TCONS_00052339-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00052339-protein
Unique NameTCONS_00052339-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1838

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00052339-protein ID=TCONS_00052339-protein|Name=TCONS_00052339-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1838bp
MEASKTLANKDVTKKSGLAVSGRGVVSFEENSNDKDKILKYDKKRNHSSP
SLARGLEVIVPSLKPSKTADQVSFDNINNSSPHMVSNSYVLTASEDENEP
ETVTSGGYFSARKAASTRKTSFERRGTINTINTNLDEDDEESDSDFGILR
NLTDDAFDKYYRRKIWFLILIRACCIASVVSVCMNTPQTFKMHPQLRKIT
LTIDIVTGFILGCEAVIKILHKGFVRGKKSYLRSAGRIFELVMVLCILIS
IGVQSYEMTLDISVIEQKVNNEYLKYSFLRAPRPLLLLRVMKSMLNLSLP
KTVSYRSMKQIWGVFLFTCYFVLLAGLLGIQMFGLMNFYCVKNGTDPGKV
QQTDLLIPSTRCPPPGYENNNFTCPTGFVCRNLTFEKFHTNERPFEHILA
GLLTVYEASSMEGWSAIMYAGMDIRFWMFSFLYSLALIIFVSILVKNVFI
AIITEAFADLRLQVSKLSSHVNQPKETGDESKVLRRSEEHMSLVNRNEDL
RRNYARQVIAKITRSGAFQFVILLCVLADAIIQSFFFKAEFAKYIQIVFT
LLFLIETILKMIGLGRKQYFQSAQCVFEFILCVGSTVFLAPVFMGRTGFV
VFQVMRPFRLVLVWSTLRSFLKRILGSGSKIGSLILFTLAALVIAAGISL
QVFCGTGLPSVPDDTYSFSTFPQAIKSLFQIFMTEAWAEIMDDVLYRGGL
GFAFLVFILFILFHFLAATILISVFVALILDNLELEEDVKIAKQRRMGEE
VADTQEKLPARMRLYQNLKPRPKLTKIDYVETPLPKLRQSFVSNYVEMGE
EMDEEVPVITNSNLRYNKITEPTANDSLPLNFIENQPMESSSLHQFRKQS
SVTTLMQDALNKRMSISHHGNGTVKKRQKTLTKSFRSGLSRHLSGQSAGS
RRVRDTTPSTPVSRVSSNQSATRKTYSQNRRISTNTMDRAKDIDVGLVRQ
KLEEAQRKKESQIEQLRENHPLFDKSLFIFSAKNPIRKFVQKIVHSRYNA
QKDEKTGHLGGFSPERLKRYFASQTWLDWIVLFFTQVSIGAMFWESPSHR
TFDSEAMKIIEYIFVVTTSIELTLKIISDGLILSPNALIRDFGNIIHVFI
YIVSLIYIAWKPEVIPPGSAQQIILVLRALRPLRLITLAPPLRKVVTVLV
SGYKAIIKVAILQLALMFVFASYGVQFLSGELEKCNDGSITTKANCTGVF
LMKIATPNDFTNLSGRQVRILVPRVWRNPKSFNFDHMGNALLTLMEILSL
EGWTEVRDIIEDKFGFFGSLYPHVYVFFASLIGLTLFIGVIVSNFNENKG
TALLTVEQKRWKDLKKKILLAQPLHLPGRPPADTLRYKMYEIFIGKTYNR
CYGILILINCGMLCYGQWVPTERDDSIINSLTYVSIVCCMLFTIDTLLKI
YIFQWSGYWLSWRNRFDFLLMICGLIFSLWNIASCHGVAQDEASCNYSKQ
FGVAVFILRYVSLSGKHNILRMLMLTVVISLTKSFYTIAVLVCIMFCYAF
VGVILFGSVKPGLAITRNVNFTTSYYAFLLLFRVATGEDWNQIMHDAMIT
KPYCTELPNENYWESTCGNPTSALIYFHSYYLIISYIFLNLFIAVVIENF
SIFYSTDDDPIMSQQDIQCFQETWNLCDEEKSGSMSLVRAKVVLRLLQGG
LALDKLKIGRPLIFRRMVAELEKVKTQKKVTFHNLLFVIAYNKIDFSTSL
QLDERLTREELEGTILEEVATETIKEWITMIIEKRRKEKKPKSTLQRRFS
GLSSNSLNSVDSLDSDRGGDDLNASTLSLSAHPSPKLGALSPASSYETSG
YEPQASLRQRKLTNDRTKEKNDEFYSWWGENVAVKGNK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033093XLOC_033093Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00052339TCONS_00052339Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR005821Ion_trans_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
Vocabulary: Biological Process
TermDefinition
GO:0055085transmembrane transport
GO:0006811ion transport
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016020 membrane
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 945..969
NoneNo IPR availableGENE3D1.10.287.70coord: 1345..1605
e-value: 3.7E-27
