TCONS_00050382-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00050382-protein
Unique Name	TCONS_00050382-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	866

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00050382-protein ID=TCONS_00050382-protein|Name=TCONS_00050382-protein|organism=Clytia hemisphaerica|type=polypeptide|length=866bp
MAMNNLYGSTMSLDCGGNLKSSFNQSTLSLISVNTTTSSISTKVHDFNTK
DFVFCLTNKSLMQNKDLMAAIQYFKPEYTLVDTDENLEVMSNERRKYFFV
CQNFDDERFKTLRRKKCRICGPPLLVYLHSRKRALPDTSRPLFNGSMFGV
AVCFTGFASKGNMVNQLADLVHFMGGSVRRDFSGKITHLVANLAQGQKYK
NAVNLGKHIMTDGWVLEAWEKRHTSSFKASESSFVNSFNMKPFHGLKISF
LGFSPDETEHMQDITLQNDGHFVPVGEDGCTHLVIEESYSLDLTTESVKA
TFVVKQEWFWASIQLDVCAEENMYSYIDDKGTPLGTGSQRRFKRKHCNMS
GLSDLLSPGSPFFISNKRQSRDGALSSLSSATFDSSMGSPLAMIDSPIVK
ETKKEISARQQKCLELQHTERNYVTILQTIIKVFKEPLEQSANQRGGALL
ASEEIKTIFGAIPDLLDVHEKLFASINHLVDNWHEEQLIGKAITDCAEGM
MKAYPGFVNYFEFIKETINRCDKERPRFHAFLKLSMTNPDCQRQTLTELL
IRPVQRLPSMSLLMDDIFKHTKENNPDHAYVNDARAAVKKVLTFINEDKR
KTETQVQMFEILGEIENCPPYLLSAKRSLISKVDLMEVTEGLILKCEHLT
MFLFNDCIEIAKKKNRGVNSMTYKSPAIQNIQRGNVQKKSYDHMEFIEAR
HLKHVVDIKDDTDFKEMFGLIHLSNITQADQLSIFKMVPGTTKAEWINKV
VQRLKSSKATADAENLLMGVEPWELLSDKSDTSQEKERSGSLSKVFKKAK
SGITKKVVRALSQNKTPKSHNKSTLRRAMANVTPNTYPSTPGNTSGLVSP
TPSEYTIMDFSVCEEK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_031904	XLOC_031904	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00050382	TCONS_00050382	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000219	DH-domain
IPR001357	BRCT_dom
IPR011993	PH_dom-like
IPR001331	GDS_CDC24_CS

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005085	guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035556	intracellular signal transduction
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005085	guanyl-nucleotide exchange factor activity
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000219	Dbl homology (DH) domain	SMART	SM00325	RhoGEF_3	coord: 412..597 e-value: 4.9E-47 score: 172.2
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 415..596 e-value: 7.6E-38 score: 130.5
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 408..598 score: 30.421
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 393..615
IPR001357	BRCT domain	SMART	SM00292	BRCT_7	coord: 240..316 e-value: 0.001 score: 28.3 coord: 140..222 e-value: 2.5E-10 score: 50.3
IPR001357	BRCT domain	GENE3D	3.40.50.10190		coord: 150..223 e-value: 1.5E-14 score: 53.6
IPR001357	BRCT domain	PFAM	PF12738	PTCB-BRCT	coord: 151..214 e-value: 5.9E-12 score: 45.3
IPR001357	BRCT domain	PFAM	PF00533	BRCT	coord: 238..313 e-value: 2.6E-4 score: 21.2
IPR001357	BRCT domain	GENE3D	3.40.50.10190		coord: 228..331 e-value: 9.9E-15 score: 53.9
IPR001357	BRCT domain	PROSITE	PS50172	BRCT	coord: 149..222 score: 12.561
IPR001357	BRCT domain	PROSITE	PS50172	BRCT	coord: 238..326 score: 9.5
IPR001357	BRCT domain	CDD	cd00027	BRCT	coord: 149..220 e-value: 2.93328E-9 score: 53.8647
IPR001357	BRCT domain	SUPERFAMILY	52113	BRCT domain	coord: 196..325
IPR001357	BRCT domain	SUPERFAMILY	52113	BRCT domain	coord: 101..223
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 617..757 e-value: 7.2E-7 score: 28.6
None	No IPR available	GENE3D	1.20.900.10		coord: 407..616 e-value: 5.3E-51 score: 172.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 832..851
None	No IPR available	CDD	cd00160	RhoGEF	coord: 409..596 e-value: 5.89663E-37 score: 137.044
IPR001331	Guanine-nucleotide dissociation stimulator, CDC24, conserved site	PROSITE	PS00741	DH_1	coord: 546..571

