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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00047678-protein ID=TCONS_00047678-protein|Name=TCONS_00047678-protein|organism=Clytia hemisphaerica|type=polypeptide|length=727bp
MNGSLSFTGVMKLRIYEALGLEETKVRSSVITSIGVTSIDPYLQVNVDDE
NIYQTQKQVNTFSPEWNEDFQTNLKDAKVINFTVFHTSIVGGGAFVSNSA
IPLQEIIDEGQSDLWIKLEPAGKLHVFIELKPGQVDVNHSKIEDKARHFR
ERESSYLKKRGRRNAVRRRVHHVSGHKFMATYLRQFHFCSHCKEFIWGVF
SKQGYQCQVCQSVTHKKCHQFVVSKCPGVQAENQNSSKEKDEPRFSINIP
HRFQVHNYKRPTFCEHCGSLLYGLFRQGMQCQACQRNVHKRCQGNVPNDC
GVDAKKMAEVIKKEIDMTPDELIKISKKGSILKDGSPTKKLTSQTSKDEK
ITNNHNTTQNGETSNTNDTLEINPYLPTLPHSPGTKRHFFSDDRYTKDSF
TYLKVIGKGSFGKVMLAEKKGTSELYAIKILKKMTIIQDDDVECVMTEKR
VLTIAGQHPYLTSLHSCFQSDDRLFFVMEYVSGGDLMFQIQKARKFDEQR
SRFYAAEITLALQFLHKKGVIYRDLKLDNVLLDCGGHVKLADFGMCKDNM
LQNQYTSTFCGTPDYIAPEIVNEQDYAESVDWWALGVLMYEMMAGQPPFE
ADNEDELFQCILHSDVLYPVWLSREAISILKGFLTKNYEKRLGCVPGIGE
VAINKHPFFASIDWRKLEHRQVAPPFQPQIRSRTDVANFDTDFTRENPCL
TPTEKDVVNNINQDEFSGFSYVNPSFV Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
| GO:0035556 | intracellular signal transduction |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0005524 | ATP binding |
| GO:0004672 | protein kinase activity |
| GO:0004697 | protein kinase C activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004697 |
protein kinase C activity |
| molecular_function |
GO:0004674 |
protein serine/threonine kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR020454 | Diacylglycerol/phorbol-ester binding | PRINTS | PR00008 | DAGPEDOMAIN | coord: 189..198
score: 57.23
coord: 289..301
score: 50.8
coord: 203..214
score: 47.44
coord: 173..187
score: 31.62 |
| IPR000008 | C2 domain | SMART | SM00239 | C2_3c | coord: 10..115
e-value: 1.4E-7
score: 41.1 |
| IPR000008 | C2 domain | GENE3D | 2.60.40.150 | | coord: 4..132
e-value: 5.4E-17
score: 61.6 |
| IPR000008 | C2 domain | PFAM | PF00168 | C2 | coord: 11..118
e-value: 9.2E-14
score: 51.5 |
| IPR000008 | C2 domain | PROSITE | PS50004 | C2 | coord: 11..100
score: 9.894 |
| IPR000008 | C2 domain | SUPERFAMILY | 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | coord: 7..132 |
| IPR000961 | AGC-kinase, C-terminal | SMART | SM00133 | pkinase_C_6 | coord: 660..723
e-value: 4.7E-25
score: 99.2 |
| IPR000961 | AGC-kinase, C-terminal | PROSITE | PS51285 | AGC_KINASE_CTER | coord: 660..727
score: 18.85 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 176..226
e-value: 1.5E-9
score: 47.7
coord: 251..300
e-value: 1.6E-17
score: 74.2 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 251..302
e-value: 1.3E-17
score: 63.3
coord: 176..227
e-value: 1.0E-13
score: 50.9 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 251..300 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 250..300
score: 16.226 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 175..226
score: 14.451 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 176..226
e-value: 2.4715E-11
score: 59.0428 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 251..300
e-value: 1.06296E-17
score: 77.5323 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 400..659
e-value: 1.4E-97
score: 340.2 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 401..644
e-value: 2.1E-63
score: 214.1 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 400..659
