TCONS_00069540-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069540-protein
Unique NameTCONS_00069540-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1372

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069540-protein ID=TCONS_00069540-protein|Name=TCONS_00069540-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1372bp
MALQKRYQALEEQIKNPRNELYVEGLLDSITSIYHDCDYPSIRKEKNFEN
FLNRYGHLAKEIEKSRVNITDFNLIRVIGRGAFGEVQLVRHKDNKTVYAM
KSLSKFEMIKRSESAFFWEERDIMAHSNSDWIISLHYAFQDEKFLYMIMD
YMPGGDLVNLIETYDIPEGWAKFYLAELILALDAIHSMGFIHRDIKPDNM
LLDRTGHIKLADFGTCMKMDKDGLVRSDTAVGTPDYISPEVLKSQGSQGT
YGRECDFWSAGIFLYEMLFGETPFYADSLVATYGNIMNHRNVLSFPDDFE
IGNNAKTLICAFLTDRDQRLGRNGISDIKKHPFFKNDKWTWDDIRSSNAP
VVPELMGDDDTSNFSIMEDPDAVSEGFELTKAFTGNHLPFIGFTYSKHNS
LLTGAGGVSNGTSPTKNANNNSNNKTKSLMSENTKLLEQLNGEKNSKKEL
DNQLRNLKSKVEKMTADLAEQTEARKKVETQNRDLERERALYKHDMKEHQ
RKLEYEVNAKKQAEKKVQELQGKLDSDFDIREESTKLQRKVQGLEKENNE
VKDKLRAETDANIRLKKAESDLMKAQAIAEHSIKELSEKNRLLANAKANV
ENELLKAQVSLEAEIHSVKHAKDIRREYEKQNQGLKDEVDQLRSKYKTDA
TALQKLQDELFTLEKSKANTEFELKQLQGRFESDKKTYQSQLAKLNAEKK
EKKLSEIQILDRESADVQREREARITAESKAANLERQVNVLQLEIKNLNQ
KLTRSEQDYQASQSKVDSLKKSLDEESLKRAEIQSELNTTSNSLTVLRSQ
EKQLKSDYNRIQEEKKQLQENLFKLKSDTEVDDIQMKELQDQLEAEQYFS
TLYKTQVRELKEEVDERAKQSQALQGDLQLLQEDRDLMSRQLELALAKAE
SEELARSIVEEQFSDLEKERTMLELEVKDINARLQAEVSDKNKVYTQGED
RVKTLETTIRNKEDEIKLLEERIDQLKLDVDSAKNEKSNDTDAVESLRRQ
LATEKQLKTQAVNKLAEIIQRKDISSTKGKTKGSSTEVKKKERENKKLIM
ELREEKNKYQQFATKYQTQKYDYETQISELKEENNKMKMENDSKDMSIEQ
LGEQINNLKKDNETIRALVPDVDRQVSQQASFKMESWLSVPETAGGKKKR
RFEWKKQLVVVSSRKIFFYNTEKAKNEATPSMILDINKLYHVRSVAQGEL
IRVESKDIPKIFQILYSMEGESKSSEEKKDQQEADEKGVVSISFKSHQFF
VMTYHTPTQCDLCPKQMWNFVKPPPALQCRRCHVKMHKEHVDREEDIVEC
KADSATAKELLLMANNVDEQKQWVMNLSSKVVQPRRSDPPGIARSQSTKS
MKNKAAHRSVSMSSQHSSNIKE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043338XLOC_043338Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069540TCONS_00069540Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002219PE/DAG-bd
IPR000719Prot_kinase_dom
IPR000961AGC-kinase_C
IPR001849PH_domain
IPR011993PH_dom-like
IPR015008Rho-bd_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Biological Process
TermDefinition
GO:0035556intracellular signal transduction
GO:0006468protein phosphorylation
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0004674protein serine/threonine kinase activity
GO:0017048Rho GTPase binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
molecular_function GO:0017048 Rho GTPase binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 565..606
NoneNo IPR availableCOILSCoilCoilcoord: 857..933
NoneNo IPR availableCOILSCoilCoilcoord: 618..673
NoneNo IPR availableCOILSCoilCoilcoord: 433..523
NoneNo IPR availableCOILSCoilCoilcoord: 534..561
NoneNo IPR availableCOILSCoilCoilcoord: 945..1014
NoneNo IPR availableCOILSCoilCoilcoord: 1038..1118
NoneNo IPR availableCOILSCoilCoilcoord: 794..828
NoneNo IPR availableCOILSCoilCoilcoord: 685..786
NoneNo IPR availableGENE3D1.10.287.620coord: 527..704
e-value: 0.053
score: 12.5
NoneNo IPR availableGENE3D3.30.200.20coord: 45..142
e-value: 4.2E-21
