TCONS_00054845-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00054845-protein
Unique NameTCONS_00054845-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1275

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00054845-protein ID=TCONS_00054845-protein|Name=TCONS_00054845-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1275bp
MACLCNLIKDMKKIMRRILVVLMITPAIFQNFVLGDFQFVSKSWLAVPAI
PHIIHKSGKDFNIECITNEPKAVVTLEVRLENQNIFQNARTAFPGRLVEK
DQSFVIQRISDKDNGEYFCRATNSSQKISLNKGILDVRKPQNSDIDLYPD
TTELLIERGGDANITCEAYDPQGLPLSYLTWLKQPQDGSPVAVDSSRVSS
EGISNLDIEVLMFKNFELVRDGGVYICQRQDPKGDVSSKSITVNQKADAP
LQINLLGKTRVIEGSRLILTCQASGVPAPSVTQWFKDGKQQKSCDKEECV
LTVQSSQHPKDDGQYSCHTKNRYQQISKKINITILAPPLLEKFQKVHIAN
FDEEYQLTCSLTKNANPPPSITLQSQPNTCIKDETNCQPISGAWKLIKKE
VTQTKLLFIAPTTKSSIFYRCIAKNEVGNSSTTMLLTRKNKKDIQFGFLN
ENPHMVNEESPLNITCISDPFIYKNVSITTPSHLAFASFTPSVKTYTEDK
QRITTYYVKKAKLSMNGVFTCIGALVRTGELRKIHLNVTVKELKAPSVGF
VEKDLTISQDQNKNYLLDCQVSGNPQPDVIWKFSGSPITVKDDISSVEKC
ETHKKGFYSISGENDQLVICQLDYKKHEGVYECVASNKVGTPARAIVNLQ
ITAKPEITSILGDVTFRIDLEDQITCKAHGNPHPKVTWYRINQSNNRNST
ELTTHNRLATLNSTILQRYGSGVYKCLAKNSEGETSKGMNLTLITADKNT
QSADNLKEIFIGIALAFVLMIIFMICFILWYKRRLKKKHAAYLRPNANFV
LDPDRSLFDQSNELPYDMTWEFPQQKLTFIKSLGKGAFGEVWLAEAEGIT
EIDARDKSNEATKRRKRFRNEGGCLARLIGKNKKTNEGYQKTLVAVKTLK
DESDASQYKDLASELKILIHVGQHKNIVNLLGACTLEGKLRVILEFCFHG
NLLTFLRSKRDSYQDVWEKHKEDMSDEFTNVDMLKIALDIAKGMEFLESR
KCVHRDLAARNVLVSVDFTMKIGDFGLARDXDLAARNVLVSVDFTMKIGD
FGLARDLINDEFYLKQTSGLVPIKWMPPEAIKDKIYNSLTDVWSYGIVLW
EIYSLGGSPYPGLPAENLMKFLDSERRMECPDHCPISVYKVMLKCWSKVP
FNRPSFKEIKEELSSIMKENSPNYASQYIDLTPNDFEDGNVRQSRLYLEA
TDGDQEQYSDQHSNEDEHSCKRPLLDSGTLNGSAPNNRRSNGFEPAQIPL
LDSSNGVDYLNGDTPYDDNLRETHL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034546XLOC_034546Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00054845TCONS_00054845Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR003598Ig_sub2
IPR003599Ig_sub
IPR020635Tyr_kinase_cat_dom
IPR013783Ig-like_fold
IPR013098Ig_I-set
IPR008266Tyr_kinase_AS
IPR001824Tyr_kinase_rcpt_3_CS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0004714 transmembrane receptor protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 1071..1081
score: 59.89
coord: 944..957
score: 45.53
coord: 1134..1156
score: 45.7
coord: 1090..1112
score: 59.7
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 827..1031
e-value: 1.5E-43
score: 148.9
coord: 1032..1163
e-value: 1.4E-48
score: 165.3
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 157..234
e-value: 0.17
score: 14.6
coord: 670..733
e-value: 0.16
score: 14.8
coord: 56..126
e-value: 0.076
score: 17.8
coord: 262..324
e-value: 3.3E-7
score: 40.0
coord: 560..640
e-value: 3.8E-5
score: 33.1
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 554..652
e-value: 5.1
score: 14.0
coord: 256..335
e-value: 0.0061
score: 25.8
coord: 451..541
e-value: 21.0
score: 8.6
coord: 344..439
e-value: 98.0
score: 2.9
coord: 661..744
e-value: 12.0
score: 10.7
coord: 50..138
e-value: 11.0
score: 11.2
coord: 151..246
e-value: 5.7E-4
score: 29.2
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 827..1163
e-value: 7.3E-120
score: 414.2
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 245..342
e-value: 1.5E-14
score: 53.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 45..157
e-value: 2.8E-7
score: 30.0
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 422..544
e-value: 0.017
score: 14.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 655..762
e-value: 2.8E-13
score: 49.4
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 545..654
e-value: 2.0E-14
score: 52.9
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 343..421
e-value: 7.5E-4
score: 19.2
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 158..244
e-value: 2.7E-7
score: 30.0
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 36..446
e-value: 2.0E-18
score: 63.9
coord: 885..977
e-value: 1.4E-26
score: 90.8
coord: 412..859
e-value: 1.3E-32
score: 110.9
coord: 1031..1230
e-value: 2.8E-54
score: 182.6
coord: 963..1031
e-value: 1.7E-20
score: 70.7
NoneNo IPR availablePFAMPF13927Ig_3coord: 259..321
e-value: 3.1E-10
score: 40.4
coord: 560..637
e-value: 1.1E-8
score: 35.4
NoneNo IPR availableGENE3D1.10.510.10coord: 1032..1227
