TCONS_00047016-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00047016-protein
Unique Name	TCONS_00047016-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1259

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00047016-protein ID=TCONS_00047016-protein|Name=TCONS_00047016-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1259bp
MTSSTATCQFLQIGDCISLYAEGGVSGFLSTLGLVDDRVVVEPDAGNLKN
PPNKFRDCLFKVCPMNRYSAQNQFWKSAKPTLSSTSDTVLLKKLHHAAEL
EKKQNEEENRKSIGEIVKYGGTIQLLHPKSNKYLTVNKRLPALLEKNAMR
VSLDNEGNEGSWFFISPYYKLRSSGDNVVIGDKVILNPVSAAQPLHASKF
ELPDKPGSREINSINCNTCWKINLFLDHLENDPDVLKGGDVVRLFHAEQE
KFLTHDDYQKKSHVFLRTTARASATSATSSKALWVVEVVQHDPCLSGAAR
WNSLFRFKHLATGRYLAAEVDESQHKDSNRLKLRGTGQVYHLTCVSNPND
LATIFELDPTSAQRVDDMVPKSSYTRLKHLCTGTWVHSTSIPIDVSEDRP
VMHKVGSAQIKEDKEAFAIIQVQADEVRDLDFVSDASKALSIFCQKMEEG
IISQIERRALTQLLADLNLFVLKKDMTMTKQDVLSISVDETDRERQKLIR
EQNILKKIFQLLRAPFLDKGEGGPLLKIDEIGEQRNAPIRHILRLSYRLL
RNSTRDYRKNQEYVAKQFGFMQSQIGYDLLAEETITDLVHNNRKLLEKHI
TAKEIDTFVLLVRKRKDCRFLDYLSDLCVSNNTAIPAMQELICKAVLNAN
NSDLLIETRMHHGEVHLFWDGGTQMKPQRLLARDAKIGQREDINLLNYYK
YQLHLFAQMCLDRQYLAINTISKQLDIELMIRCIADEGLPCSLRAAFCRL
MVHMHIDRDPQEKVSPVRYARLWSKIPTRNTVEEYDNHLREEQGDGKTSK
VTVSQFKPTMNFVENYLHNIAVSHGMGFMDPDQNKLTYEVVQVAYHLIHF
GFYGFKDLLRLTKMLLVILDSEEGKSYSMNPACDLTSHASVTDTLHAVGS
ALTHVALGMEAESWQAPTNQQKQTVSFEVLPTMVGVGKQSSTPSDTPGGS
GLTVMNTKLKVIEILEYIMDVRLDYRMSSLLTIFKKDFNENGASDSLDGD
GGGVDLDHISAEAEKMFETSIDGYIDLDLDNQGGKMFLRVLLNLSMAEYK
PLVSGVLKLLFRHFSQRKEVLQAFKQVQLLVSNEDVQNYQQIKKDLDELR
LKVEKSELWVYTGRSSSPIPALRSLRKRQSKLPENVQEVSDDVKKEIRMS
ESSSNQDDTASIVDSGYDNKQKLMSKLSGESFEQENEHNLMEGLSSKNWE
NYKIVLKILQRLCDLCLTADGKRNRKHEQRLLRNMGAHNVVLDLLGIPYE
KVPFDLFRV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_029997	XLOC_029997	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00047016	TCONS_00047016	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000493	InsP3_rcpt-bd
IPR016093	MIR_motif
IPR014821	Ins145_P3_rcpt
IPR000699	RIH_dom

Vocabulary: **Cellular Component**
Term	Definition
GO:0005783	endoplasmic reticulum
GO:0016020	membrane

Vocabulary: **Molecular Function**
Term	Definition
GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262	calcium channel activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006816	calcium ion transport
GO:0070588	calcium ion transmembrane transport

