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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00002252-protein ID=TCONS_00002252-protein|Name=TCONS_00002252-protein|organism=Clytia hemisphaerica|type=polypeptide|length=874bp
MVFKILFICIQFGFLSAQLDIVTDETPLEDRGACISNPCLHNGMCTVTSN
GFICTCVNSYIGVNCERRADDCPRDLSMKCVHGVCKLDMNGNPKCICKEG
FEGPICSLQVDNCASNPCLNSGTCIDKVGGYECKCKSNTRGSHCQIKDDE
ISKCLNSCGDHYYGGKCWHNGEQKISVGWGLGEPICNTLQTCFNATKGQF
DDHEYIPAQLKPIQMQDTDDLVFITDRDASLYDHHFIPHILPMEASSRDA
FEKCNTTNALPLTKNISISKLNVNDKLLHPGIQYFIANMNHLYRCDFGLR
LNVTVKDKACTDPKDLTPNQFCNGHGKCYTDFTQKLYSCLCCEGYAGKYC
QHEDPCVAKPCSNNGQCKLIDIGSGMLNHECECQPGYHGKQCEKKINHCQ
SYPCQNDGACYPELGDFRCQCKEGFSGKQCEINNDECASSPCKNGGKCQD
GLNNFKCVCEPGFKGTLCEINIDDCEMQPCINSTCLDLVNNYTCACSPGQ
SGRNCEHVLDECSTYPCKNGKCVNEEGGPTCSCGIGYTGQLCELKLDLCR
HSQYCITKHAISCVDRGDNVTCTCADGWAGSNCGVNIDECEGNKCVNGGQ
CVDEVSGYVCKCKNGFTGLYCEVPPARVVPDIEIDFMADDCHKFMNPQGV
RYLEVNIISILQSSCDCPLTSQSIEPDTSKVICKDKMAGTFQTNLIFDNG
YQYRKDIICKMQRKIKEEKTPTIYHQTYIVNIKDEEGLCKEDNVVAEASE
SASSKTGVIVGVLVTLAIIVIALVCVVYKIKNSRNTKVGITHKFLKKTSF
DNAAYIKEDLSKDDSLDETSFMSRDDTLPESVSECPRWADSYDRARKIAG
RNRSNVPVGRFFDIHNPGGGTSKI Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005509 | calcium ion binding |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| molecular_function |
GO:0005509 |
calcium ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | PRINTS | PR00010 | EGFBLOOD | coord: 453..463
score: 42.03
coord: 445..452
score: 51.76
coord: 433..444
score: 52.35
coord: 501..507
score: 54.12 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 613..687
e-value: 0.43
score: 10.0 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 480..499
e-value: 2.6E-10
score: 39.8 |
| None | No IPR available | GENE3D | 2.60.40.1510 | | coord: 239..351
e-value: 9.8E-4
score: 18.9 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 111..140
e-value: 6.7E-13
score: 47.8
coord: 444..463
e-value: 5.8E-16
score: 57.6 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 520..554
e-value: 4.2E-10
score: 39.0
coord: 27..75
e-value: 1.2E-9
score: 37.6
coord: 76..110
e-value: 8.6E-6
score: 25.2
coord: 406..426
e-value: 4.0E-13
score: 48.7
coord: 352..388
e-value: 1.7E-9
score: 37.1 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 590..612
e-value: 1.9E-12
score: 46.8 |
| None | No IPR available | GENE3D | 2.10.25.10 | | coord: 557..589
e-value: 2.0E-6
score: 27.3 |
| None | No IPR available | GENE3D | 2.60.120.200 | | coord: 389..405
e-value: 0.082
score: 12.1
coord: 464..479
e-value: 0.055
score: 12.7
coord: 427..443
e-value: 0.013
score: 14.7
coord: 141..230
e-value: 0.089
score: 12.0
coord: 500..519
e-value: 0.28
score: 10.4 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 396..431
e-value: 3.47437E-5
score: 41.4682 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 435..469
e-value: 2.39521E-6
score: 44.5498 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 510..543
e-value: 3.70141E-4
score: 38.3866 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 110..145
e-value: 1.57347E-5
score: 42.2386 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 586..622
e-value: 1.26879E-6
score: 45.3202 |
| None | No IPR available | CDD | cd00054 | EGF_CA | coord: 471..506
e-value: 0.00121096
score: 36.8458 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 353..401 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 392..433 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 71..107 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 30..72 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 586..624 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 110..150 |
