TCONS_00070979-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00070979-protein
Unique NameTCONS_00070979-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1107

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00070979-protein ID=TCONS_00070979-protein|Name=TCONS_00070979-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1107bp
MSSKGIYEADGKKFLANHLKADTFVAPLFAHVAEDTDLEELAKTHPWLLE
KKLVVKPDQMIKRRGKLGLLKVNTDWEGVKEWLAEKRGKETQVGKVSGLL
KKFIIEPFIEHDEKEEMYLCIYTQRDEDVILFHHEGGIDIGDVDSKALKM
TIPIDGETNTDAIKSTLLSNVAQSDQDRVAGFIFSIFDLYKDLFFTYLEI
NPLVVKTDSIYVLDLAAKIDQTAEFLCSAKWGKIGFPPPFGREAYPEEAF
IAELDAKSGASLKLTVLNKAGRVWTMVAGGGASVVYSDTIADLGGGDEMA
NYGEYSGAPSETQTFEYAKTILKLMTEGEPHPDGKVLIIGGGIANFTNVS
ATFAGIVKALQLYQQELIRHKVKIFVRRGGPNYQEGLRIMRELGATLGVP
MHVFGTETHMTAIVGMALGKTEIPRTSVCDSNDAASKMFFNTYDESAPAS
GSGTPKRKASNELTSSQESDKKKLCKANSGDFVMVQHSETPPSVLFTKDT
KAIVWGLQHRAVQGMLDFDYVCQRKEPSVKAMVYPFSGNHNQKFYYGHKE
IMIPVFSKMAVAVEKIPDASVLVNFASLRSAYDATVDALQYPQFRTVAII
AEGIPERITQQLNKKAKDKGVIIIGPATVGGIKPGCFKIGNTGGMLDNIL
ASKLYRPGSVGYISRSGGLSNELNNIIARNTDGVNEGLAIGGDRYPGTVF
IDHFLRYEANPEIKMMVLLGEVGGNDEYEICRAIKDGRITKPVVGWCIGT
CASVLTTEVQFGHANACANSFAETAVAKNQALRDAGAAVPDSFNDLDKTI
KSVYEKLVMDGTIVPRPEVRPPTVPMDYSWAQELGLIRKPSSFISAICDE
RGQELLYAGTKISDVFKDDLGIGGVLGLLWFQRRLPKYASKFIEMCLMIT
ADHGPAVSGAHNTIVTSRAGKDLISSLCSGLLTIGDRFGGALDGAAKIFS
EAYDSGTAPMEFVNSMRKKGKLILGIGHKIKSLNNPDARVVIMKNYMKEH
FPQTDLLDYALEVEQITTSKKPNLILNVDGCIAVGFVDLLRNCGCFTRSE
ADEYVQNGALNGLFVLGRSVGFIGHHLDQKRLKQGLYRHPWDDISYIIPE
SAQAPFE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044115XLOC_044115Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00070979TCONS_00070979Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR016102Succinyl-CoA_synth-like
IPR014608ATP-citrate_synthase
IPR005811CoA_ligase
IPR003781CoA-bd
IPR032263Citrate-bd
IPR002020Citrate_synthase
IPR016143Citrate_synth-like_sm_a-sub
IPR016142Citrate_synth-like_lrg_a-sub
IPR013650ATP-grasp_succ-CoA_synth-type
IPR017866Succ-CoA_synthase_bsu_CS
IPR033847Citrt_syn/SCS-alpha_CS
IPR011761ATP-grasp
IPR016040NAD(P)-bd_dom
Vocabulary: Molecular Function
TermDefinition
GO:0003878ATP citrate synthase activity
GO:0003824catalytic activity
GO:0048037cofactor binding
GO:0046912transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
GO:0046872metal ion binding
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006101citrate metabolic process
GO:0006085acetyl-CoA biosynthetic process
GO:0008152metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006085 acetyl-CoA biosynthetic process
biological_process GO:0006101 citrate metabolic process
biological_process GO:0008152 metabolic process
molecular_function GO:0005524 ATP binding
