obscurin (polypeptide) - C. hemisphaerica

BLAST of obscurin vs. Swiss-Prot (Human)
Match: MYLK (Myosin light chain kinase, smooth muscle OS=Homo sapiens GN=MYLK PE=1 SV=4)

HSP 1 Score: 367.081 bits (941), Expect = 5.930e-102
Identity = 215/510 (42.16%), Postives = 307/510 (60.20%), Query Frame = 0

Query: 2361 ASNSYGTTKST--AMLYVEGLQTEYDTETEDEISD---PEPQPEREQINVRKD-AVENHYILKEELGRGKFGVVTKCQCKTSGTDFAAKFIKCRPT-ERKNVLMEIDIMNSLNHKRLINLVAAFESSRQIVLVLELVTGGELFEKLTEEEY-ISEKDVTFYMKQVLQGVQHMHEREILHLDLKPENIMLVNPHSTQIKLIDFGLARRYKKGDSLKVLFGTPEFMGPEVINYDQVTTATDMWSIGVITYVLLSGLSPFAGDNDSETLTNVTSGEWDFDDPVFEDISDEAKDFIMDLLVMRPSDRATVKDCLDHPWFMFKKFK----KKIRTDRLKAFTARRKWKKTITAVRSTNFLTR--LLTGIKTSQNATTPISAPTTPQSELKREDSAPTSPVSTSSSGPAWKRVEDLEEFDAPEFDKKLVDLKIRRGEVAHFQATFHGVEDERDTPEVAWKREGRILNESKHNHMTVIGNG-MHLKILNSQLDDTGRYTVRLENQHGAVECSAHLIV 2855
            A N YGT++ +  + L   G + E + + E E+SD    EP+ +   + +  +  V + Y ++E LG GKFG V +   K +   +A KF K     E++N+  EI IMN L+H +L+  V AFE    IV+VLE+V+GGELFE++ +E++ ++E++   YM+Q+ +GV+++H++ I+HLDLKPENIM VN   T+IKLIDFGLARR +   SLKVLFGTPEF+ PEVINY+ +  ATDMWSIGVI Y+L+SGLSPF GDND+ETL NVTS  WDFDD  F++ISD+AKDFI +LL     +R     CL HPW M K  K    KK+  DR+K + ARRKW+KT  AVR+   L+   +++G+   +++T    +PT+P +  K E     S     +       V + +    P F K + DL++  G  A F     G  D    PEV W ++ + + ES+H  +    +G   L I +   DD  +YT +  N  G   C+A LIV
Sbjct: 1406 AINVYGTSEPSQESELTTVGEKPE-EPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLM-KDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSST---GSPTSPLNAEKLESEEDVSQAFLEA-------VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD----PEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899          

HSP 2 Score: 242.276 bits (617), Expect = 1.050e-63
Identity = 151/493 (30.63%), Postives = 264/493 (53.55%), Query Frame = 0

