TCONS_00047480-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00047480-protein
Unique Name	TCONS_00047480-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	481

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00047480-protein ID=TCONS_00047480-protein|Name=TCONS_00047480-protein|organism=Clytia hemisphaerica|type=polypeptide|length=481bp
MDLTICYMVTMATILVSIIDAQKGNYSRGLSGEFRLKKFLMDEYNPEVRP
VVNDRDIVNLTFEIALQQIVEVNEKEESLSISVFFRQYWHDPNLMWDPLD
YGNVTSTNFNPEMLWKPDVALYNNVEKDVEFGGQLDLLKNRIIVYHDGNV
VWYSLGILNGKCPMNIRYFPFDTQICDFKFGPWTYHGHLVDIYPKRQVVD
TAAYTIHSEWHLKSAEHIRNVAYYGCCVEPYPDVTVKIVLERRPLFYVLN
LLLPMILIGVLTLLAFYLPAQSGERVSFAVTLLLAMTVFMLIVADMVPAS
SETIPLLGIFFTAVMVEMVLMVFSMCYVLKLHLIQPDDGEEIGPFMRRFV
YDFLSYKFGTRKRRTDFARDEYKFHLQDSKTWDKNGSTKSHNGGHSYGQV
INNGQDDGSRNIGAGDVDDSSTAALMEKNLRVMTDKMKEEENEKRIKQEF
EICATTLDILALICFVALFILITTVYFVATT

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_030243	XLOC_030243	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00047480	TCONS_00047480	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 423..443
None	No IPR available	GENE3D	1.20.58.390		coord: 250..481 e-value: 2.4E-39 score: 133.9
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 113..124 score: 45.21 coord: 80..96 score: 35.48 coord: 238..250 score: 36.79 coord: 162..176 score: 51.19
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 11..478 e-value: 3.7E-86 score: 287.6
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 251..477 e-value: 4.4E-32 score: 111.9
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 244..479
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 22..249 e-value: 2.2E-66 score: 223.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 35..244 e-value: 1.0E-57 score: 195.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 33..244
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 162..176

Blast

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BLAST of TCONS_00047480-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 242.662 bits (618), Expect = 2.366e-74
Identity = 144/475 (30.32%), Postives = 246/475 (51.79%), Query Frame = 0

Query:   30 LSGEFRLK--KFLMDEYNPEVRPVVNDRDIVNLTFEIALQQIVEVNEKEESLSISVFFRQYWHDPNLMWDPLDYGNVTSTNFNPEMLWKPDVALYNNVEK--DVEFGGQLDLLKNRIIVYHDGNVVWYSLGILNGKCPMNIRYFPFDTQICDFKFGPWTYHGHLVDIYPKRQVVDTAAYTIHSEWHLKSAEHIRNVAYYGCCVEPYPDVTVKIVLERRPLFYVLNLLLPMILIGVLTLLAFYLPAQSGERVSFAVTLLLAMTVFMLIVADMVPASSETIPLLGIFFTAVMVEMVLMVFSMCYVLKLHLIQPDDGEEIGPFMRRFVYDFLSY-----KFGTRKRRTDFARDEYKFHLQD------SKTWDKNGS--------------TKSHNGGHSYGQVINNGQDDGSRNIGAGDVDDSSTAALMEKNLRVMTDKMKEEENEKRIKQEFEICATTLDILALICFVALFILITTV 475
            L GEF+ K  K L+  YNP  RPV ND   + + F ++L QI++V+EK + L+ +++ +  W D  L W+  +Y  V +  F    +WKPD+ LYN+ ++  D  F          ++V   G+  +   GI    C +++R+FPFD Q C  KFG W+Y G  +D+  + Q  D + Y  + EW L      R+  +Y CC EPYPDVT  + + RR L+Y LNLL+P +LI  L LL F LPA SGE++S  +T+LL++TVFML+VA+++PA+S+++PL+  +F + M+ + L V     VL+ H   PD G ++  + R  + ++ ++     + G  K R      + +  L        +     NG+                + + G   G++  +   D     G    +     A + + +R + ++ + ++  + +  E++  A  +D L L+ F ++F +I T+
Sbjct:   21 LQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF-------HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL--QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGG-KMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAF-SVFTIICTI 484

The following BLAST results are available for this feature:

BLAST of TCONS_00047480-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00047480-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	2.366e-74	30.32	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00047480-protein (polypeptide) - C. hemisphaerica