TCONS_00068842-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00068842-protein
Unique NameTCONS_00068842-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length755

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00068842-protein ID=TCONS_00068842-protein|Name=TCONS_00068842-protein|organism=Clytia hemisphaerica|type=polypeptide|length=755bp
MCCGLSSHLSYGRSSSCTEFIEYPCWLLRKCTNQLCHHQERCVERXGSAQ
TNSATIKNDVLRGKLNLVYVTPEYLCASQNFLKELSEKTNLVCVAVDEAH
CVSQWGYDFRTSYQQLSFIKKVVPDVPLLALTATATPRVRKDICTNLNLY
RPLEKCTSFDRENLYLEVQRKSSIYMDLKPLLSKDRNAQMRFTGSTIIYC
PTKKKTSEVMDVLLSFGVKCAIYHAGLALTTRKECYRKFMSDEIDCIIAT
VAFGMGIDKPDIRTVIHYGAPKDIESYYQEIGRAGRDGNPSNCITFFNAA
DFGLSRHFISDIRDETFKTYKVEMLAKLEKFLTTTGCRRKTILKHFENVG
SSCGGHKDCCDNCRKKELNKKSKAVGSKTPVKDKEEEDEYDVGKECVKLL
DAVKATGNGRFGITVPILLLKASTSQKISHLKYTDMYGAGKDKTERYWKA
LGREILIKGFLEEQPIANSFGSTVKVSAKGQKWLTQQSKKAEPKLMLSNP
SLDLVTEINGRLAPDRASPYTAAKLTERILRKQPRVAPWKKHVALMSSIL
QGAQRCGTPFDGVSLQRSEGPVERLTETQSASYVLHKDGQTLDEIAKRRA
LVHDTIYGHICSALLAGFPVHLKLVDLTFDDVALVVKTMSSENISYNISQ
LRPIKDKLPASIGFGKLKFVLAMLEVHFGVEGEDPPQQPNQEALQNIIDS
AMQASQTVNSQNSTSSNNNNGAKRKVPGWLEAKMGSSQKASYKRSSSKKQ
RSGFL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042915XLOC_042915Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00068842TCONS_00068842Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001650Helicase_C
IPR018982RQC_domain
IPR004589DNA_helicase_ATP-dep_RecQ
IPR029491Helicase_HTH
IPR032284RecQ_Zn-bd
IPR011991WHTH_DNA-bd_dom
IPR014001Helicase_ATP-bd
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0043140ATP-dependent 3'-5' DNA helicase activity
GO:0008026ATP-dependent helicase activity
Vocabulary: Biological Process
TermDefinition
GO:0006260DNA replication
GO:0006281DNA repair
GO:0006310DNA recombination
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006310 DNA recombination
biological_process GO:0006281 DNA repair
biological_process GO:0006260 DNA replication
molecular_function GO:0043140 ATP-dependent 3'-5' DNA helicase activity
molecular_function GO:0008026 ATP-dependent helicase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001650Helicase, C-terminalSMARTSM00490helicmild6coord: 207..288
e-value: 7.5E-26
score: 101.9
IPR001650Helicase, C-terminalPFAMPF00271Helicase_Ccoord: 192..287
e-value: 1.4E-19
score: 70.4
IPR001650Helicase, C-terminalPROSITEPS51194HELICASE_CTERcoord: 177..333
score: 19.581
IPR018982RQC domainSMARTSM00956RQC_2coord: 391..494
e-value: 1.6E-10
score: 50.9
IPR018982RQC domainPFAMPF09382RQCcoord: 388..488
e-value: 4.6E-15
score: 55.3
IPR004589DNA helicase, ATP-dependent, RecQ typeTIGRFAMTIGR00614TIGR00614coord: 47..443
e-value: 3.4E-128
score: 426.3
NoneNo IPR availableGENE3D3.40.50.300coord: 27..159
e-value: 9.5E-12
score: 44.1
NoneNo IPR availableGENE3D3.40.50.300coord: 161..367
e-value: 9.7E-45
score: 151.9
NoneNo IPR availableCDDcd00079HELICccoord: 194..296
e-value: 1.44643E-30
score: 116.568
NoneNo IPR availableCDDcd00046DEXDccoord: 52..134
e-value: 8.24874E-7
score: 46.9468
IPR029491Helicase Helix-turn-helix domainPFAMPF14493HTH_40coord: 578..671
e-value: 1.3E-13
score: 51.1
IPR032284ATP-dependent DNA helicase RecQ, zinc-binding domainPFAMPF16124RecQ_Zn_bindcoord: 300..364
e-value: 5.3E-8
score: 33.3
IPR011991Winged helix-turn-helix DNA-binding domainGENE3D1.10.10.10coord: 381..503
e-value: 3.6E-20
score: 71.5
IPR011991Winged helix-turn-helix DNA-binding domainSUPERFAMILY46785"Winged helix" DNA-binding domaincoord: 387..489
IPR014001Helicase superfamily 1/2, ATP-binding domainPROSITEPS51192HELICASE_ATP_BIND_1coord: 58..153
score: 13.873
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 57..303