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0070588	calcium ion transmembrane transport
biological_process	GO:0006816	calcium ion transport
cellular_component	GO:0005783	endoplasmic reticulum
cellular_component	GO:0016020	membrane
molecular_function	GO:0005262	calcium channel activity
molecular_function	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 91..111
None	No IPR available	GENE3D	2.80.10.50		coord: 2..228 e-value: 9.6E-72 score: 240.7
None	No IPR available	GENE3D	2.80.10.50		coord: 229..421 e-value: 3.9E-54 score: 182.8
None	No IPR available	GENE3D	1.25.10.30		coord: 1081..1253 e-value: 8.9E-9 score: 34.5 coord: 422..589 e-value: 8.9E-44 score: 148.4
IPR000493	Inositol 1,4,5-trisphosphate-binding protein receptor	PRINTS	PR00779	INSP3RECEPTR	coord: 411..436 score: 64.87 coord: 576..600 score: 78.93 coord: 739..760 score: 68.79 coord: 237..257 score: 86.67 coord: 132..151 score: 91.67 coord: 838..863 score: 63.59 coord: 53..76 score: 83.06 coord: 291..315 score: 71.2 coord: 544..566 score: 67.83
IPR016093	MIR motif	SMART	SM00472	mir_2	coord: 114..168 e-value: 1.7E-4 score: 31.0 coord: 233..289 e-value: 6.3E-5 score: 32.4 coord: 296..390 e-value: 0.018 score: 24.2 coord: 175..225 e-value: 0.69 score: 17.5
IPR016093	MIR motif	PFAM	PF02815	MIR	coord: 235..419 e-value: 2.5E-59 score: 200.1
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 233..289 score: 9.948
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 366..422 score: 7.403
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 175..225 score: 7.256
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 296..360 score: 9.483
IPR016093	MIR motif	PROSITE	PS50919	MIR	coord: 114..168 score: 10.046
IPR016093	MIR motif	SUPERFAMILY	82109	MIR domain	coord: 111..206
IPR016093	MIR motif	SUPERFAMILY	82109	MIR domain	coord: 238..421
IPR014821	Inositol 1,4,5-trisphosphate/ryanodine receptor	PFAM	PF08709	Ins145_P3_rec	coord: 9..230 e-value: 5.9E-83 score: 277.2
IPR000699	RIH (RyR and IP3R Homology) domain	PFAM	PF01365	RYDR_ITPR	coord: 462..660 e-value: 1.6E-52 score: 177.8
IPR000699	RIH (RyR and IP3R Homology) domain	SUPERFAMILY	100909	IP3 receptor type 1 binding core, domain 2	coord: 1103..1130 coord: 1198..1251
IPR000699	RIH (RyR and IP3R Homology) domain	SUPERFAMILY	100909	IP3 receptor type 1 binding core, domain 2	coord: 425..592

Blast

[Close]

BLAST of TCONS_00047016-protein vs. Swiss-Prot (Human)
Match: ITPR1 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens GN=ITPR1 PE=1 SV=3)

HSP 1 Score: 1368.99 bits (3542), Expect = 0.000e+0
Identity = 717/1310 (54.73%), Postives = 906/1310 (69.16%), Query Frame = 0