Query: 2770 DLKIRRGEVAHFQATFHGVEDERDTPEVAWKREGRILNESKHNHMTVIGNGMHLKILNSQLDDTGRYTVRLENQHGAVECSAHLIVRDAPSPPAA-PVITQVLSTSALVQWRAPS-DGNAPIMSYRLQYRKLGDQEWSVFSDSIQQTITVVEDLEPDSSYRFRVSATNEIGSSEMGEQTDLVKTLAEDEGSKRESIDAPGARRLSRSLSITVPPSRLRSRTLGYEIKLKETNPENNYNFKEEIGRGKFAVVKKVGSKHSGETYAAKMVK-YDEDTVEITKKEFDIWKDLDHANLVLLHESFFVRKYLIFICDLVNGQDVLLFLANLP-SPTEDDVAGCMKQLLDALDYLHQMNICHLDIKPSNMVML---GSMLKLIDYGSARRVTSKGGEVGEMVGTIEFMSPEMISFDAVSSSTDMWSVGVLVYSLLSGLSPFTSDDEDETMSLITAVDYQFDPQVFDAISEEAKKFIKNLIVRIPEKRPSAIVCLEDPWL 3255
            D K+R GE         G +    T    W +  + + ES+H  +    NG  L IL ++ +  G YT+ +EN+ G+ +   +L V D P PPA  P  + + S+S  + W   S DG + + SY ++     ++ W   + + + T   V+DL PD  Y+FRV A N  G+SE  ++++L  T+ E     ++ ++               P    R+ T+  E K+ +      Y+ +E +G GKF  V ++  K + + +A K  K Y     E  ++E  I   L H  LV   ++F  +  ++ + ++V+G ++   + +     TE +    M+Q+ + ++Y+H+  I HLD+KP N++ +   G+ +KLID+G ARR+ +  G +  + GT EF++PE+I+++ +  +TDMWS+GV+ Y L+SGLSPF  D+++ET++ +T+  + FD + FD IS++AK FI NL+ +  + R     CL+ PWL
Sbjct: 1246 DQKVRAGESVELFGKVTGTQPITCT----WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELT-TVGEKPEEPKDEVEVSDDDEKE-------PEVDYRTVTINTEQKVSDF-----YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLEN-AGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWL 1719          

HSP 3 Score: 159.844 bits (403), Expect = 1.296e-38
Identity = 192/834 (23.02%), Postives = 322/834 (38.61%), Query Frame = 0

Query:  111 LPDEPIKKREGDKFEVRFKISGQPHPEVFFFKDEKPIEEKSKKVLIKREGEYYNFTIPRLESSDSGLYVVECENKNGTVEKEFEIEVEGKSKKA---PVAAPKPQLQ-SLVSASTNPN-----KPAFKIKLQDIEVVSFSAVRFEVVVKGDPEPEITWYKNNEIIDDDDRNFLQEEEEDGTCALVIREVSTNDRGTYKCMAKNRFGKAMTTAELFVEDHGFESDDSESELGGRSLPRTDDDDLTD-----DDLLDEEDELDHAQIILPMRDRHA-TIGSSAKFSCRAQSIKPHIPVEWYHDDKPVDLGCGRIKAAVAEEGELFTLNLRNVQMSDAGKYKIVFKLPNETLTSSANLNVDEGRKTEFGVSSRSSDTKKEPKATPPKPAPKTQRKPGQEE----------------------PTFVLEPKDKTVVEGNQLKLTASVNGKPTPLVEWYKENS-LLKSSSTIDIQATRNLHNMVIRKATTKDAGVYRCTARNEAGQCTVEVNIKIDTKSNKPKLSPNHPAFTRELEDFYEAEEGNDVEMKVEFTGKPKPRIHWEKNGKNIVSIKRVKIHEEDGASQLLIKALRDTDFGDYSCTISNFHGNTKSTSCLRLC-SDGTPDIHINTPSPPPPPISSTTNQECSNLDEYDATDDEVAVITD-----------RRNDQNTSNDIGMKL------LQIKELHPGLNREVTRHKF--PGACGIDVVVMPATPRDSPVSGAQPVIKTKPEDLDLNIGEKALFELQLADDTDLAKVNVSWSKNGQILFG-SGRTRIWNKDYSFFLEISKVDVDDESLYEVRVRNDYGEVMCDVQLLVND 885
            LP   +  +EG   +   ++ G P P+V + ++ +PI    + +L       ++  I  +   D G Y  E  N +G  +   E+ VEG   K    PV +     + S  +  T P+      P F  KL  + V      RF   + G P+P++TW K N  +    R  +   E++G   L I  V+ +D G Y C+  N  GKA  +AEL ++  G +S +       RS  R      +D      +++ +E +LD  +     ++  +   G S  ++  +Q   P         D P                       R    +       V +  + ++T  A     E R    GV S S + +K P   PP+PA    R+PG                         P F  +P+ + V E   +K    V+G P P V W+ E + + +   +I++      H + + KA T+D+G Y CTA N  GQ +    ++++    +  +    P+F+  L+D     EG D  ++    G P PRI W  NG+    I+  +   E G ++L I+     D G Y+C   N  G    ++ + +     +       P  P  P +    Q  S+L   D +   + V                N+   S D   +       L I+E+ P      T   +   G      V+    P D    G QP   +KP  +  ++G+  L    +A D       V W ++G+ L   +G   +   +  F L + KV       YE+ ++N  GE  C V L++ +
Sbjct:   37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ--GLDSAN-------RSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSP-----------------------RTAPQTP------VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRP--APPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE----RLAVMEVAPSFSSVLKDC-AVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD----GTQPWFISKPRSVTASLGQSVLISCAIAGD---PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813          

