TCONS_00059791-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00059791-protein
Unique NameTCONS_00059791-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length699

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00059791-protein ID=TCONS_00059791-protein|Name=TCONS_00059791-protein|organism=Clytia hemisphaerica|type=polypeptide|length=699bp
MAKILAECLENVVFLQATFQFTGSNEDELSFNKDDVFVITKKDDGGWWEG
TLDGKIGWFPNNYVKEISSEPEPTPSEIPSLSSTEEASAYYTQVVENIIE
AQKKHLNELKNFLDTYLLKVKNSEVLKQQDRDVIASNYSDIVDFHVNLTK
ELVEQQEKPIPEQRFGECFLKKSKEMKEIYLTYCNNHPQAAALIQQHGDE
LGEFMESLGAANPGIMTLTSLLSKPFLYVEKYGNQIKELERHVEEDHIDK
LDMKKATQVLQIIALSCNEVRKKKEMELQMLTGDIEGWQGDPISSLGNLV
HMGQVFLEKEDVARRERYFCLFPNDLIVLSVSAELVGYCFEERQLVSDIS
AKDVEDTDTFFNGFQVIVSDNVWQVMSSSPREKDAWMDALKKVLNDKFIP
LPAPIVVPEVKRTGANLERSDSKRSEVKSAPVLDHNAENAAFLRSYSTGA
TLNDKQRHTAISASPTPESQRREALSSVRGSVRQPVKKEWSFTRLRPTPP
YQQNSNLKTSDTTGSPRAMRRIVSAKNKMIGGKGSREDLLADNFGRKGST
PTTGSLGLTSRQILEEDMMILSVIEAYCFSARSRQNMNPGSPDSPFLPPD
VPPHFSFKPITPPRQTQSTGKQKSLKKSKKKPMDTNAELDGLKHQVQNLH
KQTLYLRENLEEERKARENFERFFKKIVQHISPDVDLNADNLPSKSTPI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037616XLOC_037616Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00059791TCONS_00059791Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR001849PH_domain
IPR000219DH-domain
IPR011993PH_dom-like
IPR011511SH3_2
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0005089Rho guanyl-nucleotide exchange factor activity
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005515 protein binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001452SH3 domainPRINTSPR00452SH3DOMAINcoord: 27..42
score: 33.61
coord: 44..53
score: 38.09
coord: 55..67
score: 42.8
IPR001452SH3 domainSMARTSM00326SH3_2coord: 13..68
e-value: 3.8E-22
score: 89.6
IPR001452SH3 domainPROSITEPS50002SH3coord: 10..69
score: 16.299
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 12..82
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 299..397
e-value: 1.4E-6
score: 37.9
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 298..395
score: 8.693
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 94..269
e-value: 8.8E-28
score: 108.3
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 94..268
e-value: 3.1E-23
score: 82.8
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 90..270
score: 22.951
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 81..281
NoneNo IPR availablePFAMPF16614RhoGEF67_u2coord: 480..587
e-value: 3.8E-6
score: 26.9
NoneNo IPR availableGENE3D2.30.30.40coord: 7..78
e-value: 1.3E-20
score: 72.4
NoneNo IPR availableGENE3D1.20.900.10coord: 79..277
e-value: 3.2E-35
score: 120.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 458..515
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 585..641
NoneNo IPR availableCDDcd00160RhoGEFcoord: 91..268
e-value: 5.82349E-28
score: 110.465
NoneNo IPR availableCDDcd11877SH3_PIXcoord: 16..66
e-value: 9.04251E-26
score: 100.081
IPR011993PH domain-likeGENE3D2.30.29.30coord: 278..397
e-value: 5.5E-14
score: 51.2
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 272..394
IPR011511Variant SH3 domainPFAMPF07653SH3_2coord: 16..67
e-value: 4.0E-16
score: 58.3

Blast
[Close]
BLAST of TCONS_00059791-protein vs. Swiss-Prot (Human)
Match: ARHG7 (Rho guanine nucleotide exchange factor 7 OS=Homo sapiens GN=ARHGEF7 PE=1 SV=2)

HSP 1 Score: 343.199 bits (879), Expect = 6.272e-107
Identity = 207/599 (34.56%), Postives = 323/599 (53.92%), Query Frame = 0 
Query:   11 NVVFLQATFQFTGSNEDELSFNKDDVFVITKKDDGGWWEGTLDGKIGWFPNNYVKEISSEPEPTPSEIPSLSS-------TEEASAYYTQVVENIIEAQKKHLNELKNFLDTYLLKVKNSEVLKQQDRDVIASNYSDIVDFHVNLTKELVEQQEKPIPEQRFGECFLKKSKEMKEIYLTYCNNHPQAAALIQQHGDELGEFMESLGAANPGIMTLTSLLSKPFLYVEKYGNQIKELERHVEEDHIDKLDMKKATQVLQIIALSCNEVRKKKEMELQMLTGDIEGWQGDPISSLGNLVHMGQVFLEKEDVARR-ERYFCLFPNDLIVLSVSAELVGYCFEERQLVSDISAKDVEDTDTFFNGFQVIVSDNVWQVMSSSPREKDA--WMDALKKVLNDKFI--PLPAPIVVPEVKRTGANLERSDSKRSEVKSAPV------LDHNAENAAFLRSYSTGATLNDKQRHTAISASPTPESQRREALSSVRGSVRQPVK--KEWSFTRLRPTPPYQQNSNL-KTSDTTGSPRAMRRIVSAKNKMIGGKGSREDLLADNFGRKGSTPTTGSLGLTSRQILEEDMMILSVIEAYCFSARSRQNMN 588
            N + ++A F F  +NEDELSF+K DV  +T+ ++GGWWEGTL+G+ GWFP+NYV+E+ +  +P   +  +L S       T    +YY  V++NI+E + ++  EL+  L TYL  ++ SE L   +   +  N  +I  F   L + L E  + P  +QR G CFL    +MK +YLTYC NHP A  ++ +H +ELGEFME+ GA++PGI+ LT+ LSKPF+ ++KY   +KELERH+E+ H D+ D++K+    + ++  C EVRK+KE+ELQ+LT  I  W+GD I +LGN+ +M QV ++      + ERY  LFPN L++LS S  + G+ ++ +   + ++   +ED++   N F+ I    + +++ S   ++D   W++ L+K      +  P   P  VP        +  S SK ++ K AP+      L H + +                  HT I+  P                  +P K  K WS + LRP PP + ++ L    D + SP+ M++++  +      K S E+     F  + ST             LEED  IL VIEAYC SA++RQ +N
Sbjct:  185 NQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFE-ISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPS-SKHADSKPAPLTPAYHTLPHPSHHGT---------------PHTTINWGPL-----------------EPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLLPKRKP--ERKPSDEE-----FASRKSTAA-----------LEEDAQILKVIEAYCTSAKTRQTLN 731
The following BLAST results are available for this feature:
BLAST of TCONS_00059791-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ARHG76.272e-10734.56Rho guanine nucleotide exchange factor 7 OS=Homo s... [more]
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