TCONS_00069234-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069234-protein
Unique NameTCONS_00069234-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length646

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069234-protein ID=TCONS_00069234-protein|Name=TCONS_00069234-protein|organism=Clytia hemisphaerica|type=polypeptide|length=646bp
MKNNLIISLLYIFATLRRCQGQCSGNKFPAADNGVCLPCGLNSNSNGTDC
NCNPSYSRFHYQQFDYSESCYRIPSQPRNLELVNITGESVFYKWDPPLIV
DTTLESRYLILFSKCEGTSCQAIYSRELDNSQTTWSIGDLKPDSVYLMIV
CASNDMFMNNTFYRNAHQHESCYKDSRRTTDGVPGGFNRLLIRANAHQDE
KNIHIFQIPAPAHLGGASIKEWSAHIDCDNSKSTTIKETYNTTTFQNNQL
FFITTEKICAVTTQCEFYASNKYGIGPKVPKIFQFNDDCDEEDNDTLVTV
VVVVIVVVVIVIVGILVYLWRWRKQQARMEQLWLLQLERANNVSNNMVMP
FRAHNLYVDAMEVEQTLEKEFSTKQVDLTDDDCNYLEDNSFDFEYNRQQL
EFKYKLGEGQFGCVYKAEAIDIAGKPGKSTVAVKVLKANPEEKDKQEFID
ELDLLKLIKPHPNVVRLLGCCTKRGQQLAMIFEVMPSGDLQNLLRKTKKR
ADETNQPIDEMIDIGEFLRFAIDIANGMDHLSFHKIVHRDLAARNVLVGN
NRVCKISDMGLARPLNDDGVFHREKEAKLPIKWMSPESIKYGRSSIKSDV
WSFGIVLWEIFTLGASPYPGFKSKEVPALLCHERYRMNKPEHCSEK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043148XLOC_043148Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069234TCONS_00069234Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR020963ArabinofuranosylTrfase_AftA_N
IPR013783Ig-like_fold
IPR003961FN3_dom
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0016757transferase activity, transferring glycosyl groups
GO:0005515protein binding
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0044038cell wall macromolecule biosynthetic process
Vocabulary: Cellular Component
TermDefinition
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0044038 cell wall macromolecule biosynthetic process
biological_process GO:0006468 protein phosphorylation
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0005886 plasma membrane
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0016757 transferase activity, transferring glycosyl groups
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 482..495
score: 40.45
coord: 579..589
score: 59.29
coord: 530..548
score: 59.0
coord: 598..620
score: 68.47
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 400..645
e-value: 1.5E-76
score: 257.0
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 400..646
e-value: 2.0E-89
score: 313.1
IPR020963Arabinofuranosyltransferase AftA, N-terminalPFAMPF12250AftA_Ncoord: 306..388
e-value: 1.4E-5
score: 24.0
NoneNo IPR availableGENE3D1.10.510.10coord: 472..646
e-value: 2.0E-42
score: 144.9
NoneNo IPR availableGENE3D3.30.200.20coord: 376..471
e-value: 2.2E-19
score: 68.9
NoneNo IPR availableGENE3D1.20.5.100coord: 290..328
e-value: 0.0015
score: 17.6
NoneNo IPR availableCDDcd00192PTKccoord: 405..646
e-value: 2.34762E-109
score: 331.811
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 72..158
e-value: 1.7E-9
score: 37.3
IPR003961Fibronectin type IIIPFAMPF00041fn3coord: 75..155
e-value: 5.6E-6
score: 26.5
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 76..175
score: 10.367
IPR003961Fibronectin type IIICDDcd00063FN3coord: 74..155
e-value: 2.5338E-6
score: 44.7947
IPR003961Fibronectin type IIISUPERFAMILY49265Fibronectin type IIIcoord: 72..157
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 536..548
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 406..434
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 400..646
score: 36.909
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 389..645

Blast
BLAST of TCONS_00069234-protein vs. Swiss-Prot (Human)
Match: FGFR2 (Fibroblast growth factor receptor 2 OS=Homo sapiens GN=FGFR2 PE=1 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 1.112e-54
Identity = 108/258 (41.86%), Postives = 161/258 (62.40%), Query Frame = 0
Query:  393 FEYNRQQLEFKYKLGEGQFGCVYKAEAIDI-AGKPGKS-TVAVKVLKANPEEKDKQEFIDELDLLKLIKPHPNVVRLLGCCTKRGQQLAMIFEVMPSGDLQNLLRKTKKRADE----TNQPIDEMIDIGEFLRFAIDIANGMDHLSFHKIVHRDLAARNVLVGNNRVCKISDMGLARPLNDDGVFHREKEAKLPIKWMSPESIKYGRSSIKSDVWSFGIVLWEIFTLGASPYPGFKSKEVPALLCHERYRMNKPEHCS 644
            +E+ R +L     LGEG FG V  AEA+ I   KP ++ TVAVK+LK +  EKD  + + E++++K+I  H N++ LLG CT+ G  L +I E    G+L+  LR  +    E     N+  +E +   + +     +A GM++L+  K +HRDLAARNVLV  N V KI+D GLAR +N+   + +    +LP+KWM+PE++     + +SDVWSFG+++WEIFTLG SPYPG   +E+  LL  E +RM+KP +C+
Sbjct:  474 WEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGP-LYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLL-KEGHRMDKPANCT 729          
The following BLAST results are available for this feature:
BLAST of TCONS_00069234-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR21.112e-5441.86Fibroblast growth factor receptor 2 OS=Homo sapien... [more]
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