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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00057661-protein ID=TCONS_00057661-protein|Name=TCONS_00057661-protein|organism=Clytia hemisphaerica|type=polypeptide|length=2300bp QYIQNFYHEDPNAYKNEIQTISNMRKGIGNIPYDIQGCKTLRKYFTQLYY LQSRFPMLDGGEAAVPFIWFDVYSGEPVMYKDIRYEQACVLFNIGALYSH LAVREQRQTDESLKTAVQHFQSAAGAFQYLKDNYLLSECIDMTEDVLSLK IKIMLGQAVECILEKSILENKNPTTIARIAAQIVDTFNECINLFSKSGTS EMDPDVKKMWMKSLKVKIKSYETISYVYMSNDADHKEKYGEKVTYLKAAS DKIAEALKLSKSQTNETVNFIADVVQVKYEDAKKNNDFIYHMKIPDISEM DQIKGVDIVKPVPFLYNDKDVAGPDIFQRLVPMKAHEASSLYSDKKDTLL RSLVNEVEEKDVSLSQYLTAMKIEELLDPKENKLPDDLQDKNKFLQSNPD LIPKAEKLVEELAGLSSELDGLIKDSKVILDQEMRIDAQENSGREMGTLR EYDKKLTQCRDTHGEAQTVNMKLVQTIIEKKSMIEFLSGDPKNILASLPS LHVVDDSIDDALVQRIREILGKVDKMRTQRQSLMQTLRTEFDKDDVTAQL VVLKDGGNRQAFFDEQIKKHDKNIAYLRQNLSAQDNIIQALTEANAKYAV TREKELGCKGEFDREVNRYMNDIKLFLAFQDRIRSSGIPFFKELQKEVNA LHQKIVEFSNDRKKKRPSKSVANVAPAPSRPTARKPPLMGATSPTQIPNI NPITAIRPPFIPGANPTVGPHGALQRPPPQMNPNQLPGQPFRPQNPNLPL QNIANIRPNMTIGPGGGLQPQNMPPNRFPSQGHQPRLPHTGSQSGMPPVG SSGNRMLVAPQGPPSIPPQGSIRPMIPPNALRQSSTGPLTPQSNIRPPMG PQVPQPIIRPQQPGSPQIMGQQPIFPQGGVRHPTSQAGAPSPQHQGLVRP VTNDWQHIRQPGPGVDQRFPQPHQSQIRGGFPPRVGGPLPQQRPMVPQMR PLQPQTGPQNPRMNQPQNTYQQQRPMNPQHSNLTPQQRPPLTPNTLLNDF VPPSMSNNLPQPLMPEKNNQPQDIFTNNPQQHHSQMQRQSSRQDNLQQIQ PMNPQQFSQQNSQQFSQQNFLQNQQPSLQNQQHFQPQNQSQQMQSPNQLI RSQQQQPQQQQPQQQQPQQQQPQQQSRHAQPMPIPSQQQIRPTINQQPQE QKNIFPPPQSQQQFHNTPPMSPYMSTSQPQSMQQYQNSQPNSMQNFSNPQ LTSMDRIQISQPNSIQTISNPQLASLSNMQIPQQKSIQNLPTSRPIVPQN QQSFSGNNITPIQIPNSMATSMLDSPELVTPRANQNIPTAFQQPMMFQQQ QIRPIRSQSDQAQPIRNQGIQGIKPINNQPSQIQAIRSQPEQIKPIMSQH GQIQPINSQPSQIQPIRNQQIIPQSPSAPPIAPSVPDFPITPQPYPGPSG ISMVPPGSLLTGKPLMASSQHDTIISNILNKQTQQQPATNYQSEINTLSM QQMQLQQTMMLQQQQHQQMLAAMLQTQNQKVDKSEEEAKIHNLESQLASI KDLLKLQQESTKQDTEKHRMEQEILALKQQLAQKDTLKTSPSVATTLNTT LTTLMQPLQGTKETSTIGTSPRPPADVDRQSPDVILPRALESSVDNISTN SSLNTTNESTPNFSLATTVENDKIPFYEPKLDQKVKQPIKQESKDSENEY IVPRKLSQEIKSSPEMISPPTQPSLKREESSDTEYIVPRTPDSLSPKDEQ TKNLITDGINNIKRTLKRDSESSENDLIVPRTQEVQPPSKDVEIKPSTIT TQGPTSPIIIPATPTSETLPISPSSHDDVIRPRQPFADSNVDSKTKNDNS TSSTPTLDSVKRVIPKDLNENPNNRFSPINSPSMMKKFGDQHPIVRQSPR GGNSPITSVRSSPRGGNSPNTSAKSSLRSSPILCANGQGVQLDDLEGVID HRHLARQLGRLSFYVGEPDEKQWRKYIGELSIQVEKFNNHCKSLCKPQAN SYIDGFKIIWEDLAKQEQMDIKSFSAIAGEKNTSKNRYRDILPWDHSRVK LNTSSDDYINATHINELTPRSPSFIATQGPIPQTFEDFWRMVWEQNSSII VMLTKEIEGTKLKCHPYWTRSASSTTSSGSKAEFGHMLVEVFEEKECSAW KVRSIRLNNNKEKETRYIRHFQFTSWPDYGTPESPYELLSFMAEVYAGQQ MYDPAAQNPMILHCSAGVGRTGSFCCIYSAIREMEGQNGLIEIPGVIRKL RQSRQHMVQRMEQMIFCFQAVCCFAQQFIDTEKSKLVDRSRAASLQSSTS FDDAAFSSSPRGSKVGTNLVPMAMLDNQSELSISGTLNDSFDPKETSENS Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0006470 | protein dephosphorylation |
GO:0016311 | dephosphorylation |
Vocabulary: Molecular Function
Term | Definition |
GO:0004725 | protein tyrosine phosphatase activity |
GO:0005515 | protein binding |
