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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00058541-protein ID=TCONS_00058541-protein|Name=TCONS_00058541-protein|organism=Clytia hemisphaerica|type=polypeptide|length=855bp ADSEKRFKKLQRSKTKKMAGAGPVSQKLPSIVVPQLLSEGGRFLKWDESD ANCTFHIVEVDPKGHVLSWKPEDYSKDTEVLELVHVRDVRTGQYARTPKX PVSNLFYYFIPLLWLEFELLCFRLVKHFATGKDDKKRAYDMMSNAGLAQG KRDFIKVKDFTFERFLTFYNSLVTRKDLDVIFTDLGAKRKPYLTADQLVD FLNSHQRDPRLNEILFPYYNSQRANGIIQRYELNKDFANKGFISIQGLTS FLMSEDNSILLPEKLQIHQEMTFPMAHYFINSSHNTYLTGHQLTGKSSVE IYRQVLLSGCRCIELDCWDGKGEDLEPVITHGMTLCTEVPFKDVLEAIAE SAFKTTDYPVVLSFENHCSAKQQKKMANYCLLIFGDMLLNKSIEDFPLEK DVELPSPKDLKNKILIKNKKRVIKETKSQASVELTGQQSVDSGNVSIPLD TTIPEEPTENDGNDGEPEVEVVQKSEEEEQEEVEAQQELSELVNYFQPVH FRGFDKAEKFRKCYEMSSFSENAAMNLLKESPVEFVNYNKFQPSRIYPKG QRISSDNYNPQMFWNAGCQFVALNFQTLDVPMMLNLGKFETNGRCGYLLK PEHMRRKDRTFDPFVDSMVDGVIAGTVHVKVISGQCLSERRCGAYVDVEM FGLPADIVRKQYRTKVVQNNTVNPVFDEEPFKFKVIMPHLAVLRICVYED NGKLIGHRILPIDGLSPGFRHIKLRNESYQPLCLPTLFVEIVTKDYVPES LNDFANALTNPQKYLSEKEQRAKKLEALMEEGDQEGGTEGGKVNGNNKPT GMINKDGAAEKKEKTSKIILSFFRHRLMFSRSQFSKYKIDFLSGNFSAKF EIDQG Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0035556 | intracellular signal transduction |
GO:0007165 | signal transduction |
GO:0006629 | lipid metabolic process |
Vocabulary: Molecular Function
Term | Definition |
GO:0004435 | phosphatidylinositol phospholipase C activity |
GO:0008081 | phosphoric diester hydrolase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0035556 |
intracellular signal transduction |
biological_process |
GO:0006629 |
lipid metabolic process |
biological_process |
GO:0007165 |
signal transduction |
molecular_function |
GO:0004435 |
phosphatidylinositol phospholipase C activity |
molecular_function |
GO:0008081 |
phosphoric diester hydrolase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
None | No IPR available | COILS | Coil | Coil | coord: 469..495 |
None | No IPR available | COILS | Coil | Coil | coord: 765..785 |
None | No IPR available | GENE3D | 1.10.238.10 | | coord: 169..265 e-value: 1.7E-17 score: 63.2 |
None | No IPR available | CDD | cd00275 | C2_PLC_like | coord: 626..741 e-value: 1.02071E-37 score: 137.288 |
None | No IPR available | CDD | cd08591 | PI-PLCc_beta | coord: 268..592 e-value: 1.51891E-165 score: 483.378 |
IPR001192 | Phosphoinositide phospholipase C family | PRINTS | PR00390 | PHPHLIPASEC | coord: 543..564 score: 56.09 coord: 710..720 score: 43.4 coord: 274..292 score: 70.31 coord: 300..320 score: 60.92 coord: 403..420 score: 60.69 coord: 564..582 score: 58.39 |
IPR000008 | C2 domain | SMART | SM00239 | C2_3c | coord: 626..724 e-value: 1.1E-13 score: 61.4 |
IPR000008 | C2 domain | PFAM | PF00168 | C2 | coord: 625..714 e-value: 3.6E-7 score: 30.3 |
IPR000008 | C2 domain | GENE3D | 2.60.40.150 | | coord: 617..745 e-value: 4.9E-15 score: 55.1 |
IPR000008 | C2 domain | PROSITE | PS50004 | C2 | coord: 612..709 score: 19.618 |
IPR000008 | C2 domain | SUPERFAMILY | 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | coord: 625..742 |
IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | SMART | SM00149 | plcy_3 | coord: 489..605 e-value: 5.5E-63 score: 225.2 |
IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | PFAM | PF00387 | PI-PLC-Y | coord: 489..602 e-value: 2.6E-42 score: 143.7 |
IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | PROSITE | PS50008 | PIPLC_Y_DOMAIN | coord: 489..605 score: 52.413 |
IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | SMART | SM00148 | plcx_3 | coord: 269..419 e-value: 7.5E-77 score: 271.3 |
IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | PFAM | PF00388 | PI-PLC-X | coord: 271..420 e-value: 9.9E-63 score: 210.0 |
IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | PROSITE | PS50007 | PIPLC_X_DOMAIN | coord: 269..419 score: 60.129 |
IPR015359 | Phosphoinositide-specific phospholipase C, EF-hand-like domain | PFAM | PF09279 | EF-hand_like | coord: 168..260 e-value: 2.0E-10 score: 40.9 |
IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain | GENE3D | 3.20.20.190 | | coord: 266..616 e-value: 1.6E-140 score: 467.4 |
IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain | SUPERFAMILY | 51695 | PLC-like phosphodiesterases | coord: 269..606 |
IPR011993 | PH domain-like | SUPERFAMILY | 50729 | PH domain-like | coord: 33..102 |
IPR011992 | EF-hand domain pair | SUPERFAMILY | 47473 | EF-hand | coord: 134..268 |
Blast
BLAST of TCONS_00058541-protein vs. Swiss-Prot (Human)
Match: PLCB4 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens GN=PLCB4 PE=1 SV=3) HSP 1 Score: 706.827 bits (1823), Expect = 0.000e+0 Identity = 351/688 (51.02%), Postives = 465/688 (67.59%), Query Frame = 0
Query: 124 LVKHFATGKDDKKRAYDMMSNAGLAQGKRDFIKVKDFTFERFLTFYNSLVTRKDLDVIFTDLGAKRKPYLTADQLVDFLNSHQRDPRLNEILFPYYNSQRANGIIQRYELNKDFANKGFISIQGLTSFLMSEDNSILLPEKLQIHQEMTFPMAHYFINSSHNTYLTGHQLTGKSSVEIYRQVLLSGCRCIELDCWDGKGEDLEPVITHGMTLCTEVPFKDVLEAIAESAFKTTDYPVVLSFENHCSAKQQKKMANYCLLIFGDMLLNKSIEDFPLEKDVELPSPKDLKNKILIKNKKRVIKETKSQASVELTGQQSVDSGNVSIPLDTTIPEEPTENDGND-GEPEV--------------EVVQKSEEEEQEEVEAQQE-----------------LSELVNYFQPVHFRGFDKAEKFRKCYEMSSFSENAAMNLLKESPVEFVNYNKFQPSRIYPKGQRISSDNYNPQMFWNAGCQFVALNFQTLDVPMMLNLGKFETNGRCGYLLKPEHMRRKDRTFDPFVDSMVDGVIAGTVHVKVISGQCLSERRCGAYVDVEMFGLPADIVRKQYRTKVVQNNTVNPVFDEEPFKF-KVIMPHLAVLRICVYEDNGKLIGHRILPIDGLSPGFRHIKLRNESYQPLCLPTLFVEIVTKDYVPESLNDFANALTNPQKYLSEKEQRAKKLEAL 778
+ + FA+GK +K + + GL GK D I+ F++E+F + R D++ +F + + YLT DQLV FLN HQRDPRLNEILFP+Y+++RA II+ YE ++D KG IS G +LMS++N+ + ++L+++QEM P+AHYFI+SSHNTYLTG Q GKSSVE+YRQVLL+GCRC+ELDCWDGKGED EP+ITHG +CT++ FKDV++AI E+AF T++YPV+LSFENHCS QQ KM+ YC +FGD+LL +++E PLE LPSP DLK KILIKNK+ + K Q + ++ +S + + L+ EE D + PE E V S ++ VE +Q LS ++NY QPV F+GF AE+ Y MSSF+E+ + LK +EFVNYNK Q SRIYPKG R+ S NY PQ+FWNAGCQ V+LN+QT D+ M LN GKFE NG CGYLLKP+ MRR DRTFDPF ++ VDGVIA T V+VISGQ LS+++ G YV+V+M+GLP D +RK++RT++V NN +NPV++EE F F KVI+P LAVLRI VY+DN KLIG RILP+DGL G+RHI LRNE +PL LPT+F IV K YVP+ D +AL++P+K+LS E+RA ++ A+
Sbjct: 169 ITRTFASGKTEK-VIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAM 855
The following BLAST results are available for this feature:
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