TCONS_00059509-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00059509-protein
Unique Name	TCONS_00059509-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	461

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00059509-protein ID=TCONS_00059509-protein|Name=TCONS_00059509-protein|organism=Clytia hemisphaerica|type=polypeptide|length=461bp
MYPATHQCAPGAWEKEKVKTLLKKFEFPRESAEELISKMNEDFSYGLKNG
GDYHSPVKMLLTYVHGLPDGTETGDYFALDLGGTNFRVLLVKLHDGNVSM
SHETFPISQETMKGDADGLFGYIAECLAKFAKLKLGQETRKLGTVGFTFS
FPVRQESLTCGSLIKWTKGFDVDDVEDHDVVALLQQAIEKRNEIEVEQIA
LLNDTTGVMMSCAYNDPDVMVGMILGTGSNACYMEKLEYVGKWFHPQSPY
KECIINTEWGAYGDMDELQSVSTSYDKIVDEESLYPGKQLFEKMISGMYL
GEIVRQCILSLIKDFVLFRGYISPQLGKKDSFTTIYVSEFCSGDAMKCVN
ILHQLGYEAATIEDCHVMQDICIAVSLRAARLAAAGLTCILRRLKRSSVS
VAMDGSLYKKHPTFKRFMHQALEEFLPTTQVNLRLAEDGSGRGAAVVAAV
AQRLAKAALVD

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_037461	XLOC_037461	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00059509	TCONS_00059509	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR022672	Hexokinase_N
IPR022673	Hexokinase_C
IPR019807	Hexokinase_BS
IPR001312	Hexokinase

Vocabulary: **Biological Process**
Term	Definition
GO:0005975	carbohydrate metabolic process
GO:0006096	glycolytic process
GO:0001678	cellular glucose homeostasis
GO:0046835	carbohydrate phosphorylation

Vocabulary: **Molecular Function**
Term	Definition
GO:0005524	ATP binding
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0004396	hexokinase activity
GO:0005536	glucose binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0005975	carbohydrate metabolic process
biological_process	GO:0046835	carbohydrate phosphorylation
biological_process	GO:0001678	cellular glucose homeostasis
biological_process	GO:0006096	glycolytic process
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0005536	glucose binding
molecular_function	GO:0004396	hexokinase activity
molecular_function	GO:0016773	phosphotransferase activity, alcohol group as acceptor

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00475	HEXOKINASE	coord: 145..170 score: 62.79 coord: 198..214 score: 48.84 coord: 77..93 score: 75.24 coord: 434..450 score: 62.38 coord: 289..311 score: 61.27 coord: 221..235 score: 70.85 coord: 368..390 score: 38.22
None	No IPR available	GENE3D	3.40.367.20		coord: 216..460 e-value: 8.4E-90 score: 300.0
None	No IPR available	GENE3D	3.30.420.40		coord: 62..215 e-value: 1.2E-60 score: 203.6
None	No IPR available	CDD	cd00012	NBD_sugar-kinase_HSP70_actin	coord: 78..236 e-value: 1.4045E-9 score: 54.9023
None	No IPR available	SUPERFAMILY	53067	Actin-like ATPase domain	coord: 16..216
None	No IPR available	SUPERFAMILY	53067	Actin-like ATPase domain	coord: 218..454
IPR022672	Hexokinase, N-terminal	PFAM	PF00349	Hexokinase_1	coord: 18..214 e-value: 9.3E-62 score: 208.4
IPR022673	Hexokinase, C-terminal	PFAM	PF03727	Hexokinase_2	coord: 221..450 e-value: 1.9E-76 score: 256.6
IPR019807	Hexokinase, binding site	PROSITE	PS00378	HEXOKINASE_1	coord: 145..170
IPR001312	Hexokinase	PROSITE	PS51748	HEXOKINASE_2	coord: 12..449 score: 45.481

Blast

[Close]

BLAST of TCONS_00059509-protein vs. Swiss-Prot (Human)
Match: HKDC1 (Putative hexokinase HKDC1 OS=Homo sapiens GN=HKDC1 PE=1 SV=3)

HSP 1 Score: 376.711 bits (966), Expect = 7.338e-122
Identity = 205/454 (45.15%), Postives = 288/454 (63.44%), Query Frame = 0