e-value: 2.9E-32
score: 111.3
NoneNo IPR availableGENE3D1.10.510.10coord: 934..1031
e-value: 3.1E-23
score: 81.9
NoneNo IPR availableGENE3D3.30.200.20coord: 815..933
e-value: 1.5E-16
score: 59.8
NoneNo IPR availableCDDcd00096Igcoord: 62..129
e-value: 5.5655E-4
score: 38.6243
NoneNo IPR availableCDDcd00096Igcoord: 567..641
e-value: 6.8472E-8
score: 50.5655
NoneNo IPR availableCDDcd00192PTKccoord: 833..1163
e-value: 2.20544E-116
score: 364.553
NoneNo IPR availableCDDcd00096Igcoord: 267..331
e-value: 1.7518E-7
score: 49.4099
NoneNo IPR availableCDDcd00096Igcoord: 162..239
e-value: 0.00306127
score: 36.3131
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 655..742
e-value: 6.0E-10
score: 39.0
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 1002..1014
IPR001824Tyrosine-protein kinase, receptor class III, conserved sitePROSITEPS00240RECEPTOR_TYR_KIN_IIIcoord: 922..935
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 149..242
score: 9.646
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 546..652
score: 10.353
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 48..129
score: 7.25
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 655..742
score: 10.88
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 250..333
score: 13.276
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 52..138
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 560..657
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 331..437
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 646..743
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 250..334
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 154..244
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 827..1167
score: 38.252
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1032..1183
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 806..851
coord: 888..1030

Blast
[Close]
BLAST of TCONS_00054845-protein vs. Swiss-Prot (Human)
Match: FGFR3 (Fibroblast growth factor receptor 3 OS=Homo sapiens GN=FGFR3 PE=1 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 6.802e-89
Identity = 211/674 (31.31%), Postives = 312/674 (46.29%), Query Frame = 0 
Query:  569 CQVSGNPQPDVIWKFSGSPITVKDDISSVEKCETHKKGFYSISGENDQLVICQLDYKKHEGVYECVASNKVGT-------------PARAIVNLQITAKPEITSILG-DVTFRIDLEDQITCKAHGNPHPKVTWYRINQSNNR----NSTELTTHNRLATLNST-----ILQRYG-----SGVYKCLAKNSEGETSKGMNLTLITADKNTQSADNLKEIFIGI---ALAFVLMIIFMICFILWYKRRLKKKH--AAYLRPNANFVLDPDRSLFDQSN---------------------------ELPYDMTWEFPQQKLTFIKSLGKGAFGEVWLAEAEGITEIDARDKSNEATKRRKRFRNEGGCLARLIGKNKKTNEGYQKTLVAVKTLKDESDASQYKDLASELKILIHVGQHKNIVNLLGACTLEGKLRVILEFCFHGNLLTFLRSKRDSYQDVWEKHKEDMSDEFTNVDMLKIALDIAKGMEFLESRKCVHRDLAARNVLVSVDFTMKIGDFGLARDXDLAARNVLVSVDFTMKIGDFGLARDLINDEFYLKQTSGLVPIKWMPPEAIKDKIYNSLTDVWSYGIVLWEIYSLGGSPYPGLPAENLMKFLDSERRMECPDHCPISVYKVMLKCWSKVPFNRPSFKEIKEELSSIMKENSPNYASQYIDLT 1182
            C  +GNP P + W  +G            E    H+ G   +  +   LV+  +      G Y CV  NK G+             P R I+   + A    T++LG DV F         CK + +  P + W +  + N      + T   T  + A  N+T     +L  +      +G Y CLA NS G +     L ++ A++    AD    ++ GI    + F L I+ +    L   R   KK   +  +   + F L    SL   ++                           ELP D  WE  + +LT  K LG+G FG+V +AEA GI      DK   A                            +   VAVK LKD++      DL SE++++  +G+HKNI+NLLGACT  G L V++E+   GNL  FLR++R    D      +   ++ T  D++  A  +A+GME+L S+KC+HRDLAAR                          NVLV+ D  MKI DFGLARD+ N ++Y K T+G +P+KWM PEA+ D++Y   +DVWS+G++LWEI++LGGSPYPG+P E L K L    RM+ P +C   +Y +M +CW   P  RP+FK++ E+L  ++   S +   +Y+DL+
Sbjct:  176 CPAAGNPTPSISWLKNGR-----------EFRGEHRIGGIKLRHQQWSLVMESV-VPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQ--TAVLGSDVEFH--------CKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGI------DKDRAA----------------------------KPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAAR--------------------------NVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTD---EYLDLS 764
The following BLAST results are available for this feature:
BLAST of TCONS_00054845-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR36.802e-8931.31Fibroblast growth factor receptor 3 OS=Homo sapien... [more]
back to top