TCONS_00050380-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050380-protein
Unique NameTCONS_00050380-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length752

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050380-protein ID=TCONS_00050380-protein|Name=TCONS_00050380-protein|organism=Clytia hemisphaerica|type=polypeptide|length=752bp
MDVDKNLKNGLNQSSSKDRYGMADSTKPNQTKRLVIKNFKSKPTLPSNYK
EVTWEKLREAVVAIHNQQSISSSLEELYKAVENLCSHDMSMNLYDRLKNV
CENYVKSIIKDFICDGMDNFMYLKKMNELWESHCRQMTMIRSIFLYLDRV
YVLQHSTILSLWDVGLHLWRTHILGNNSIQTRTVDSLLFLIEKERNGEAV
DGALLKSLLRMLADLQMYQDVFEERFLQATDLLYSAEGQRFMGEVDVPNY
LKHVDKRLKEESDRLLHYLDIGTRKPLILCVENQLISKHITNILNKGFES
LMDTNSSEHLNVMYALFSRVKDGQDKLCEYFGGYVKVKGLSIVQDVEKDK
TMVQELLDFKEKLDNFIEGAFKKNEKFVSAMKDSFEVFINKRQNKPAELI
AKFVDVKLKAGNKEASEEELEMRLDKIMILFRFIHGKDVFEAFYKKDLAK
RLLLGKSASVDAEKSMLSKLKQECGSAFTSKLEGMFKDMELSKDIMNTFK
QHISSQGDAPNIDLNVNILTMGYWPTYTPIEVNLPNEMVRLQEIFKTFYL
SKHSGRKLQWQATLGSCGVKAVFEKSNHELHVSLFQTMCLLLFNDADELS
YEDIRDATGIEENELKRTLQSLACGKLQSRVLKKKPPGKDINVKDRFFFN
ESFTLKLYRIKINQVQLKETAEENQLTNEQVFQDRQYQIDAAIVRILKTR
KTLSHTLLVTELYNQLKFPVKPSDIKKRIESLIDRDYMERDKENTNTYVY
VA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031902XLOC_031902Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050380TCONS_00050380Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR019559Cullin_neddylation_domain
IPR016158Cullin_homology
IPR011991WHTH_DNA-bd_dom
IPR001373Cullin_N
IPR016157Cullin_CS
IPR016159Cullin_repeat-like_dom
Vocabulary: Biological Process
TermDefinition
GO:0006511ubiquitin-dependent protein catabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0031625ubiquitin protein ligase binding
Vocabulary: Cellular Component
TermDefinition
GO:0031461cullin-RING ubiquitin ligase complex
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006511 ubiquitin-dependent protein catabolic process
cellular_component GO:0031461 cullin-RING ubiquitin ligase complex
molecular_function GO:0031625 ubiquitin protein ligase binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019559Cullin protein, neddylation domainSMARTSM00884Cullin_Nedd8_2coord: 681..746
e-value: 1.5E-36
score: 137.4
IPR019559Cullin protein, neddylation domainPFAMPF10557Cullin_Nedd8coord: 684..744
e-value: 4.0E-23
score: 81.1
IPR016158Cullin homologySMARTSM00182cul_2coord: 425..573
e-value: 7.0E-81
score: 284.7
IPR016158Cullin homologyPROSITEPS50069CULLIN_2coord: 395..623
score: 60.861
IPR016158Cullin homologySUPERFAMILY75632Cullin homology domaincoord: 391..664
NoneNo IPR availableGENE3D1.20.1310.10coord: 291..394
e-value: 3.0E-32
score: 110.2
NoneNo IPR availableGENE3D4.10.1030.10coord: 509..582
e-value: 2.1E-21
score: 74.8
NoneNo IPR availableGENE3D1.20.1310.10coord: 173..290
e-value: 7.0E-36
score: 122.3
NoneNo IPR availableGENE3D1.20.1310.10coord: 41..172
e-value: 4.3E-40
score: 136.7
NoneNo IPR availableGENE3D1.20.1310.10coord: 395..507
e-value: 1.8E-46
score: 156.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..27
IPR011991Winged helix-turn-helix DNA-binding domainGENE3D1.10.10.10coord: 652..752
e-value: 2.7E-35
score: 120.2
IPR011991Winged helix-turn-helix DNA-binding domainGENE3D1.10.10.10coord: 583..651
e-value: 5.7E-24
score: 83.5
IPR011991Winged helix-turn-helix DNA-binding domainSUPERFAMILY46785"Winged helix" DNA-binding domaincoord: 664..752
IPR001373Cullin, N-terminalPFAMPF00888Cullincoord: 54..653
e-value: 3.5E-211
score: 703.0
IPR016157Cullin, conserved sitePROSITEPS01256CULLIN_1coord: 725..752
IPR016159Cullin repeat-like-containing domainSUPERFAMILY74788Cullin repeat-likecoord: 47..392