score: 94.6
coord: 1023..1298
e-value: 7.7E-30
score: 103.4
coord: 163..462
e-value: 1.2E-25
score: 89.7
coord: 514..735
e-value: 1.6E-23
score: 82.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 863..938
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1774..1818
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 518..734
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 1230..1297
coord: 1025..1181
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 160..336
coord: 391..458
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 1348..1601
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 517..734
e-value: 2.8E-27
score: 95.4
coord: 1350..1605
e-value: 7.9E-31
score: 107.1
coord: 1025..1298
e-value: 6.0E-37
score: 127.1
coord: 166..461
e-value: 8.1E-26
score: 90.6

Blast
BLAST of TCONS_00052339-protein vs. Swiss-Prot (Human)
Match: NALCN (Sodium leak channel non-selective protein OS=Homo sapiens GN=NALCN PE=1 SV=1)

HSP 1 Score: 1100.12 bits (2844), Expect = 0.000e+0
Identity = 632/1690 (37.40%), Postives = 981/1690 (58.05%), Query Frame = 0
Query:  144 SDFGILRNLTDDAFDKYYRRKIWFLILIRACCIASVVSVCMNTPQTFKMHPQLRKITLTIDIVTGFILGCEAVIKILHKGFVRGKKSYLRSAGRIFELVMVLCILISIGVQSYEMTLDISVIEQKVNNEYLKYSFLRAPRPLLLLRVMKSMLNLSLPKT----VSYRSMKQIWGVFLFTCYFVLLAGLLGIQMFGLMNFYCVKNGTDPGKVQQTDLLIPSTRCPPPGYENNNFTCPTGFVC---RNLTFEKFHTNERPFEHILAGLLTVYEASSMEGWSAIMYAGMDIRFWMFSFLYSLALIIFVSILVKNVFIAIITEAFADLRLQVSKLSSHVNQPKETGDESKVLRRSEEHMSLVNRNEDLRRNYARQVIAKITRSGAFQFVILLCVLADAIIQ-SFFFKAEFAK------YI-QIVFTLLFLIETILKMIGLGRKQYFQSAQCVFEFILCVGSTVFLAPVFMGRTGFVVFQVMRPFRLVLVWSTLRSFLKRILGSGSKIGSLILFTLAALVIAAGISLQVFCGTGLPSVPDDTYSFSTFPQAIKSLFQIFMTEAWAEIMDDVLYRGGLGFAFLVFILFILFHFLAATILISVFVALILDNLELEEDVKIAKQRRMGEEVADTQEKLPARMRLYQNLKPRPKLTKIDYVET--PLPKLRQSFVSNYVEMGEEMDEEVPVITNSNLRYNKITEPTANDSLPLNFIENQPMESSSLHQFRKQSSVTTLMQDALNKRMSISHHGNGTVKKRQKTLTKSFRSGLSRHLSGQSAGSRRVRDTTPSTPVSRVSSNQSATRKTYSQNRRISTNTMDRA----------KDIDVGLVRQKLEEAQRKKESQIEQLRENHPLFDKSLFIFSAKNPIRKFVQKIVHSRYNAQK-DEKTGHLGGFSPERLKRYFASQTWLDWIVLFFTQVSIGAMFWESPSHRTFDSEAMKIIEYIFVVTTSIELTLKIISDGLILSPNALIRDFGNIIHVFIYIVSLIYIAWKPEVIPPGSAQQIILVLRALRPLRLITLAPPLRKVVTVLVSGYKAIIKVAILQLALMFVFASYGVQFLSGELEKCNDGSITTKANCTGVFLMKIATPNDFTNLSGR----QVRILVPRVWRNPKSFNFDHMGNALLTLMEILSLEGWTEVRDIIEDKFGFFGSLYPHVYVFFASLIGLTLFIGVIVSNFNENKGTALLTVEQKRWKDLKKKILLAQPLHLPGRPPADTLRYKMYEIFIGKTYNRCYGILILINCGMLCYGQWVPTERDDSIINSLTYVSIVCCMLFTIDTLLKIYIFQWSGYWLSWRNRFDFLLMICGLIFSLWNIASCHGVAQDEASCNYSKQFGVAVFILRYVSLSGKHNILRMLMLTVVISLTKSFYTIAVLVCIMFCYAFVGVILFGSVKPGLAITRNVNFTTSYYAFLLLFRVATGEDWNQIMHDAMITKPYCTELPNE-NYWESTCGNPTSALIYFHSYYLIISYIFLNLFIAVVIENFSIFYSTDDDPIMSQQDIQCFQETWNLCDEEKSGSMSLVRAKVVLRLLQGGLALDKLKIGRPLIFRRMVAELEKVKTQKKVTFHNLLFVIAYNKIDFSTSLQLDERLTREELEGTILEEVATETIKEWITMIIEKRRKEKKPKSTLQRRFSGLSSNSLN---SVDSLDSDRGGDDLNASTLSLSAHP--SPKLGALSPASS 1795
