TCONS_00052075-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00052075-protein
Unique NameTCONS_00052075-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length873

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00052075-protein ID=TCONS_00052075-protein|Name=TCONS_00052075-protein|organism=Clytia hemisphaerica|type=polypeptide|length=873bp
MRKCLAIILSGLIVLQNLLTVSSQSCNGESIQDLNATYIIGGLFPVHYRV
SETNQYIFNILSIVWVEAFLFALREINNIKDLLPGIKLGYDIKDTCNDGM
VAENHVLDLMTDRKFFQSSHQAFSNWYAPCECYDEQQSKMIGVVGGASST
ISSIAAHTLIAGNIPQISYASTSPLLSNSRTYPNFLRTIPSDLQQVSVVT
ELLQVMDWTYVSLLATDDDFGRLALNLVQENFKQNNICIALEYLYSSNLS
TGDLAEITRGLSKYQNRTKVVIIWATEFWNVEKIITNTSNDGLDDMLWIV
LSESWITKFQSNLPRRQHVIMLQLEDFQVESFVDHMNKLSFGSDLGNIWM
PQYWTSLGICPENEGERTKYCYDHWIPEGRVLGRKYSENVIASVYAFAYG
LHKTLDCNEKNCEQKPFLDYEALKLNILANTFILPSTNLSIEFQPNGDVN
ANSYQIRMFSFEKNVLLGSWSKTNNIQINQTEFWLHYDNENQSSTNIPAT
CSTPCKPGFYKRQESQTCCWSCIQCPYDEVSLGIDSLGCQKCGPLEIANK
QQDKCVPLPNKEFSLTAQTGLIIGIISLVGFMFTLFTILVYMILWETPGV
KSTNRELSLIQLVCILLLFCFPVLNLYTHKSLCIARQVIFGSLHSLILVL
VLLKTYRLFKLFQPQFFKKHTRMFLTISAQIFFAFFLLLIETTVLAMWYT
VHQPSMILYSSKGEGGYIYHCGDHESYVLYAIIIYVILLSLASGFIAFRA
RSLPANFNEAQYIWLAMFTYCIIWCAFFPLHLSSNKLYKSTILLSMNLAS
TFSLIAILFGNKIRMLVCLPHLNNRLHFTGLAANAYIRTFSLRQSESPGK
NKKKKMRDKKRVISFSFELENNV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032982XLOC_032982Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00052075TCONS_00052075Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000337GPCR_3
IPR011500GPCR_3_9-Cys_dom
IPR017978GPCR_3_C
IPR001828ANF_lig-bd_rcpt
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 758..779
score: 51.14
coord: 680..703
score: 17.97
coord: 143..169
score: 41.44
coord: 641..662
score: 28.55
coord: 77..96
score: 55.62
coord: 195..211
score: 27.21
coord: 597..619
score: 46.2
coord: 735..758
score: 42.84
coord: 176..195
score: 49.06
coord: 211..228
score: 28.3
coord: 35..47
score: 50.72
coord: 62..77
score: 43.95
NoneNo IPR availableGENE3D3.40.50.2300coord: 36..450
e-value: 1.8E-55
score: 187.9
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..26
score: 6.0
IPR011500GPCR, family 3, nine cysteines domainPFAMPF07562NCD3Gcoord: 500..543
e-value: 1.5E-10
score: 40.8
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 582..814
e-value: 5.4E-36
score: 124.5
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 569..823
score: 35.234
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 65..456
e-value: 6.5E-51
score: 173.4
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 35..478

Blast
BLAST of TCONS_00052075-protein vs. Swiss-Prot (Human)
Match: GRM3 (Metabotropic glutamate receptor 3 OS=Homo sapiens GN=GRM3 PE=1 SV=2)

HSP 1 Score: 278.1 bits (710), Expect = 1.970e-80
Identity = 234/849 (27.56%), Postives = 393/849 (46.29%), Query Frame = 0
Query:   39 IIGGLFPVHYRVSETNQ--YIFNILSIVWVEAFLFALREINNIKDLLPGIKLGYDIKDTCNDGMVAENHVLDLMTDRKFFQSSHQAFSNWYAPCECYDEQQS---KMIGVVGGASSTISSIAAHTLIAGNIPQISYASTSPLLSNSRTYPNFLRTIPSDLQQVSVVTELLQVMDWTYVSLLATDDDFGRLALNLVQENFKQNNICIA-LEYLYSSNLSTGDLAEITRGLSKYQNRTKVVIIWATEFWNVEKIITNTSNDGLDDMLWIVLSESWITKFQSNLPRRQHV----IMLQLEDFQVESFVDHMNKLSFGSDLGNIWMPQYWTSLGICP-ENEGERTKYCYDHWIPEGRVLGRKYSEN-----VIASVYAFAYGLHK---TLDCN-EKNCEQKPFLDYEALKLNILANTFILPSTNLSIEFQPNGDVNA---------NSYQIRMFSFE------KNVLLGSWSKTNNIQINQTEFWLHYDNENQSSTNIPAT-CSTPCKPGFYKR-QESQTCCWSCIQC-PYDEVSLGIDSLGCQKCGPLEIANKQQDKCVPLPNKEFSLTAQTGLIIGIISLVGFMFTLFTILVYMILWETPGVKSTNRELSLIQLVCILLLFCFPVLNLYTHKS-LCIARQVIFGSLHSLILVLVLLKTYRLFKLFQPQFFKKHTRMFLTISAQIFFAFFLLLIETTVLAMWYTVHQPSMILYS-SKGEGGYIYHCGDHESYVLYAIIIYVILLSLASGFIAFRARSLPANFNEAQYIWLAMFTYCIIWCAFFPLHLSSNKLYK---STILLSMNLASTFSLIAILFGNKIRMLVCLPHLN---NRLHFTGLAANAYIRTFS 841
            ++GGLFP++ + + T +   I     I  +EA LFA+ EIN    LLPG+KLG  I DTC+    A    L+ +  R       +A   +  P   Y  Q++    + GV+GG+ S++S   A+ L    IPQISYASTS  LS+   Y  F RT+P D  Q   + E+L+  +WTYVS +A++ D+G   +   ++  +  NICIA  E +  SN+     + I   L K   R  V+ + + +     + +   ++       W+  S+ W  + +S +   +HV    I L+L    V  F  +   L+  ++  N W   +W     C  +N+    + C  H      +    Y +      V+ +VYA A+ LHK   TL  N  K C+    LD + L  + L         N +  F PN D ++            +  +F+F+        + +G W++T ++ +N     +H+     S  ++P + CS PC P   K  Q    CCW CI C PY+ ++   D   C  CG  +        C  LP           +    I+ +GFM T   + V++    TP VK++ REL  I L  + L +C     +      +C  R++  GS  ++    +L KT  + ++F           F++ S+Q+F    L+L++  ++++W  +  P    Y+ ++     I  C   +S +L ++   VIL+ L + + AF+ R  P NFNEA++I   M+T CIIW AF P+   ++  Y+   +T+ +S++L S F ++  LF  K+ +++  P  N   +RLH    + +    T+S
Sbjct:   40 VLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFV--RASLTKVDEA--EYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDD----SRELIAAASRANASFTWVA-SDGWGAQ-ESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLA----IDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLK------INFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNS----IHW-----SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLA---DEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVY-AFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSL-SGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTGTTYS 854          
The following BLAST results are available for this feature:
BLAST of TCONS_00052075-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GRM31.970e-8027.56Metabotropic glutamate receptor 3 OS=Homo sapiens ... [more]
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