frizzled receptor 1 (polypeptide) - C. hemisphaerica

Overview
Namefrizzled receptor 1
Unique NameTCONS_00071204-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length556

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00071204-protein ID=TCONS_00071204-protein|Name=frizzled receptor 1|organism=Clytia hemisphaerica|type=polypeptide|length=556bp
MDKNFEIMRLFLFGIFILMPTVTSNKVCQHFPKEKFELCKEMPYNTTLFP
NILDNRNIEEAIKEMEVFSPMIKVACSELLQTFLCSVYAPFCREDTAGIM
YPCRSICEKAKEGCSELMNRFQFKWPQHLDCKNFPENTGNFKSLCLDETV
LSLAYRKKPKENPGGDTPGEYYGKFNCPPHQMKDEKHYNFMGQEGCASKC
EPIYFEKTEKEFARNWVLFWSIVCMLSTAFTLLTFVVDMPRFRYPERPII
FLSGCYFMVSTAFLAGPLSGNAVSCHTQLKNRRGEIELLNQGTENASCTV
VFMIIYFFLMAASIWWVILTLTWFLAAGLKWGHEAIEASSQYFHAAAWAI
PAAKTIAILAMNKVDGDALSGICFVGGNNVGALQGFVIVPLLICLILGTF
FLFSGFLALIRIRKVLKDDHSLRTDKLTRLMIRIGIFSVLYSLPAIIVIA
CLFYEQSYRDTWNESWIKSYMDMLRDCGDKECKDFIGKARPDFTVFIIKY
LMLLMVGITSGFWIWSGKTIQSWKMFYYNKILHRPLPRHNDSKDGSSRAA
FLSRPM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044260XLOC_044260Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00071204TCONS_00071204Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000539Frizzled
IPR020067Frizzled_dom
IPR017981GPCR_2-like
Vocabulary: Biological Process
TermDefinition
GO:0007166cell surface receptor signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0004888transmembrane signaling receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007166 cell surface receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0016020 membrane
molecular_function GO:0005515 protein binding
molecular_function GO:0004888 transmembrane signaling receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000539Frizzled proteinPRINTSPR00489FRIZZLEDcoord: 430..451
score: 62.0
coord: 300..324
score: 64.8
coord: 216..238
score: 46.78
coord: 388..410
score: 39.3
coord: 495..515
score: 58.29
coord: 343..366
score: 60.17
coord: 244..266
score: 61.74
IPR000539Frizzled proteinSMARTSM01330Frizzled_2coord: 203..534
e-value: 2.5E-186
score: 635.0
IPR000539Frizzled proteinPFAMPF01534Frizzledcoord: 204..527
e-value: 1.5E-134
score: 448.1
IPR020067Frizzled domainSMARTSM00063FRI_4coord: 27..150
e-value: 1.5E-31
score: 120.8
IPR020067Frizzled domainGENE3D1.10.2000.10coord: 20..151
e-value: 4.3E-33
score: 113.8
IPR020067Frizzled domainPFAMPF01392Fzcoord: 28..137
e-value: 1.7E-26
score: 93.0
IPR020067Frizzled domainPROSITEPS50038FZcoord: 23..148
score: 24.119
IPR020067Frizzled domainSUPERFAMILY63501Frizzled cysteine-rich domaincoord: 32..140
NoneNo IPR availableGENE3D1.20.1070.10coord: 204..467
e-value: 8.6E-16
score: 57.2
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 210..522
score: 35.842

Blast
BLAST of frizzled receptor 1 vs. Swiss-Prot (Human)
Match: FZD7 (Frizzled-7 OS=Homo sapiens GN=FZD7 PE=1 SV=2)

HSP 1 Score: 498.049 bits (1281), Expect = 1.101e-171
Identity = 258/538 (47.96%), Postives = 350/538 (65.06%), Query Frame = 0
Query:   21 TVTSNKVCQHFPKEKFELCKEMPYNTTLFPNILDNRNIEEAIKEMEVFSPMIKVACSELLQTFLCSVYAPFCREDTAGIMYPCRSICEKAKEGCSELMNRFQFKWPQHLDCKNFPENTGNFKSLCLDETV---------LSLAYRKKP--------KENPGG-DTPGEYYGKFNCPPHQMKDEKH--YNFMGQEGCASKCEP------IYFEKTEKEFARNWVLFWSIVCMLSTAFTLLTFVVDMPRFRYPERPIIFLSGCYFMVSTAFLAGPLSGNAVSCHTQLKNRRGEIELLNQGTENASCTVVFMIIYFFLMAASIWWVILTLTWFLAAGLKWGHEAIEASSQYFHAAAWAIPAAKTIAILAMNKVDGDALSGICFVGGNNVGALQGFVIVPLLICLILGTFFLFSGFLALIRIRKVLKDDHSLRTDKLTRLMIRIGIFSVLYSLPAIIVIACLFYEQSYRDTWNESWIKSYMDMLRDCGDKECKDFIGK---ARPDFTVFIIKYLMLLMVGITSGFWIWSGKTIQSWKMFYYN 529
            +V  +  CQ        LC ++ YN T+ PN+L + N E+A  E+  F P++KV CS  L+ FLCS+YAP C      I  PCRS+CE+A++GC  LMN+F F+WP+ L C+NFP +      +C+ +              AY   P           PG  D  G     F+CP  Q+K   +  Y F+G+  C + CEP      +YF++ E+ FAR WV  WS++C  ST FT+LT++VDM RF YPERPIIFLSGCYFMV+ A +AG L  +   C  +  +       + QGT+   CT++FM++YFF MA+SIWWVIL+LTWFLAAG+KWGHEAIEA+SQYFH AAWA+PA KTI ILAM +VDGD LSG+C+VG ++V AL+GFV+ PL + L +GT FL +GF++L RIR ++K D + +T+KL +LM+RIG+FSVLY++PA IV+AC FYEQ++R+ W  +W      +L+ C         G      PDFTVF+IKYLM ++VGIT+GFWIWSGKT+QSW+ FY+ 
Sbjct:   42 SVPDHGFCQPI---SIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIP-PCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAG--EICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCP-RQLKVPPYLGYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSD--DGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGT-KTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTW------LLQTCKSYAVPCPPGHFPPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHR 563          
The following BLAST results are available for this feature:
BLAST of frizzled receptor 1 vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FZD71.101e-17147.96Frizzled-7 OS=Homo sapiens GN=FZD7 PE=1 SV=2[more]
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