            +DFG   +L+D+A D  +  K W   L+R C I SV+SVCMNTP TF+ +P L+ +T T+D +  F+   E + K+  +G V+G  SY++    +F+  MV C+ +S+ +Q +E+          + ++   +  LR PRPL+++R  +      LP+T    +  RS +QIW V +F  +F+LL G+LG+QMFG   ++CV N T PG V    L IP T C P   E   + CP GF C    +L   +       F  I   + TVYEA+S EGW  +MY  +D      S+ Y + LI F++ LVKNVFIA+I E FA++R+Q  ++    +    T         +     LV  + +  +  A   + K+ RS  F   IL  V  D I+  S ++K E  +      Y+ ++ FT+LF +E +LK+  LG   Y  S+   FE +L +G+T+ + P  +  + F  FQV+R  RL+ +   L  F+ +I G G K+GSL++FT + L++ + ISLQ+FC        ++   F+TFP+A  S+FQI   E W ++MD  L   G  +A +V I FIL+H  A  IL+S+FVA+ILDNLEL+ED+K  KQ +  E  ADT+EKLP R+R+++    RP++ KI  + +   +PK+R+SF+  +++  ++        T   LR    T  ++ D    + IE    ++  + Q  ++S  +   ++ L K  +++         RQ+ L+ SF         GQ A  R +          R S    +  +  S+ + + T T D +          +D ++ ++++K E+A+ K++ Q E+LRENHP FDK LFI   ++  R F + +V +R+NA K D  TG +      +L       T+LDW+++  T  S  +M +ESP  R   +  ++I EY+FV+  SIEL LKI++DGL  +P A+IRDFG ++ +FIY+VSLI++ W P+ +P  S  Q+++VLR LRPLR+  L P +RKVV  L SG+K I  V+IL L LM VFAS+GVQ  +G+L KCND +I  + +C G+F + ++   +  NL  R    +    VPRVW NP++FNFD++GNA+L L E+LSL+GW EVRD+I  + G    +Y HV+VF   +IGLTLF+GV+++NFNENKGTALLTV+Q+RW+DLK ++ +AQPLHLP RP  D  R KMY+I     + R   +L+L    +L     V  + +D +   L  +S+V   +F ++  +KI     +G+W S RNR+D L+   G+++ + + A  +          Y+   G  V + R+ S+ GKH  L+ML+LTVV+S+ KSF+ I  +  ++ CYAF GV+LFG+VK G  I R+ NF+++  A  +LFR+ TGEDWN+IMHD M+  P+CT  P+E  YW + CGN   AL+YF S+Y+II+YI LNL +A+++ENFS+FYST++D ++S  D++ FQ  WN+ D+++ G +   R K +LRLL+G L +D  K    L+F+ M  E+E++     VTFH++L +++Y  +D   SLQL+E L RE+LE TI EEVA +TI+ W+   +++ R +++   ++           L+   +  S+++ +  +D NA++   S  P  S +   LSP  S
Sbjct:   16 TDFGPDESLSDNA-DILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIA--------DIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEG--YQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPD-LYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFV------EELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQ-------DTCCLLRSLPTTSSSSCDHSKRSAIE----DNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACT--RQRMLSGSF--------EGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNL-NLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLS----VKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNA---------YTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCT--PDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDK--DKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDTNANSQDNSMQPETSSQQQLLSPTLS 1648          
The following BLAST results are available for this feature:
BLAST of TCONS_00052339-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NALCN0.000e+037.40Sodium leak channel non-selective protein OS=Homo ... [more]
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