TCONS_00059201-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00059201-protein
Unique NameTCONS_00059201-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1360

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00059201-protein ID=TCONS_00059201-protein|Name=TCONS_00059201-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1360bp
MDCTSHCKLKAHGSYLTSIITSETDGEVFKKASNEKCNNSSKVLDHLGRN
VFHVATSCGNIDVLEYLIEEQNVSKSNLQSKDKESGWTPLHRALYYGNIH
CAVYLHKVLKEWKPFDSEGLSPLDLVTQDSPRIKKKKKRMTKLGIVVVAY
EAELQSELTIQIDDIIEMADRPSGITGWAIGKNRETGHEGFYPQHFVEEI
KQKVEKETKAWYTPQNTVHLWGNNVNFTLGLGDSKSRNTAELNETLFHSQ
QSVKDVVVTKFHTVYLTNEGNVFTCGHGPGGRLGHGQEQTLLYPEPIKTL
SCYHCTIIAASNHHTVVVTELGDVYTFGLNDFHQLGLSPAPISASTPQLV
YNKNFKGKQIMGAAAGRFHTVIHSDKEVYVFGYNGGQMGLLKSEEIVITP
KQVSRLLRNKTEVKMVAASDGATLCLYEDGEVYILQDFVCRKIKDIGSFL
PGTKIRMTGGELQLKRSDFEKPEPLQIAILQSTGVVFVWRSSTRQFRECY
WQGCKLPVYSNVVDIALGKHLMITTDTGQVYFGHFSNRTQPGQGAKPEDT
HSSATPRSSRNKVEVVESGQKLSLTELNDRTKKARFDHEEIMLERVPLVY
RSVACFCDPKSRTYAVIQFDPITEMKRRPEVSPSTLESDLRRLVEKADLY
DDLHDLVIESKNKTCFPAHRFVLQLRLGLPIYTSLLFSTCDNKGEGKKRI
ILKDKDGDQVKKWLQRVYSEDRGNMGTIAKMEDEATSGKLENDEDLEVEE
LPKEMISLSKLDLADPSDDYFQYPKNEGDIVQGGPGSGNIGNAASPTSNS
EKSAYSVFKEKQERESKEDKKKPKKKKKEPSKLNSFEGWRKYPECSDVTI
ESVDQKIFKCHKCILTARSEYFQNMLNFSWMECSSSSTSSSIKIPVPSNI
LDVVINFLYTGNIKHLAASNDVTFIGEVLVCADQLLILRLKELCEVCLSE
KVTLKNVVDIFQFSCMYNAEQLRVFTSDYISMNMPYFLDAKLLENVPNED
LEILSDEYKFLVADMDERVITPSFHHREVDRKVEELQNAITSDLNKIKAR
RRRNSSRSDVEQQSQIVEKQNQNVEKNSVEDMRIDEESKQVVFVDDSQTS
SMDTTTRQIKVDEKPSSWGKVNQSKVPNTNVSPSVFESKELLHKKQNTPS
PFKKKSQRERRRQASQSKSESEEASVINTINEEKKENVCPWGQSKGGTPS
PPVKTFIDLLSEESSPKLGEEVEKNNTQRKQHIKAPPKFKKKLLLGDKII
AKEKQGPAKSAWGALPPVTKTTINLHDNTQPQNEHKEVEVFTNVIQDQED
EKEQIIKDSKKPLTIIQLEERAMTELKDFYEKNALKGEKISVQRIRKIDN
VIPFWEKVLH
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037280XLOC_037280Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00059201TCONS_00059201Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR002110Ankyrin_rpt
IPR000210BTB/POZ_dom
IPR020683Ankyrin_rpt-contain_dom
IPR000408Reg_chr_condens
IPR011333SKP1/BTB/POZ
IPR009091RCC1/BLIP-II
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1057..1077
NoneNo IPR availableGENE3D2.130.10.30coord: 203..581
e-value: 1.8E-55
score: 187.8
NoneNo IPR availableGENE3D3.30.710.10coord: 833..991
e-value: 1.2E-28
score: 99.3
NoneNo IPR availableGENE3D2.30.30.40coord: 139..202
e-value: 9.1E-10
score: 37.4
NoneNo IPR availableGENE3D3.30.710.10coord: 620..752
e-value: 0.001
score: 18.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 534..562