score: 48.485 |
| IPR014376 | Protein kinase C, delta/epsilon/eta/theta types | PIRSF | PIRSF000551 | PKC_delta | coord: 5..727
e-value: 2.4E-293
score: 972.7 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 497..716
e-value: 4.7E-57
score: 192.4 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 246..314
e-value: 7.5E-23
score: 79.7 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 335..496
e-value: 5.0E-27
score: 93.7 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 174..242
e-value: 4.9E-18
score: 64.2 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 334..369 |
| None | No IPR available | CDD | cd05570 | STKc_PKC | coord: 404..722
e-value: 0.0
score: 617.69 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 166..227 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 244..304 |
| IPR017892 | Protein kinase, C-terminal | PFAM | PF00433 | Pkinase_C | coord: 680..721
e-value: 2.2E-9
score: 37.8 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 406..429 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 520..532 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 398..723 |
Blast
BLAST of TCONS_00047678-protein vs. Swiss-Prot (Human)
Match: KPCE (Protein kinase C epsilon type OS=Homo sapiens GN=PRKCE PE=1 SV=1) HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0 Identity = 383/739 (51.83%), Postives = 507/739 (68.61%), Query Frame = 0
Query: 7 FTGVMKLRIYEALGLEET--KVRSSVITSIGVTSIDPYLQVNVDDENIYQTQKQVNTFSPEWNEDFQTNLKDAKVINFTVFHTSIVGGGAFVSNSAIPLQEIIDEGQSDL--WIKLEPAGKLHVFIELKPGQVDVNHSKIEDKARHFRERESSYLKKRGRRNAVRRRVHHVSGHKFMATYLRQFHFCSHCKEFIWGVFSKQGYQCQVCQSVTHKKCHQFVVSKCPGVQAENQNSSKEKDEPRFSINIPHRFQVHNYKRPTFCEHCGSLLYGLFRQGMQCQACQRNVHKRCQGNVPNDCGVDAKKMAEVIKKEIDMTPDELIKISKKGSILKDGSPTKKLTSQTSKDEK-----------------ITNNHNTTQNGETSNTNDTLEINPYLPTLPHSPGTKRHFFSDD--RYTKDSFTYLKVIGKGSFGKVMLAEKKGTSELYAIKILKKMTIIQDDDVECVMTEKRVLTIAGQHPYLTSLHSCFQSDDRLFFVMEYVSGGDLMFQIQKARKFDEQRSRFYAAEITLALQFLHKKGVIYRDLKLDNVLLDCGGHVKLADFGMCKDNMLQNQYTSTFCGTPDYIAPEIVNEQDYAESVDWWALGVLMYEMMAGQPPFEADNEDELFQCILHSDVLYPVWLSREAISILKGFLTKNYEKRLGCVPGI-GEVAINKHPFFASIDWRKLEHRQVAPPFQPQIRSRTDVANFDTDFTRENPCLTPTEKDVVNNINQDEFSGFSY 721
F G++K++I EA+ L+ T +R +V +DPY+ +NVDD I QT + T SP W+++F T++ + + I VFH + +G FV+N I +E++ G WI LEP G+++V I+L + +++ R FRER ++ R R+ AVRRRVH V+GHKFMATYLRQ +CSHC++FIWGV KQGYQCQVC V HK+CH+ +++KC G++ Q + + RFS+N+PH+F +HNYK PTFC+HCGSLL+GL RQG+QC+ C+ NVH+RC+ NV +CGVDA+ +A+V+ ++ +TPD++ ++ L G+ + + S +S E+ + NN + + +P + SPG R D F ++KV+GKGSFGKVMLAE KG E+YA+K+LKK I+QDDDV+C MTEKR+L +A +HPYLT L+ CFQ+ DRLFFVMEYV+GGDLMFQIQ++RKFDE RSRFYAAE+T AL FLH+ GVIYRDLKLDN+LLD GH KLADFGMCK+ +L T+TFCGTPDYIAPEI+ E +Y SVDWWALGVLMYEMMAGQPPFEADNED+LF+ ILH DVLYPVWLS+EA+SILK F+TKN KRLGCV GE AI +HPFF IDW LE +++ PPF+P+I+++ DV NFD DFTRE P LT ++ +V INQ+EF GFSY
Sbjct: 4 FNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLEPEGRVYVIIDLSGSS---GEAPKDNEERVFRER----MRPRKRQGAVRRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK--KQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAKVLA-DLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLM--SPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSY 730
The following BLAST results are available for this feature:
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