score: 74.5
NoneNo IPR availableGENE3D1.10.510.10coord: 143..354
e-value: 1.4E-53
score: 180.4
NoneNo IPR availableGENE3D1.20.120.330coord: 1014..1130
e-value: 0.012
score: 14.8
NoneNo IPR availableGENE3D1.20.5.340coord: 710..845
e-value: 9.7E-4
score: 18.4
NoneNo IPR availableGENE3D1.20.5.730coord: 957..1013
e-value: 7.5E-10
score: 38.7
NoneNo IPR availableGENE3D1.20.58.60coord: 357..526
e-value: 5.7E-4
score: 19.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1329..1372
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 406..427
NoneNo IPR availablePRODOMPD936484coord: 454..1024
e-value: 8.0E-8
score: 144.0
NoneNo IPR availableCDDcd05596STKc_ROCKcoord: 45..396
e-value: 0.0
score: 708.759
NoneNo IPR availableCDDcd01242PH_ROCKcoord: 1132..1237
e-value: 1.60092E-38
score: 140.182
NoneNo IPR availableSUPERFAMILY103652G protein-binding domaincoord: 953..1022
NoneNo IPR availableSUPERFAMILY57889Cysteine-rich domaincoord: 1245..1293
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainSMARTSM00109c1_12coord: 1247..1300
e-value: 2.6E-6
score: 37.0
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPROSITEPS50081ZF_DAG_PE_2coord: 1246..1300
score: 9.727
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainCDDcd00029C1coord: 1247..1293
e-value: 6.98961E-9
score: 52.8796
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 72..334
e-value: 2.5E-92
score: 322.7
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 73..334
e-value: 1.9E-59
score: 201.1
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 72..334
score: 44.555
IPR000961AGC-kinase, C-terminalSMARTSM00133pkinase_C_6coord: 337..397
e-value: 1.4E-4
score: 31.3
IPR000961AGC-kinase, C-terminalPROSITEPS51285AGC_KINASE_CTERcoord: 337..405
score: 11.047
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 1132..1334
e-value: 0.0095
score: 25.1
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 1131..1332
score: 6.9
IPR011993PH domain-likeGENE3D2.30.29.30coord: 1131..1338
e-value: 2.8E-15
score: 55.7
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 1303..1335
coord: 1131..1214
IPR015008Rho binding domainPFAMPF08912Rho_Bindingcoord: 955..1023
e-value: 4.4E-9
score: 36.9
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 78..101
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 190..202
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 69..387

Blast
[Close]
BLAST of TCONS_00069540-protein vs. Swiss-Prot (Human)
Match: ROCK2 (Rho-associated protein kinase 2 OS=Homo sapiens GN=ROCK2 PE=1 SV=4)

HSP 1 Score: 1117.84 bits (2890), Expect = 0.000e+0
Identity = 605/1340 (45.15%), Postives = 874/1340 (65.22%), Query Frame = 0 