Query:   10 FLQIGDCISLYAEGGVSGFLSTLGLVDDRVVVEPDAGNLKNPPNKFRDCLFKVCPMNRYSAQNQFWKSAKPTLSSTSDTVLLKKLHHAAELEKKQNEEENRKSIGEIVKYGGTIQLLHPKSNKYLTVNKRLPALLEKNAMRVSLDNEGNEGSWFFISPYYKLRSSGDNVVIGDKVILNPVSAAQPLHASKFELPDKPGSREINSINCNTCWKINLFLDHLENDPDVLKGGDVVRLFHAEQEKFLTHDDYQKKSHVFLRTTARASATSATSSKALWVVEVVQHDPCLSGAARWNSLFRFKHLATGRYLAAEVD--------ESQ-----HKDSNRLKLRGTGQ--VYHLTCVSNPNDLATIFELDPTSAQRVDDMVPKSSYTRLKHLCTGTWVHSTSIPIDVSEDRPVMHKVGSAQIKEDKEAFAIIQVQADEVRDLDFVSDASKALSIFCQKMEEGIISQIERRALTQLLADLNLFVLKKDMTMTKQDVLSISVDETDRERQKLIREQNILKKIFQLLRAPFLDKGEGGPLLKIDEIGEQRNAPIRHILRLSYRLLRNSTRDYRKNQEYVAKQFGFMQSQIGYDLLAEETITDLVHNNRKLLEKHITAKEIDTFVLLVRKRKDCRFLDYLSDLCVSNNTAIPAMQELICKAVLNANNSDLLIETRM----------------------HHGEVHLFW-DGGTQMKPQ--RLLARDAKIGQREDINLLNYYKYQLHLFAQMCLDRQYLAINTISKQLDIELMIRCIADEGLPCSLRAAFCRLMVHMHIDRDPQEKVSPVRYARLWSKIPTRNTVEEYDNHLREEQGDGKTSKVTVSQFKPTMNFVENYLHNIAVSHGMGFMDPDQNKLTYEVVQVAYHLIHFGFYGFKDLLRLTKMLLVILDS------------EEGKSYSMNPACDLTSHASVTDTLHAVGSALTHVALGMEAESWQAPTNQQKQTVSFEVLP-TMVGVGKQSSTPSDTPGGSGLTVMNTKLKVIEILEYIMDVRLDYRMSSLLTIFKKDFNENGASDSLDGDG-----------GGVDLDHISAEAEKMFETSIDGYIDLDLDNQGGKMFLRVLLNLSMAEYKPLVSGVLKLLFRHFSQRKEVLQAFKQVQLLVSNEDVQNYQQIKKDLDELRLKVEKSELWVYTGRSSSPIPALRSLRKRQSKLPENVQEVSDDVKKEIRMSESSSNQDDTASIVDSGYDNKQKLMSKLSGESFEQENE--HNLMEGLSSKNWENYKIVLKILQRLCDLCL--TADGKRNRKHEQRLLRNMGAHNVVLDLLGIPYEK 1251
            FL IGD  SLYAEG  +GF+STLGLVDDR VV+P+ G+L NPP KFRDCLFK+CPMNRYSAQ QFWK+AKP  +ST+D VLL KLHHAA+LEKKQNE ENRK +G +++YG  IQLLH KSNKYLTVNKRLPALLEKNAMRV+LD  GNEGSWF+I P+YKLRS GD+VVIGDKV+LNPV+A QPLHAS  +L D PG  E+NS+NCNT WKI LF+   +N  D+LKGGDVVRLFHAEQEKFLT D+++KK HVFLRTT R SATSATSSKALW VEVVQHDPC  GA  WNSLFRFKHLATG YLAAEVD        E Q      +D++R +LR   +  VY L  V   ND+++IFELDPT+ +  D +VP++SY RL+HLCT TWVHST+IPID  E++PVM K+G++ +KEDKEAFAI+ V   EVRDLDF +DASK L     K+E+G I+Q ERR++T+LL DL  FV     T + QDVL +   + +RERQKL+REQNILK+IF+LL+APF D G+ GP+L+++E+G+QR+AP RHI RL YR+LR+S +DYRKNQEY+AKQFGFMQ QIGYD+LAE+TIT L+HNNRKLLEKHITA EIDTFV LVRK ++ RFLDYLSDLCVS N +IP  QELICKAVLN  N+D+LIET++                         EV LFW D   +++ +  R LA+DAK GQ+ED ++L+YY+YQL+LFA+MCLDRQYLAIN IS QLD++L++RC++DE LP  LRA+FCRLM+HMH+DRDPQE+V+PV+YARLWS+IP+   +++YD+        G +      +F  TM FVE YL ++ V     F D ++NKLT+EVV +A +LI+FGFY F DLLRLTK+LL ILD              +G+    N   +    ++V  ++H VG  +T V L                      LP T +    + +     P    + VM+TKLK+IEIL++I++VRLDYR+S LL IFK++F+E+ +  S    G           G +D +HI  +AE +F  S +    LDLD+ GG+ FLRVLL+L+M +Y PLVSG L+LLFRHFSQR+EVLQAFKQVQLLV+++DV NY+QIK+DLD+LR  VEKSELWVY G+                                          D+T              M   SGE+  ++ E  +N  +   S +  NY++V +IL RL  LC+  +A  +++RK +QRLLRNMGAH VVL+LL IPYEK
Sbjct:    8 FLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGG--TNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGD-GPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS-------SGASKDEIKERFAQTMEFVEEYLRDV-VCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGG-----------------FLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEEN-TPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGP----------------------------------------DET--------------MDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEK 1234

The following BLAST results are available for this feature:

BLAST of TCONS_00047016-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00047016-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ITPR1	0.000e+0	54.73	Inositol 1,4,5-trisphosphate receptor type 1 OS=Ho...	[more]

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TCONS_00047016-protein (polypeptide) - C. hemisphaerica