TCONS_00004226-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004226-protein
Unique NameTCONS_00004226-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length467

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004226-protein ID=TCONS_00004226-protein|Name=TCONS_00004226-protein|organism=Clytia hemisphaerica|type=polypeptide|length=467bp
MKETAIQTRDFVEKEMDAGIKRKSEDHPNEDFEKRAKYAYLGKIPNVNDT
NTPCIVFSLPEEVGVLADALKIFKKRQINLKHIESRPSKSNKKDYEFYVD
IDAETANSESVKLVVEDLKSKAKSVVLHNEESVPWFPRKIADLDKFADRV
LSYGSELDSEHPGFTDPVYRARRKEFADIAIKYRHGEPLPRVTYTEDEIS
VWNTVFSELTKLFPKYACREVNFMLPLLVENCNYRIGAIPQLEDVSKFLK
DCTGFTLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHAKTPMYTPEPDCVH
ELIGHVPLFADPSFAQFSQEIGLASLGAPDEWIEKLATLYWFTVEFGLCR
QDGEIKAYGAGLLSSFGELQYCVSDKPEHLAFDPEKTSQTKYPITEFQPR
YFVAESFEDAKEKVRKWANHIPKPFALHFNPYTQIVETLDRKEQVLKLIE
DVRGELDHVSTALSKQQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002353XLOC_002353Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004226TCONS_00004226Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR019774Aromatic-AA_hydroxylase_C
IPR002912ACT_dom
IPR001273ArAA_hydroxylase
IPR019773Tyrosine_3-monooxygenase-like
IPR018301ArAA_hydroxylase_Fe/CU_BS
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0009072aromatic amino acid family metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0016714oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0005506iron ion binding
GO:0004497monooxygenase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0009072 aromatic amino acid family metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0005506 iron ion binding
molecular_function GO:0004497 monooxygenase activity
molecular_function GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019774Aromatic amino acid hydroxylase, C-terminalPRINTSPR00372FYWHYDRXLASEcoord: 162..181
score: 69.35
coord: 388..407
score: 51.96
coord: 317..336
score: 84.13
coord: 253..275
score: 86.01
coord: 357..375
score: 71.17
coord: 423..441
score: 46.22
IPR019774Aromatic amino acid hydroxylase, C-terminalPFAMPF00351Biopterin_Hcoord: 134..463
e-value: 3.3E-167
score: 555.5
IPR019774Aromatic amino acid hydroxylase, C-terminalPROSITEPS51410BH4_AAA_HYDROXYL_2coord: 121..467
score: 139.743
IPR019774Aromatic amino acid hydroxylase, C-terminalSUPERFAMILY56534Aromatic aminoacid monoxygenases, catalytic and oligomerization domainscoord: 133..465
IPR002912ACT domainPFAMPF01842ACTcoord: 55..116
e-value: 6.5E-7
score: 28.9
IPR002912ACT domainPROSITEPS51671ACTcoord: 54..134
score: 14.02
IPR001273Aromatic amino acid hydroxylaseGENE3D1.10.800.10coord: 43..444
e-value: 4.3E-187
score: 621.2
IPR019773Tyrosine 3-monooxygenase-likePIRSFPIRSF000336THcoord: 1..467
e-value: 1.7E-196
score: 651.6
IPR018301Aromatic amino acid hydroxylase, iron/copper binding sitePROSITEPS00367BH4_AAA_HYDROXYL_1coord: 296..307
NoneNo IPR availableCDDcd03347eu_PheOHcoord: 134..439
e-value: 0.0
score: 593.653
NoneNo IPR availableCDDcd04880ACT_AAAH-PDT-likecoord: 55..125
e-value: 7.57813E-23
score: 91.0174
NoneNo IPR availableSUPERFAMILY55021ACT-likecoord: 48..140

Blast
[Close]
BLAST of TCONS_00004226-protein vs. Swiss-Prot (Human)
Match: PH4H (Phenylalanine-4-hydroxylase OS=Homo sapiens GN=PAH PE=1 SV=1)

HSP 1 Score: 529.635 bits (1363), Expect = 0.000e+0
Identity = 249/423 (58.87%), Postives = 316/423 (74.70%), Query Frame = 0 
Query:   46 NVNDTNTPCIVFSLPEEVGVLADALKIFKKRQINLKHIESRPSKSNKKDYEFYVDIDAET--ANSESVKLVVEDLKSKAKSVVL-HNEESVPWFPRKIADLDKFADRVLSYGSELDSEHPGFTDPVYRARRKEFADIAIKYRHGEPLPRVTYTEDEISVWNTVFSELTKLFPKYACREVNFMLPLLVENCNYRIGAIPQLEDVSKFLKDCTGFTLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHAKTPMYTPEPDCVHELIGHVPLFADPSFAQFSQEIGLASLGAPDEWIEKLATLYWFTVEFGLCRQDGEIKAYGAGLLSSFGELQYCVSDKPEHLAFDPEKTSQTKYPITEFQPRYFVAESFEDAKEKVRKWANHIPKPFALHFNPYTQIVETLDRKEQVLKLIEDVRGELDHVSTALSK 465
            N N      ++FSL EEVG LA  L++F++  +NL HIESRPS+  K +YEF+  +D  +  A +  +K++  D+ +    +     +++VPWFPR I +LD+FA+++LSYG+ELD++HPGF DPVYRARRK+FADIA  YRHG+P+PRV Y E+E   W TVF  L  L+  +AC E N + PLL + C +    IPQLEDVS+FL+ CTGF LRPVAGLLSSRDFL GLAFRVFH TQYIRH   PMYTPEPD  HEL+GHVPLF+D SFAQFSQEIGLASLGAPDE+IEKLAT+YWFTVEFGLC+Q   IKAYGAGLLSSFGELQYC+S+KP+ L  + EKT+   Y +TEFQP Y+VAESF DAKEKVR +A  IP+PF++ ++PYTQ +E LD  +Q+  L + +  E+  + +AL K
Sbjct:   28 NCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQK 450
The following BLAST results are available for this feature:
BLAST of TCONS_00004226-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PH4H0.000e+058.87Phenylalanine-4-hydroxylase OS=Homo sapiens GN=PAH... [more]
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