TCONS_00063884-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063884-protein
Unique NameTCONS_00063884-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length905

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063884-protein ID=TCONS_00063884-protein|Name=TCONS_00063884-protein|organism=Clytia hemisphaerica|type=polypeptide|length=905bp
ESMVSIWRQLKCGGGGRNMNTSEEDLNSKFFGKDSDSTSSDETLAPEQVE
AWLDKHEDFVASYYARKASKFLLDAFLRTKTSNRPASRTGSPLPFGSSGS
AIDIGRNASPLAYGGNAPASGCSTPRKSSVDTTSGLLKPLISHIDGIPSF
IRFERSLSRPRHRKSKEELKELRLVDEQALLMELATDIANDLEITSLCHK
ILQNVSILTDGDRCSLFMAQDYGPNGQKVLVSKVYDVNADSSVEEVTDKE
TIMVPWGCGIVGWVAENGKTLNIPDAYSDDRFNKDIDKKTGYYTKSILCM
PIKANVDEDGNSEVIAVAQVMNKQGATLNHAFTREDEKIFERYLVFCGIG
ICNAHLFDQLQQELKRNRVLLDLARAIFEEQSTLHDVVHKIMMNTQSLLQ
CERCSVLLVDPSAKGLFSKAFDLEARYYIDENGSVERKQSCGSSEVRFPI
NIGITGTVATTGETLNIPDAYEDPRFDPSVDGGSGFKTRTILCMPIKNSK
GDIIGVVQLLNKMDGKPFNPNDENLFEAFAIFCGMAIHNTYIYEECVKAN
ARQKIALDVLSYHATASDNESVHLVREIVPSSRTFHLREFSFDDAVLSDR
ETCLATIRMFQDLRLIQRFRIDYNVLCNWVLTVKKNYRNVIYHNWRHAFN
VAQSMFLFLKELQEFKVHFTDEEKLALLVGCLCHDLDHRGTNNTFQVKSA
SPLAQLYGTSVMEHHHFDHCIMILHSSGNEIFNTLSPEEYNLTINVLEHA
ILSTDLALYFTKRNDYKAMVTNQSFEWEDNSKRSLLRSMLMTACDISAIC
KPWKVQQRVAHLVAEEFFQQGDLELKKLNMTPIEMMDRAKKDKLPQMQVG
FIDGVCLPIYETLSTHYPYFKPLLDECLNNRKHWKTLADDNIKRQGNKKI
EEIVD
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_040048XLOC_040048Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063884TCONS_00063884Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR023088PDEase
IPR003607HD/PDEase_dom
IPR003018GAF
IPR029016GAF_dom-like
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: Molecular Function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:0005515protein binding
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007165 signal transduction
molecular_function GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function GO:0008081 phosphoric diester hydrolase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 638..651
score: 59.0
coord: 710..726
score: 39.65
coord: 684..699
score: 57.75
coord: 791..804
score: 53.57
coord: 808..824
score: 58.47
coord: 670..683
score: 39.71
IPR003607HD/PDEase domainSMARTSM00471hd_13coord: 640..809
e-value: 1.2E-9
score: 48.0
IPR003018GAF domainSMARTSM00065gaf_1coord: 193..361
e-value: 2.2E-20
score: 83.7
coord: 383..547
e-value: 5.6E-30
score: 115.6
IPR003018GAF domainPFAMPF01590GAFcoord: 194..348
e-value: 9.1E-15
score: 55.4
coord: 384..537
e-value: 8.2E-20
score: 71.7
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 369..553
e-value: 1.4E-37
score: 128.6
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 159..368
e-value: 8.1E-38
score: 129.5
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 176..379
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 364..564
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainGENE3D1.10.1300.10coord: 554..900
e-value: 4.1E-112
score: 374.0
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 642..877
e-value: 4.2E-77
score: 259.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 14..42
NoneNo IPR availableCDDcd00077HDccoord: 642..818
e-value: 1.93425E-12
score: 64.6681
NoneNo IPR availableSUPERFAMILY109604HD-domain/PDEase-likecoord: 581..891
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_Icoord: 684..695

