TCONS_00004363-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00004363-protein
Unique Name	TCONS_00004363-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	451

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00004363-protein ID=TCONS_00004363-protein|Name=TCONS_00004363-protein|organism=Clytia hemisphaerica|type=polypeptide|length=451bp
MAIINSTILWTLYIGVWLSMVSLTNSAAYSIEQDLMEQVISNYIPTRPVQ
RNNETVHVKIQLEIVQITVSTKAQTLSVTGFFRLKWKNDLIHWNASHYDG
INTVNIDPHLMWFPEVVLHNSLSEERTWLTKSFKTKISVSSDGTCYWLSP
IDFLSSCSFSIKDFPFDTQHCKITFGPWTDDISKVYMEAIDYAVVTSQYT
ENAEWDLREASHEIVTSYYKCCPIPFRDLVIRLTLTRKPLFYMVNSIVPC
ICLIVLLILGHRLPPQCGERITLTIMICLTCIVMMEYTNSKILPQTSEVS
SFSKIFLTITIVASFSILETCYVLSLHHRSEGMLRWMPSWLTRLILKSSS
SNESPESHDTHASNSSETPQVIDQGRIAPQMSSNEDEEGTSKETLNLIYE
EIKNYNKEVNEDDFSHIPEQDAKKIAKFLDNVFIVAALISVMVALLVEIK
L

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_002439	XLOC_002439	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00004363	TCONS_00004363	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 448..451
None	No IPR available	GENE3D	1.20.58.390		coord: 245..449 e-value: 3.3E-27 score: 94.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 351..391
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 77..93 score: 17.89 coord: 157..171 score: 45.07 coord: 233..245 score: 37.42 coord: 110..121 score: 34.69
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 33..239 e-value: 8.7E-41 score: 139.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 20..244 e-value: 4.8E-50 score: 169.5
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 32..239
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 247..347 e-value: 5.8E-13 score: 49.4
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 239..443
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 157..171

Blast

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BLAST of TCONS_00004363-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 185.267 bits (469), Expect = 5.221e-53
Identity = 109/337 (32.34%), Postives = 180/337 (53.41%), Query Frame = 0

Query:   15 GVWLSMVS--LTNSAAYSIEQDLMEQVISNYIP-TRPVQRNNETVHVKIQLEIVQIT-VSTKAQTLSVTGFFRLKWKNDLIHWNASHYDGINTVNIDPHLMWFPEVVLHNSLSEERTWLTKSFKTKISVSSDGTCYWLSPIDFLSSCSFSIKDFPFDTQHCKITFGPWTDDISKVYMEAIDYAVVTSQYTENAEWDLREASHEIVTSYYKCCPIPFRDLVIRLTLTRKPLFYMVNSIVPCICLIVLLILGHRLPPQCGERITLTIMICLTCIVMMEYTNSKILPQTSE-VSSFSKIFLTITIVASFSILETCYVLSLHHRSEGMLRWMPSWLTRLIL 346
            GVWL++ +  L  S     ++ L ++++ NY P  RPV  +++ + V   L ++QI  V  K Q L+   + ++ W +  + WN S Y G+ TV      +W P+++L+NS  E       +F T + V+S G C +L P  F SSC   ++ FPFD QHCK+ FG W+     + ++  +  +  S Y  N EWDL     +    +Y+CC  P+ D+   +T+ R+ L+Y +N ++PC+ +  L +L   LP   GE+I+L I + L+  V M    ++I+P TS+ V   ++ F +  I+   S++ T  VL  HH      + MP W TR+IL
Sbjct:    7 GVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADER---FDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI--SGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLV-AEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGK-MPKW-TRVIL 335

The following BLAST results are available for this feature:

BLAST of TCONS_00004363-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00004363-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	5.221e-53	32.34	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00004363-protein (polypeptide) - C. hemisphaerica