TCONS_00049009-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00049009-protein
Unique Name	TCONS_00049009-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1061

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00049009-protein ID=TCONS_00049009-protein|Name=TCONS_00049009-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1061bp
MKLAGIELLLLLLVYPFTNCANVTSKDSGNAENVPRGSLDRTSLNSTQGT
KNDTNNLADILQNNISNQTDKAANQTTTQPTTLTPTTTTTLPPWKETPLH
IGIMVPDALKDQCIQAAIELAFEDVGKHPRLIQYSGSNMERNNPTFIREY
YKLTPYYSEVDLNISIAVQTLHDNYMKGPLKNALIGPPYERLQYDFIEYS
SVLGGTHISYTDIDEPIEPYYVFFVPTPPSINHQFKAAVALMDHFQWRRF
GILYDFSDSKYRRNSGTLRESILLYSQHKEETDVLTEIGIWSQKVDYSKX
ETDVLTEIGIWSQKVDYSKLNQKMDILKKNDRRIILSLFSVRGARLVFCQ
AYHKKMYKPKIVWVLFEKLKDGWAKPLVDGTKDVNCTEGQLLEAAHGHIF
ITKQILRRDGVPNISNMTSNQFLKRIRQKVNSNKCSDDIGYAYDSIWVLA
KGYEILSKSTWPRFYYYYNYAFGYLFAGTLKRINFEGLTGSFHYERDRSL
HKRLGQIAFYKYHKDGNHVYLGTHHTKTGKLDIIPNMVYKIFNSDKIPKD
KAIISYTYADIEKPLWITMWVIAFLGIIIALIVLVVILLYSNNTSYKIGS
PILNCVMIFGAILCYTSVIIYSLDTRLVNEDKIPKVCFTFLCALTIGFTM
TFGALFAKTWGLYKTFVTPPNHNNQQAEIKHVPEWVLLTMVGAFLLIDIV
LLISWGFMAPFHASLQVIYTNENFFADTVKTGQVVRCNCQYFIQLLIGLC
CYKGVLLLIGIFLAWQLKSTKIQVQNEAKQIAIAIYNVFAVSIIGVICVS
VLLNTKLHQALYAIVAICILICTTFTLLLVFVPKIKAILYPELEKPQPAS
AMKKEIYLRHSQRQYSRKQSHHRTSHTELSSTFSTGTLNTQLSVESTSTX
SSTFSTGTLNTQLSVESTSTVYGKDTNQHPALQDTLSSGSVVSYPPEYLS
SIPSSNNQSTILANIDEPITIEESNHVANAKDIQETRQERAITHVGHRDS
GLGDDSPNLEHILLTLKDKEIQENKKNMEKDITNIGNPNDLGEDTSSLNL
TPKSSDGMLDE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_031132	XLOC_031132	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00049009	TCONS_00049009	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR002456	GPCR_3_GABA_rcpt_B1
IPR001828	ANF_lig-bd_rcpt
IPR017978	GPCR_3_C
IPR020846	MFS_dom
IPR028082	Peripla_BP_I

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway

Vocabulary: **Molecular Function**
Term	Definition
GO:0004965	G-protein coupled GABA receptor activity
GO:0004930	G-protein coupled receptor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007186	G-protein coupled receptor signaling pathway
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0004965	G-protein coupled GABA receptor activity
molecular_function	GO:0004930	G-protein coupled receptor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002456	GPCR family 3, gamma-aminobutyric acid receptor, type B1	PRINTS	PR01177	GABAB1RECPTR	coord: 438..456 score: 36.84 coord: 564..589 score: 30.77 coord: 809..832 score: 29.17
None	No IPR available	PRINTS	PR01176	GABABRECEPTR	coord: 111..127 score: 43.85 coord: 812..834 score: 39.53 coord: 656..673 score: 24.24 coord: 637..656 score: 36.82
None	No IPR available	GENE3D	3.40.50.2300		coord: 229..556 e-value: 3.1E-17 score: 62.3
IPR001828	Receptor, ligand binding region	PFAM	PF01094	ANF_receptor	coord: 207..500 e-value: 5.9E-17 score: 61.7
IPR017978	GPCR family 3, C-terminal	PFAM	PF00003	7tm_3	coord: 577..835 e-value: 3.1E-38 score: 131.8
IPR017978	GPCR family 3, C-terminal	PROSITE	PS50259	G_PROTEIN_RECEP_F3_4	coord: 565..840 score: 20.365
IPR020846	Major facilitator superfamily domain	CDD	cd06174	MFS	coord: 552..830 e-value: 3.86302E-7 score: 50.7753
IPR028082	Periplasmic binding protein-like I	SUPERFAMILY	53822	Periplasmic binding protein-like I	coord: 98..550