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 772..833
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1046..1205
NoneNo IPR availableCDDcd00204ANKcoord: 45..128
e-value: 6.20105E-11
score: 60.475
NoneNo IPR availableCDDcd14821SPOP_C_likecoord: 952..985
e-value: 1.60306E-4
score: 40.2272
IPR001452SH3 domainSMARTSM00326SH3_2coord: 142..201
e-value: 2.4E-5
score: 33.8
IPR001452SH3 domainPROSITEPS50002SH3coord: 139..202
score: 10.813
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 144..207
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 85..116
e-value: 5.1
score: 16.1
coord: 47..75
e-value: 0.81
score: 18.7
IPR000210BTB/POZ domainSMARTSM00225BTB_4coord: 846..952
e-value: 3.9E-13
score: 59.7
IPR000210BTB/POZ domainPFAMPF00651BTBcoord: 840..950
e-value: 9.2E-14
score: 51.5
IPR000210BTB/POZ domainPROSITEPS50097BTBcoord: 846..917
score: 14.563
IPR020683Ankyrin repeat-containing domainPFAMPF12796Ank_2coord: 27..105
e-value: 3.8E-7
score: 30.5
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 13..138
e-value: 2.8E-12
score: 45.9
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 47..128
score: 11.108
IPR020683Ankyrin repeat-containing domainSUPERFAMILY48403Ankyrin repeatcoord: 42..126
IPR000408Regulator of chromosome condensation, RCC1PFAMPF00415RCC1coord: 269..318
e-value: 2.6E-6
score: 27.8
coord: 322..371
e-value: 7.6E-8
score: 32.8
IPR000408Regulator of chromosome condensation, RCC1PROSITEPS50012RCC1_3coord: 270..321
score: 11.449
IPR000408Regulator of chromosome condensation, RCC1PROSITEPS50012RCC1_3coord: 322..376
score: 12.795
IPR011333SKP1/BTB/POZ domainSUPERFAMILY54695POZ domaincoord: 831..950
IPR009091Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IISUPERFAMILY50985RCC1/BLIP-IIcoord: 503..544
coord: 210..441

Blast
BLAST of TCONS_00059201-protein vs. Swiss-Prot (Human)
Match: IBTK (Inhibitor of Bruton tyrosine kinase OS=Homo sapiens GN=IBTK PE=1 SV=3)

HSP 1 Score: 363.229 bits (931), Expect = 1.232e-104
Identity = 228/687 (33.19%), Postives = 346/687 (50.36%), Query Frame = 0
Query:    2 DCTSHCKLKAHGSYLTSIITSETDGEVFKKASNEKCNNSSKVLDHLGRNVFHVATSCGNIDVLEYLIEEQNVSKSNLQSKDKESGWTPLHRALYYGNIHCAVYLHKVLKEWKPFDSEGLSPLDLVTQDSPRIKKKKKRMTKLGIVVVAYEAELQSELTIQIDDIIEMADRPSGITGWAIGKNRETGHEGFYPQHFVEEIKQKVEKETKAWYTPQNTVHLWGNNVNFTLGLGDSKSRNTAELNETLFHSQQSVKDVVVTKFHTVYLTNEGNVFTCGHGPGGRLGHGQEQTLLYPEPIKTLSCYHCTIIAASNHHTVVVTELGDVYTFGLNDFHQLGLSPAPISASTPQLVYNKNFKGKQIMGAAAGRFHTVIHSDKEVYVFGYNGGQMGLL---KSEEIVITPKQVSRLLRNKTEVKMVAASDGATLCLYEDGEVYILQDFVCRKIKDIGSFLPGTKIRMTGGELQLKRSDFEKPEPLQ--------IAILQSTGVVFVWRSSTRQFRECYWQGCKLPVYSNVVDIALGKH-LMITTDTGQVYFGHFSNRTQPGQGAKPEDTHSSATPRSSRNKVEVVESGQKLSLTELNDRTKKARFDHEEIMLERVPLVYRSVACFCDPKSRTYAVIQFDPITEMKRRPEVSPSTLESDLRRLVEKADLYDDLHDLVIESKNKTCFPAHRFVLQLR 676