Blast
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BLAST of TCONS_00068842-protein vs. Swiss-Prot (Human)
Match: WRN (Werner syndrome ATP-dependent helicase OS=Homo sapiens GN=WRN PE=1 SV=2)

HSP 1 Score: 417.157 bits (1071), Expect = 5.384e-129
Identity = 208/463 (44.92%), Postives = 300/463 (64.79%), Query Frame = 0 
Query:   47 GSAQTNSATIKNDVLRGKLNLVYVTPEYLCASQNFLKELSEKTNLVCVAVDEAHCVSQWGYDFRTSYQQLSFIKKVVPDVPLLALTATATPRVRKDICTNLNLYRPLEKCTSFDRENLYLEVQRKS-SIYMDLKPLLSKDRNAQMRFTGSTIIYCPTKKKTSEVMDVLLSFGVKCAIYHAGLALTTRKECYRKFMSDEIDCIIATVAFGMGIDKPDIRTVIHYGAPKDIESYYQEIGRAGRDGNPSNCITFFNAADFGLSRHFISDIRDETFKTYKVEMLAKLEKFLTTTGCRRKTILKHFEN---VGSSCG--GHKDCCDNCRKKELNKKSKAVGSKTPVKDKEEEDEYDVGKECVKLLDAVKATGNGRFGITVPILLLKASTSQKIS-HLKYTDMYGAGKDKTERYWKALGREILIKGFLEEQPIANSFGSTVKVSAKGQKWLTQQSKKAEPKLMLSNPSL 502
            GSAQ  S  +  D+  GK  +VYVTPEY   +   L++L     +  +AVDEAHC+S+WG+DFR S+++L  +K  +P VP++ALTATA+  +R+DI   LNL  P   CT FDR NLYLEV+RK+ +I  DL+P L K  ++   F G TIIYCP++K T +V   L    + C  YHAG++ +TRK+ + +F+ DEI C+IAT+AFGMGI+K DIR VIHYGAPKD+ESYYQEIGRAGRDG  S+C   +  AD  L+RH +++IR+E F+ YK++M+AK+EK+L ++ CRR+ IL HFE+     +S G  G + CCDNCR +  +  S          D  E+  +D G +  KLL AV   G  +FGI +PIL L+ S SQ+++   +   ++G GKD+TE +WKA  R+++ +GFL E    N F     ++ KG+ WL + + +++  ++ +N  L
Sbjct:  620 GSAQ--SENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVK-TSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYS---------MDDSEDTSWDFGPQAFKLLSAVDILGE-KFGIGLPILFLRGSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLVEVSRYNKFMKICALTKKGRNWLHKANTESQSLILQANEEL 1069
The following BLAST results are available for this feature:
BLAST of TCONS_00068842-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
WRN5.384e-12944.92Werner syndrome ATP-dependent helicase OS=Homo sap... [more]
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