TCONS_00051574-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00051574-protein
Unique NameTCONS_00051574-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length406

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00051574-protein ID=TCONS_00051574-protein|Name=TCONS_00051574-protein|organism=Clytia hemisphaerica|type=polypeptide|length=406bp
EVITLYPTEWPAFIEIFLVRLENFLFIGEVQVEMAEEGKPQTKRLENIEN
NGFGPLPKARGMRDTILFSLLVLLVYLSSAAVYRNFYQGKRALLSQDVGD
AFVILFGICLGELLRSIVLYGEEKNHTVSRYSNSHWRALQACVPYSWKQI
CVFKIIFLVISFCGTAVYWIFAEKVSFNAFHLLSITVFSAINQVVLSKAE
VSHLNETENKHVADGLAWSYYFGYLKIMLPGMKGMLALAQGDEYKIDGED
IRDKLSSEKLHIVIPKNCYTYDSFKEVDKRITFKCSMPPIKKTRGGVQER
VYKNTVWEVKLEDDEEPLYVLMEYATPVLSMYDMKKEESAHFHGQDLEDQ
VKEFTTKLQKILDEDEECKNKYEIVLCGDVKSQKLSEIMRRTIQKEKENK
EKDKNI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032667XLOC_032667Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00051574TCONS_00051574Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR029158STING
IPR033952STING_C
Vocabulary: Biological Process
TermDefinition
GO:0032481positive regulation of type I interferon production
GO:0002218activation of innate immune response
Vocabulary: Molecular Function
TermDefinition
GO:0035438cyclic-di-GMP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0002218 activation of innate immune response
biological_process GO:0032481 positive regulation of type I interferon production
molecular_function GO:0035438 cyclic-di-GMP binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 394..406
NoneNo IPR availableCOILSCoilCoilcoord: 344..364
IPR029158Stimulator of interferon genes proteinPFAMPF15009TMEM173coord: 103..395
e-value: 1.6E-65
score: 221.0
IPR033952Stimulator of interferon genes protein, C-terminalCDDcd12146STING_Ccoord: 212..394
e-value: 6.88325E-52
score: 172.474

Blast
BLAST of TCONS_00051574-protein vs. Swiss-Prot (Human)
Match: STING (Stimulator of interferon genes protein OS=Homo sapiens GN=TMEM173 PE=1 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 2.335e-33
Identity = 86/286 (30.07%), Postives = 144/286 (50.35%), Query Frame = 0
Query:  121 GEEKNHTVSRYSNSHWRALQACV--PYSWKQICVFKIIFL--VISFCGTAVYWIFAEKVSFNAFHLLSITVFSAINQVVLSKAEVSHLNETENKHVADGLAWSYYFGYLKIMLPGMKGMLALAQGDEYKIDGEDIRDKLSSEKLHIVIPKNCYTYDSFKEVDKRITFKCSMPPIKKTRGGVQERVYKNTVWEVKLEDDEEPLYVLMEYATPVLSMYDMKKEESAHFHGQDLEDQVKEFTTKLQKILDEDEECKNKYEIVL---CGDVKSQKLS-EIMRRTIQKEKE 398
             EE  H  SRY  S+WR ++AC+  P     + +  I F   + +  G    W+ A      A ++L       +    L+ AE+S + E  N +VA GLAWSYY GYL+++LP ++     A+   Y     ++     S++L+I++P +C   D+    D  I F   +P       G+++RVY N+++E+ LE+ +     ++EYATP+ +++ M +   A F  +D  +Q K F   L+ IL +  E +N   ++      D  S  LS E++R   Q+EKE
Sbjct:   67 AEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWMLALLGLSQALNIL-------LGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQ-----ARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYEL-LENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKE 339          
The following BLAST results are available for this feature:
BLAST of TCONS_00051574-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
STING2.335e-3330.07Stimulator of interferon genes protein OS=Homo sap... [more]
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