR available	GENE3D	3.40.50.300		coord: 973..1258 e-value: 2.3E-44 score: 151.0
None	No IPR available	PIRSF	PIRSF037677	Msh6	coord: 14..1260 e-value: 0.0 score: 1168.1
None	No IPR available	GENE3D	1.10.1420.10		coord: 637..813 e-value: 9.1E-30 score: 103.9 coord: 820..971 e-value: 1.9E-11 score: 44.1
None	No IPR available	GENE3D	2.30.30.140		coord: 20..115 e-value: 5.1E-16 score: 58.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 115..273
None	No IPR available	SUPERFAMILY	63748	Tudor/PWWP/MBT	coord: 19..138
IPR007696	DNA mismatch repair protein MutS, core	SMART	SM00533	DNAend	coord: 656..1006 e-value: 1.4E-60 score: 217.3
IPR007696	DNA mismatch repair protein MutS, core	PFAM	PF05192	MutS_III	coord: 643..963 e-value: 1.5E-33 score: 116.6
IPR007696	DNA mismatch repair protein MutS, core	SUPERFAMILY	48334	DNA repair protein MutS, domain III	coord: 640..968
IPR000432	DNA mismatch repair protein MutS, C-terminal	SMART	SM00534	mutATP5	coord: 1030..1227 e-value: 9.6E-106 score: 367.3
IPR000432	DNA mismatch repair protein MutS, C-terminal	PFAM	PF00488	MutS_V	coord: 1034..1229 e-value: 1.6E-68 score: 230.4
IPR000432	DNA mismatch repair protein MutS, C-terminal	PROSITE	PS00486	DNA_MISMATCH_REPAIR_2	coord: 1111..1127
IPR000313	PWWP domain	SMART	SM00293	PWWP_4	coord: 24..82 e-value: 2.2E-11 score: 53.8
IPR000313	PWWP domain	PFAM	PF00855	PWWP	coord: 25..103 e-value: 4.9E-15 score: 55.7
IPR000313	PWWP domain	PROSITE	PS50812	PWWP	coord: 26..84 score: 15.59
IPR007861	DNA mismatch repair protein MutS, clamp	PFAM	PF05190	MutS_IV	coord: 831..923 e-value: 8.6E-13 score: 48.4
IPR016151	DNA mismatch repair protein MutS, N-terminal	GENE3D	3.40.1170.10		coord: 316..446 e-value: 7.8E-43 score: 145.1
IPR016151	DNA mismatch repair protein MutS, N-terminal	SUPERFAMILY	55271	DNA repair protein MutS, domain I	coord: 317..429
IPR007860	DNA mismatch repair protein MutS, connector domain	PFAM	PF05188	MutS_II	coord: 446..604 e-value: 3.2E-11 score: 43.6
IPR007860	DNA mismatch repair protein MutS, connector domain	GENE3D	3.30.420.110		coord: 447..620 e-value: 6.5E-33 score: 113.6
IPR007860	DNA mismatch repair protein MutS, connector domain	SUPERFAMILY	53150	DNA repair protein MutS, domain II	coord: 440..509 coord: 553..652
IPR007695	DNA mismatch repair protein MutS-like, N-terminal	PFAM	PF01624	MutS_I	coord: 323..431 e-value: 3.7E-33 score: 114.0
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 990..1230

Blast

[Close]

BLAST of TCONS_00046910-protein vs. Swiss-Prot (Human)
Match: MSH6 (DNA mismatch repair protein Msh6 OS=Homo sapiens GN=MSH6 PE=1 SV=2)

HSP 1 Score: 1103.97 bits (2854), Expect = 0.000e+0
Identity = 605/1298 (46.61%), Postives = 820/1298 (63.17%), Query Frame = 0