Query:    6 RYQALEEQIKNPRNELYVEGLLDSITSIYHDCDYPSIRKEKNFENFLNRYGHLAKEIEKSRVNITDFNLIRVIGRGAFGEVQLVRHKDNKTVYAMKSLSKFEMIKRSESAFFWEERDIMAHSNSDWIISLHYAFQDEKFLYMIMDYMPGGDLVNLIETYDIPEGWAKFYLAELILALDAIHSMGFIHRDIKPDNMLLDRTGHIKLADFGTCMKMDKDGLVRSDTAVGTPDYISPEVLKSQGSQGTYGRECDFWSAGIFLYEMLFGETPFYADSLVATYGNIMNHRNVLSFPDDFEIGNNAKTLICAFLTDRDQRLGRNGISDIKKHPFFKNDKWTWDDIRSSNAPVVPELMGDDDTSNFSIMEDPDAVSEGFELTKAFTGNHLPFIGFTYSKHNSLLTGAGGVSNGTSPTKNANNNSNNKTKSLMSENTKLLEQLNGEKNSKKELDNQLRNLKSKVEKMTADLAEQTEARKKVETQNRDLERERALYKHDMKEHQRKLEYEVNAKKQAEKKVQELQGKLDSDFDIREESTKLQ-RKVQGLEKENNEVKDKLRAETDANIRLKKAESDLMKAQAIAEHSIKELSEKNRLLANAKANVENELLKAQVSLEAEIHSVKHAKDIRREYEKQNQGLKDEVDQLRSKYKTDATALQKLQDELFTLEKSKANTE----FELKQLQGRFESDKKTYQSQLAKLNAEKKEKKLSEIQILDRESADVQREREARI----TAESKAANL----ERQVNVLQLEIKNLNQKLTRSEQDYQASQSKVDSLKKSLDEESLKRAEIQSELNTTSNSLTVLRSQEKQLKSDYNRIQEEKKQLQENLFKLKSDTEVDDIQMKELQDQLEAEQYFSTLYKTQVRELKEEVDERAKQSQALQGDLQLLQEDRDLMSRQLELALAKAESEELARSIVEEQFSDLEKERTMLELEVKDINARLQAEVSDKNKVYTQGEDRVKTLETTIRNKEDEIKLLEERIDQLKLDVDSAKNEKSNDTDAVESLRRQLATEKQLKTQAVNKLAEIIQRKDISSTKGKTKGSSTEVKKKERENKKLIMELREEKNKYQQFATKYQTQKYDYETQISELKEENNKMKMENDSKDMSIEQLGEQINNLK--KDNETIRALVPDVDRQVSQQASFKMESWLSVPETAGGKKKRRFEWKKQLVVVSSRKIFFYNTEKAKNEATPSMILDINKLYHVRSVAQGELIRVESKDIPKIFQILYSMEGESKSSEEKKDQQEADEKGVVSISFKSHQFFVMTYHTPTQCDLCPKQMWNFVKPPPALQCRRCHVKMHKEHVDREEDIV-ECKA--DSATAKELLLMANNVDEQKQWVMNL 1327
            R + LE  I++PR+ + VE LLD + S+  D D+P++RK KN +NFLNRY  + K+I   ++   D+++++VIGRGAFGEVQLVRHK ++ VYAMK LSKFEMIKRS+SAFFWEERDIMA +NS W++ L YAFQD+++LYM+M+YMPGGDLVNL+  YD+PE WAKFY AE++LALDAIHSMG IHRD+KPDNMLLD+ GH+KLADFGTCMKMD+ G+V  DTAVGTPDYISPEVLKSQG  G YGRECD+WS G+FLYEML G+TPFYADSLV TY  IM+H+N L FP+D EI  +AK LICAFLTDR+ RLGRNG+ +I++HPFFKND+W WD+IR + APVVPEL  D D+SNF  +ED     E F + KAF GN LPFIGFTY + N LL+ +       S     N  S    K L +    L E L+ E  +K+EL+ + +++ +++EK   +L E+   RK VE+  R LERE+AL +H   E+QRK ++E + K+  E  V  L+ +L+ D   R +++++   KV  L+++ +E    LR E+D   RL+K +++  K     E + ++L +KN LL  AK  +E E +  Q +LE+E     H  +I  + + +  GL++++   +          ++LQ+    LEK K+N E    ++LK +Q   E ++  +++  A+L A+K   K+ E   ++   ++  +E E ++    T + K  NL    E++ ++L  ++K   QK+    +        V +L   +++E+ KR   Q++L   +  +  L+  EKQLK + N + E K  L++   +L+ + +  D QMKELQDQLEAEQYFSTLYKTQVRELKEE +E+ K  + LQ   Q LQ++RD ++ QLE+ L KA+SE+LARSI EEQ+SDLEKE+ M ELE+K++ AR + E+++K+      E+  +TL + + N  +E + L  ++  ++  +   K+E+ +         +QL TE+ LKTQAVNKLAEI+ RK+        +G+ T+V++KE+EN+KL MEL+ E+ K  Q   KYQ +  + + QI+E  +   +++M  DSKD  IEQL  Q+  L    D+ +I +   D +       S ++E WLS+P     KK   F W K+ V+VSS+KI FY++E+ K ++ P M+LDI+KL+HVR V Q ++ R ++K+IP+IFQILY+ EGESK  +E   +   ++     I  K H+F    YH PT C+ C K +W+  KPPPAL+CRRCH+K HK+H+D++E+I+  CK   D +TAK LLL+AN+ +EQ++WV  L
Sbjct:   26 RQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYT----LEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLE-DLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARL-ADK--NKIYE--SIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVK-----RGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPES-RLEGWLSLPVRNNTKK---FGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNY--ICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRL 1344
The following BLAST results are available for this feature:
BLAST of TCONS_00069540-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ROCK20.000e+045.15Rho-associated protein kinase 2 OS=Homo sapiens GN... [more]
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