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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00066683-protein ID=TCONS_00066683-protein|Name=TCONS_00066683-protein|organism=Clytia hemisphaerica|type=polypeptide|length=814bp
MAAAGIWDRLHPDEFTKLQEYTKYSKRRLKDVLQEFREGYHEGYDPEQPM
GYDGFKLFMSVYLGQSVSEELMQTLFWTFHKKVPRGDAKSPDLPNTILRK
ILVENGNVSQESLDQLNESSLSRIAKGARRATVVATATVVAGDIPRRAIS
EAELSRIDKTNDEMLTPITKRRLFLDTMTHLPMIEIKEIACYLSLLEGGD
VKDKLEFVFRVYDSDNNDYLDGEELESIVSQMLRVAEYLGWDTTALKPIL
TDMLADMDYDSDGQISLEEWVKGGMNNIPFLVLMGMEIKVDEEGKHQWAM
KHFKTQAFCNICHGVLAGFGRKQGLQCIFCRFTCHERCVQRSPNSCISTY
TQNKTKRKVTEMDHHWVEGNCPGKCTKCNKTIKNNCLTGLHCVWCSAQVH
NRCVTNMPVMCSLGPHKVHILPPICITPASKEKAEKVVKDKKNSVISYDG
IPMQITPLPDTKPLIAFINPKSGGRQGARLLNKFRYLLNPRQVFNLAEGG
PFPGLKFFAQVPDFRVLCCGGDGTAGWILATIDRLTSLKQRPPMAILPLG
TGNDLARCLGWGGGYEGGSLDKVLQKVLKSSVVMMDRWQIDCDNFEKTSI
EGDIMPQNIMNNYFSIGVDAAIALKFHLQREKNPEKFNSRFKNKLRYFQA
GTSEQLAATCTKLSNFLEIICDGKKLELPSLEGIAILNIPSIYGGANIWG
EPEKKRKRRKKSSGSSGDEPESLGSVSQDISDRKLEVVGLENSLYVGQII
AGVRQHGLRLAQCSTVVIKIMKTMPMQIDGEPWMQAPAQITINHKNQSPM
CVAPRNEKRGWFRF Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005509 | calcium ion binding |
| GO:0016301 | kinase activity |
| GO:0004143 | diacylglycerol kinase activity |
| GO:0003951 | NAD+ kinase activity |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
| GO:0035556 | intracellular signal transduction |
| GO:0008152 | metabolic process |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0008152 |
metabolic process |
| biological_process |
GO:0007205 |
protein kinase C-activating G-protein coupled receptor signaling pathway |
| molecular_function |
GO:0005509 |
calcium ion binding |
| molecular_function |
GO:0004143 |
diacylglycerol kinase activity |
| molecular_function |
GO:0016301 |
kinase activity |
| molecular_function |
GO:0003951 |
NAD+ kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR002048 | EF-hand domain | SMART | SM00054 | efh_1 | coord: 249..277
e-value: 1.0
score: 17.7
coord: 204..232
e-value: 0.16
score: 21.1 |
| IPR002048 | EF-hand domain | PFAM | PF13499 | EF-hand_7 | coord: 203..269
e-value: 6.2E-8
score: 32.9 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 245..280
score: 7.707 |
| IPR002048 | EF-hand domain | PROSITE | PS50222 | EF_HAND_2 | coord: 200..235
score: 11.333 |
| IPR002048 | EF-hand domain | CDD | cd00051 | EFh | coord: 204..273
e-value: 5.80237E-12
score: 61.4097 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | SMART | SM00046 | dagk_c4a_7 | coord: 463..588
e-value: 5.3E-56
score: 202.0 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | PFAM | PF00781 | DAGK_cat | coord: 464..576
e-value: 2.5E-25
score: 88.4 |
| IPR001206 | Diacylglycerol kinase, catalytic domain | PROSITE | PS50146 | DAGK | coord: 459..594
score: 44.314 |
| IPR000756 | Diacylglycerol kinase, accessory domain | SMART | SM00045 | dagk_c4b_2 | coord: 609..782
e-value: 1.6E-81
score: 286.8 |
| IPR000756 | Diacylglycerol kinase, accessory domain | PFAM | PF00609 | DAGK_acc | coord: 609..782
e-value: 9.1E-52
score: 175.5 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 296..346
e-value: 1.7E-7
score: 40.9
coord: 364..411
e-value: 1.7E-5
score: 34.3 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 296..347
e-value: 2.7E-10
score: 39.9
coord: 364..412
e-value: 2.6E-9
score: 36.7 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 296..346 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 364..411 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 363..411
score: 11.744 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 295..346
score: 13.597 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 364..411
e-value: 1.24942E-8
score: 51.3388 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 296..346
e-value: 2.35788E-12
score: 62.1244 |
| IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, domain 1 | GENE3D | 3.40.50.10330 | | coord: 458..602
