TCONS_00069010-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069010-protein
Unique NameTCONS_00069010-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1116

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069010-protein ID=TCONS_00069010-protein|Name=TCONS_00069010-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1116bp
MSVSGIKSKRQSEKSSRKLNQKSKKLSRSWPNNIQKIFEDNHGPMVHNAT
ISRQPNFSSISSLAELQIEDSKHSHSARSHLSKLFGLFDWPWFATSKEET
KMENSSEDYPIHIPYKRFLNTSRVKLFSNNLEFDDKIDKLSHVNVLSLSK
NQFSSGDGIVYLPPSFSRLESIKELDLRGNPLKTFPEVILNLQELCTLNM
ADCQLEDVPRNITRLTKLKKLLLENNQIKLQNVVLDFPNLEQLYLTNNKI
SDISGIQMKSLLNLDVCENFIDQIPDVLTEKCCSLKQLVMKGNSITKIPK
SIKNLKALKWLDLSQNLLTKIPKDIGEVSTLQYLNLSWNDLTALPESITK
LNKLKKFYCGENPLQRPPYEIAKEGPDSIRSYFRALDGSAALTSKRLKLM
ILGNEKSGKTTLAKAIYSYEEPEPVEERTIGMDFFEWKDKNGLNVLIVDC
AGQKKYILTHQIFMQTGILFAVVLNLKDYNMTEEAYNTMIGEWIELILTS
VPNAVILIVPTFIDQCGSLEEIKQKCQHILTLVDKRRRKRQEIRIRYETR
SKGSFERAHKLKRDDIPTLPASFLFRNSVEEETKIHHLHKEPRGGEVSST
EAVTFTPSADNKSKVYLIPVSNRKHLHGLTLLREEIYRISNDETLCPNIN
REIPESWWKFEQLCNHEKDFKETLEVDELWKTVQEKKISFHTKEDMIEAL
KYFDSTSPILFLPCVKDVVFLNINWLFGAFKTIFRHDFNEFFVYKEEYED
MNPIEFCQEKRILMDQGKMGKKLFKYALWDVFKESEDNFNKVLALLMKFG
LIYNINEEEFLIPWYLPESIPSAIDSKSNNDQVYLTCLVSTIVRLPEGFF
QRFIVKVHSLNIFFHIRPWSNGFIGTYQFDDKNADPNHKKSPGVGKRDFK
LKLFHEKLKGFSQITVEGYANKQDIYHVWNMLNPVLEALEDFLQEWKGIK
YTIFTACPSCLQSTPSKQPFFWDLKLKHVYDDFEPIYCQLEGKRIDKWLV
YPPPSFSILDHLDDEKRNERLKANLSPEEKDNIAGKMGDRAEDLRAALGV
EKGLMEKISSDTNLRERVYQIIQFWEQKSKVITIERFMQCLNGMTPLPHE
IFEILLHVPEDECCSP
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042999XLOC_042999Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069010TCONS_00069010Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003591Leu-rich_rpt_typical-subtyp
IPR001611Leu-rich_rpt
IPR032675L_dom-like
IPR032171COR
IPR013684MIRO-like
IPR020859ROC_dom
IPR000488Death_domain
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0005525GTP binding
Vocabulary: Biological Process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007165 signal transduction
biological_process GO:0007264 small GTPase mediated signal transduction
molecular_function GO:0005525 GTP binding
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableSMARTSM00364LRR_bac_2coord: 328..347
e-value: 11.0
score: 13.5
coord: 305..324
e-value: 120.0
score: 5.5
coord: 169..188
e-value: 23.0
score: 11.0
NoneNo IPR availableSMARTSM00365LRR_sd22_2coord: 237..258
e-value: 21.0
score: 13.0
coord: 169..194
e-value: 110.0
score: 7.1
coord: 215..235
e-value: 150.0
score: 5.9
coord: 305..327
e-value: 120.0
score: 6.8
NoneNo IPR availableGENE3D3.40.50.300coord: 387..644
e-value: 2.4E-14
score: 52.5
NoneNo IPR availableGENE3D3.40.50.300coord: 910..1083
e-value: 0.32
score: 10.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..31
NoneNo IPR availableCDDcd01670Deathcoord: 1031..1091
e-value: 0.00524478
score: 35.3353
NoneNo IPR availableSUPERFAMILY52047RNI-likecoord: 118..371
IPR003591Leucine-rich repeat, typical subtypeSMARTSM00369LRR_typ_2coord: 328..351
e-value: 5.7
score: 15.3
coord: 169..191
e-value: 53.0
score: 7.3
coord: 192..215
e-value: 28.0
score: 9.6
coord: 258..281
e-value: 140.0
score: 3.9
coord: 305..326
e-value: 6.7
score: 14.7
coord: 237..257
e-value: 150.0
score: 3.6
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 260..318
e-value: 9.9E-9
score: 34.7
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 625..646
score: 4.793
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 239..260
score: 8.559
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 142..163
score: 5.456
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 261..281
score: 5.463
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 194..216
score: 5.34
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 330..351
score: 7.027
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 284..305
score: 6.341
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 217..238
score: 5.132
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 171..192
score: 6.303
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 307..328
score: 7.466
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 268..383
e-value: 1.2E-23
score: 82.8
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 242..267
e-value: 3.1E-4
score: 19.5
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 3..241
e-value: 2.8E-23
score: 81.5
IPR032171C-terminal of Roc (COR) domainPFAMPF16095CORcoord: 654..860
e-value: 3.2E-12
score: 46.6
IPR013684Mitochondrial Rho-likePFAMPF08477Roccoord: 398..514
e-value: 1.8E-11
score: 44.2
IPR020859Roc domainPROSITEPS51424ROCcoord: 390..573
score: 21.307
IPR000488Death domainPROSITEPS50017DEATH_DOMAINcoord: 1033..1092
score: 8.923
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 393..524