GO:0016791 | phosphatase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0016311 |
dephosphorylation |
biological_process |
GO:0006470 |
protein dephosphorylation |
molecular_function |
GO:0016791 |
phosphatase activity |
molecular_function |
GO:0005515 |
protein binding |
molecular_function |
GO:0004725 |
protein tyrosine phosphatase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
None | No IPR available | COILS | Coil | Coil | coord: 405..425 |
None | No IPR available | COILS | Coil | Coil | coord: 1474..1537 |
None | No IPR available | COILS | Coil | Coil | coord: 641..661 |
None | No IPR available | GENE3D | 1.20.120.560 | | coord: 331..603 e-value: 6.4E-34 score: 117.1 |
None | No IPR available | GENE3D | 1.25.40.280 | | coord: 1..330 e-value: 6.8E-95 score: 317.5 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1076..1199 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 758..1046 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1634..1700 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1715..1880 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 716..742 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 659..699 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1557..1582 |
None | No IPR available | CDD | cd00047 | PTPc | coord: 1985..2221 e-value: 9.14786E-91 score: 296.034 |
IPR000242 | PTP type protein phosphatase | PRINTS | PR00700 | PRTYPHPHTASE | coord: 2007..2014 score: 66.03 coord: 2024..2044 score: 64.9 coord: 2116..2133 score: 49.58 coord: 2191..2206 score: 24.26 coord: 2159..2177 score: 61.64 coord: 2207..2217 score: 47.75 |
IPR000242 | PTP type protein phosphatase | SMART | SM00194 | PTPc_3 | coord: 1955..2226 e-value: 1.8E-94 score: 329.8 |
IPR000242 | PTP type protein phosphatase | PFAM | PF00102 | Y_phosphatase | coord: 1982..2221 e-value: 1.4E-70 score: 237.4 |
IPR000242 | PTP type protein phosphatase | PROSITE | PS50055 | TYR_PHOSPHATASE_PTP | coord: 1956..2224 score: 48.321 |
IPR004328 | BRO1 domain | SMART | SM01041 | BRO1_2 | coord: 1..354 e-value: 1.0E-104 score: 363.9 |
IPR004328 | BRO1 domain | PFAM | PF03097 | BRO1 | coord: 1..350 e-value: 3.3E-107 score: 358.6 |
IPR004328 | BRO1 domain | PROSITE | PS51180 | BRO1 | coord: 1..364 score: 52.395 |
IPR003595 | Protein-tyrosine phosphatase, catalytic | SMART | SM00404 | ptp_7 | coord: 2117..2223 e-value: 4.7E-26 score: 102.6 |
IPR025304 | ALIX V-shaped domain | PFAM | PF13949 | ALIX_LYPXL_bnd | coord: 384..664 e-value: 9.6E-29 score: 100.5 |
IPR029021 | Protein-tyrosine phosphatase-like | GENE3D | 3.90.190.10 | | coord: 1927..2232 e-value: 7.8E-93 score: 310.4 |
IPR029021 | Protein-tyrosine phosphatase-like | SUPERFAMILY | 52799 | (Phosphotyrosine protein) phosphatases II | coord: 1955..2228 |
IPR016130 | Protein-tyrosine phosphatase, active site | PROSITE | PS00383 | TYR_PHOSPHATASE_1 | coord: 2162..2172 |