| None | No IPR available | SUPERFAMILY | 57196 | EGF/Laminin | coord: 434..476 |
| IPR000742 | EGF-like domain | SMART | SM00181 | egf_5 | coord: 398..431
e-value: 1.2E-4
score: 31.4
coord: 71..107
e-value: 0.071
score: 22.2
coord: 309..351
e-value: 36.0
score: 9.7
coord: 33..66
e-value: 0.0021
score: 27.3
coord: 112..145
e-value: 5.2E-4
score: 29.3
coord: 355..393
e-value: 1.9E-5
score: 34.1
coord: 589..622
e-value: 1.0E-6
score: 38.3
coord: 548..584
e-value: 110.0
score: 3.9
coord: 511..543
e-value: 7.0E-5
score: 32.2
coord: 436..469
e-value: 4.0E-7
score: 39.7
coord: 474..506
e-value: 9.8E-4
score: 28.4 |
| IPR000742 | EGF-like domain | PFAM | PF00008 | EGF | coord: 590..619
e-value: 1.4E-5
score: 25.2
coord: 437..465
e-value: 1.5E-6
score: 28.3
coord: 113..142
e-value: 1.1E-6
score: 28.7
coord: 399..428
e-value: 1.1E-6
score: 28.7
coord: 512..539
e-value: 4.1E-5
score: 23.7
coord: 356..390
e-value: 6.4E-5
score: 23.1 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 545..584
score: 9.655 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 30..66
score: 17.431 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 433..469
score: 22.802 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 508..543
score: 15.908 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 352..393
score: 17.292 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 471..506
score: 17.246 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 313..351
score: 9.492 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 586..622
score: 22.83 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 68..107
score: 10.03 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 109..145
score: 19.242 |
| IPR000742 | EGF-like domain | PROSITE | PS50026 | EGF_3 | coord: 395..431
score: 18.939 |
| IPR001881 | EGF-like calcium-binding domain | SMART | SM00179 | egfca_6 | coord: 586..622
e-value: 3.0E-9
score: 46.7
coord: 30..66
e-value: 0.24
score: 6.8
coord: 509..543
e-value: 3.5E-4
score: 29.7
coord: 352..393
e-value: 0.16
score: 8.2
coord: 68..107
e-value: 0.35
score: 5.4
coord: 109..145
e-value: 2.9E-7
score: 40.1
coord: 433..469
e-value: 9.6E-9
score: 45.1
coord: 471..506
e-value: 1.2E-7
score: 41.4
coord: 395..431
e-value: 2.3E-6
score: 37.1 |
| IPR013032 | EGF-like, conserved site | PFAM | PF12661 | hEGF | coord: 480..499
e-value: 0.011
score: 16.2
coord: 80..101
e-value: 0.016
score: 15.8 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 381..392 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 381..392 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 494..505 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 339..350 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 531..542 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 95..106 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 54..65 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 457..468 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 95..106 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 572..583 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 531..542 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 133..144 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 572..583 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 419..430 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 610..621 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 457..468 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS00022 | EGF_1 | coord: 339..350 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 419..430 |