Query:   12 KKTTPKSEDSVKLAIGEIVWTKLSDFPWWPCFVCKEPGSEKLFDENS----VHVQFFGDPPTRDWVLKRNVKQFSSMKPHENEE---------DVKAAFKEACEAEKLSKEKRIEQYYADDLSESDDQE---TNNNDVKEDEEDDDKENTTKGGQKRSLSSKPKSRKRIKLCIESESDEEFDDETKDETFKPEEKASSEEEEMQSD--DSVSSTEKKPKSVSTPKV-----NGSIKRKISTPNNNSFKDQTPN--KKLNASISRAQSTLSKFSSPVQAPPSPSVM-----DSECTQYTHNRLEFLKDGKRKDKQGRLHTDSEYDSRTLLVPDWFLNDSKEVTPGLKQWWILKSKMYDTVIFFKVGKFYEFYHMDADVGVKELGLLYMKGKFAHCGFPEVAFERYSDILIQRGYKVARIEQTETPQALAARGG--------GKVVKREVCAIITKGTRTYGIMEAKGDESSAAYLLAFVEKPCPDGQIGESEFGVCFVDTSIGKFYLGQFVDDRQCSRFLTMISQFPPVQVLYEKKGLSPKISSILNNELLASIKEPLNPGSEFWDSAKTLKTFHKENYFADRKDDQ--VHWPPLLKEVLEEGDKVGLEAPISFQLAISALGACTWYLKKCCIEQELLSMCQFQKYIPPDD---VTQKKKVQDNTLGQHMILDGITLTNLDIIQNA-DGGTEGTLLELLSFCATIFGKRYFTQWLCMPLCQKKLIDARLDAVEDLMNNNSVFNDCRSIMKQLPDLDRVLRRIHAMGSLRRSQDHPEGRAVYFNIDVFNKKKIADLLSAIEGFQKVLNIIELARK--HDFKSKLINNLVQLED---EGLGFPDLKPMLHFFKMAFDHRKARETGTIHPKPGVDNDYDAAQCDIELINDKLNNYLKTQRKRLGYTNIHYWGNGKNRFQLEVPEDALRKSTPEDYHLKSQKKGYKRFYTDFIVKMIEQLTKAEERRDNALNDTLRSIFNKFDQHYLVWQKAVHLLATLDCLMSLAIYSRNISGVSCRPEIIDIVDGEGNERKPFIELRNSRHPCSALSWKGEDFIPNDILLGIDEEGKTDDSTF-VLITGPNMGGKSTLMRQAGTILIMAQLGCYVPADVCRFTPVDRVFTRLGARDRIMHGESTFFVELSETSIIFQHATKHSLVLLDELGRGTATFDGTAIASSVVNELSTKYNCRTFFSTHYHSLVDDFTENPKVKLGHMACMVEKEDESITDPTEETITFLYKFTGGACPKSYGFNAAALAGIPKTIIKRAHEKAVQFEESTKNLKHLRSLLNAAKENKLRTDILKEL 1259
            +   P +  S   + G++VW K+  +PWWPC V   P       E      VHVQFF D PTR WV KR +K ++  K  E ++         ++  A + A EA    K KR+E    D+ SE +++E        V +  E+D++  + +  Q ++  S+  SR+  K  + S  D E D    D  FKP+ K     +E+ S   DS S     P  V+  +      NGS+KRK S       + +TP+  K+  +  S  ++TL  FS+P  +     V       S  T + H  LE+LK+ KR+D+  R     ++D+ TL VP+ FLN     TPG+++WW +KS+ +D VI +KVGKFYE YHMDA +GV ELGL++MKG +AH GFPE+AF RYSD L+Q+GYKVAR+EQTETP+ + AR           +VV+RE+C IITKGT+TY ++E    E+ + YLL+  EK   D       +GVCFVDTS+GKF++GQF DDR CSRF T+++ +PPVQVL+EK  LS +  +IL + L  S++E L PGS+FWD++KTL+T  +E YF ++  D   V  P +LK +  E D +GL      +LA+SALG C +YLKKC I+QELLSM  F++YIP D     T +         Q M+LD +TL NL+I  N  +G TEGTLLE +  C T FGKR   QWLC PLC    I+ RLDA+EDLM      ++   ++K+LPDL+R+L +IH +GS  +SQ+HP+ RA+ +    ++KKKI D LSA+EGF+ +  II +  +    FKSK++  ++ L+    EG  FPDL   L+ +  AFDH KAR+TG I PK G D+DYD A  DI      L  YL+ QR R+G   I YWG G+NR+QLE+PE+   ++ PE+Y LKS KKG KR++T  I K +  L  AEERRD +L D +R +F  FD++Y  WQ AV  +A LD L+ LA YSR   G  CRP I+   D       PF+EL+ SRHPC   ++ G+DFIPNDIL+G +EE + +   + VL+TGPNMGGKSTLMRQAG + +MAQ+GCYVPA+VCR TP+DRVFTRLGA DRIM GESTFFVELSET+ I  HAT HSLVL+DELGRGTATFDGTAIA++VV EL+    CRT FSTHYHSLV+D+++N  V+LGHMACMVE E E   DP++ETITFLYKF  GACPKSYGFNAA LA +P+ +I++ H KA +FE+  ++L+  R +  A++ + +  + + +L
Sbjct:   78 RSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRRVIS--DSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSS-------RKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNS---CTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKE-EDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGR-FPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPED-----TPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECE---DPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKL 1353

The following BLAST results are available for this feature:

BLAST of TCONS_00046910-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00046910-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
MSH6	0.000e+0	46.61	DNA mismatch repair protein Msh6 OS=Homo sapiens G...	[more]

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TCONS_00046910-protein (polypeptide) - C. hemisphaerica