Query:   14 EKEKVKTLLKKFEFPRESAEELISKMNEDFSYGLKNGGDYHSPVKMLLTYVHGLPDGTETGDYFALDLGGTNFRVLLVKLHDG--NVSMSHETFPISQETMKGDADGLFGYIAECLAKFAKLKLGQETRKLGTVGFTFSFPVRQESLTCGSLIKWTKGFDVDDVEDHDVVALLQQAIEKRNEIEVEQIALLNDTTGVMMSCAYNDPDVMVGMILGTGSNACYMEKLEYVGKWFHPQSPYKECIINTEWGAYGDMDELQSVSTSYDKIVDEESLYPGKQLFEKMISGMYLGEIVRQCILSLIKDFVLFRGYISPQLGKKDSFTTIYVSEFCSGD--AMKCVNILHQLGYEAATIEDCHVMQDICIAVSLRAARLAAAGLTCILRR------LKRSSVSVAMDGSLYKKHPTFKRFMHQALEEFLPTTQVNLRLAEDGSGRGAAVVAAVAQRLAKA 457
            +++++  +L  F+  RE   ++ +KM  +  YGLK      + V+ML TYV GLPDGTE G + ALDLGGTNFRVLLVK+  G  +V M ++ F I  E M+G  + LF +I +C+A F    +G +   L  +GFTFSFP RQ S+  G+LI WTKGF   D E  DVV +L++AI++RNE +++ +A++NDT G MM+C Y DP+  +G+I GTGSN CYME +  +          K C INTEWG +GD   +  + T YD  VDE SL PGKQ +EKM SGMYLGEIVRQ ++ L K  +LFRG IS +L  +  F T ++S+  S     ++   IL QLG + +T ED  V++++C AVS RAA+L  AGL  I+ +      L+   ++V +DG+LYK HP F R + + ++E  P   V   L+EDGSG+GAA++ AVA+RL +A
Sbjct:  466 QRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDY-MGLKGASL-PLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNI--EMVEGGEGKMC-INTEWGGFGDNGCIDDIWTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLD-STCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQQA 913

HSP 2 Score: 303.908 bits (777), Expect = 3.559e-94
Identity = 180/451 (39.91%), Postives = 268/451 (59.42%), Query Frame = 0

Query:   16 EKVKTLLKKFEFPRESAEELISKMNEDFSYGLKNGGDYHSPVKMLLTYVHGLPDGTETGDYFALDLGGTNFRVLLVKLHD---GNVSMSHETFPISQETMKGDADGLFGYIAECLAKFAKLKLGQETRKLGTVGFTFSFPVRQESLTCGSLIKWTKGFDVDDVEDHDVVALLQQAIEKRNEIEVEQIALLNDTTGVMMSCAYNDPDVMVGMILGTGSNACYMEKLEYVGKWFHPQSPYKECIINTEWGAYGDMDELQSVSTSYDKIVDEESLYPGKQLFEKMISGMYLGEIVRQCILSLIKDFVLFRGYISPQLGKKDSFTTIYVS---EFCSGDAMKCVNILHQLGYEAATIEDCHVMQDICIAVSLRAARLAAAGLTCIL------RRLKRSSVSVAMDGSLYKKHPTFKRFMHQALEEFLPTTQVNLRLAEDGSGRGAAVVAAVAQRL 454
            +KV   L       ++  +++ +   +   GL    +  + VKML T+V  +PDG+E G++ +LDLGG+ FRVL V++ +    +V M  + +P   E ++G+   LF Y+A+CLA F K K   + +KL  +G TFSFP RQ  L  G L+ WTK F    V+D DVV+ L +A+ +  +++V+ +AL+NDT G MM+CAY+DP   VG+I+GTG+NACYME +  +      +       INTEWGA+GD   L+ + T +D+ +D  SL PGKQLFEKMISG+YLGE+VR  +L + K  +LF G  S  L  K    T +V+   ++  G A     IL  LG E +   DC  +Q +C  VS R+A L AA L  IL      ++++R   +V MDG+LYK HP + + +H+ + + +P+  V   L+E GS +GAA+V AVA R+
Sbjct:   20 KKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK-DLKHKKL-PLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNID---LVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLA-NTREILVDLGLEPSE-ADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRV 463

The following BLAST results are available for this feature:

BLAST of TCONS_00059509-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00059509-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
HKDC1	7.338e-122	45.15	Putative hexokinase HKDC1 OS=Homo sapiens GN=HKDC1...	[more]

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TCONS_00059509-protein (polypeptide) - C. hemisphaerica