TCONS_00072387-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00072387-protein
Unique NameTCONS_00072387-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length187

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00072387-protein ID=TCONS_00072387-protein|Name=TCONS_00072387-protein|organism=Clytia hemisphaerica|type=polypeptide|length=187bp
GMQYVADLNIVHRDLACRNILVGYNRVCKVADFGLAKKVGDNGIYQRTEQ
AKLPVKWLPPESIKYGRSSLQSDIWSYGIMMWEIVTIGAVPYPGHKSKEI
PGLLNKGYRMEKPLHCKEELYELMLQCWSEDEKKRPNFKFIHQKLERMIE
GLSTYINLEAYSDDSYLTFGAGDEILDEDEMIDIEDE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044948XLOC_044948Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00072387TCONS_00072387Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 116..138
score: 46.26
coord: 53..63
score: 55.33
coord: 4..22
score: 57.8
coord: 72..94
score: 57.19
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 1..145
e-value: 6.0E-57
score: 192.8
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 1..145
e-value: 2.0E-24
score: 97.1
NoneNo IPR availableGENE3D1.10.510.10coord: 1..160
e-value: 2.6E-39
score: 134.5
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 10..22
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1..145
score: 24.796
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1..157

Blast
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BLAST of TCONS_00072387-protein vs. Swiss-Prot (Human)
Match: RET (Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo sapiens GN=RET PE=1 SV=3)

HSP 1 Score: 174.096 bits (440), Expect = 1.779e-50
Identity = 80/180 (44.44%), Postives = 118/180 (65.56%), Query Frame = 0 
Query:    1 GMQYVADLNIVHRDLACRNILVGYNRVCKVADFGLAKKVGDNGIYQRTEQAKLPVKWLPPESIKYGRSSLQSDIWSYGIMMWEIVTIGAVPYPGHKSKEIPGLLNKGYRMEKPLHCKEELYELMLQCWSEDEKKRPNFKFIHQKLERMIEGLSTYINLEAYSDDSYLTFGAGDEILDEDE 180
            GMQY+A++ +VHRDLA RNILV   R  K++DFGL++ V +   Y +  Q ++PVKW+  ES+     + QSD+WS+G+++WEIVT+G  PYPG   + +  LL  G+RME+P +C EE+Y LMLQCW ++  KRP F  I + LE+M+     Y++L A +    L +   D+ L E+E
Sbjct:  861 GMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIY---DDGLSEEE 1037
The following BLAST results are available for this feature:
BLAST of TCONS_00072387-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RET1.779e-5044.44Proto-oncogene tyrosine-protein kinase receptor Re... [more]
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