Blast
BLAST of TCONS_00050380-protein vs. Swiss-Prot (Human)
Match: CUL4A (Cullin-4A OS=Homo sapiens GN=CUL4A PE=1 SV=3)

HSP 1 Score: 973 bits (2514), Expect = 0.000e+0
Identity = 471/722 (65.24%), Postives = 579/722 (80.19%), Query Frame = 0
Query:   31 TKRLVIKNFKSKPTLPSNYKEVTWEKLREAVVAIHNQQSISSSLEELYKAVENLCSHDMSMNLYDRLKNVCENYVKSIIKDFICDGMDNFMYLKKMNELWESHCRQMTMIRSIFLYLDRVYVLQHSTILSLWDVGLHLWRTHILGNNSIQTRTVDSLLFLIEKERNGEAVDGALLKSLLRMLADLQMYQDVFEERFLQATDLLYSAEGQRFMGEVDVPNYLKHVDKRLKEESDRLLHYLDIGTRKPLILCVENQLISKHITNILNKGFESLMDTNSSEHLNVMYALFSRVKDGQDKLCEYFGGYVKVKGLSIVQDVEKDKTMVQELLDFKEKLDNFIEGAFKKNEKFVSAMKDSFEVFINKRQNKPAELIAKFVDVKLKAGNKEASEEELEMRLDKIMILFRFIHGKDVFEAFYKKDLAKRLLLGKSASVDAEKSMLSKLKQECGSAFTSKLEGMFKDMELSKDIMNTFKQHISSQGDAPNIDLNVNILTMGYWPTYTPIEVNLPNEMVRLQEIFKTFYLSKHSGRKLQWQATLGSCGVKAVFEKSNHELHVSLFQTMCLLLFNDADELSYEDIRDATGIEENELKRTLQSLACGKLQSRVLKKKPPGKDINVKDRFFFNESFTLKLYRIKINQVQLKETAEENQLTNEQVFQDRQYQIDAAIVRILKTRKTLSHTLLVTELYNQLKFPVKPSDIKKRIESLIDRDYMERDKENTNTYVYVA 752
            +K+LVIKNF+ +P LP NY + TW KL EAV A+ +  SI  +LEELY+AVENLCSH +S  LY +L+  CE++V++ I  F  D +D+ ++LKK+N  W+ HCRQM MIRSIFL+LDR YVLQ+ST+ S+WD+GL L+RTHI+ +  +Q++T+D +L LIE+ER+GEAVD +LL+SLL ML+DLQ+Y+D FE +FL+ T+ LY+AEGQR M E +VP YL HV KRL+EE DR++ YLD  T+KPLI CVE QL+ +H+T IL KG + L+D N    L  MY LFSRV+ GQ  L +++  Y+K  G +IV + EKDK MVQ+LLDFK+K+D+ IE  F+KNE+FV+ MK+SFE FINKR NKPAELIAK VD KL+AGNKEA++EELE  LDKIMILFRFIHGKDVFEAFYKKDLAKRLL+GKSASVDAEKSMLSKLK ECG+AFTSKLEGMFKDMELSKDIM  FKQH+ +Q D+  IDL VNILTMGYWPTYTP+EV+L  EM++LQE+FK FYL KHSGRKLQWQ TLG   +KA F++   E  VSLFQT+ LL+FN+ D  S+E+I+ ATGIE++EL+RTLQSLACGK  +RVL K P GK++   D+F FN  F  KL+RIKINQ+Q+KET EE   T E+VFQDRQYQIDAAIVRI+K RKTL H LLV+ELYNQLKFPVKP D+KKRIESLIDRDYMERDK+N N Y YVA
Sbjct:   40 SKKLVIKNFRDRPRLPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGK--ARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 759          
The following BLAST results are available for this feature:
BLAST of TCONS_00050380-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CUL4A0.000e+065.24Cullin-4A OS=Homo sapiens GN=CUL4A PE=1 SV=3[more]
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