TCONS_00071027-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00071027-protein
Unique Name	TCONS_00071027-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	742

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00071027-protein ID=TCONS_00071027-protein|Name=TCONS_00071027-protein|organism=Clytia hemisphaerica|type=polypeptide|length=742bp
MKKTQRSSANSKDTKKALSQEIMAGSVVKKYDELIRCTNVLTEGIETEFV
KFVKHQEDSRKKWQHVEEENHEMKKYMAKYKASKDTLDIQLNMARHQLDA
EIKKRLKAEQSVDHMARQLQLIKELLLDKDGSGDTKLVFDKLQQQINDTV
GQRVDNEQQADLINQSYTLDESSFDLPASEYDNTEDDILDLTGGSVLGNG
RRRSNKRGLPTAPPLNEVDSTESELSTYQVKKTRVSEEKPARKFKKKRTR
YYVPEEKVYRQVHKTIETHVTVTGGRSPAKSPKKAERLDKDFSRPPSQSG
KRPPSRGHVRAQSTTDMSDEYDKENCSTPRPFTLTRHQQQQPPLQPKPEN
HHSNNRHHHHQSFQHPSPSKPPINKGLTKQMTVPNLYPNLDSMLTPDPKK
KFNTLNTPRSGKKLQAHQFVPKVAVRMESCGPCNKKVRFGSHISKCKECK
AMCHNECRDKVPLPCIPSKDTPGRKREGAIESYISGSGLQVPKIVTTCIE
EVEKRGLRELGIYRVPGMDRDVKELKEKFLRGRNPDLNKINDIHVVCGCL
KDFLRGLSEPLVTFTLHESFMVSAALTDEDDSLSGMYQCVSELPQANRET
LAAIVIHLQKVATSTETQMSVSNLSKVFGPTLIGHRSSNPTHMEMLDDTK
AQPVVVTRLLEMPSDYWSQLLSGGPHVRTPPYNPHYASATPTTPECKPVP
TSRLGAIDDMTPSRSDRKFNAMNPRHASSKDPKSHRFFNSPS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_044133	XLOC_044133	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00071027	TCONS_00071027	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000198	RhoGAP_dom
IPR002219	PE/DAG-bd
IPR008936	Rho_GTPase_activation_prot

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction
GO:0035556	intracellular signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035556	intracellular signal transduction
biological_process	GO:0007165	signal transduction

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 66..86
None	No IPR available	GENE3D	1.10.555.10		coord: 479..672 e-value: 3.3E-49 score: 166.4
None	No IPR available	GENE3D	3.30.60.20		coord: 415..478 e-value: 8.5E-10 score: 37.8
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 193..224
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 677..742
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 269..408
None	No IPR available	CDD	cd04382	RhoGAP_MgcRacGAP	coord: 477..667 e-value: 1.19175E-84 score: 267.237
None	No IPR available	SUPERFAMILY	57889	Cysteine-rich domain	coord: 411..467
IPR000198	Rho GTPase-activating protein domain	SMART	SM00324	RhoGAP_3	coord: 489..668 e-value: 1.3E-53 score: 194.1
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 492..638 e-value: 3.1E-41 score: 140.6
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 478..667 score: 39.845
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	SMART	SM00109	c1_12	coord: 417..465 e-value: 4.6E-6 score: 36.1
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PFAM	PF00130	C1_1	coord: 417..466 e-value: 2.5E-6 score: 27.2
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PROSITE	PS00479	ZF_DAG_PE_1	coord: 417..465
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PROSITE	PS50081	ZF_DAG_PE_2	coord: 416..465 score: 10.115
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	CDD	cd00029	C1	coord: 417..465 e-value: 4.4497E-9 score: 52.4944
IPR008936	Rho GTPase activation protein	SUPERFAMILY	48350	GTPase activation domain, GAP	coord: 487..668

Blast

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BLAST of TCONS_00071027-protein vs. Swiss-Prot (Human)
Match: RGAP1 (Rac GTPase-activating protein 1 OS=Homo sapiens GN=RACGAP1 PE=1 SV=1)

HSP 1 Score: 311.227 bits (796), Expect = 3.398e-96
Identity = 155/330 (46.97%), Postives = 217/330 (65.76%), Query Frame = 0

Query:  389 NLDSMLTP---DPKKKFNTLNTPRSGKKLQAHQFVPKVAVRMESCGPCNKKVRFGSHISKCKECKAMCHNECRDKVPLPCIPSK-DTPGRKREGAIESYISGSGLQVPKIVTTCIEEVEKRGLRELGIYRVPGMDRDVKELKEKFLRGRN-PDLNKINDIHVVCGCLKDFLRGLSEPLVTFTLHESFMVSAALTDEDDSLSGMYQCVSELPQANRETLAAIVIHLQKVATSTETQMSVSNLSKVFGPTLIGHRSSNPTHMEMLDDTKAQPVVVTRLLEMPSDYWSQLLSGGPHVRTPPYNPHY------ASATPTTPECKPVPTSRLGAI 707
            N DS L     +P+ + +++ TP+S   ++ H FV K  ++ ESC PC K+++FG    KC++C+ + H ECRD+ PLPCIP+   TP +  EG +  ++S +   +P IV  C+ E+E+RGL E G+YR+ G DR VKELKEKFLR +  P L+K++DIH +C  LKDFLR L EPL+TF L+ +FM +A +TDED+S++ MYQ V ELPQANR+TLA ++IHLQ+VA S  T+M V+NL+KVFGPT++ H   NP  + ML D K QP VV RLL +P +YWSQ +     V     +P +      A +TP TP+ K    S LG +
Sbjct:  256 NSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWSQFM----MVEQENIDPLHVIENSNAFSTPQTPDIK---VSLLGPV 578

HSP 2 Score: 90.1225 bits (222), Expect = 1.061e-18
Identity = 63/199 (31.66%), Postives = 101/199 (50.75%), Query Frame = 0

Query:   21 EIMAGSVVKKYDELIRCTNVLTEGIETEFVKFVKHQEDSRKKWQHVEEENHEMKKYMAKYKASKDTLDIQLNMARHQLDAEIKKRLKAEQSVDHMARQLQLIKELLLDKDGSGDTKLVFDKLQQQINDTVGQRVDNEQQADLINQSYTLDESSFDLPASEYDNTEDDILDLTGGSVLG-----NGRRRSNKRGLPTAPP 214
            + M  +V   +++L+R   +L+EG E +F++  K  ED RKKWQ  + E  + K  + K +  +  LD++L  AR+Q+D EIK+R +AE   + + RQ+QLI+E+L+  D SG  +L  ++         GQ   +      ++   T+DES   L    +D T D+ LD     V         +RRS  R     PP
Sbjct:    2 DTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLM-CDTSGSIQLSEEQKSALAFLNRGQPSSSNAGNKRLS---TIDESGSILSDISFDKT-DESLDWDSSLVKTFKLKKREKRRSTSRQFVDGPP 195

The following BLAST results are available for this feature:

BLAST of TCONS_00071027-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00071027-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
RGAP1	3.398e-96	46.97	Rac GTPase-activating protein 1 OS=Homo sapiens GN...	[more]

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TCONS_00071027-protein (polypeptide) - C. hemisphaerica