TCONS_00054287-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00054287-protein
Unique NameTCONS_00054287-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length586

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00054287-protein ID=TCONS_00054287-protein|Name=TCONS_00054287-protein|organism=Clytia hemisphaerica|type=polypeptide|length=586bp
MICSRVMNHSTTGLVASNHNVTSDIDFGIDKDVTLIEDNREYNPVVFDVL
KVSADEIAQQLTLIDLPLFQHVEPEELTSCSWTSKRKHDNCPNIVKATKR
FNQVSYWVTREILDTNTAKGRAERIAYFIKVAKKLQELNNLNCLKAVVSG
LQCTPIYRLNKTWNVVPKRDKEKLEKLNELVCEENNSSKLRLHLQTTKLP
CIPYLGMYLTDLTYINTIHPPTGGLDVERTNKMNEILRIIADYQQSLYDF
KPIYAVQNYLNSVKYIDELQKFMEDENYKLSCQIEPTELQTRAERNGSTG
KRETVSESDDTYRLYPKQPASKSNSLNPRRTGSSINPKSASLNLPSTPFN
QHRSPSPNRKDFVPGHRKVKSLGSTQIFLQSISGMNPSSTSISSGSNVST
GSRYNLVDDSILEDNLNTDIRSSTSYDSGLDHDEPETHPIIRSNYISEDT
KPEFYFKLQGFLKRKTLKRNATSPKVANWQRYWVGITCSHLVYFLPKYRA
FGGHDRNNFKENAEKILPLFGSDVCECNEEGSFQLTDESGANVYRFRAGT
NLNRKLWMDFIKEASNGGMKEPPQNLITFDDDDTHL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034238XLOC_034238Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00054287TCONS_00054287Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001849PH_domain
IPR001895RASGEF_cat_dom
IPR011993PH_dom-like
IPR023578Ras_GEF_dom
Vocabulary: Biological Process
TermDefinition
GO:0007264small GTPase mediated signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005085guanyl-nucleotide exchange factor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007264 small GTPase mediated signal transduction
molecular_function GO:0005085 guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 456..568
e-value: 6.0E-8
score: 42.4
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 458..565
e-value: 1.4E-5
score: 25.4
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 455..566
score: 10.873
IPR001895Ras guanine-nucleotide exchange factors catalytic domainSMARTSM00147RasGEF_3coord: 49..288
e-value: 2.3E-80
score: 283.0
IPR001895Ras guanine-nucleotide exchange factors catalytic domainGENE3D1.10.840.10coord: 42..313
e-value: 1.7E-78
score: 263.1
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPFAMPF00617RasGEFcoord: 56..220
e-value: 8.5E-53
score: 179.1
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPROSITEPS50009RASGEF_CATcoord: 53..287
score: 62.09
IPR001895Ras guanine-nucleotide exchange factors catalytic domainCDDcd00155RasGEFcoord: 49..283
e-value: 5.15452E-62
score: 205.564
IPR011993PH domain-likeGENE3D2.30.29.30coord: 446..569
e-value: 6.1E-8
score: 32.0
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 458..576
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 289..364
IPR023578Ras guanine nucleotide exchange factor domainSUPERFAMILY48366Ras GEFcoord: 44..288

Blast
[Close]
BLAST of TCONS_00054287-protein vs. Swiss-Prot (Human)
Match: RGPS2 (Ras-specific guanine nucleotide-releasing factor RalGPS2 OS=Homo sapiens GN=RALGPS2 PE=1 SV=1)

HSP 1 Score: 356.295 bits (913), Expect = 6.426e-116
Identity = 223/590 (37.80%), Postives = 325/590 (55.08%), Query Frame = 0 
Query:   37 EDNREYNPVVFDVLKVSADEIAQQLTLIDLPLFQHVEPEELTSCSWTSKRKHDNCPNIVKATKRFNQVSYWVTREILDTNTAKGRAERIAYFIKVAKKLQELNNLNCLKAVVSGLQCTPIYRLNKTWNVVPKRDKEKLEKLNELVCEENNSSKLRLHLQTTKL-PCIPYLGMYLTDLTYINTIHPPTGGL--DVERTNKMNEILRIIADYQQSL-YDFKPIYAVQNYLNSVKYIDELQKFMEDENYKLSCQIEPTELQTRAERNGSTGKRETVSESDDTYRLYPKQPASKSNSLNPRRTGSSINPKSASLNLPSTPFNQHRSPSPNRKDFVP-GHRKVKSLGSTQIFLQSISGMNPSSTSISSGSNVSTGSRYNLVDDSILEDNLNT---------------------DIRSSTSYDS----GLDHDEPETHPIIRSNYIS----------EDTKPEFY---FKLQGFLKRKTLKRNATSPKVANWQRYWVGITCSHLVYFLPKYRAFGGHDRNNFKENAEKILPLFGSDVCECNEEGS---FQLTDESGANVYRFRAGTNLNRKLWMDFIKEASNGGMKEPPQNLITFD 580
            E  + ++ VVFDVLKV+ +E A Q+TL+D+P+F+ ++P+EL+SC W  K K+ + PN V  T+RFN VS+WV REIL   T K RAE ++++IK AKKL ELNNL+ L AVVSGLQ  PI+RL KTW ++ ++DK   EKL  ++ +E+N  +LR ++ + K+ PCIPYLG+YL+DLTYI++ +P TG +  + +R+N MN ILRII+D QQS  YD   +  VQ YLNSV+YI+ELQKF+ED+NYKLS +IEP          G++  R   S  D    + P+  AS      P+    S+  + A L  P TP      PSP  ++ +P GHRK  SLG        I  MN  +    S +  + G R+ L+DDS++E +  +                     ++   TS+ +     L H       + R+ Y S          ED     Y     +QG L+RKTL +    P VA+W +YW  +  + L Y+  K  +    +R +FK  + K + + G  V   ++      F LTD    N Y+F+AG  +N  LW   +  A     ++ P NL+TF+
Sbjct:   33 ELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEP----------GTSTPRSAASRED---LVGPEVGAS------PQSGRKSVAAEGALL--PQTP------PSP--RNLIPHGHRKCHSLG-----YNFIHKMN--TAEFKSATFPNAGPRH-LLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAK--SLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE 583
The following BLAST results are available for this feature:
BLAST of TCONS_00054287-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RGPS26.426e-11637.80Ras-specific guanine nucleotide-releasing factor R... [more]
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