Blast

[Close]

BLAST of TCONS_00050382-protein vs. Swiss-Prot (Human)
Match: ECT2 (Protein ECT2 OS=Homo sapiens GN=ECT2 PE=1 SV=4)

HSP 1 Score: 546.584 bits (1407), Expect = 0.000e+0
Identity = 303/774 (39.15%), Postives = 449/774 (58.01%), Query Frame = 0

Query:   78 YTLVDTDENLEVMSNERRKYFFVCQNFDDERFKTLRRKKCRICGPPLLVYLHSRKRALPDTSRPLFNGSMFGVAVCFTGFASKGNMVNQLADLVHFMGGSVRRDFSGKITHLVANLAQGQKYKNAVNLGKHIMTDGWVLEAWEKRHTSSFKASESSFVNSFNMKPFHGLKISFLGFSPDETEHMQDITLQNDGHFVPVGEDGCTHLVIEESYSLDLTTESVKATFVVKQEWFWASIQLDVCAEENMYSY-------------IDDKGTPLGTGSQRRFKRKHCNMSGLSDLLSPGSPFFISNKRQSRDGALSSLSSATFDSSMGSPLAMIDSPIVKE--------TKKEISARQQKCLELQHTERNYVTILQTIIKVFKEPLEQSANQRGGALLASEEIKTIFGAIPDLLDVHEKLFASINHLVDNWHEEQLIGKAITDCAEGMMKAYPGFVNYFEFIKETINRCDKERPRFHAFLKLSMTNPDCQRQTLTELLIRPVQRLPSMSLLMDDIFKHTKENNPDHAYVNDARAAVKKVLTFINEDKRKTETQVQMFEILGEIENCPPYLLSAKRSLISKVDLMEVTEGLILKCEHLTMFLFNDCIEIAKKKNRGVNSMTYKSPAIQNIQRGNVQKKSYDHMEFIEARHLKHVVDIKDDTDFKEMFGLIHLSNITQADQLSIFKMVPGTTKAE-WINKVVQRLKSSKATADAENLLMGVEPWELLSDKSDTSQEKERSGSLSKVFKKAKSGITKKVVRALSQNKTPKSHNKSTLRRAM 829
            +  +++ E  E + +   +  FV  +F D  F  L +  CR+ GPP+++    +   LP + RPL+  SM  + +CFTGF  K  +V +L  LVH MGG +R+DF+ K+THLVAN  QG+K++ AV+LG  IM   W+ +AWE+R+   F A+   F N F + PF    +SFLGFS +E  +M+++T    G ++P+G++ CTHLV+EE+   DL  E  K  +VVKQEWFW SIQ+D  A E MY Y             +    TP     +RR K     +S  +D+ SP  P     KR S + +LS  S     ++  S +   D+P               + SAR Q   EL  TE NYV IL TII++F+ PLE+   QRGG +LA EEIKTIFG+IPD+ DVH K+   +  L+ NW E + IG      ++ ++K YP FVN+FE  KETI +C+K++PRFHAFLK++   P+C RQ+L ELLIRPVQRLPS++LL++D+ KHT + NPD + +  A  ++K+V+T INEDKRKTE Q Q+F+++ E++ CP  LLS+ RSL+ +V+ + + E    + E +T+FLFNDC+EIA+K+++ +   T++SP  Q     +++     H+  +    +K V+DI++  D    F L+      QA+ L  F+M       E W+  + + + ++   ADAENL+   +P     +  D      R+   S+  KK     +KKV RA S +KTP    K  LRRA+
Sbjct:  107 FVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLVLCFTGFRKKEELV-RLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKYLPLGDERCTHLVVEENIVKDLPFEPSKKLYVVKQEWFWGSIQMDARAGETMYLYEKANTPELKKSVSMLSLNTPNSNRKRRRLKETLAQLSRETDV-SPFPP----RKRPSAEHSLSIGSLLDISNTPESSINYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEG-QRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIG--TFRSPHGQTRPPASLK-----HIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDSTLSRA---SRAIKKT----SKKVTRAFSFSKTP----KRALRRAL 855

The following BLAST results are available for this feature:

BLAST of TCONS_00050382-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00050382-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ECT2	0.000e+0	39.15	Protein ECT2 OS=Homo sapiens GN=ECT2 PE=1 SV=4	[more]

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TCONS_00050382-protein (polypeptide) - C. hemisphaerica