TCONS_00058558-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00058558-protein
Unique NameTCONS_00058558-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length321

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00058558-protein ID=TCONS_00058558-protein|Name=TCONS_00058558-protein|organism=Clytia hemisphaerica|type=polypeptide|length=321bp
MAQIIDGKDIARRIRDQIKIDVSQLNSETGLTPGLAIVQVGNREDSNVYV
RTKLKFAQQLGMNAEILKLPNTSTEQELLSTVERLNNDDNVHGIIVQLPL
DSENPIDSALATNAVSPEKDVDGINDINAGRLARGSLDTCFAPCTPNGCM
ELIKTTGMEVSGQNAVVLGRSKIVGTPMEELLKWHNATVTTCHSRTRNLP
EVVGRADIVVAAVGVPEMVKGNWIKPGAVVIDCGITAVPDSSKKSGQRLV
GDCDYKACKERASWITPVPGGVGPMTVAMLLYNTVESCKRVAKERQFLKS
GFGISLKNARMLRSMLRRFRF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036885XLOC_036885Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00058558TCONS_00058558Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000672THF_DH/CycHdrlase
IPR020630THF_DH/CycHdrlase_cat_dom
IPR020631THF_DH/CycHdrlase_NAD-bd_dom
IPR020867THF_DH/CycHdrlase_CS
IPR016040NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Molecular Function
TermDefinition
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0003824catalytic activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000672Tetrahydrofolate dehydrogenase/cyclohydrolasePRINTSPR00085THFDHDRGNASEcoord: 265..283
score: 84.41
coord: 111..132
score: 51.22
coord: 33..55
score: 53.34
coord: 207..236
score: 55.9
coord: 248..264
score: 39.37
coord: 158..178
score: 53.66
coord: 74..101
score: 51.24
IPR000672Tetrahydrofolate dehydrogenase/cyclohydrolaseHAMAPMF_01576THF_DHG_CYHcoord: 2..292
score: 36.012
IPR020630Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domainPFAMPF00763THF_DHG_CYHcoord: 4..122
e-value: 2.8E-37
score: 127.4
NoneNo IPR availableGENE3D3.40.50.720coord: 139..273
e-value: 4.3E-40
score: 136.4
NoneNo IPR availableGENE3D3.40.50.10860coord: 10..138
e-value: 1.1E-40
score: 137.9
NoneNo IPR availableCDDcd01080NAD_bind_m-THF_DH_Cyclohydcoord: 117..289
e-value: 8.02067E-93
score: 275.203
NoneNo IPR availableSUPERFAMILY53223Aminoacid dehydrogenase-like, N-terminal domaincoord: 1..123
IPR020631Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domainPFAMPF02882THF_DHG_CYH_Ccoord: 126..290
e-value: 8.4E-68
score: 226.6
IPR020867Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved sitePROSITEPS00766THF_DHG_CYH_1coord: 75..100
IPR020867Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved sitePROSITEPS00767THF_DHG_CYH_2coord: 269..277
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 125..289

Blast
[Close]
BLAST of TCONS_00058558-protein vs. Swiss-Prot (Human)
Match: C1TC (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3)

HSP 1 Score: 374.4 bits (960), Expect = 5.553e-123
Identity = 176/290 (60.69%), Postives = 227/290 (78.28%), Query Frame = 0 
Query:    2 AQIIDGKDIARRIRDQIKIDVSQLNSET-GLTPGLAIVQVGNREDSNVYVRTKLKFAQQLGMNAEILKLPNTSTEQELLSTVERLNNDDNVHGIIVQLPLDSENPIDSALATNAVSPEKDVDGINDINAGRLARGSLDTCFAPCTPNGCMELIKTTGMEVSGQNAVVLGRSKIVGTPMEELLKWHNATVTTCHSRTRNLPEVVGRADIVVAAVGVPEMVKGNWIKPGAVVIDCGITAVPDSSKKSGQRLVGDCDYKACKERASWITPVPGGVGPMTVAMLLYNTVESCKR 290
            A+I++GK+I+ +IR ++K  V+QL  +  G TP LAI+QVGNR+DSN+Y+  KLK A+++G+ A  +KLP T+TE E++  +  LN D  VHG +VQLPLDSEN I++    NA++PEKDVDG+  INAGRLARG L+ CF PCTP GC+ELIK TG+ ++G++AVV+GRSKIVG PM +LL W+NATVTTCHS+T +L E V + DI+V A G PEMVKG WIKPGA+VIDCGI  VPD  K +G+++VGD  Y   KERAS+ITPVPGGVGPMTVAML+ +TVES KR
Sbjct:    4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKR 293
The following BLAST results are available for this feature:
BLAST of TCONS_00058558-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
C1TC5.553e-12360.69C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo... [more]
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