Blast

[Close]

BLAST of TCONS_00049009-protein vs. Swiss-Prot (Human)
Match: GABR2 (Gamma-aminobutyric acid type B receptor subunit 2 OS=Homo sapiens GN=GABBR2 PE=1 SV=1)

HSP 1 Score: 248.054 bits (632), Expect = 1.454e-68
Identity = 203/733 (27.69%), Postives = 330/733 (45.02%), Query Frame = 0

Query:  221 YVFFVPTPPSINHQFKAAVALMDHFQWRRFGILYDFSDSKYRRNSGTLRESILLYSQHKEETDVLTEIGIWSQKVDYSKXET---DVLTEIGIWSQKVDYSKLNQKMDILKKNDRRIILSLFSVRGARLVFCQAYHKKMYKPKIVWVLFEKLKDGWAKPLVDGTKDVNCTEGQLLEAAHGHIFITKQILRRDGVPNISNMTSNQFLKRIRQKVNSNKCSDDIGYAYDSIWVLAK----GYEILSKSTWPRFYYYYNYA---FGYLFAGTLKRINFEGLTGSFHYERDRSLHKRLGQIAFYKYHKDGNHVYLGTHHTKTGKLDIIPNMVYKIFNSDKIPKDKAIISYTYADIEKPLWITMWVIAFLGIIIALIVLVVILLYSNNTSYKIGSPILNCVMIFGAILCYTSVIIYSLDTRLVNEDKIPKVCFTFLCALTIGFTMTFGALFAKTWGLYKTFVTPPNHNNQQAEIKHVPEWVLLTMVGAFLLIDIVLLISWGFMAPFHASLQVIYTNENFFADTVKTGQVVR-CNCQYFIQLLIGLCCYKGVLLLIGIFLAWQLKSTKIQVQNEAKQIAIAIYNVFAVSIIGVICVSVLLNTKLHQALYAIVAICILICTTFTLLLVFVPKIKAILYPELEKPQPASAMKKEIYLRHSQRQYSRKQSHHRTSHTELSSTFSTG--TLNTQLSVESTSTXSSTFSTGTLNTQLSVESTSTVYGKDTNQHPALQDTLSSGS 940
            Y +F  T PS N    A + L+ H+QW+R G               TL + +  +S+ + +   LT + ++ + ++ S  E+   D  T +                  LK ND RIIL  F    A  VFC AY + MY  K  W++    +  W + +        C    LL A  G+I +  + L    +  IS  T  Q+ +    K +    S   GYAYD IWV+AK      E L  S+  +    +NY     G +    +   NF G+TG   +       +R+G I F ++ +D   V +G ++     L+II + +   F   + PKDK II      I  PL+  +  +  LG+I+A   L   +   N    K+ SP +N ++I G +L Y S+ ++ LD   V+E     +C      LT+G+T  FGA+FAKTW ++  F       N + + K + +  LL +VG  LLID+ +LI W  + P   +++      +     +    ++  C   +    L  +  YKG+L+L G FLAW+ ++  I   N++K I +++YNV  + IIG   VS L   + +   + IVA+ I+ C+T TL LVFVPK+       L     A+   +      +Q++   K S   TS  + S++   G  + N +L ++ T          T+  Q + E T+ +     N +  L D L+ G+
Sbjct:  169 YPYFFRTVPSDNAVNPAILKLLKHYQWKRVG---------------TLTQDVQRFSEVRND---LTGV-LYGEDIEISDTESFSNDPCTSV----------------KKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNG----ERMGTIKFTQF-QDSREVKVGEYNAVADTLEIINDTIR--FQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIF------KNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGA-AVSFLTRDQPN-VQFCIVALVIIFCSTITLCLVFVPKLIT-----LRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITE-LDKDLEEVTMQLQDTPEKTTYI---KQNHYQELNDILNLGN 842

The following BLAST results are available for this feature:

BLAST of TCONS_00049009-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00049009-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GABR2	1.454e-68	27.69	Gamma-aminobutyric acid type B receptor subunit 2 ...	[more]

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TCONS_00049009-protein (polypeptide) - C. hemisphaerica