TCONS_00063140-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063140-protein
Unique NameTCONS_00063140-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length506

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063140-protein ID=TCONS_00063140-protein|Name=TCONS_00063140-protein|organism=Clytia hemisphaerica|type=polypeptide|length=506bp
QESLIRLTSLLKKMMKFELLVLLPIVALVNGSETEDRLLKKLFENYNAAA
RPVRFDKDAVNVVFGLSMSQIVDVHEKSQTLIISAWIRQLWHNQILKWNP
DEYNGIREINVDPKTIWRPDIVLYNNADEDKAFGGNLDRMNTRAIISYNG
FVKWLAPIILKSQCDIDVRYFPFDTQYCPLKFGSWTYNLARLNFFNESSG
ADLNKYSENSEWSLVSADCIRNEIKYTCCKEKYPDVTFTIVIARRSLFYL
CNLIFPMTVIGMLTILSFLLPAESGERVSLAITLLLAMTVFMLVVAEIIP
ATSDVVPLVGVFFTASMIEMVIMIVVLCYIMRLYHKGPNDPPMPLWMKKY
ILNWLSFLVGIRAREKNINKSRSSNLNNTFNSSHRNAFNNNATPNEQMTL
LNKYNRNSNEYNKENWKKKALCNLNASKCGDVGYMAPSGRLTEAQLVVSK
LDVFIERLRTMDEEDEVKNEWRTVAMTIDRCLLVIFFLVYIVTLLACFLR
SPGYVS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_039557XLOC_039557Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063140TCONS_00063140Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002394Nicotinic_acetylcholine_rcpt
IPR006201Neur_channel
IPR006029Neurotrans-gated_channel_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Molecular Function
TermDefinition
GO:0022848acetylcholine-gated cation-selective channel activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Cellular Component
TermDefinition
GO:0045211postsynaptic membrane
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0045211 postsynaptic membrane
molecular_function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002394Nicotinic acetylcholine receptorPRINTSPR00254NICOTINICRcoord: 69..85
score: 31.57
coord: 103..117
score: 30.15
coord: 121..133
score: 54.7
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 82..98
score: 26.78
coord: 164..178
score: 52.58
coord: 240..252
score: 31.12
coord: 115..126
score: 53.28
IPR006201Neurotransmitter-gated ion-channelTIGRFAMTIGR00860TIGR00860coord: 30..493
e-value: 2.4E-92
score: 308.0
NoneNo IPR availableGENE3D1.20.58.390coord: 252..504
e-value: 5.4E-41
score: 139.3
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 253..493
e-value: 1.8E-43
score: 149.2
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 247..501
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 35..245
e-value: 5.3E-63
score: 212.2
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 25..251
e-value: 9.6E-73
score: 243.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 34..245
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 164..178

Blast
[Close]
BLAST of TCONS_00063140-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 322.783 bits (826), Expect = 5.990e-105
Identity = 176/482 (36.51%), Postives = 271/482 (56.22%), Query Frame = 0 
Query:   28 LVNGSETEDRLLKKLFENYNAAARPVRFDKDAVNVVFGLSMSQIVDVHEKSQTLIISAWIRQLWHNQILKWNPDEYNGIREINVDPKTIWRPDIVLYNNADEDKAFGGNLDRMNTRAIISYNGFVKWLAPIILKSQCDIDVRYFPFDTQYCPLKFGSWTYNLARLNFFNESSGADLNKYSENSEWSLVSADCIRNEIKYTCCKEKYPDVTFTIVIARRSLFYLCNLIFPMTVIGMLTILSFLLPAESGERVSLAITLLLAMTVFMLVVAEIIPATSDVVPLVGVFFTASMIEMVIMIVVLCYIMRLYHKGPNDPPMPLWMKKYILNWLS---FLVGIRAREKNINKSRS------SNLNNTFNSSHRNAFNNNATPNEQMTLLNKYNRNSNEYNKENWKKKALCNLNASKCGDVGYMAPSGRLTEAQLVVSKLDVFIERLRTMDEEDEVKNEWRTVAMTIDRCLLVIFFLVYIVTLLACFLR 500
            +   SE E RL ++LFE+YN   RPV    D V + F +SMSQ+V V E +Q +  + W++Q+W++  LKWNP +Y G   + V  + IW+PDIVLYNNA  D           T+A++ Y G V W+ P I KS C IDV YFPFD Q C +KFGSW+Y+ A+++     S  +L  Y E+ EW+++ A   +++IKY CC+E YPD+T+++ I R  LFY  NLI P  +I  LT+L F LP++ GE+V+L I++LL++TVF+LV+ E IP+TS V+PL+G +   +MI + + IV+  +++ ++++ P    MP W+K   LN L    F+    + E N  K R       SNLN  F+ +            + M     + R        N     L   ++S+  D   ++ S    E +  +  +    E ++  +E  E++++W+ VAM IDR  L +F LV I+     FL+
Sbjct:   28 VARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDK-----TKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLN-CFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSAN-----LTRSSSSESVD-AVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQ 497
The following BLAST results are available for this feature:
BLAST of TCONS_00063140-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA35.990e-10536.51Neuronal acetylcholine receptor subunit alpha-3 OS... [more]
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