e-value: 3.9E-33
score: 113.5 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 287..360
e-value: 3.0E-15
score: 55.3 |
| None | No IPR available | GENE3D | 1.10.238.10 | | coord: 205..283
e-value: 4.7E-12
score: 45.1 |
| None | No IPR available | GENE3D | 1.10.238.110 | | coord: 3..204
e-value: 3.2E-29
score: 101.2 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 361..412
e-value: 8.6E-10
score: 38.1 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 703..727 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 354..416 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 279..348 |
| IPR029477 | Diacylglycerol kinase type I, N-terminal | PFAM | PF14513 | DAG_kinase_N | coord: 7..199
e-value: 3.7E-31
score: 108.5 |
| IPR018247 | EF-Hand 1, calcium-binding site | PROSITE | PS00018 | EF_HAND_1 | coord: 258..270 |
| IPR018247 | EF-Hand 1, calcium-binding site | PROSITE | PS00018 | EF_HAND_1 | coord: 213..225 |
| IPR016064 | NAD kinase/diacylglycerol kinase-like domain | SUPERFAMILY | 111331 | NAD kinase/diacylglycerol kinase-like | coord: 728..795
coord: 459..701 |
| IPR011992 | EF-hand domain pair | SUPERFAMILY | 47473 | EF-hand | coord: 183..292 |
| IPR011992 | EF-hand domain pair | SUPERFAMILY | 47473 | EF-hand | coord: 7..91
coord: 181..207 |
Blast
BLAST of TCONS_00066683-protein vs. Swiss-Prot (Human)
Match: DGKB (Diacylglycerol kinase beta OS=Homo sapiens GN=DGKB PE=2 SV=2) HSP 1 Score: 761.14 bits (1964), Expect = 0.000e+0 Identity = 400/842 (47.51%), Postives = 525/842 (62.35%), Query Frame = 0
Query: 7 WDRLHPDEFTKLQEYTKYSKRRLKDVLQEFR-EGYHEGYDPE-------QPMGYDGFKLFMSVYLGQSVSEELMQTLFWTFHKKVPRGDAKSPDLPNTILRKILVENGNVSQESLDQLNESSLSRIAKGARRATVVATATVVAGDIPRRAISEAELSRIDKTNDEMLTPITKRRLFLDTMTHLPMIEIKEIACYLSLLEGGDVKDKLEFVFRVYDSDNNDYLDGEELESIVSQMLRVAEYLGWDTTALKPILTDMLADMDYDSDGQISLEEWVKGGMNNIPFLVLMGMEIKVDEEGKHQWAMKHFKTQAFCNICHGVLAGFGRKQGLQCIFCRFTCHERCVQRSPNSCISTYTQNKTKRKVTEMDHHWVEGNCPGKCTKCNKTIK-NNCLTGLHCVWCSAQVHNRCVTNMPVMCSLGPHKVHILPPICITPA-----------------SKEKAEKVVKDKKNSVI-----------SYDGIPMQITPLPDTKPLIAFINPKSGGRQGARLLNKFRYLLNPRQVFNLAEGGPFPGLKFFAQVPDFRVLCCGGDGTAGWILATIDRLTSLKQRPPMAILPLGTGNDLARCLGWGGGYEGGSLDKVLQKVLKSSVVMMDRWQIDCDNFEKTSIEGDIMPQNIMNNYFSIGVDAAIALKFHLQREKNPEKFNSRFKNKLRYFQAGTSEQLAATCTKLSNFLEIICDGKKLEL--PSLEGIAILNIPSIYGGANIWGEPEKKRKRR---KKSSG--SSGDEPESLGSVSQDISDRKLEVVGLENSLYVGQIIAGVRQHGLRLAQCSTVVIKIMKTMPMQIDGEPWMQAPAQITINHKNQSPMCVAP 804
W L P EF++LQ+Y +YS ++LKDVL+EF G Y+PE Q + ++GFKLFM +L + ++ LF +F K P P + L+ G R+ KGA P R S A + +I +K+I CYLSLLE G +DKLEF+FR+YD+D N +LD ELE+I+SQM+ VAEYL WD T L PIL +M+ ++DYD DG +SLEEW++GGM IP LVL+G+E V ++G+H W +KHF A+CN+C +L G G KQGL C FC++T HERCV R+P SCI TY K+KR M H+WVEGNCP KC KC+KT+K LTGLHCVWC +HN+C +++ C GP K HILPP I P S K EK + N VI + DG +Q+TP+P T PL+ F+NPKSGG+QG R+ KF+YLLNPRQV++L+ GP PGL FF VPDFRVL CGGDGT GW+L I++ ++ + PP+AILPLGTGNDLARCL WGGGYEG +L K+L+ + S+ +M+DRW+ + +K +GD +P +I+NNYFSIGVDA+IA +FH+ REK+PEKFNSR KNK YF+ GTSE +ATC KL +EI CDG +++L SLEGIAILNIPS++GG+N+WGE +K+R R KK S ++ + + L SQD+SD+ LEVVGLE ++ +GQI G++ G RLAQCS VVI+ K++PMQIDGEPWMQ P I I HKNQ+PM + P
Sbjct: 7 WAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKLFMKTFLEAELPDDFTAHLFMSFSNKFPHSS------PMVKSKPALLSGG---------------LRMNKGAI--------------TPPRTTSPANTCSPE------------------------VIHLKDIVCYLSLLERGRPEDKLEFMFRLYDTDGNGFLDSSELENIISQMMHVAEYLEWDVTELNPILHEMMEEIDYDHDGTVSLEEWIQGGMTTIPLLVLLGLENNVKDDGQHVWRLKHFNKPAYCNLCLNMLIGVG-KQGLCCSFCKYTVHERCVARAPPSCIKTYV--KSKRNTDVMHHYWVEGNCPTKCDKCHKTVKCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEK-ANVGKHPPVAILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPNDKDE-KGDPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVEIECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAKELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRTSKSLPMQIDGEPWMQTPCTIKITHKNQAPMLMGP 784
The following BLAST results are available for this feature:
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