HSP 4 Score: 93.9745 bits (232), Expect = 1.170e-18
Identity = 109/426 (25.59%), Postives = 161/426 (37.79%), Query Frame = 0

Query:   19 IKEGEPFELNFEVSDDSK---AIFYKGDNRIDDMGRAVVTRMGRTFRFYIPEVKESDSGQYIMEVQGESGITNKSFKIKVQGKPKKSPIPTIDVDLPDEPIKKREGDKFEVRFKISGQPHPEVFFFKDEKPIEEKSKKVLIKREGEYYNFTIPRLESSDSGLYVVECENKNGTVEKEFEIEVEGK--SKKAPVAAPKPQLQSLVSASTNPNKPAFKIKLQDIEVVSFSAVRFEVVVKGDPEPEITWYKN-NEIIDDDDRNFLQEEEEDGTCALVIREVSTNDRGTYKCMAKNRFGKAMTTAELFVEDHGFESDDSESELGGRSLPRTDDDDLTDDDLLDEEDELDHAQIILPMRDRHATIGSSAKFSCRAQSIKPHIPVEWYHDDKPVDLGCGRIKAAVAEEGELFTLNLRNVQMSDAGKYKIVFK 438
            +KE +  +   EVS   K   A F +G       G   V     +    + + +  DSG Y        G  + S+ ++V+        P+    L D  +   EG  F ++  + G P P + +  + +PI+          E       I      D G Y    EN  G V     + V  K  S+K+    P         A + P  P F   L D++V+  S V   V V G+P PE+ W  N NEI + +D +F Q   +   C   I+EV   D GTY C A N  G+  T A L V+                                 E  +      I   R   A++G S   SC A +  P   V W  D K +    G  +  V +  ++FTL L+ VQ   AG+Y+I+ K
Sbjct:  425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI--EGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP--------VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC---IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---------------------------------EPHDGTQPWFISKPRSVTASLGQSVLISC-AIAGDPFPTVHWLRDGKALCKDTGHFE--VLQNEDVFTLVLKKVQPWHAGQYEILLK 797          

HSP 5 Score: 92.0485 bits (227), Expect = 4.924e-18
Identity = 44/94 (46.81%), Postives = 57/94 (60.64%), Query Frame = 0

Query: 2286 PYFTRELENSFVVEGGAAKFICRCHGNPDPEVVWYKEKEKIVESKQFSILFDADENCVLIITQSNHDTAGSYMCVASNSYGTTKSTAMLYVEGL 2379
            PYF++ + +  VVEG AA+F C+  G PDPEVVW+K+ + I ES+ F I +D D NC LII+    D    Y C A NS G    TA L VE +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1902          

HSP 6 Score: 85.1149 bits (209), Expect = 6.331e-16
Identity = 40/94 (42.55%), Postives = 61/94 (64.89%), Query Frame = 0

Query:  225 KPAFKIKLQDIEVVSFSAVRFEVVVKGDPEPEITWYKNNEIIDDDDRNFLQEEEEDGTCALVIREVSTNDRGTYKCMAKNRFGKAMTTAELFVE 318
            KP F   ++D+EVV  SA RF+  ++G P+PE+ W+K+++ I +  R+F  + +EDG C+L+I +V  +D   Y C A N  G+A  TAEL VE
Sbjct: 1808 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES-RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900