molecular_function GO:0003878 ATP citrate synthase activity
molecular_function GO:0003824 catalytic activity
molecular_function GO:0048037 cofactor binding
molecular_function GO:0046872 metal ion binding
molecular_function GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016102Succinyl-CoA synthetase-likeGENE3D3.40.50.261coord: 624..822
e-value: 7.6E-38
score: 129.2
IPR016102Succinyl-CoA synthetase-likeGENE3D3.40.50.261coord: 255..418
e-value: 1.2E-19
score: 70.3
IPR016102Succinyl-CoA synthetase-likeSUPERFAMILY52210Succinyl-CoA synthetase domainscoord: 260..396
NoneNo IPR availableGENE3D3.40.50.720coord: 490..623
e-value: 3.8E-25
score: 88.3
NoneNo IPR availableGENE3D3.30.470.20coord: 78..240
e-value: 1.5E-38
score: 131.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 446..471
NoneNo IPR availableCDDcd06100CCL_ACL-Ccoord: 881..1096
e-value: 3.95987E-80
score: 260.963
NoneNo IPR availableSUPERFAMILY56059Glutathione synthetase ATP-binding domain-likecoord: 33..237
IPR014608ATP-citrate synthasePIRSFPIRSF036511ATP_citrt_syncoord: 1..1104
e-value: 0.0
score: 1887.8
IPR005811ATP-citrate lyase/succinyl-CoA ligasePFAMPF00549Ligase_CoAcoord: 663..787
e-value: 1.4E-13
score: 50.9
IPR003781CoA-bindingPFAMPF02629CoA_bindingcoord: 497..603
e-value: 3.1E-7
score: 30.9
IPR032263ATP-citrate synthase, citrate-binding domainPFAMPF16114Citrate_bindcoord: 242..420
e-value: 3.7E-90
score: 300.1
IPR002020Citrate synthasePFAMPF00285Citrate_syntcoord: 870..1082
e-value: 1.8E-17
score: 63.4
IPR002020Citrate synthaseSUPERFAMILY48256Citrate synthasecoord: 787..1098
coord: 621..742
IPR016143Citrate synthase-like, small alpha subdomainGENE3D1.10.230.10coord: 957..1039
e-value: 2.9E-15
score: 55.7
IPR016142Citrate synthase-like, large alpha subdomainGENE3D1.10.580.10coord: 823..956
e-value: 9.0E-18
score: 63.7
IPR013650ATP-grasp fold, succinyl-CoA synthetase-typePFAMPF08442ATP-grasp_2coord: 37..205
e-value: 1.0E-7
score: 31.6
IPR017866Succinyl-CoA synthetase, beta subunit, conserved sitePROSITEPS01217SUCCINYL_COA_LIG_3coord: 271..296
IPR033847ATP-citrate lyase/succinyl-CoA ligase, conserved sitePROSITEPS01216SUCCINYL_COA_LIG_1coord: 664..693
IPR011761ATP-grasp foldPROSITEPS50975ATP_GRASPcoord: 16..230
score: 8.805
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 494..626

Blast
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BLAST of TCONS_00070979-protein vs. Swiss-Prot (Human)
Match: ACLY (ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3)

HSP 1 Score: 1547.72 bits (4006), Expect = 0.000e+0
Identity = 734/1109 (66.19%), Postives = 886/1109 (79.89%), Query Frame = 0 
