MITF (polypeptide) - C. hemisphaerica

Overview
NameMITF
Unique NameTCONS_00004219-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length477

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004219-protein ID=TCONS_00004219-protein|Name=MITF|organism=Clytia hemisphaerica|type=polypeptide|length=477bp
MTCLWNENPSFLMDPDVKIKPDPDDQAMNMQTMEIMNRTNFKQALERERI
MEVERKEQMKGSQLPQQQTFLMKQQNTTHLQQNIQQQQQQPQQQQQQPQQ
QQRFFNNSNPVSFQTQRTVNNQNKGIKANMPAMSLPSSVLKVETKLQNPT
SYYLKQQQKRQVREYLEQNNQLSTNMPVSVPTALQQNYNFSSEFSSPSFM
NSFGGNPMSPNSPDAASSVASGGESNDFFEDLFSEDLNIFSATLPTNNNL
LDTYVNNPTQKNEENQISISSSCPANVKQEEPDTFFNKERQKKDNHNMIE
RRRRYNINDRIKELGTLVPKIDNDMKQNKGTILKSSVDYIRRLKKDRERL
RNVEHRSQSLEDINKKLLLRVQELELILRASNITTTLPEPDLSSAASPQL
TQLLLNKQLSQQQNSAQPTPQQQAAAFLLHKQQISTSLHELLKAPPGTSS
ETTAMSSSSVDSPRRMEDDDDCVIMDE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002350XLOC_002350Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004219TCONS_00004219Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR011598bHLH_dom
IPR031867MiT/TFE_N
Vocabulary: Molecular Function
TermDefinition
GO:0046983protein dimerization activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0046983 protein dimerization activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 155..175
NoneNo IPR availableCOILSCoilCoilcoord: 343..363
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 75..102
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 201..222
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 438..477
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainSMARTSM00353finuluscoord: 297..349
e-value: 6.7E-15
score: 65.5
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPFAMPF00010HLHcoord: 292..343
e-value: 1.2E-16
score: 60.3
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainGENE3D4.10.280.10coord: 290..375
e-value: 1.6E-20
score: 72.5
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainPROSITEPS50888BHLHcoord: 291..343
score: 17.028
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainCDDcd00083HLHcoord: 289..348
e-value: 9.66032E-15
score: 68.0095
IPR011598Myc-type, basic helix-loop-helix (bHLH) domainSUPERFAMILY47459HLH, helix-loop-helix DNA-binding domaincoord: 287..352
IPR031867MiT/TFE transcription factors, N-terminalPFAMPF15951MITF_TFEB_C_3_Ncoord: 80..225
e-value: 1.2E-14
score: 55.2

Blast
BLAST of MITF vs. Swiss-Prot (Human)
Match: TFE3 (Transcription factor E3 OS=Homo sapiens GN=TFE3 PE=1 SV=4)

HSP 1 Score: 186.808 bits (473), Expect = 1.043e-52
Identity = 122/294 (41.50%), Postives = 173/294 (58.84%), Query Frame = 0
Query:  131 PAMSLPSSVLKVETKLQNPTSYYLKQQQKRQVREYLEQNNQLSTNMPVSVPTALQQNYNFSSE--FSSPSFMNSFGGNPMSPNSPDAASSVASGGES--NDFFEDLFS-------EDLNIFSA---------TLPTNNNLLDTYVNNPTQKNEENQISISSSCPA---NVKQEEPDT---FFNKERQKKDNHNMIERRRRYNINDRIKELGTLVPKI-DNDMKQNKGTILKSSVDYIRRLKKDRERLRNVEHRSQSLEDINKKLLLRVQELELILRASNITTTLPEPDLSSAAS 397
            P   +P  VLKV+T L+NPT Y+L+Q +++QV++YL      +T  P     AL      +S     +P   ++ G    +PNSP A  ++ S  E   +D  +++ S       E L+             TLP + NLLD Y    +Q      I++S+SCPA   N+K+E  +T      KERQKKDNHN+IERRRR+NINDRIKELGTL+PK  D +M+ NKGTILK+SVDYIR+L+K+++R +++E R +SLE  N+ L LR+QELEL  +   +    P P L S A+
Sbjct:  168 PPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLS-----TTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYS---SQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVP-PTPGLLSLAT 452          
The following BLAST results are available for this feature:
BLAST of MITF vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TFE31.043e-5241.50Transcription factor E3 OS=Homo sapiens GN=TFE3 PE... [more]
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