TCONS_00004199-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004199-protein
Unique NameTCONS_00004199-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length778

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004199-protein ID=TCONS_00004199-protein|Name=TCONS_00004199-protein|organism=Clytia hemisphaerica|type=polypeptide|length=778bp
MNKYEVIGIVGEGAYGVVMKCRHKETNDIVAIKKFKDGEDNEDMKRTTLR
ELKVLRMLKQENIVQLREAFRKRGKLYLVFEYVEKNMLELLERTPNGVPI
PQLKSYIKQLNKAVQWCHQNDVIHRDIKPENLLISNTGLLKLCDFGFARS
ITDSGTGQYTDYVATRWYRSPELLLGGGYGKAVDIWSIGCILGELSDGQP
VFPGESEIDQLYVIQKLIGPLPPAQMHLFNINHRFRGLKFPAITNPLTLK
KRYSGILSTDLLDYMEKVLQLEPQKRLNISQCVDHYAFTDGGGGGGGQKK
KAPSEPTDVDSGSNIEDESIHEEEWLETKPTKHKTKSLLKDTSHKISSPK
VTAKPKAMKHSNKAQQQQQSSSLIQQYSFAFHSTKNEDGDKIDKYSNSTS
SPRSSHSSVEDDDYDSRSPVHSQPSKPINSYNSNKVETPSKEKRSQKQPH
QKPKQSITSNFASPASSSHQTYYQAKPDLLNNLPTVSNPKAKSSDKIKKS
KKTSKRNELTQLKSMRQNDVISTTSQHEISMTSSRYRTDDGIPEVIHKPT
LSPKVGREKMTENQILTRYDAVNKKRRKNKKDPSLPKSRQRTQDLYEASD
GGQDKYGDQHSEGRRTKMSNFSYYGGGITPSESRTAEKDPLVQRLSIGEL
RLNPLQKKSSKGQVNVGGRNTNAPTQYHMSGDSGRFGAHQDISPRASKKG
SYDSIPPEQIFHAPENLQPVRRYAKSRTESRLEDNNGLLEMKLNGLSPEP
LRPIASFKSKSDFDNEYRYKSSFKDHFP
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002346XLOC_002346Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004199TCONS_00004199Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 4..288
e-value: 1.4E-87
score: 306.9
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 4..286
e-value: 6.9E-71
score: 238.6
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 4..288
score: 45.092
NoneNo IPR availableGENE3D3.30.200.20coord: 1..68
e-value: 2.3E-24
score: 85.0
NoneNo IPR availableGENE3D1.10.510.10coord: 69..292
e-value: 3.3E-57
score: 192.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 290..719
NoneNo IPR availableCDDcd07833STKc_CDKLcoord: 2..288
e-value: 2.85471E-165
score: 481.047
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 10..34
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 122..134
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1..289

Blast
BLAST of TCONS_00004199-protein vs. Swiss-Prot (Human)
Match: CDKL5 (Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1)

HSP 1 Score: 457.218 bits (1175), Expect = 4.880e-147
Identity = 199/288 (69.10%), Postives = 247/288 (85.76%), Query Frame = 0
Query:    1 MNKYEVIGIVGEGAYGVVMKCRHKETNDIVAIKKFKDGEDNEDMKRTTLRELKVLRMLKQENIVQLREAFRKRGKLYLVFEYVEKNMLELLERTPNGVPIPQLKSYIKQLNKAVQWCHQNDVIHRDIKPENLLISNTGLLKLCDFGFARSITDSGTGQYTDYVATRWYRSPELLLGGGYGKAVDIWSIGCILGELSDGQPVFPGESEIDQLYVIQKLIGPLPPAQMHLFNINHRFRGLKFPAITNPLTLKKRYSGILSTDLLDYMEKVLQLEPQKRLNISQCVDHYAF 288
            MNK+E++G+VGEGAYGVV+KCRHKET++IVAIKKFKD E+NE++K TTLRELK+LR LKQENIV+L+EAFR+RGKLYLVFEYVEKNMLELLE  PNGVP  ++KSYI QL KA+ WCH+ND++HRDIKPENLLIS+  +LKLCDFGFAR++++     YT+YVATRWYRSPELLLG  YGK+VD+WS+GCILGELSDGQP+FPGESEIDQL+ IQK++GPLP  QM LF  N RF GL+FPA+ +P +L++RY GIL++ LLD M+ +L+L+P  R    QC++H  F
Sbjct:   10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF 297          
The following BLAST results are available for this feature:
BLAST of TCONS_00004199-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CDKL54.880e-14769.10Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=... [more]
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