TCONS_00049460-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049460-protein
Unique NameTCONS_00049460-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length894

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049460-protein ID=TCONS_00049460-protein|Name=TCONS_00049460-protein|organism=Clytia hemisphaerica|type=polypeptide|length=894bp
MFSTPLLLILFTHLCGKVISTANGDKESVHVRIKRQQAPQNYQLPPHLRQ
PQPNNRQHFRLPAYLRQPQTNPYLRQPRPDPRYAPNRPRPNPRFPNPPSP
NTRFPQNQPRPDPRYQPRPDPRYQPRPNPRYPNQPRPTSNRGQPPRRPGP
FRPPPLRDLHGYQQSPTRPGEISINFINKSGRRINMFQSLPYGHETRFTF
TLRPNEPRRVSVQPDNSFWQAYDMTTSFPLYINGQPSLETYLLRQGTSVD
ARITSPNLRAEPVKRDRSVPRFIETQVVVDKSMLDHHGEQKVMNYTIMLM
NSVTRTFLHRSFGAPIYVSVVNIHLMKNKPSYYRIVTNRPEISVPGACRY
SREVAQRNNSVDFHLILTREDIGPAGFAAMYTMCSRRSCALVKENGPDTS
FVITHELAHALGIDHDEDDGCGRENLSGGNIMVKKLYATSSNFRWSKCSA
KMIWQNLKYFTCLKNKPKMLPTFKKSMDWLPGELMGIKDQCRSYHGSSAL
PCTPRNPLTACRYLWCRPNQSAPCQPVWWHAPLEGSTCAKSKWCKRGRCV
TKMKIKPVNGGWSKYSEFTPPCNRKSTRWIVQHRNRSCTNPKPRLSGKKC
QGSPNQYRILIPGRNGICKPFNMRQLLLSGEIDWENIRQNGCSYKNDNVT
KWRVYRESEQRRQVKSLNLTCDFESPGCGWKNSKKGVKGWNIGKGATPSH
RTGPSVDNTIKTKTGKYLYFEASWVSGTTPLRRGSRVILESPIIFSSQVC
MKFAYHMYGKGVGSLEIHIRRGKHSRKMWSKKGDQGDKWYQAEVELAINI
EYKITIEAVRGNSYYGDIAIDDIQFSYGLCNAKSSQDDKQICTNVCITQD
NSKMVRRRLPDGYPCKLPKSKNNVCFRQVCQPVNCHGVINGRKC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031382XLOC_031382Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049460TCONS_00049460Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000998MAM_dom
IPR000884TSP1_rpt
IPR024079MetalloPept_cat_dom
IPR001590Peptidase_M12B
IPR013320ConA-like_dom
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Molecular Function
TermDefinition
GO:0008237metallopeptidase activity
GO:0004222metalloendopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016020 membrane
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000998MAM domainSMARTSM00137MAM_2coord: 666..832
e-value: 2.0E-35
score: 133.7
IPR000998MAM domainPFAMPF00629MAMcoord: 671..831
e-value: 7.5E-36
score: 123.3
IPR000998MAM domainPROSITEPS50060MAM_2coord: 669..832
score: 31.1
IPR000998MAM domainCDDcd06263MAMcoord: 671..830
e-value: 1.76394E-40
score: 146.369
NoneNo IPR availableGENE3D2.60.120.200coord: 666..832
e-value: 7.0E-45
score: 152.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 60..172
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 269..466
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 558..609
e-value: 6.3E-7
score: 29.1
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 267..489
e-value: 3.7E-43
score: 147.3
IPR001590Peptidase M12B, ADAM/reprolysinPFAMPF01421Reprolysincoord: 271..467
e-value: 5.5E-14
score: 52.4
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 271..467
score: 12.243
IPR013320Concanavalin A-like lectin/glucanase domainSUPERFAMILY49899Concanavalin A-like lectins/glucanasescoord: 667..830

Blast
BLAST of TCONS_00049460-protein vs. Swiss-Prot (Human)
Match: ATS14 (A disintegrin and metalloproteinase with thrombospondin motifs 14 OS=Homo sapiens GN=ADAMTS14 PE=2 SV=2)

HSP 1 Score: 172.555 bits (436), Expect = 5.746e-44
Identity = 112/335 (33.43%), Postives = 172/335 (51.34%), Query Frame = 0
Query:  287 HGEQKVMNYTIMLMNSVTRTFLHRSFGAPIYVSVVNIHLMKNKPSYYRIVTNRPEISVPGACRYSREVAQRNNSVDFH----LILTREDIGPAGFAAMYTMCS-RRSCALVKENGPDTSFVITHELAHALGIDHD-EDDGCGRENLSGGNIMVKKLYATSSNFRWSKCSAKMIWQNLKYFTCLKNKPKMLPTFKKSMDWLPGELMGIKDQCRSYHGSSALPCTPRNPLTACRYLWCRPNQSAPCQPVWWHA----PLEGSTCAKSKWCKRGRCVTKM--KIKPVNGGWSKYSEFTPPCNRKSTRWIVQHRNRSCTNPKPRLSGKKCQGSPNQYRI 609
            HG++ V NY + LMN V   +   S G  I +++V + ++  + S   I    P  S+   CR++    +++ S   H    + LTR+D GP+G+A +  MC   RSCAL  E+G  ++FVI HE  H LG++HD + +GC  E  S G++M   + A    F WS+CS   + + L  + CL + P   P + +  + LPG    + +QCR   GS    C        C+ LWC    S P  P +       PL+G+ CA  KWC +G C+ K   +    +GGWS +++F   C+R S    V+ R+RSC NP P   G+ C G   +Y++
Sbjct:  275 HGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLIMVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGYAPVTGMCHPLRSCALNHEDGFSSAFVIAHETGHVLGMEHDGQGNGCADET-SLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDP-FDPAWPQPPE-LPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWC----SHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCIWKSPEQTYGQDGGWSSWTKFG-SCSR-SCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQV 600          
The following BLAST results are available for this feature:
BLAST of TCONS_00049460-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ATS145.746e-4433.43A disintegrin and metalloproteinase with thrombosp... [more]
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