            DCTS C+   H   + S++T  ++ ++ K   +  C N++ + D  GRN  H+ +SCG   VL++LI++      +L  KDKESGWT LHR+++YG+I C   L K           G+S   L  QD       K+ ++ L +V                     M DRP+ +    + KN                             T    V+ WG+N NFTLG G   S++  EL +    S   +K VV+ KFH+V+L+ +G V+TCGHGPGGRLGHG EQT L P  ++ L+ ++C+ +AA+  HTVV+TE G VYTFGLN FHQLG+ P P S + P+ +  K  KG+ I+G AAGRFHTV+ + + VY  G NGGQ+G L     E+ V  P+QVS L      + +VAASDGAT+C+   G++Y+L D+ C+K+      L   K+ ++GG ++ K      PE L+        I  +   G VF WRS     ++C W     P    + DIAL ++ ++  T  G+ + G +                     R S  K E++ +    S          + +  E I LE++   +R+V+   DP    +A++Q DP T +   P VS S+   +  +L+ +AD  D +HD+  +  N+  FPAH+++L + 
Sbjct:    7 DCTSKCRSLKHALDVLSVVTKGSENQI-KAFLSSHCYNAATIKDVFGRNALHLVSSCGKKGVLDWLIQK----GVDLLVKDKESGWTALHRSIFYGHIDCVWSLLK----------HGVS---LYIQD-------KEGLSALDLV---------------------MKDRPTHV----VFKN-----------------------------TDPTDVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGATVCVTTRGDIYLLADYQCKKMA--SKQLNLKKVLVSGGHMEYKVD----PEHLKENGGQKICILAMDGAGRVFCWRSVNSSLKQCRW---AYPRQVFISDIALNRNEILFVTQDGEGFRGRWFEEK-----------------RKSSEKKEILSNLHNSSSDVSYVSDINSVY--ERIRLEKLTFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPAVSSSSFFEEFGKLLREADEMDSIHDVTFQVGNRL-FPAHKYILAVH 585          

HSP 2 Score: 167.548 bits (423), Expect = 1.073e-41
Identity = 83/176 (47.16%), Postives = 124/176 (70.45%), Query Frame = 0
Query:  847 DVTIESVDQKIFKCHKCILTARSEYFQNMLNFSWMECSSSSTSSSIKIPVPSNILDVVINFLYTGNIKHLAASNDVTFIGEVLVCADQLLILRLKELCEVCLSEKVTLKNVVDIFQFSCMYNAEQLRVFTSDYISMNMPYFLDAKLLENVPNEDLEILSDEYKFLVADMDERVITP 1022
            DVT++SVD K F CHKC+L AR EYF +ML+ SW+E SS +   ++++P+ S+IL V++++LYT     +  S +V FI  VLV ADQLLI RLKE+CEV L+EK+TLKN   + +F+ MY+A+QL++    +I +NM   L+A+ L+ + +  L+ LS+ Y+ ++  MD RVITP
Sbjct:  769 DVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCA---ALEMPIHSDILKVILDYLYTDEAVVIKESQNVDFICSVLVVADQLLITRLKEICEVALTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFIGLNMAALLEARSLDVLSDGVLKDLSEFYRKMIPAMDRRVITP 941          
The following BLAST results are available for this feature:
BLAST of TCONS_00059201-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IBTK1.232e-10433.19Inhibitor of Bruton tyrosine kinase OS=Homo sapien... [more]
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