Blast
[Close]
BLAST of TCONS_00063884-protein vs. Swiss-Prot (Human)
Match: PDE11 (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Homo sapiens GN=PDE11A PE=1 SV=2)

HSP 1 Score: 692.575 bits (1786), Expect = 0.000e+0
Identity = 358/776 (46.13%), Postives = 506/776 (65.21%), Query Frame = 0 
Query:  123 STPRKSSVDTTSGLLKPLISHIDGIPSFIRFERSLSRPRHRKSKEELK-ELRLVDEQALLMELATDIANDLEITSLCHKILQNVSILTDGDRCSLFMAQDYGPNGQKVLVSKVYDVNADSSVEEVTDKET---IMVPWGCGIVGWVAENGKTLNIPDAYSDDRFNKDIDKKTGYYTKSILCMPIKANVDEDGNSEVIAVAQVMNK--QGATLNHAFTREDEKIFERYLVFCGIGICNAHLFDQLQQELKRNRVLLDLARAIFEEQSTLHDVVHKIMMNTQSLLQCERCSVLLVD----PSAKGLFSKAFDLEARYYIDENGSVERKQSCGSSEVRFPINIGITGTVATTGETLNIPDAYEDPRFDPSVDGGSGFKTRTILCMPIKNSKGDIIGVVQLLNKMDGKPFNPNDENLFEAFAIFCGMAIHNTYIYEECVKANARQKIALDVLSYHATASDNESVHLVREIVPSSRTFHLREFSFDDAVLSDRETCLATIRMFQDLRLIQRFRIDYNVLCNWVLTVKKNYRNVIYHNWRHAFNVAQSMFLFLKELQEFKVHFTDEEKLALLVGCLCHDLDHRGTNNTFQVKSASPLAQLYGTSV-MEHHHFDHCIMILHSSGNEIFNTLSPEEYNLTINVLEHAILSTDLALYFTKRNDYKAMVTNQSFEWEDNSKRSLLRSMLMTACDISAICKPWKVQQRVAHLVAEEFFQQGDLELKKLNMTPIEMMDRAKKDKLPQMQVGFIDGVCLPIYETLSTHYPYFKPLLDECLNNRKHWKTL 887
            S+ R+ ++   +  L P  +HI  + + +  E  ++ PR+  +  + K  L+  +E+   +EL  DI+NDL++TSL +KIL  V ++ D DRCSLF+ +     G+K LVSK +DV+A + +   +  E    + VPWG GI+G+V E+G+T+NIPDAY D RFN +IDK TGY TKS+LCMPI+++   DG  E+I VAQ +NK  +GA     FT +DEK+ + YL FCGI I NA LF   ++E +R+R LL++   +FEEQ+ L  +V KIM   Q+LL+CERCSVLL++    P  K  F+K+F+L +     +  +  ++    SS   + IN  I   VA+TG  +NI DAY+DPRFD   D  SGF  R++LC+PI NS   IIGV Q+LN++DGKPF+  D+ LFEAF IFCG+ I+NT +Y++  K+ A+Q +ALDVLSYHAT S  E        +P      + +  FDD  L       A +RMF +L ++Q+F+IDY  LC W+LTV+KNYR V+YHNWRHAFNV Q MF  L     F+   T+ E LA++VGCLCHDLDHRGTNN FQ KS S LAQLYGTS  +EHHHF+H +MIL S G+ IF  LS +EY+  + +L+ +IL+TDL LYF +R ++  +V+   ++W   + R + RSMLMTACD+ A+ KPW++ ++VA LV  EFF+QGD E  +L +TP  + DR +KD+LP++Q+ +ID +C+P+Y+ L       KP+LD    NR  W+ L
Sbjct:  150 SSVRRRALLRKASSLPPTTAHI--LSALL--ESRVNLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEG-AAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRSS---DG--EIIGVAQAINKIPEGA----PFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVK--FTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTT-AGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL 908
The following BLAST results are available for this feature:
BLAST of TCONS_00063884-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PDE110.000e+046.13Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 1... [more]
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