IPR000387 | Tyrosine specific protein phosphatases domain | PROSITE | PS50056 | TYR_PHOSPHATASE_2 | coord: 2139..2215 score: 16.572 |
Blast
BLAST of TCONS_00057661-protein vs. Swiss-Prot (Human)
Match: PTN23 (Tyrosine-protein phosphatase non-receptor type 23 OS=Homo sapiens GN=PTPN23 PE=1 SV=1) HSP 1 Score: 468.389 bits (1204), Expect = 6.852e-136 Identity = 247/684 (36.11%), Postives = 408/684 (59.65%), Query Frame = 0
Query: 1 QYIQNFYHEDPNAYKNEIQTISNMRKGIGNIPYDIQGCKTLRKYFTQLYYLQSRFPMLDGGEAAVPFIWFDVYSGEPVMYKDIRYEQACVLFNIGALYSHLAVREQRQTDESLKTAVQHFQSAAGAFQYLKDNYLLSECIDMTEDVLSLKIKIMLGQAVECILEKSILENKNPTTIARIAAQIVDTFNECINLFSKSGTSEMDPDVKKMWMKSLKVKIKSYETISYVYMSNDADHKEKYGEKVTYLKAASDKIAEALKLSKSQ---TNETVNFIADVVQVKYEDAKKNNDFIYHMKIPDISEMDQIKGVDIVKPVPFLYNDKDVAGPDIFQRLVPMKAHEASSLYSDKKDTLLRSLVNEVEEKDVSLSQYLTAMKIE-ELLDPKE--NKLPDDLQDKNKFLQSNPDLIPKAEKLVEELAGLSSELDGLIKDSKVILD---------QEMRIDAQENSGREMGTLREYDKKLTQCRDTHGEAQTVNMKLVQTIIEKKSMIEFLSGDPKNILASLPSLHVVDDSIDDALVQRIREILGKVDKMRTQRQSLMQTLRTEFDKDDVTAQLVVLKDGGNRQAFFDEQIKKHDKNIAYLRQNLSAQDNIIQALTEANAKYAVTREKELGCKGEFDREVNRYMND-IKLFLAFQDRIRSS--GIPFFKELQKEVNALHQKIVEFSNDRKKKR 666
+++ Y E+P AY E++ + +R+ +P D +GC LRKY QL+YLQSR PM G EAAVP W +++SG+ V ++DI+YEQAC+L+N+GAL+S L ++R ++E +K + HFQ AAGAF YL++++ + +DM+ +L+L + +MLGQA EC+LEKS+L+N+ +ARI+AQ+VD + E T+ + ++K W K +++KI + +++++M A+ ++K+GE+V Y ++A DK+ EA+KL+K Q + + F DV+ KY AKK+NDFIYH +P + + +KG +VKP+P D V GPDIF +LVPM AHEASSLYS++K LLR ++ ++E+K+ L Q++ +M+++ E +D + + +P L +K L PD + + ++ L+G+ ++++ +KD + +L+ QE A S L E ++ + + H +A N +L + + + LSG + A+LP+ + + D A++Q ++ IL KV +MR QR SL Q LR KDD+TA LV D + F+EQ+KK+D+ YL QNL+AQD ++ ALTEAN +YA R + D++ N + + + A++D ++ S G F+ +L+ +V AL ++ R+ R
Sbjct: 28 KFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQAGAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPE--DKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVT-TDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRR----VLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAAR 704 HSP 2 Score: 206.838 bits (525), Expect = 3.329e-53 Identity = 97/277 (35.02%), Postives = 154/277 (55.60%), Query Frame = 0
Query: 1953 IDGFKIIWEDLAKQEQMDIKSFSAIAGEKNTSKNRYRDILPWDHSRVKLNTSSDDYINATHINELTPRSPSFIATQGPIPQTFEDFWRMVWEQNSSIIVMLTKEIEGTKLKCHPYWTRSASSTTSSGSKAEFGHMLVEVFEEKECSAWKVRSIRLNNNKEKETRYIRHFQFTSWPDYGTPESPYELLSFMAEVYAGQQMYDPAAQNPMILHCSAGVGRTGSFCCIYSAIREMEGQNGLIEIPGVIRKLRQSRQHMVQRMEQMIFCFQAVCCFAQQFI 2229
+ +W +L ++ D + S + KNR++D++P+D +RV L + DDYINA+ + L+P P +ATQ P+P T DFW MV EQ S+IVML E E K K Y+ T G G + + + + R + L + R + H F +WP+ G P+SP LL F+ EV+A ++ P+I+HCS+GVGRTG+F +Y+A++E+E NG+ E+P ++R++RQ R+HM+Q + FC++AV +Q +
Sbjct: 1188 VGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYF------PTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHA-HYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVL 1457
The following BLAST results are available for this feature:
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