Blast
BLAST of TCONS_00069010-protein vs. Swiss-Prot (Human)
Match: MFHA1 (Malignant fibrous histiocytoma-amplified sequence 1 OS=Homo sapiens GN=MFHAS1 PE=1 SV=2)

HSP 1 Score: 216.468 bits (550), Expect = 1.511e-57
Identity = 224/943 (23.75%), Postives = 399/943 (42.31%), Query Frame = 0
Query:  136 KIDKLSHVNVLSLSKNQFSSGDGIVYLPPSFSRLESIKELDLRGNPLKTFPEVILNLQELCTLNMADCQLEDVPRNITRLTKLKKLLLENNQI-KLQNVVLDFPNLEQLYLTNNKI----SDISGIQMKSLLNLDVCENFIDQIPDVLTEKCCSLKQLVMKGNSITKIPKSIKNLKALKWLDLSQNLLTKIPKDIGEVSTLQYLNLSWNDLTALPESITKLNKLKKFYCGENPLQRPPYEIAKEGPDSIRSYFRALDGSAALTSKRLKLMILGNEKSGKTTLAKAIYSYE----------------EPEPVEERTIGMDFFEWK--DKNGLNVLIVDCAGQKKYILTHQIFMQTGILFAVVLNLKDYNMTEEAYNTMIGEWIELILTSVPNAVILIVPTFIDQCGSLEEIKQKCQHILTLVDKRRRKRQEIRIRYETRSKGSFERAHKLKRDDIPTLPASFLFRNSVEEETKIHHLHKEPRGGEVSSTEAVTFTPSADNKSKVY--LIPVSNRKHLHGLTLLREEIYRISNDETLCPNINREIPESWWKFEQLCNHEKDFKETLEVDELWKTVQEKKISFHTKEDMIEALKYFDSTSPILFL---PCVKDVVFLNINWLFGAFKTIFRHDFNEFFVY---------KEEYEDMNPIEFCQEKRILMDQGKMGKKLFKYALWDVFKESEDNFNKVLALLM------------------KFGLIYNINEEE----------FLIPWYLPESIPSA---IDSKSNNDQVY----LTCLVSTIVRLPEGFFQRFIVKVHSLNIFFHIRPWSNGFIGTYQFDDK-NADPNHKKSPGVGKRDFKLKLFHEKLKGFSQITVEGYANKQDIYHVWNMLNPVLEALEDFLQEWKGIKYTIFTACPSCL-QSTPSKQPFFWDLKLKHVYDDFEPIYCQLEG-KRIDKWLVYPP 1003
            ++  L+H+  L +S N+ +      +LP S S L  ++ LD+  N L  FP  +L L  L  L+++  +L  +P +I+ L  LK L L   ++  L     +  +LE L L NN +    +  S +Q   +LNL    N  ++ P  L      L++L +  N +T +P  I  L  L  L L  N +  +P  I E++ L+ L L  N +  LP+   +L+++  +   +NPL +PPYE+  +G   I +Y + L  S      RLKL+++G++ +GKT L   +                     P PV +   G++   W      GL  ++ D AG + Y +    F+  G L+ +V+NL  Y      + T +G ++  +   VP+AV+ IV T  D CG   E+++KC      +D  R+   + +   E  S+ +      L RD        F  R++           K  R           F    +++ ++   ++PVS R   H L  LR+++  ++    + PN++R +P SW   E+L  H +  +        W + +    +  T++ +  AL Y   +  +L+    P +K+ VF N+  L       F+ D +              K E E   P+      + L+   ++ + +  + L  +          V+ LL+                  K GL Y +N+ +          +  P Y+   +P A   I+  +   Q +    L    S     P G F R+ V+++S     H+   S+G    + +  K     +++ + GV + D               +++  +A+  +I+  W  + P++E L   LQEW G+ YT+   C  CL + +P+   F  +L  +   +    I C   G +R++  LVYPP
Sbjct:  153 QLGALAHLEELDVSFNRLA------HLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLS--SNLFEEFPAALL-PLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEERVEGCPGGGDKEKCYPPSPPPVSK---GIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYE--PRHFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGE-RELEEKC------LDIHRQIALQEKHDAEGLSRLAKVVDEALARD--------FELRSASPHAAYYGVSDKNLR------RRKAHFQYLLNHRLQILSPVLPVSCRDPRH-LRRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEEL--HFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDPSLLLHKLLLGTSGEGKAEGESSPPMARSTPSQELLRATQLHQYVEGFLLHGLLPA------HVIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSTAWYKFPCYVQNEVPHAEAWINGTNLAGQSFVAEQLQIEYSFPFTFPLGLFARYSVQINS-----HVVHRSDGKFQIFAYRGKVPVVVSYRPARGVLQPD--------------TLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPP 1032          
The following BLAST results are available for this feature:
BLAST of TCONS_00069010-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MFHA11.511e-5723.75Malignant fibrous histiocytoma-amplified sequence ... [more]
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