Query:    1 MSSKGIYEADGKKFLANHLKADTFVAPLF--AHVAEDTDLEELAKTHPWLLEKKLVVKPDQMIKRRGKLGLLKVNTDWEGVKEWLAEKRGKETQVGKVSGLLKKFIIEPFIEHDEKEEMYLCIYTQRDEDVILFHHEGGIDIGDVDSKALKMTIPIDGETNTDAIKSTLLSNVAQSDQDRVAGFIFSIFDLYKDLFFTYLEINPLVVKTDSIYVLDLAAKIDQTAEFLCSAKWGKIGFPPPFGREAYPEEAFIAELDAKSGASLKLTVLNKAGRVWTMVAGGGASVVYSDTIADLGGGDEMANYGEYSGAPSETQTFEYAKTILKLMTEGEPHPDGKVLIIGGGIANFTNVSATFAGIVKALQLYQQELIRHKVKIFVRRGGPNYQEGLRIMRELGATLGVPMHVFGTETHMTAIVGMALGKTEIPRTSVCDSNDAASKMFFNTYDESAPASGSGTPKRKASNELTSSQESDKKKLCKANSGDFVMVQHSETPP-------SVLFTKDTKAIVWGLQHRAVQGMLDFDYVCQRKEPSVKAMVYPFSGNHNQKFYYGHKEIMIPVFSKMAVAVEKIPDASVLVNFASLRSAYDATVDALQYPQFRTVAIIAEGIPERITQQLNKKAKDKGVIIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVGYISRSGGLSNELNNIIARNTDGVNEGLAIGGDRYPGTVFIDHFLRYEANPEIKMMVLLGEVGGNDEYEICRAIKDGRITKPVVGWCIGTCASVLTTEVQFGHANACANSFAETAVAKNQALRDAGAAVPDSFNDLDKTIKSVYEKLVMDGTIVPRPEVRPPTVPMDYSWAQELGLIRKPSSFISAICDERGQELLYAGTKISDVFKDDLGIGGVLGLLWFQRRLPKYASKFIEMCLMITADHGPAVSGAHNTIVTSRAGKDLISSLCSGLLTIGDRFGGALDGAAKIFSEAYDSGTAPMEFVNSMRKKGKLILGIGHKIKSLNNPDARVVIMKNYMKEHFPQTDLLDYALEVEQITTSKKPNLILNVDGCIAVGFVDLLRNCGCFTRSEADEYVQNGALNGLFVLGRSVGFIGHHLDQKRLKQGLYRHPWDDISYIIPE 1100
            MS+K I E  GK+ L   +   + +   F  A V  DTD   L + HPWLL + LVVKPDQ+IKRRGKLGL+ VN   +GVK WL  + G+E  VGK +G LK F+IEPF+ H + EE Y+CIY  R+ D +LFHHEGG+D+GDVD+KA K+ + +D + N + IK  LL +  +  ++ +A FI  +F+ Y+DL+FTYLEINPLVV  D +YVLDLAAK+D TA+++C  KWG I FPPPFGREAYPEEA+IA+LDAKSGASLKLT+LN  GR+WTMVAGGGASVVYSDTI DLGG +E+ANYGEYSGAPSE QT++YAKTIL LMT  E HPDGK+LIIGG IANFTNV+ATF GIV+A++ YQ  L  H+V IFVRRGGPNYQEGLR+M E+G T G+P+HVFGTETHMTAIVGMALG   IP      ++ A      N          SG+    A +   S  ES   ++  A      M Q S   P       + LF++ TKAIVWG+Q RAVQGMLDFDYVC R EPSV AMVYPF+G+H QKFY+GHKEI+IPVF  MA A+ K P+  VL+NFASLRSAYD+T++ + Y Q RT+AIIAEGIPE +T++L KKA  KGV IIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSV Y+SRSGG+SNELNNII+R TDGV EG+AIGGDRYPG+ F+DH LRY+  P +KM+V+LGE+GG +EY+ICR IK+GR+TKP+V WCIGTCA++ ++EVQFGHA ACAN  +ETAVAKNQAL++AG  VP SF++L + I+SVYE LV +G IVP  EV PPTVPMDYSWA+ELGLIRKP+SF+++ICDERGQEL+YAG  I++VFK+++GIGGVLGLLWFQ+RLPKY+ +FIEMCLM+TADHGPAVSGAHNTI+ +RAGKDL+SSL SGLLTIGDRFGGALD AAK+FS+A+DSG  PMEFVN M+K+GKLI+GIGH++KS+NNPD RV I+K+Y+++HFP T LLDYALEVE+ITTSKKPNLILNVDG I V FVD+LRNCG FTR EADEY+  GALNG+FVLGRS+GFIGH+LDQKRLKQGLYRHPWDDISY++PE
Sbjct:    1 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTR-EKHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTA--NFLLN---------ASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPE 1097
The following BLAST results are available for this feature:
BLAST of TCONS_00070979-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACLY0.000e+066.19ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 ... [more]
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