TCONS_00052911-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00052911-protein
Unique NameTCONS_00052911-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length514

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00052911-protein ID=TCONS_00052911-protein|Name=TCONS_00052911-protein|organism=Clytia hemisphaerica|type=polypeptide|length=514bp
KFENLILEDLLVMMTKQTILLCLILMICLMLCAAQPTPPATSSEGRLLKF
IFQDYNPNARPVVRPTDSVSLKYDIALKQILEINEREQVITTNVWIRHYW
TDPLLRWNPSDWNGTAYVAVSPDTIWKPDITLYNNAEREFQGFDAFGKTR
VTIYSDGSCVWLLPIILRSQCKMNLLYFPFDEQYCPLVFGSWAYDGGALN
LTNRSPEGDLSSFSESGEFNIGPMKAVKHTTLYGCCPNPYYTIEYTVHMI
RRAKFYLFNLVIPGVLIALLTIFSFFLPPLCGERTGLIITNFLSLSVYIL
MVSDNVPPSSNIPLLVEFYTILISEIGIALILNCMIIPLAARNTPMPYII
KKIFLQKLAYVTLCRRPDDVRIDKIQNENNEDKLFNNGYLNSTFNENIIF
ANNKHVVTSNGKIMTGDHKQNGNHGYHNLMNNAAPMLRERRVIKVASADE
PLYEMSDKLSAIHDIMKDDVSEKKNSSDWEQLTLVLDRFFFAIFFVTIFV
SVGAILGKAPKITM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033430XLOC_033430Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00052911TCONS_00052911Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR002394Nicotinic_acetylcholine_rcpt
IPR006029Neurotrans-gated_channel_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO:0045211postsynaptic membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0022848acetylcholine-gated cation-selective channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0045211 postsynaptic membrane
molecular_function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 171..185
score: 51.31
coord: 124..135
score: 51.06
coord: 247..259
score: 25.93
coord: 91..107
score: 41.15
IPR002394Nicotinic acetylcholine receptorPRINTSPR00254NICOTINICRcoord: 112..126
score: 22.3
coord: 78..94
score: 38.95
coord: 151..169
score: 36.14
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 260..500
e-value: 4.4E-25
score: 89.0
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 255..511
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 45..252
e-value: 1.4E-56
score: 191.2
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 39..256
e-value: 1.3E-67
score: 226.9
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 43..252
NoneNo IPR availableGENE3D1.20.58.390coord: 257..507
e-value: 5.7E-31
score: 106.7
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 171..185

Blast
BLAST of TCONS_00052911-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 255.373 bits (651), Expect = 7.450e-79
Identity = 148/477 (31.03%), Postives = 248/477 (51.99%), Query Frame = 0
Query:   40 ATSSEGRLLKFIFQDYNPNARPVVRPTDSVSLKYDIALKQILEINEREQVITTNVWIRHYWTDPLLRWNPSDWNGTAYVAVSPDTIWKPDITLYNNAEREFQGFDAFGKTRVTIYSDGSCVWLLPIILRSQCKMNLLYFPFDEQYCPLVFGSWAYDGGALNLTNRSPEGDLSSFSESGEFNIGPMKAVKHTTLYGCCPNPYYTIEYTVHMIRRAKFYLFNLVIPGVLIALLTIFSFFLPPLCGERTGLIITNFLSLSVYILMVSDNVPPSS-NIPLLVEFYTILISEIGIALILNCMIIPLAARNTP----MPYIIKKIFLQKLAYVTLCRRPDDVRIDKIQNENNEDK---LFNNGYLN-STFNENIIFANNKHVVTSNGKIMTGDHKQNGNHGYHNLMNNAAPMLRERRVIKVASADEPLYEMSDKLSAIHDIMKDDVSEKKNSSDWEQLTLVLDRFFFAIF-FVTIFVSVGAIL 506
            A+ +E RL + +F+DYN   RPV   +D V + +++++ Q+++++E  Q++ TN+W++  W D  L+WNPSD+ G  ++ V    IWKPDI LYNNA  +FQ  D   KT+  +   G   W+ P I +S CK+++ YFPFD Q C + FGSW+YD   ++L       +L  + ESGE+ I      KH   Y CC   Y  I Y++++ R   FY  NL+IP +LI+ LT+  F+LP  CGE+  L I+  LSL+V++L++++ +P +S  IPL+ E+    +  + +++++   ++ +  R TP    MP  +K +FL  L  V    RP         NE N  K   L+     N + F+        +     +G      H++     +   +  ++       V+ +++    + E    +  I + MK     K+   DW+ + +V+DR F  +F  V I  + G  L
Sbjct:   31 ASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDD---KTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYR-TPTTHTMPSWVKTVFLNLLPRVMFMTRP-------TSNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFL 496          
The following BLAST results are available for this feature:
BLAST of TCONS_00052911-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA37.450e-7931.03Neuronal acetylcholine receptor subunit alpha-3 OS... [more]
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