| IPR013032 | EGF-like, conserved site | PROSITE | PS01186 | EGF_2 | coord: 610..621 |
| IPR000152 | EGF-type aspartate/asparagine hydroxylation site | PROSITE | PS00010 | ASX_HYDROXYL | coord: 124..135 |
| IPR000152 | EGF-type aspartate/asparagine hydroxylation site | PROSITE | PS00010 | ASX_HYDROXYL | coord: 601..612 |
| IPR000152 | EGF-type aspartate/asparagine hydroxylation site | PROSITE | PS00010 | ASX_HYDROXYL | coord: 485..496 |
| IPR000152 | EGF-type aspartate/asparagine hydroxylation site | PROSITE | PS00010 | ASX_HYDROXYL | coord: 448..459 |
| IPR018097 | EGF-like calcium-binding, conserved site | PROSITE | PS01187 | EGF_CA | coord: 109..133 |
| IPR018097 | EGF-like calcium-binding, conserved site | PROSITE | PS01187 | EGF_CA | coord: 586..610 |
| IPR018097 | EGF-like calcium-binding, conserved site | PROSITE | PS01187 | EGF_CA | coord: 433..457 |
| IPR009030 | Growth factor receptor cysteine-rich domain | SUPERFAMILY | 57184 | Growth factor receptor domain | coord: 420..549 |
Blast
BLAST of TCONS_00002252-protein vs. Swiss-Prot (Human)
Match: DNER (Delta and Notch-like epidermal growth factor-related receptor OS=Homo sapiens GN=DNER PE=1 SV=1) HSP 1 Score: 258.84 bits (660), Expect = 1.405e-74 Identity = 190/617 (30.79%), Postives = 277/617 (44.89%), Query Frame = 0
Query: 26 TPLEDRGACISNPCLHNGMCT------------VTSNGFICTCVNSYIGVNCERRADDCPRDLSMKCVHGVCKLDMNGNPK---CICKEGFEGPICSLQVDNCASNPCLNSGTCIDKVGGYECKCKSNTRGSHCQIKDDEISKCLNSCGDHYYGGKCWH--NGEQKISVGWGLGEPICNTLQTCFNATKGQFDDHEYIPAQLKPIQMQDTDDLVFITDRDASLYDHHFIPHILPMEASSRDAFEKCNTTNALPLTKNISISKLNVNDKLLHPGIQYFIANMN-HLYRCDFGLRLNVTVKDKACTDPKDLTPNQFCNGHGKCYTDFTQKLYSCLCCEGYAGKYCQHEDPCVAKPCSNNGQCKLIDIGSGMLNHECECQPGYHGKQCEKKINHCQSYPCQNDGACYPELGDFRCQCKEGFSGKQCEINNDECASSPCKNGGKCQDGLNNFKCVCEPGFKGTLCEINIDDCEMQPCINSTCLDLVNNYTCACSPGQSGRNCEHVLDECSTYPCKNGK-CVNEEGGPTCSCGIGYTGQLCELKLDLCRHSQYCITKHAISCVDRGDNVTCTCADGWAGSNCGVNIDECEGNKCVNGGQCVDEVSGYVCKCKNGFTGLYCEV 623
PL G C + PC + G+CT G+ CTC G NC+ AD C S C HG C + + CIC EG+EGP C + P L + + + + + T+ + + + L + W G++ + + W E I + C NA+ +L ++ + D ASL IL + ++ F++C+ + +T + L + +++L G +FI +N + + LRL + VK C + + C+G GKC T ++ +SC C E Y G +C+ D C KPC NN C + N C C PGY G+ C+ KI++C PC+N C L F CQC EG+ G CE D CASSPC+N G C +F C C PGF G C ID C + PC + TC + +Y C C PG G CE +EC + PC N C + G C C Y G CEL D C + C+ + +C G N TC CA G+ G C ++I+EC+ N C +GG C+D+ +GY C C +G+ G CE+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC---ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQAL------PSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPT----------WQPKTGQKVVEMKWDQVEVIPDI--ACGNASSNSSAG-----GRLVSFEVPQNTSVKIRQDATASL--------ILLWKVTAT-GFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVS-CL--NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618 HSP 2 Score: 90.5077 bits (223), Expect = 1.324e-18 Identity = 56/150 (37.33%), Postives = 81/150 (54.00%), Query Frame = 0
Query: 324 GHGKCYTDFTQKLYSCLCCEGYAGKYCQHE-DPCVAKPCSNNGQCKLIDIGSGMLNHECECQPGYHGKQCEKKINHCQSYPCQNDGACYPELGDFRCQCKEGFSGKQCEINNDECASSPCKNGGKCQDGLNNFKCVCEPGFKGTLCEINI 472
HG C + T Y CLC GY G YC+ E + C++ PC N C+ D+ +G +EC C Y G CE + C + C N C + + C C GF+G++C+I+ +EC S+PC +GG C D N + C C G+ G CEI++
Sbjct: 478 AHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNECLSAPCLNAATCR--DLVNG---YECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
The following BLAST results are available for this feature:
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