TCONS_00068309-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00068309-protein
Unique NameTCONS_00068309-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length272

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00068309-protein ID=TCONS_00068309-protein|Name=TCONS_00068309-protein|organism=Clytia hemisphaerica|type=polypeptide|length=272bp
MEIVESNGELTPGNSNVCTQSHFESYLTTITLSRTVYQQYQISCGWWGSS
TCYRTRTQRISYYQQVTRYRVVYQDICCPGWAQQGDSCPIPVCNPVCVNG
ECAAPSTCSCQPGFDGSQCESDIDECALGSDGCQQNCVNTEGSFNCTCNP
GYFLSSDNTTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNK
TCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYRFSSDNTACEVDILAM
IAPWSNWTDWDKPCGGGFQFRT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042630XLOC_042630Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00068309TCONS_00068309Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001881EGF-like_Ca-bd_dom
IPR000742EGF-like_dom
IPR000152EGF-type_Asp/Asn_hydroxyl_site
IPR018097EGF_Ca-bd_CS
IPR013032EGF-like_CS
IPR011489EMI_domain
IPR009030Growth_fac_rcpt_
Vocabulary: Molecular Function
TermDefinition
GO:0005509calcium ion binding
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005509 calcium ion binding
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 122..162
e-value: 2.6E-10
score: 50.3
coord: 163..203
e-value: 1.3E-10
score: 51.3
coord: 204..244
e-value: 2.5E-10
score: 50.3
IPR001881EGF-like calcium-binding domainPFAMPF07645EGF_CAcoord: 122..161
e-value: 1.5E-9
score: 37.8
coord: 163..202
e-value: 1.6E-9
score: 37.7
coord: 204..243
e-value: 6.2E-10
score: 39.0
IPR000742EGF-like domainSMARTSM00181egf_5coord: 125..162
e-value: 2.1E-4
score: 30.6
coord: 166..203
e-value: 1.5E-4
score: 31.1
coord: 207..244
e-value: 0.0018
score: 27.5
coord: 92..120
e-value: 1.3
score: 18.1
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 163..203
score: 10.637
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 204..244
score: 9.786
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 122..162
score: 10.35
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 89..120
score: 8.548
NoneNo IPR availableGENE3D2.10.25.10coord: 90..122
e-value: 5.2E-5
score: 22.9
NoneNo IPR availableGENE3D2.10.25.10coord: 145..162
e-value: 2.0E-16
score: 59.1
coord: 185..205
e-value: 1.5E-16
score: 59.5
NoneNo IPR availableGENE3D2.10.25.10coord: 163..184
e-value: 1.1E-11
score: 44.1
coord: 123..144
e-value: 7.4E-10
score: 38.3
NoneNo IPR availableGENE3D2.10.25.10coord: 206..244
e-value: 1.9E-15
score: 56.2
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 178..189
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 137..148
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 219..230
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 163..187
IPR018097EGF-like calcium-binding, conserved sitePROSITEPS01187EGF_CAcoord: 204..228
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 108..119
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 146..161
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 108..119
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 228..243
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 187..202
IPR011489EMI domainPROSITEPS51041EMIcoord: 14..90
score: 9.318
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 49..164
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 136..245

Blast
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BLAST of TCONS_00068309-protein vs. Swiss-Prot (Human)
Match: MEGF6 (Multiple epidermal growth factor-like domains protein 6 OS=Homo sapiens GN=MEGF6 PE=1 SV=4)

HSP 1 Score: 136.346 bits (342), Expect = 3.667e-36
Identity = 97/271 (35.79%), Postives = 127/271 (46.86%), Query Frame = 0 
Query:   31 TLSRTVYQQYQISCGWWGSSTCYRTRTQRISYYQQV--TRYRVVYQDICCPGWAQQGD--SCPIPVCNP-VCVNGECAAPST---CSCQPGFDGSQCESDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNTTCEDIDECALGSDGCQQNCVN-TEGSFNCTCNPG-----------------------------------------YFLSSDNKTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYRFSSDNTAC---EVDIL 248
             LS TV   ++  CGW      +  RT     Y+QV  T  R V +  CC GW QQ D   C    C+  +C +G    P +   C C PGF G +C+ D+DEC   + GCQ  CVNT GS+ C C PG+ L +D+ TC  I+ CALG+ GCQ +CV  T     C C PG                                         Y L++D K CED+DECA G   C   C+NT+GSF C C+ GY   +D   C   E++I+
Sbjct:   65 ALSHTV-PVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLR--CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIV 332

HSP 2 Score: 102.449 bits (254), Expect = 1.578e-24
Identity = 62/148 (41.89%), Postives = 79/148 (53.38%), Query Frame = 0 
Query:  106 STCSCQPGF----DGSQCESDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNTTC-----EDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNKTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYRFSSDNTACE 244
            + C C  G+    DG  CE D+DECA G   C   C+NT+GSF C C+ GY L +D   C     E ++ C   + GC   C +T     CTC  GY L +D +TC D+D+CA  S  CQQ C N  G + C C  GYR S+D   CE
Sbjct:  266 ARCECHVGYQLAADGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE 411

HSP 3 Score: 102.449 bits (254), Expect = 2.058e-24
Identity = 61/143 (42.66%), Postives = 75/143 (52.45%), Query Frame = 0 
Query:  113 GFDGSQC---ESDI-DECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNTTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNKTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYRFSSDNTACEVDILAMI 251
            G DG QC   E +I + C   + GC   C +T     CTC  GY L +D  TC D+D+CA  S  CQQ C N  G + C C  GY LS+D   CED+DECA    GC+ +C N  GSF C+C  GYR   D   C      M+
Sbjct:  318 GADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV 459

HSP 4 Score: 80.4925 bits (197), Expect = 4.719e-17
Identity = 42/93 (45.16%), Postives = 54/93 (58.06%), Query Frame = 0 
Query:  122 DIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNTTCEDIDECALGSDGCQQNCVNTEGSFNCTCNPGYFLSSDNKTCEDIDECALGSDG 214
            D+D+CA  S  CQQ C N  G + C C  GY LS+D   CED+DECA    GC+ +C N  GSF C+C  GY L  D + C  ++E  +  DG
Sbjct:  372 DVDDCA-DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDG 463
The following BLAST results are available for this feature:
BLAST of TCONS_00068309-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MEGF63.667e-3635.79Multiple epidermal growth factor-like domains prot... [more]
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