TCONS_00003439-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00003439-protein
Unique Name	TCONS_00003439-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	934

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00003439-protein ID=TCONS_00003439-protein|Name=TCONS_00003439-protein|organism=Clytia hemisphaerica|type=polypeptide|length=934bp
MPPQANSGAALPTPPSTTSTGVTVVDQYGEEEDDSCCRNLTNTINGALEN
FFAAIGRGVANNPWKVIIISLVLSLLCMVGVLELQSENRGEKNWVSQTSD
PIKHKEWIDDVFPIPSRTSKLLLEKKDGSDLLTRDGLLKLYEEDQKVKGM
LFNKTGYQWTDICYSAAGSACIPTSVLELWSYDRAIISNLTNDQIKATIN
SQGLVSPMTGQNITIERLVGGPVKRGQNGDIEEASVLKVDYRLKKQDIFD
EGSGRDVDQYADAWEEELEKTFENGDADYVIFTYSLWANDKASEDASNGD
LQFFVVGYILVIIYLSIMLGSFSRIGHKILLAIAGIGVIGISIGIAYGLG
SAFQLKYTGVHNVLPFLLLGIGVDDLFVIVQSWDNIGGPIRDHRTIPEKI
SLAMRHAGVSVLVTSVTDICAFAIGSATILPALRSFSVWCAIGILAIFLL
TITLFTALLTLDARRQEKERDACCCCLKLSSDYEPPSCSETKYLKGFLKN
YYARVILSTPGKVIVLIAVAGLLGGGFYGMTELEQNFDFVWFLPTDSRPR
MFIEKDRIAFPGNGVPGDIYIGRIDYWKDGHVHMDKIKTALENDKFVSEG
TVSSWFHHYNEWLHQNHRDMLEDNCVAINKCKTKNDTVFYQLLDVFLAGE
GKHYKSLIKMDDKRIRASKIQYTHIQLVGSVQQVDAMDSITGTIKPGLIP
DGGEEILPFAFNQNYINWSTNKVISTELVRNIALAGACVLVVTLFLLSNL
VASLLVVACVAFSLIEIAAFMGFWGLTIDTVTTIILVIAIGLTVDYSVHI
AHGFMASRAGDRNQRMTEALYEVGPAVFHGGFSTFLAFALLSASQSYVFL
TFFKVFFLVVIFGMFHGMVFLPVMLSLIGPAPYADHKASKDNAGSQPTDV
QRQISQPKGRPSERDHEMVIVIEKGSDNTAYVKE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_001917	XLOC_001917	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00003439	TCONS_00003439	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR003392	Ptc/Disp
IPR000731	SSD

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016021	integral component of membrane

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003392	Protein patched/dispatched	PFAM	PF02460	Patched	coord: 158..878 e-value: 7.1E-95 score: 318.7
None	No IPR available	GENE3D	1.20.1640.10		coord: 661..881 e-value: 1.4E-34 score: 118.7
None	No IPR available	GENE3D	1.20.1640.10		coord: 248..473 e-value: 1.5E-37 score: 128.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..20
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 888..918
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 254..461
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 713..879
IPR000731	Sterol-sensing domain	PROSITE	PS50156	SSD	coord: 300..461 score: 34.043
IPR000731	Sterol-sensing domain	PROSITE	PS50156	SSD	coord: 751..877 score: 11.874

Blast

[Close]

BLAST of TCONS_00003439-protein vs. Swiss-Prot (Human)
Match: NPC1 (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 219.55 bits (558), Expect = 8.271e-59
Identity = 227/957 (23.72%), Postives = 418/957 (43.68%), Query Frame = 0

Query:   30 EEEDDSCCRNLTNTINGALENFFAAIGRGVANNPWKVIIISLVLSLLCMVGVLELQSENRGEKNWVSQTSDPIKHKEWIDDVFPIPSRTSKLLLEKK-----------DGSDLLTRDGL--------LKLYEEDQKVKGMLFNKTGYQWTDICY---SAAGSACIPTSVLELWSYDRAIISNLTNDQ--IKATINSQGLVSPMTGQNITIERLV--------GGPV------KRGQNGDIEEASVLKVDYRLKKQDIFDEGSGRDVDQYADAWEEEL---EKTFENGDADYVIFTYSLWANDKASEDASNGDLQFFVVGYILVIIYLSIMLGSFSR-----IGHKILLAIAGIGVIGISIGIAYGLGSAFQLKYTG-VHNVLPFLLLGIGVDDLFVIVQSWDNIGGPIRDHR----TIPEKISLAMRHAGVSVLVTSVTDICAFAIGSATILPALRSFSVWCAIGILAIFLLTITLFTALLTLDARRQEKERDACCCCLKLSSDYEPPSCSETKYLKGFLKNYYARVILSTPGKVIVLIAVAGLLGGGFYGMTELEQNFDFVWFLPTDSR----------------PRMFIEKDRIAFPGNGVPGDIYIGRIDYWKDGHVHMDKIKTALENDKFVSEG-TVSSWFHHYNEWLHQNHRDMLEDNCV-----------AINKCKT--------KNDTVFYQLLDVFLA-------GEGKH--YKSLIKM---DDKRIRASKIQYTHIQLVGSVQQVDAMDS---ITGTIKPGLIPDGGEEILPFAFNQNYINWSTNKVISTELVRNIALAGACVLVVTLFLL-SNLVASLLVVACVAFSLIEIAAFMGFWGLTIDTVTTIILVIAIGLTVDYSVHIAHGFMASRAGDRNQRMTEALYEVGPAVFHG-GFSTFLAFALLSASQSYVFLTF-FKVFFLVVIFGMFHGMVFLPVMLSLIGPA 881
            ++ + SCC  ++    G L   F   G     NP  VI  SLV    C  G++ ++        W + +S     KE+ D  F    RT +L++               G+D+     L        L L    + +     N+T     DIC    S   + C   SVL  +    +++ +   D   + A  ++  L       ++    L+        GGPV          + +   A+ L + + +      +  +  +  Q A AWE+E     K ++N +   + FT      D+ + + S+ D+   V+ Y ++ +Y+S+ LG         +  K+ L IAGI ++  S+  + G+ S   L  T  V  V+PFL+L +GVD++F++VQ++       RD R    T+ +++   +     S+ ++S ++  AF +G+ +++PA+ +FS++  + +   FLL IT F +LL LD +RQEK R    CC++ + D      SE+   + F KN Y+ ++L    + IV+    G+L      + +++   D    +P DS                 P  F+ ++   +  +    ++  G +    D  V   +I  A + D +   G   SSW   Y +W+         DN             A  +C+              F + L +FL+       G+G H  Y S + +      R+ A+     H  L  S   +DA+     I   +   +  +G    + F ++  Y+ +     I  + + N+ ++   + +VT+ LL   L +++++ A +A  L+ +   M  WG++++ V+ + LV++ G++V++  HI   F  S  G R +R  EAL  +G +VF G   + F    +L+ ++S +F  F F+++  +V+ G  HG++FLPV+LS IGP+
Sbjct:  317 DKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNET-VTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVN-----NYYNDTEKLQRAQAWEKEFINFVKNYKNPNLT-ISFTAERSIEDELNRE-SDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQ------RDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFR-FFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSK-GQNMVCGGMGCNNDSLVQ--QIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRV-FPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPS 1254

The following BLAST results are available for this feature:

BLAST of TCONS_00003439-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00003439-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NPC1	8.271e-59	23.72	Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE...	[more]

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TCONS_00003439-protein (polypeptide) - C. hemisphaerica